Free for academic non-profit institutions. Other users need a Commercial license

Aliases for GPANK1 Gene

Aliases for GPANK1 Gene

  • G Patch Domain And Ankyrin Repeats 1 2 3
  • BAT4 3 4 6
  • Ankyrin Repeat Domain-Containing Protein 59 3 4
  • G Patch Domain-Containing Protein 10 3 4
  • HLA-B-Associated Transcript 4 3 4
  • G Patch Domain Containing 10 2 3
  • Protein G5 3 4
  • GPATCH10 3 4
  • ANKRD59 3 4
  • D6S54E 3 6
  • G5 3 4
  • G Patch Domain And Ankyrin Repeats-Containing Protein 1 3
  • G Patch Domain And Ankyrin Repeat-Containing Protein 1 3
  • HLA-B Associated Transcript 4 2
  • Ankyrin Repeat Domain 59 2
  • Protein BAT4 3

External Ids for GPANK1 Gene

Previous HGNC Symbols for GPANK1 Gene

  • BAT4

Previous GeneCards Identifiers for GPANK1 Gene

  • GC06M031417
  • GC06M031631
  • GC06M031635
  • GC06M031638
  • GC06M031642
  • GC06M031647
  • GC06M031651
  • GC06M031695

Summaries for GPANK1 Gene

Entrez Gene Summary for GPANK1 Gene

  • This gene is located in a cluster of HLA-B-associated transcripts, which is included in the human major histocompatability complex III region. This gene encodes a protein which is thought to play a role in immunity. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2010]

GeneCards Summary for GPANK1 Gene

GPANK1 (G Patch Domain And Ankyrin Repeats 1) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding.

Gene Wiki entry for GPANK1 Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GPANK1 Gene

Genomics for GPANK1 Gene

Genomic Location for GPANK1 Gene

Start:
31,661,229 bp from pter
End:
31,666,283 bp from pter
Size:
5,055 bases
Orientation:
Minus strand

Genomic View for GPANK1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for GPANK1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

No data available for Regulatory Elements for GPANK1 Gene

Proteins for GPANK1 Gene

  • Protein details for GPANK1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O95872-GPAN1_HUMAN
    Recommended name:
    G patch domain and ankyrin repeat-containing protein 1
    Protein Accession:
    O95872
    Secondary Accessions:
    • A6NG25
    • B0UXA2
    • Q5SQ49

    Protein attributes for GPANK1 Gene

    Size:
    356 amino acids
    Molecular mass:
    39314 Da
    Quaternary structure:
    No Data Available

neXtProt entry for GPANK1 Gene

Proteomics data for GPANK1 Gene at MOPED

Post-translational modifications for GPANK1 Gene

  • Ubiquitination at Lys103 and Lys261
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for GPANK1 Gene

Domains for GPANK1 Gene

Gene Families for GPANK1 Gene

HGNC:
  • ANKRD :Ankyrin repeat domain containing
  • GPATCH :G patch domain containing

Protein Domains for GPANK1 Gene

Suggested Antigen Peptide Sequences for GPANK1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O95872

UniProtKB/Swiss-Prot:

GPAN1_HUMAN :
  • O95872
Domain:
  • Contains 1 G-patch domain.
Similarity:
  • Contains 2 ANK repeats.
genes like me logo Genes that share domains with GPANK1: view

Function for GPANK1 Gene

Gene Ontology (GO) - Molecular Function for GPANK1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003676 nucleic acid binding IEA --
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with GPANK1: view

Phenotypes for GPANK1 Gene

GenomeRNAi human phenotypes for GPANK1:
genes like me logo Genes that share phenotypes with GPANK1: view

miRNA for GPANK1 Gene

miRTarBase miRNAs that target GPANK1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for GPANK1 Gene

Localization for GPANK1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for GPANK1 Gene

