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Aliases for GPATCH11 Gene

Aliases for GPATCH11 Gene

  • G-Patch Domain Containing 11 2 3 5
  • Coiled-Coil Domain-Containing Protein 75 3 4
  • Coiled-Coil Domain Containing 75 2 3
  • Centromere Protein Y 2 3
  • CCDC75 3 4
  • CENP-Y 3 4
  • G Patch Domain-Containing Protein 11 3
  • CENPY 3

External Ids for GPATCH11 Gene

Previous HGNC Symbols for GPATCH11 Gene

  • CCDC75

Previous GeneCards Identifiers for GPATCH11 Gene

  • GC02P037314

Summaries for GPATCH11 Gene

GeneCards Summary for GPATCH11 Gene

GPATCH11 (G-Patch Domain Containing 11) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GPATCH11 Gene

Genomics for GPATCH11 Gene

Regulatory Elements for GPATCH11 Gene

Enhancers for GPATCH11 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02F037098 1 ENCODE 11.7 +14.4 14420 1.7 ATF1 PKNOX1 CREB3L1 SIN3A ZNF2 YY1 GLIS2 ZNF143 ZNF263 SP3 GPATCH11 EIF2AK2 HEATR5B CEBPZOS ENSG00000224891
GH02F036961 1.4 Ensembl ENCODE 5.5 -119.2 -119239 7.3 HDGF PKNOX1 ARNT CREB3L1 WRNIP1 ARID4B SIN3A DMAP1 ZNF2 YY1 CEBPZ STRN PRKD3 GPATCH11 GC02P036908
GH02F037079 0.6 ENCODE 12.5 -3.8 -3787 2.6 HDAC1 PKNOX1 KLF1 TBX21 SPI1 ZBTB17 GPATCH11 CEBPZOS HEATR5B GC02M036982
GH02F037110 0.4 ENCODE 13 +26.5 26512 0.1 CEBPB EMSY GPATCH11 HEATR5B ENSG00000224891
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around GPATCH11 on UCSC Golden Path with GeneCards custom track

Genomic Location for GPATCH11 Gene

37,084,451 bp from pter
37,099,244 bp from pter
14,794 bases
Plus strand

Genomic View for GPATCH11 Gene

Genes around GPATCH11 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GPATCH11 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GPATCH11 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GPATCH11 Gene

Proteins for GPATCH11 Gene

  • Protein details for GPATCH11 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    G patch domain-containing protein 11
    Protein Accession:
    Secondary Accessions:
    • A8K0D9
    • B7Z2G4
    • B8ZZ44

    Protein attributes for GPATCH11 Gene

    259 amino acids
    Molecular mass:
    30199 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAH11850.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for GPATCH11 Gene


neXtProt entry for GPATCH11 Gene

Post-translational modifications for GPATCH11 Gene

  • Ubiquitination at Lys 72
  • Modification sites at PhosphoSitePlus

Other Protein References for GPATCH11 Gene

No data available for DME Specific Peptides for GPATCH11 Gene

Domains & Families for GPATCH11 Gene

Gene Families for GPATCH11 Gene

Protein Domains for GPATCH11 Gene


Suggested Antigen Peptide Sequences for GPATCH11 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 G-patch domain.
  • Belongs to the GPATCH11 family.
  • Contains 1 G-patch domain.
  • Belongs to the GPATCH11 family.
genes like me logo Genes that share domains with GPATCH11: view

Function for GPATCH11 Gene

Gene Ontology (GO) - Molecular Function for GPATCH11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with GPATCH11: view
genes like me logo Genes that share phenotypes with GPATCH11: view

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GPATCH11 Gene

Localization for GPATCH11 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GPATCH11 Gene

Chromosome, centromere, kinetochore.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GPATCH11 gene
Compartment Confidence
nucleus 4
cytosol 4
cytoskeleton 2

Gene Ontology (GO) - Cellular Components for GPATCH11 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000776 kinetochore IEA,IDA 20813266
GO:0000777 condensed chromosome kinetochore IEA --
GO:0005694 chromosome IEA --
genes like me logo Genes that share ontologies with GPATCH11: view

