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Aliases for GPATCH2L Gene

Aliases for GPATCH2L Gene

  • G-Patch Domain Containing 2 Like 2 3 5
  • C14orf118 3 4
  • Chromosome 14 Open Reading Frame 118 2
  • G Patch Domain Containing 2-Like 3
  • KIAA1152 4

External Ids for GPATCH2L Gene

Previous HGNC Symbols for GPATCH2L Gene

  • C14orf118

Previous GeneCards Identifiers for GPATCH2L Gene

  • GC14P076619

Summaries for GPATCH2L Gene

GeneCards Summary for GPATCH2L Gene

GPATCH2L (G-Patch Domain Containing 2 Like) is a Protein Coding gene. An important paralog of this gene is GPATCH2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GPATCH2L Gene

Genomics for GPATCH2L Gene

Regulatory Elements for GPATCH2L Gene

Enhancers for GPATCH2L Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around GPATCH2L on UCSC Golden Path with GeneCards custom track

Promoters for GPATCH2L Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around GPATCH2L on UCSC Golden Path with GeneCards custom track

Genomic Location for GPATCH2L Gene

Chromosome:
14
Start:
76,151,885 bp from pter
End:
76,254,342 bp from pter
Size:
102,458 bases
Orientation:
Plus strand

Genomic View for GPATCH2L Gene

Genes around GPATCH2L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GPATCH2L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GPATCH2L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GPATCH2L Gene

Proteins for GPATCH2L Gene

  • Protein details for GPATCH2L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NWQ4-GPT2L_HUMAN
    Recommended name:
    G patch domain-containing protein 2-like
    Protein Accession:
    Q9NWQ4
    Secondary Accessions:
    • B3KN42
    • Q6PEJ7
    • Q9H3M3
    • Q9NWH0
    • Q9ULR8

    Protein attributes for GPATCH2L Gene

    Size:
    482 amino acids
    Molecular mass:
    54260 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA86466.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=BAA91325.1; Type=Frameshift; Positions=344; Evidence={ECO:0000305}; Sequence=BAA91411.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for GPATCH2L Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for GPATCH2L Gene

Proteomics data for GPATCH2L Gene at MOPED

Post-translational modifications for GPATCH2L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for GPATCH2L Gene

Domains & Families for GPATCH2L Gene

Protein Domains for GPATCH2L Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with GPATCH2L: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for GPATCH2L Gene

Function for GPATCH2L Gene

genes like me logo Genes that share phenotypes with GPATCH2L: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GPATCH2L Gene

Localization for GPATCH2L Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for GPATCH2L Gene COMPARTMENTS Subcellular localization image for GPATCH2L gene
Compartment Confidence
nucleus 4
cytosol 3

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for GPATCH2L Gene

Pathways & Interactions for GPATCH2L Gene

SuperPathways for GPATCH2L Gene

No Data Available

Gene Ontology (GO) - Biological Process for GPATCH2L Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GPATCH2L Gene

Drugs & Compounds for GPATCH2L Gene

No Compound Related Data Available

Transcripts for GPATCH2L Gene

Unigene Clusters for GPATCH2L Gene

G patch domain containing 2-like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for GPATCH2L Gene

ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3a · 3b · 3c ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14a · 14b ^ 15a ·
SP1: - - - -
SP2: - - - - - - -
SP3: - - -
SP4: - - - - -
SP5: - - - -
SP6: -
SP7: - -
SP8:
SP9:

ExUns: 15b · 15c · 15d
SP1:
SP2:
SP3:
SP4:
SP5:
SP6:
SP7:
SP8:
SP9:

Relevant External Links for GPATCH2L Gene

GeneLoc Exon Structure for
GPATCH2L
ECgene alternative splicing isoforms for
GPATCH2L

Expression for GPATCH2L Gene

mRNA expression in normal human tissues for GPATCH2L Gene

Protein differential expression in normal tissues from HIPED for GPATCH2L Gene

This gene is overexpressed in Lung (67.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for GPATCH2L Gene



SOURCE GeneReport for Unigene cluster for GPATCH2L Gene Hs.410231

genes like me logo Genes that share expression patterns with GPATCH2L: view

Protein tissue co-expression partners for GPATCH2L Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for GPATCH2L Gene

Orthologs for GPATCH2L Gene

This gene was present in the common ancestor of chordates.

Orthologs for GPATCH2L Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia GPATCH2L 35
  • 92.49 (n)
  • 98.12 (a)
MGC166084 36
  • 92 (a)
OneToOne
dog
(Canis familiaris)
Mammalia GPATCH2L 35
  • 92.48 (n)
  • 94.78 (a)
GPATCH2L 36
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gpatch2l 35
  • 85.42 (n)
  • 87.9 (a)
Gpatch2l 16
Gpatch2l 36
  • 86 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia C14H14orf118 35
  • 99.93 (n)
  • 100 (a)
C14H14orf118 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Gpatch2l 35
  • 86.77 (n)
  • 88.32 (a)
oppossum
(Monodelphis domestica)
Mammalia GPATCH2L 36
  • 77 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia GPATCH2L 36
  • 63 (a)
OneToOne
chicken
(Gallus gallus)
Aves C5H14ORF118 35
  • 77.92 (n)
  • 85.12 (a)
GPATCH2L 36
  • 80 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia GPATCH2L 36
  • 76 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 24 (a)
OneToMany
Species with no ortholog for GPATCH2L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for GPATCH2L Gene

ENSEMBL:
Gene Tree for GPATCH2L (if available)
TreeFam:
Gene Tree for GPATCH2L (if available)

Paralogs for GPATCH2L Gene

Paralogs for GPATCH2L Gene

(2) SIMAP similar genes for GPATCH2L Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with GPATCH2L: view

Variants for GPATCH2L Gene

Sequence variations from dbSNP and Humsavar for GPATCH2L Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs17104086 - 76,154,758(+) GAAGG(A/T)GAAGC nc-transcript-variant, reference, missense
rs8799 -- 76,214,216(+) AAGAA(A/C/T)AGGAG utr-variant-3-prime
rs14500 -- 76,177,785(+) CCTTC(C/T)TTGTC intron-variant
rs2543380 -- 76,153,403(+) GTTTG(C/T)CTCTG intron-variant, upstream-variant-2KB
rs2543381 -- 76,157,732(+) CAATC(A/C)GCTTA intron-variant

Variation tolerance for GPATCH2L Gene

Residual Variation Intolerance Score: 14.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.13; 22.94% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for GPATCH2L Gene

HapMap Linkage Disequilibrium report
GPATCH2L

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for GPATCH2L Gene

Disorders for GPATCH2L Gene

Relevant External Links for GPATCH2L

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
GPATCH2L

No disorders were found for GPATCH2L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GPATCH2L Gene

Publications for GPATCH2L Gene

  1. Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PMID: 10574461) Hirosawa M. … Ohara O. (DNA Res. 1999) 2 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. (PMID: 26673895) KA+rlA+ K. … GAPrlich D. (Elife 2015) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. A Y2H-seq approach defines the human protein methyltransferase interactome. (PMID: 23455924) Weimann M. … Stelzl U. (Nat. Methods 2013) 3

Products for GPATCH2L Gene

Sources for GPATCH2L Gene

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