Pathways for GPANK1 Gene

SuperPathways for GPANK1 Gene

No Data Available

Interacting Proteins for GPANK1 Gene

Gene Ontology (GO) - Biological Process for GPANK1 Gene

None

No data available for Pathways by source for GPANK1 Gene

Transcripts for GPANK1 Gene

Unigene Clusters for GPANK1 Gene

G patch domain and ankyrin repeats 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for GPANK1 Gene

No ASD Table

Relevant External Links for GPANK1 Gene

GeneLoc Exon Structure for
GPANK1
ECgene alternative splicing isoforms for
GPANK1

Expression for GPANK1 Gene

mRNA expression in normal human tissues for GPANK1 Gene

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for GPANK1 Gene

SOURCE GeneReport for Unigene cluster for GPANK1 Gene Hs.247478

genes like me logo Genes that share expressions with GPANK1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for GPANK1 Gene

Orthologs for GPANK1 Gene

This gene was present in the common ancestor of animals.

Orthologs for GPANK1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia GPANK1 35
  • 99.72 (n)
  • 99.16 (a)
GPANK1 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia BAT4 36
  • 83 (a)
OneToOne
GPANK1 35
  • 84.62 (n)
  • 83.48 (a)
dog
(Canis familiaris)
Mammalia GPANK1 35
  • 85.09 (n)
  • 85.19 (a)
GPANK1 36
  • 85 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gpank1 35
  • 80.6 (n)
  • 80.98 (a)
Gpank1 16
Gpank1 36
  • 76 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia GPANK1 36
  • 63 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Gpank1 35
  • 81.03 (n)
  • 81.32 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia gpank1 35
  • 48.51 (n)
  • 42.26 (a)
zebrafish
(Danio rerio)
Actinopterygii GPANK1 36
  • 39 (a)
OneToOne
zgc:171777 35
  • 49.59 (n)
  • 41.46 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG8152 35
  • 44.93 (n)
  • 34.8 (a)
CG8152 36
  • 29 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea ZK1320.7 36
  • 23 (a)
OneToOne
Species with no ortholog for GPANK1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for GPANK1 Gene

ENSEMBL:
Gene Tree for GPANK1 (if available)
TreeFam:
Gene Tree for GPANK1 (if available)

Paralogs for GPANK1 Gene

No data available for Paralogs for GPANK1 Gene

Variants for GPANK1 Gene

Sequence variations from dbSNP and Humsavar for GPANK1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs805259 -- 31,663,600(-) agaat(C/T)GTTGT intron-variant
rs805260 -- 31,663,054(-) gctga(C/G/T)gcagg intron-variant
rs3117580 -- 31,663,191(-) GTCGC(C/T)CAGGC intron-variant
rs9281549 -- 31,662,948(+) ttttt(-/T)gagat intron-variant
rs12527318 -- 31,663,653(+) catta(A/G)gttgt intron-variant

Structural Variations from Database of Genomic Variants (DGV) for GPANK1 Gene

Variant ID Type Subtype PubMed ID
nsv830627 CNV Loss 17160897
nsv884418 CNV Gain 21882294
nsv462871 CNV Loss 19166990
dgv6581n71 CNV Loss 21882294

Relevant External Links for GPANK1 Gene

HapMap Linkage Disequilibrium report
GPANK1
Human Gene Mutation Database (HGMD)
GPANK1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GPANK1 Gene

Disorders for GPANK1 Gene

No disorders were found for GPANK1 Gene.

No data available for UniProtKB/Swiss-Prot for GPANK1 Gene

Publications for GPANK1 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Human major histocompatibility complex contains a minimum of 19 genes between the complement cluster and HLA-B. (PMID: 2813433) Spies T. … Strominger J.L. (Proc. Natl. Acad. Sci. U.S.A. 1989) 2 3
  3. A new cluster of genes within the human major histocompatibility complex. (PMID: 2911734) Spies T. … Strominger J.L. (Science 1989) 2 3
  4. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4
  5. Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse. (PMID: 14656967) Xie T. … Hood L. (Genome Res. 2003) 3 4

Products for GPANK1 Gene

Sources for GPANK1 Gene

Back to Top

Content