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Aliases for GPATCH11 Gene

Aliases for GPATCH11 Gene

  • G-Patch Domain Containing 11 2 3 5
  • Coiled-Coil Domain-Containing Protein 75 3 4
  • Coiled-Coil Domain Containing 75 2 3
  • Centromere Protein Y 2 3
  • CCDC75 3 4
  • G Patch Domain-Containing Protein 11 3
  • G Patch Domain Containing 11 3
  • CENP-Y 3
  • CENPY 3

External Ids for GPATCH11 Gene

Previous HGNC Symbols for GPATCH11 Gene

  • CCDC75

Previous GeneCards Identifiers for GPATCH11 Gene

  • GC02P037314

Summaries for GPATCH11 Gene

GeneCards Summary for GPATCH11 Gene

GPATCH11 (G-Patch Domain Containing 11) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GPATCH11 Gene

Genomics for GPATCH11 Gene

Regulatory Elements for GPATCH11 Gene

Enhancers for GPATCH11 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around GPATCH11 on UCSC Golden Path with GeneCards custom track

Promoters for GPATCH11 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around GPATCH11 on UCSC Golden Path with GeneCards custom track

Genomic Location for GPATCH11 Gene

Chromosome:
2
Start:
37,084,451 bp from pter
End:
37,099,244 bp from pter
Size:
14,794 bases
Orientation:
Plus strand

Genomic View for GPATCH11 Gene

Genes around GPATCH11 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GPATCH11 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GPATCH11 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GPATCH11 Gene

Proteins for GPATCH11 Gene

  • Protein details for GPATCH11 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8N954-GPT11_HUMAN
    Recommended name:
    G patch domain-containing protein 11
    Protein Accession:
    Q8N954
    Secondary Accessions:
    • A8K0D9
    • B7Z2G4
    • B8ZZ44

    Protein attributes for GPATCH11 Gene

    Size:
    259 amino acids
    Molecular mass:
    30199 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAH11850.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for GPATCH11 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for GPATCH11 Gene

Proteomics data for GPATCH11 Gene at MOPED

Post-translational modifications for GPATCH11 Gene

  • Ubiquitination at Lys 72
  • Modification sites at PhosphoSitePlus

Other Protein References for GPATCH11 Gene

No data available for DME Specific Peptides for GPATCH11 Gene

Domains & Families for GPATCH11 Gene

Gene Families for GPATCH11 Gene

Protein Domains for GPATCH11 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for GPATCH11 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8N954

UniProtKB/Swiss-Prot:

GPT11_HUMAN :
  • Contains 1 G-patch domain.
  • Belongs to the GPATCH11 family.
Domain:
  • Contains 1 G-patch domain.
Family:
  • Belongs to the GPATCH11 family.
genes like me logo Genes that share domains with GPATCH11: view

Function for GPATCH11 Gene

Gene Ontology (GO) - Molecular Function for GPATCH11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
genes like me logo Genes that share ontologies with GPATCH11: view
genes like me logo Genes that share phenotypes with GPATCH11: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GPATCH11 Gene

Localization for GPATCH11 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for GPATCH11 Gene

Pathways & Interactions for GPATCH11 Gene

SuperPathways for GPATCH11 Gene

No Data Available

Gene Ontology (GO) - Biological Process for GPATCH11 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GPATCH11 Gene

Drugs & Compounds for GPATCH11 Gene

No Compound Related Data Available

Transcripts for GPATCH11 Gene

Unigene Clusters for GPATCH11 Gene

G patch domain containing 11:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for GPATCH11 Gene

No ASD Table

Relevant External Links for GPATCH11 Gene

GeneLoc Exon Structure for
GPATCH11
ECgene alternative splicing isoforms for
GPATCH11

Expression for GPATCH11 Gene

mRNA expression in normal human tissues for GPATCH11 Gene

Protein differential expression in normal tissues from HIPED for GPATCH11 Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (57.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for GPATCH11 Gene



SOURCE GeneReport for Unigene cluster for GPATCH11 Gene Hs.595250

genes like me logo Genes that share expression patterns with GPATCH11: view

Protein tissue co-expression partners for GPATCH11 Gene

- Elite partner

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for GPATCH11 Gene

Orthologs for GPATCH11 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for GPATCH11 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia GPATCH11 35
  • 91.25 (n)
  • 93.92 (a)
GPATCH11 36
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia GPATCH11 35
  • 90.84 (n)
  • 93.13 (a)
GPATCH11 36
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gpatch11 35
  • 84.79 (n)
  • 89.35 (a)
Gpatch11 16
Gpatch11 36
  • 88 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia CCDC75 35
  • 99.18 (n)
  • 98.25 (a)
CCDC75 36
  • 99 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Gpatch11 35
  • 83.91 (n)
  • 89.96 (a)
oppossum
(Monodelphis domestica)
Mammalia GPATCH11 36
  • 79 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia GPATCH11 36
  • 79 (a)
OneToOne
chicken
(Gallus gallus)
Aves CCDC75 35
  • 72.78 (n)
  • 73.31 (a)
CCDC75 36
  • 73 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia GPATCH11 36
  • 55 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia gpatch11 35
  • 66.93 (n)
  • 63.42 (a)
zebrafish
(Danio rerio)
Actinopterygii gpatch11 35
  • 57.46 (n)
  • 56.03 (a)
gpatch11 36
  • 57 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG10053 35
  • 47.41 (n)
  • 39.84 (a)
CG10053 36
  • 35 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea CELE_T04H1.5 35
  • 48.83 (n)
  • 33.2 (a)
T04H1.5 36
  • 29 (a)
OneToOne
thale cress
(Arabidopsis thaliana)
eudicotyledons AT3G57910 35
  • 49.15 (n)
  • 36.22 (a)
rice
(Oryza sativa)
Liliopsida Os08g0509500 35
  • 41.7 (n)
  • 33.18 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 37 (a)
OneToOne
Species with no ortholog for GPATCH11:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for GPATCH11 Gene

ENSEMBL:
Gene Tree for GPATCH11 (if available)
TreeFam:
Gene Tree for GPATCH11 (if available)

Paralogs for GPATCH11 Gene

Pseudogenes.org Pseudogenes for GPATCH11 Gene

genes like me logo Genes that share paralogs with GPATCH11: view

No data available for Paralogs for GPATCH11 Gene

Variants for GPATCH11 Gene

Sequence variations from dbSNP and Humsavar for GPATCH11 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1044549 -- 37,099,439(+) ATGAA(A/G)AAAAG downstream-variant-500B
rs1044559 -- 37,099,240(+) TCAAG(G/T)GTTAT utr-variant-3-prime
rs1060957 -- 37,098,637(+) ATAAC(A/G)CTGAT utr-variant-3-prime
rs3856498 -- 37,088,785(+) CCAAA(A/G)TGCTA intron-variant
rs3856499 -- 37,097,965(+) ATGTG(C/T)ATATA utr-variant-3-prime

Variation tolerance for GPATCH11 Gene

Residual Variation Intolerance Score: 72.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.61; 45.21% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for GPATCH11 Gene

Disorders for GPATCH11 Gene

Relevant External Links for GPATCH11

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
GPATCH11

No disorders were found for GPATCH11 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GPATCH11 Gene

Publications for GPATCH11 Gene

  1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover. (PMID: 24999758) Elzi D.J. … Shiio Y. (J. Proteome Res. 2014) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. (PMID: 22658674) Castello A. … Hentze M.W. (Cell 2012) 3

Products for GPATCH11 Gene

Sources for GPATCH11 Gene

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