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Aliases for GPATCH11 Gene

Aliases for GPATCH11 Gene

  • G Patch Domain Containing 11 2 3
  • Coiled-Coil Domain-Containing Protein 75 3 4
  • Coiled-Coil Domain Containing 75 2 3
  • Centromere Protein Y 2 3
  • CCDC75 3 4
  • G Patch Domain-Containing Protein 11 3
  • CENP-Y 3
  • CENPY 3

External Ids for GPATCH11 Gene

Previous HGNC Symbols for GPATCH11 Gene

  • CCDC75

Previous GeneCards Identifiers for GPATCH11 Gene

  • GC02P037314

Summaries for GPATCH11 Gene

GeneCards Summary for GPATCH11 Gene

GPATCH11 (G Patch Domain Containing 11) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GPATCH11 Gene

Genomics for GPATCH11 Gene

Genomic Location for GPATCH11 Gene

37,084,451 bp from pter
37,099,244 bp from pter
14,794 bases
Plus strand

Genomic View for GPATCH11 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for GPATCH11 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GPATCH11 Gene

No data available for Regulatory Elements for GPATCH11 Gene

Proteins for GPATCH11 Gene

  • Protein details for GPATCH11 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    G patch domain-containing protein 11
    Protein Accession:
    Secondary Accessions:
    • A8K0D9
    • B7Z2G4
    • B8ZZ44

    Protein attributes for GPATCH11 Gene

    259 amino acids
    Molecular mass:
    30199 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAH11850.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for GPATCH11 Gene


neXtProt entry for GPATCH11 Gene

Proteomics data for GPATCH11 Gene at MOPED

Post-translational modifications for GPATCH11 Gene

  • Ubiquitination at Lys 72
  • Modification sites at PhosphoSitePlus

Other Protein References for GPATCH11 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GPATCH11 Gene

Domains & Families for GPATCH11 Gene

Gene Families for GPATCH11 Gene

Protein Domains for GPATCH11 Gene


Suggested Antigen Peptide Sequences for GPATCH11 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 G-patch domain.
  • Belongs to the GPATCH11 family.
  • Contains 1 G-patch domain.
  • Belongs to the GPATCH11 family.
genes like me logo Genes that share domains with GPATCH11: view

Function for GPATCH11 Gene

Gene Ontology (GO) - Molecular Function for GPATCH11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with GPATCH11: view

Phenotypes for GPATCH11 Gene

genes like me logo Genes that share phenotypes with GPATCH11: view

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for GPATCH11

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for GPATCH11 Gene

Localization for GPATCH11 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for GPATCH11 Gene

Pathways & Interactions for GPATCH11 Gene

SuperPathways for GPATCH11 Gene

No Data Available

Gene Ontology (GO) - Biological Process for GPATCH11 Gene


No data available for Pathways by source and SIGNOR curated interactions for GPATCH11 Gene

Drugs & Compounds for GPATCH11 Gene

No Compound Related Data Available

Transcripts for GPATCH11 Gene

mRNA/cDNA for GPATCH11 Gene

Unigene Clusters for GPATCH11 Gene

G patch domain containing 11:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for GPATCH11

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for GPATCH11 Gene

No ASD Table

Relevant External Links for GPATCH11 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for GPATCH11 Gene

mRNA expression in normal human tissues for GPATCH11 Gene

Protein differential expression in normal tissues from HIPED for GPATCH11 Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (57.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for GPATCH11 Gene

SOURCE GeneReport for Unigene cluster for GPATCH11 Gene Hs.595250

genes like me logo Genes that share expression patterns with GPATCH11: view

Protein tissue co-expression partners for GPATCH11 Gene

- Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for GPATCH11 Gene

Orthologs for GPATCH11 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for GPATCH11 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia GPATCH11 35
  • 91.25 (n)
  • 93.92 (a)
  • 94 (a)
(Canis familiaris)
Mammalia GPATCH11 35
  • 90.84 (n)
  • 93.13 (a)
  • 86 (a)
(Mus musculus)
Mammalia Gpatch11 35
  • 84.79 (n)
  • 89.35 (a)
Gpatch11 16
Gpatch11 36
  • 88 (a)
(Pan troglodytes)
Mammalia CCDC75 35
  • 99.18 (n)
  • 98.25 (a)
CCDC75 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Gpatch11 35
  • 83.91 (n)
  • 89.96 (a)
(Monodelphis domestica)
Mammalia GPATCH11 36
  • 79 (a)
(Ornithorhynchus anatinus)
Mammalia GPATCH11 36
  • 79 (a)
(Gallus gallus)
Aves CCDC75 35
  • 72.78 (n)
  • 73.31 (a)
CCDC75 36
  • 73 (a)
(Anolis carolinensis)
Reptilia GPATCH11 36
  • 55 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia gpatch11 35
  • 66.93 (n)
  • 63.42 (a)
(Danio rerio)
Actinopterygii gpatch11 35
  • 57.46 (n)
  • 56.03 (a)
gpatch11 36
  • 57 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG10053 35
  • 47.41 (n)
  • 39.84 (a)
CG10053 36
  • 35 (a)
(Caenorhabditis elegans)
Secernentea CELE_T04H1.5 35
  • 48.83 (n)
  • 33.2 (a)
T04H1.5 36
  • 29 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT3G57910 35
  • 49.15 (n)
  • 36.22 (a)
(Oryza sativa)
Liliopsida Os08g0509500 35
  • 41.7 (n)
  • 33.18 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 37 (a)
Species with no ortholog for GPATCH11:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for GPATCH11 Gene

Gene Tree for GPATCH11 (if available)
Gene Tree for GPATCH11 (if available)

Paralogs for GPATCH11 Gene Pseudogenes for GPATCH11 Gene

genes like me logo Genes that share paralogs with GPATCH11: view

No data available for Paralogs for GPATCH11 Gene

Variants for GPATCH11 Gene

Sequence variations from dbSNP and Humsavar for GPATCH11 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs12871 -- 37,099,261(+) TTTAA(C/T)TGTTG downstream-variant-500B
rs1044549 -- 37,099,439(+) ATGAA(A/G)AAAAG downstream-variant-500B
rs1044559 -- 37,099,240(+) TCAAG(G/T)GTTAT utr-variant-3-prime
rs1060957 -- 37,098,637(+) ATAAC(A/G)CTGAT utr-variant-3-prime
rs3856498 -- 37,088,785(+) CCAAA(A/G)TGCTA intron-variant

Variation tolerance for GPATCH11 Gene

Residual Variation Intolerance Score: 72.17% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.61; 45.21% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for GPATCH11 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for GPATCH11 Gene

Disorders for GPATCH11 Gene

Relevant External Links for GPATCH11

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with GPATCH11: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GPATCH11 Gene

Publications for GPATCH11 Gene

  1. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  3. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 67
  4. Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph. (PMID: 21048031) Casabonne D. … de Sanjose S. (Haematologica 2011) 67
  5. Initial characterization of the human central proteome. (PMID: 21269460) Burkard T.R. … Colinge J. (BMC Syst. Biol. 2011) 67

Products for GPATCH11 Gene

Sources for GPATCH11 Gene

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