Pathways & Interactions for GPATCH11 Gene

SuperPathways for GPATCH11 Gene

No Data Available

Gene Ontology (GO) - Biological Process for GPATCH11 Gene


No data available for Pathways by source and SIGNOR curated interactions for GPATCH11 Gene

Transcripts for GPATCH11 Gene

Unigene Clusters for GPATCH11 Gene

G patch domain containing 11:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for GPATCH11 Gene

No ASD Table

Relevant External Links for GPATCH11 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for GPATCH11 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for GPATCH11 Gene

Protein differential expression in normal tissues from HIPED for GPATCH11 Gene

This gene is overexpressed in Bone marrow mesenchymal stem cell (57.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for GPATCH11 Gene

Protein tissue co-expression partners for GPATCH11 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of GPATCH11 Gene:


SOURCE GeneReport for Unigene cluster for GPATCH11 Gene:

genes like me logo Genes that share expression patterns with GPATCH11: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for GPATCH11 Gene

Orthologs for GPATCH11 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for GPATCH11 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia CCDC75 34 35
  • 99.18 (n)
(Bos Taurus)
Mammalia GPATCH11 34 35
  • 91.25 (n)
(Canis familiaris)
Mammalia GPATCH11 34 35
  • 90.84 (n)
(Mus musculus)
Mammalia Gpatch11 34 16 35
  • 84.79 (n)
(Rattus norvegicus)
Mammalia Gpatch11 34
  • 83.91 (n)
(Monodelphis domestica)
Mammalia GPATCH11 35
  • 79 (a)
(Ornithorhynchus anatinus)
Mammalia GPATCH11 35
  • 79 (a)
(Gallus gallus)
Aves CCDC75 34 35
  • 72.78 (n)
(Anolis carolinensis)
Reptilia GPATCH11 35
  • 55 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia gpatch11 34
  • 66.93 (n)
(Danio rerio)
Actinopterygii gpatch11 34 35
  • 57.46 (n)
fruit fly
(Drosophila melanogaster)
Insecta CG10053 34 35
  • 47.41 (n)
(Caenorhabditis elegans)
Secernentea CELE_T04H1.5 34
  • 48.83 (n)
T04H1.5 35
  • 29 (a)
thale cress
(Arabidopsis thaliana)
eudicotyledons AT3G57910 34
  • 49.15 (n)
(Oryza sativa)
Liliopsida Os08g0509500 34
  • 41.7 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 37 (a)
Species where no ortholog for GPATCH11 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for GPATCH11 Gene

Gene Tree for GPATCH11 (if available)
Gene Tree for GPATCH11 (if available)

Paralogs for GPATCH11 Gene Pseudogenes for GPATCH11 Gene

genes like me logo Genes that share paralogs with GPATCH11: view

No data available for Paralogs for GPATCH11 Gene

Variants for GPATCH11 Gene

Sequence variations from dbSNP and Humsavar for GPATCH11 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs10153588 -- 37,095,770(+) TGAGA(A/G)TGATG intron-variant
rs10176233 -- 37,084,350(+) CCGCA(C/G)TCCTA upstream-variant-2KB, utr-variant-5-prime
rs10176303 -- 37,084,272(+) ACCTC(C/G)TAGTC nc-transcript-variant, upstream-variant-2KB, utr-variant-5-prime
rs10188586 -- 37,084,196(+) ATGTC(C/T)TCCCC intron-variant, nc-transcript-variant, upstream-variant-2KB, utr-variant-5-prime
rs10194972 -- 37,085,936(+) gtttg(C/T)gctgg intron-variant, upstream-variant-2KB

Variation tolerance for GPATCH11 Gene

Residual Variation Intolerance Score: 72.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.61; 45.21% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for GPATCH11 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for GPATCH11 Gene

Disorders for GPATCH11 Gene

Relevant External Links for GPATCH11

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for GPATCH11 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GPATCH11 Gene

Publications for GPATCH11 Gene

  1. The protein composition of mitotic chromosomes determined using multiclassifier combinatorial proteomics. (PMID: 20813266) Ohta S. … Rappsilber J. (Cell 2010) 3 4 64
  2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4 64
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  5. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64

Products for GPATCH11 Gene

Sources for GPATCH11 Gene

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