Aliases for GP6 Gene
Aliases for GP6 Gene
External Ids for GP6 Gene
- HGNC: 14388
- Entrez Gene: 51206
- Ensembl: ENSG00000088053
- OMIM: 605546
- UniProtKB: Q9HCN6
Previous GeneCards Identifiers for GP6 Gene
- GC19M056387
- GC19M055949
- GC19M060201
- GC19M060216
- GC19M055525
- GC19M051846
Summaries for GP6 Gene
-
This gene encodes a platelet membrane glycoprotein of the immunoglobulin superfamily. The encoded protein is a receptor for collagen and plays a critical role in collagen-induced platelet aggregation and thrombus formation. The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding. Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
GeneCards Summary for GP6 Gene
GP6 (Glycoprotein VI Platelet) is a Protein Coding gene. Diseases associated with GP6 include Bleeding Disorder, Platelet-Type, 11 and Cervical Adenosarcoma. Among its related pathways are G beta-gamma signalling through PI3Kgamma and Response to elevated platelet cytosolic Ca2+. GO annotations related to this gene include receptor activity and collagen binding. An important paralog of this gene is LILRB1.
UniProtKB/Swiss-Prot for GP6 Gene
-
Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely Fyn/Lyn), the adapter protein LAT and leads to the activation of phospholipase C gamma2.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GP6 Gene
Genomics for GP6 Gene
Regulatory Elements for GP6 Gene
Enhancers for GP6 Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around GP6 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the GP6 gene promoter:
Regulatory Element Products
Genomic Location for GP6 Gene
- Chromosome:
- 19
- Start:
- 55,013,705 bp from pter
- End:
- 55,038,264 bp from pter
- Size:
- 24,560 bases
- Orientation:
- Minus strand
Genomic View for GP6 Gene
Genes around GP6 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 19q13.42 by Ensembl
- 19q13.42 by Entrez Gene
- 19q13.42 by HGNC
GP6 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for GP6 Gene
Proteins for GP6 Gene
-
Protein details for GP6 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9HCN6-GPVI_HUMAN
- Recommended name:
- Platelet glycoprotein VI
- Protein Accession:
- Q9HCN6
- Q9HCN7
- Q9UIF2
Protein attributes for GP6 Gene
- Size:
- 339 amino acids
- Molecular mass:
- 36866 Da
- Quaternary structure:
-
- Associated with Fc receptor gamma chain. The GPVI-FcRgamma complex is associated with the Src kinase family Fyn and Lyn.
Protein Expression for GP6 Gene
Post-translational modifications for GP6 Gene
- N-linked glycosylation at Asn-92 is not required for the cell surface expression, but contributes to maximal adhesion to type I collagen, collagen-related peptide (CRP), and, to a lesser extent, to the snake venom C-type lectin convulxin (CVX).
- Glycosylation at isoforms=2, 392
Other Protein References for GP6 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for GP6
- R&D Systems Antibodies for GP6 (GPVI)
- Novus Biologicals Antibodies for GP6
-
Abcam antibodies for GP6
-
Cloud-Clone Corp. Antibodies for GP6
- Invitrogen Antibodies for GP6
- antibodies-online Antibodies for GP6: See all 66
- GeneTex GP6 antibody for GP6
-
Custom Antibody ServicesProSci Antibodies for GP6
-
Santa Cruz Biotechnology (SCBT) Antibodies for GP6
Protein Products
- R&D Systems Proteins and Enzymes for GP6 (GPVI)
-
OriGene Purified Proteins for GP6
- Search Origene for MassSpec and Protein Over-expression Lysates for GP6
- Origene Custom Protein Services for GP6
-
Cloud-Clone Corp. Proteins for GP6
- antibodies-online Proteins for GP6: See all 5
- Search antibodies-online for peptides
- Search GeneTex for Proteins for GP6
No data available for DME Specific Peptides for GP6 Gene
Domains & Families for GP6 Gene
Gene Families for GP6 Gene
Protein Domains for GP6 Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for GP6 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for GP6 Gene
Function for GP6 Gene
Molecular function for GP6 Gene
- UniProtKB/Swiss-Prot Function:
- Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely Fyn/Lyn), the adapter protein LAT and leads to the activation of phospholipase C gamma2.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004872 | receptor activity | TAS | 11027634 |
| GO:0004888 | transmembrane signaling receptor activity | TAS | 10822077 |
| GO:0005515 | protein binding | IPI | 1715582 |
| GO:0005518 | collagen binding | TAS | 11027634 |
Phenotypes for GP6 Gene
- MGI mutant phenotypes for GP6:
- inferred from 4 alleles
- GenomeRNAi human phenotypes for GP6:
Animal Model Products
-
Taconic Biosciences Mouse Models for GP6
- Cyagen custom Knockout/knockin (KOKI) mouse models for GP6
-
-
ViGene Biosciences lentiviral particle packaged cDNA for GP6 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for GP6 gene
- Search ViGene Biosciences for GP6
CRISPR Products
-
OriGene CRISPR knockouts for GP6
-
Santa Cruz Biotechnology (SCBT) CRISPR for GP6
- GenScript: Design CRISPR guide RNA sequences for GP6
miRNA Products
- Search ViGene Biosciences for GP6
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for GP6
- Browse OriGene Inhibitory RNA Products For GP6
-
ViGene Biosciences ready-to-package AAV shRNAs for GP6 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for GP6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for GP6
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- R&D Systems cDNA Clones for GP6 (GPVI)
Cell Line Products
-
Horizon Cell Lines for GP6
-
ViGene Biosciences adenoviral particle packaged cDNA for GP6 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for GP6 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for GP6 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , miRNA , Transcription Factor Targets and HOMER Transcription for GP6 Gene
Localization for GP6 Gene
Subcellular locations from UniProtKB/Swiss-Prot for GP6 Gene
- Isoform 1: Cell membrane; Single-pass membrane protein.
