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Aliases for GPALPP1 Gene

Aliases for GPALPP1 Gene

  • GPALPP Motifs Containing 1 2 3 5
  • KIAA1704 2 3 4
  • Lipopolysaccharide-Specific Response Protein 7 3 4
  • LSR7 3 4
  • Lipopolysaccharide Specific Response-7 Protein 3
  • BA245H20.2 3
  • AD029 3

External Ids for GPALPP1 Gene

Previous HGNC Symbols for GPALPP1 Gene

  • KIAA1704

Previous GeneCards Identifiers for GPALPP1 Gene

  • GC13P045564

Summaries for GPALPP1 Gene

GeneCards Summary for GPALPP1 Gene

GPALPP1 (GPALPP Motifs Containing 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GPALPP1 Gene

Genomics for GPALPP1 Gene

Regulatory Elements for GPALPP1 Gene

Enhancers for GPALPP1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around GPALPP1 on UCSC Golden Path with GeneCards custom track

Promoters for GPALPP1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around GPALPP1 on UCSC Golden Path with GeneCards custom track

Genomic Location for GPALPP1 Gene

Chromosome:
13
Start:
44,989,529 bp from pter
End:
45,037,669 bp from pter
Size:
48,141 bases
Orientation:
Plus strand

Genomic View for GPALPP1 Gene

Genes around GPALPP1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GPALPP1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GPALPP1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GPALPP1 Gene

Proteins for GPALPP1 Gene

  • Protein details for GPALPP1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IXQ4-GPAM1_HUMAN
    Recommended name:
    GPALPP motifs-containing protein 1
    Protein Accession:
    Q8IXQ4
    Secondary Accessions:
    • A8K8X8
    • Q05BX8
    • Q05D87
    • Q5T3Z3
    • Q5T3Z5
    • Q9C0F9
    • Q9H2R0
    • Q9P0W6

    Protein attributes for GPALPP1 Gene

    Size:
    340 amino acids
    Molecular mass:
    38142 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH17776.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence.; Evidence={ECO:0000305}; Sequence=BAB21795.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Alternative splice isoforms for GPALPP1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for GPALPP1 Gene

Proteomics data for GPALPP1 Gene at MOPED

Post-translational modifications for GPALPP1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GPALPP1 Gene

No data available for DME Specific Peptides for GPALPP1 Gene

Domains & Families for GPALPP1 Gene

Protein Domains for GPALPP1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for GPALPP1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with GPALPP1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for GPALPP1 Gene

Function for GPALPP1 Gene

genes like me logo Genes that share phenotypes with GPALPP1: view

Animal Model Products

CRISPR Products

miRNA for GPALPP1 Gene

miRTarBase miRNAs that target GPALPP1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GPALPP1 Gene

Localization for GPALPP1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for GPALPP1 Gene

Pathways & Interactions for GPALPP1 Gene

SuperPathways for GPALPP1 Gene

No Data Available

Interacting Proteins for GPALPP1 Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000355211%0d%0a9606.ENSP00000260983%0d%0a9606.ENSP00000344818%0d%0a9606.ENSP00000303754%0d%0a
Selected Interacting proteins: ENSP00000355211 for GPALPP1 Gene via STRING

Gene Ontology (GO) - Biological Process for GPALPP1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GPALPP1 Gene

Drugs & Compounds for GPALPP1 Gene

No Compound Related Data Available

Transcripts for GPALPP1 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for GPALPP1 Gene

No ASD Table

Relevant External Links for GPALPP1 Gene

GeneLoc Exon Structure for
GPALPP1
ECgene alternative splicing isoforms for
GPALPP1

Expression for GPALPP1 Gene

mRNA expression in normal human tissues for GPALPP1 Gene

Protein differential expression in normal tissues from HIPED for GPALPP1 Gene

This gene is overexpressed in Liver, secretome (24.9), Peripheral blood mononuclear cells (8.7), and Blymphocyte (6.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for GPALPP1 Gene



genes like me logo Genes that share expression patterns with GPALPP1: view

Protein tissue co-expression partners for GPALPP1 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for GPALPP1 Gene

Orthologs for GPALPP1 Gene

This gene was present in the common ancestor of animals.

Orthologs for GPALPP1 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia GPALPP1 35
  • 91.18 (n)
  • 93.53 (a)
GPALPP1 36
  • 90 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gpalpp1 35
  • 89.28 (n)
  • 91.45 (a)
Gpalpp1 16
Gpalpp1 36
  • 90 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia GPALPP1 35
  • 99.8 (n)
  • 99.71 (a)
GPALPP1 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Gpalpp1 35
  • 86.18 (n)
  • 89.12 (a)
cow
(Bos Taurus)
Mammalia GPALPP1 36
  • 79 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia GPALPP1 36
  • 78 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia GPALPP1 36
  • 68 (a)
OneToOne
chicken
(Gallus gallus)
Aves GPALPP1 35
  • 70.8 (n)
  • 69.62 (a)
GPALPP1 36
  • 68 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia GPALPP1 36
  • 62 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia gpalpp1 35
  • 64.09 (n)
  • 62.5 (a)
Str.15378 35
African clawed frog
(Xenopus laevis)
Amphibia Xl.5217 35
zebrafish
(Danio rerio)
Actinopterygii gpalpp1 35
  • 61.41 (n)
  • 58.72 (a)
wufc50h08 35
gpalpp1 36
  • 45 (a)
OneToOne
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004241 35
  • 48.85 (n)
  • 41.38 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG33332 35
  • 47.62 (n)
  • 40.69 (a)
CG33332 36
  • 25 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea F26A3.7 35
  • 50.73 (n)
  • 39.51 (a)
F26A3.7 36
  • 33 (a)
OneToOne
Species with no ortholog for GPALPP1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for GPALPP1 Gene

ENSEMBL:
Gene Tree for GPALPP1 (if available)
TreeFam:
Gene Tree for GPALPP1 (if available)

Paralogs for GPALPP1 Gene

No data available for Paralogs for GPALPP1 Gene

Variants for GPALPP1 Gene

Sequence variations from dbSNP and Humsavar for GPALPP1 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type
rs13195 -- 45,033,314(-) GCTAT(A/C)TCCAA nc-transcript-variant, utr-variant-3-prime
rs13829 -- 45,031,612(+) CTTAC(G/T)GGCCT intron-variant
rs15742 -- 45,033,110(+) TGGTT(A/G)TTGTA intron-variant
rs1341262 -- 45,007,609(-) GAGCA(A/G)AACAA intron-variant, upstream-variant-2KB
rs2153652 -- 45,031,066(-) CAATT(A/C)TCCTG intron-variant

Variation tolerance for GPALPP1 Gene

Residual Variation Intolerance Score: 74.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.11; 38.41% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for GPALPP1 Gene

HapMap Linkage Disequilibrium report
GPALPP1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for GPALPP1 Gene

Disorders for GPALPP1 Gene

Relevant External Links for GPALPP1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
GPALPP1

No disorders were found for GPALPP1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GPALPP1 Gene

Publications for GPALPP1 Gene

  1. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11214970) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4 67
  2. Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes. (PMID: 25281560) Lambert J.P. … Gingras A.C. (J Proteomics 2015) 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  5. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. (PMID: 26673895) KA+rlA+ K. … GAPrlich D. (Elife 2015) 3

Products for GPALPP1 Gene

Sources for GPALPP1 Gene

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