- Isoform 2: Cell membrane; Single-pass membrane protein.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 5 |
| cytosol | 2 |
| cytoskeleton | 1 |
| mitochondrion | 1 |
| lysosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0005887 | integral component of plasma membrane | TAS | 10822077 |
| GO:0009986 | cell surface | IDA | 23382103 |
| GO:0016020 | membrane | IEA | -- |
| GO:0016021 | integral component of membrane | IEA | -- |
Pathways & Interactions for GP6 Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Response to elevated platelet cytosolic Ca2+ |
.44
|
|
| 2 | ECM-receptor interaction | ||
| 3 | Platelet activation | ||
| 4 | Platelet Aggregation Inhibitor Pathway, Pharmacodynamics | ||
| 5 | Formation of Fibrin Clot (Clotting Cascade) | ||
Pathways by source for GP6 Gene
5 Reactome pathways for GP6 Gene
1 PharmGKB pathway for GP6 Gene
2 KEGG pathways for GP6 Gene
1 R&D Systems pathway for GP6 Gene
Interacting Proteins for GP6 Gene
Selected Interacting proteins:
Q9HCN6-GPVI_HUMAN
ENSP00000308782
for GP6 Gene via
MINT
STRING
IID
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007167 | enzyme linked receptor protein signaling pathway | TAS | 9153205 |
| GO:0007596 | blood coagulation | TAS | -- |
| GO:0007599 | hemostasis | IEA | -- |
| GO:0030168 | platelet activation | TAS | -- |
| GO:0050900 | leukocyte migration | TAS | -- |
No data available for SIGNOR curated interactions for GP6 Gene
Transcripts for GP6 Gene
mRNA/cDNA for GP6 Gene
- (3) REFSEQ mRNAs :
- (7) Additional mRNA sequences :
- (29) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for GP6 Gene
- Glycoprotein VI (platelet):
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for GP6
-
Santa Cruz Biotechnology (SCBT) CRISPR for GP6
- GenScript: Design CRISPR guide RNA sequences for GP6
miRNA Products
- Search ViGene Biosciences for GP6
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for GP6
- Browse OriGene Inhibitory RNA Products For GP6
-
ViGene Biosciences ready-to-package AAV shRNAs for GP6 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for GP6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for GP6
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- R&D Systems cDNA Clones for GP6 (GPVI)
Flow Cytometry Products
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7a | · | 7b |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||||||||||
| SP2: | - | ||||||||||||||||
| SP3: |
Expression for GP6 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Brain (Nervous System)
- Mature Endothelial Cells Blood Brain Barrier
-
Endothelium (Cardiovascular System)
- Mature Endothelial Cells Blood Brain Barrier
mRNA differential expression in normal tissues according to GTEx for GP6 Gene
This gene is overexpressed in Whole Blood (x5.6) and Testis (x4.2).
This gene is overexpressed in Peripheral blood mononuclear cells (24.3), Serum (20.1), and Platelet (14.3).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for GP6 Gene
NURSA nuclear receptor signaling pathways regulating expression of GP6 Gene:
GP6SOURCE GeneReport for Unigene cluster for GP6 Gene:
Hs.661752mRNA Expression by UniProt/SwissProt for GP6 Gene:
Q9HCN6-GPVI_HUMAN
Tissue specificity:
Megakaryocytes and platelets.
Evidence on tissue expression from TISSUES for GP6 Gene
- Blood(4.6)
Phenotype-based relationships between genes and organs from Gene ORGANizer for GP6 Gene
Germ Layers:
- ectoderm
- mesoderm
Systems:
- cardiovascular
- integumentary
- nervous
- reproductive
Organs:
Head and neck:
- brain
- face
- head
- nose
Pelvis:
- uterus
General:
- blood
- blood vessel
- coagulation system
- skin
Primer Products
-
OriGene qPCR primer pairs for GP6
-
OriGene qPCR primer pairs and template standards for GP6
Orthologs for GP6 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | GP6 34 35 |
|
||
| dog (Canis familiaris) |
Mammalia | GP6 35 34 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Gp6 34 16 35 |
|
||
| cow (Bos Taurus) |
Mammalia | GP6 35 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Gp6 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
OneToMany | |
| -- 35 |
|
OneToMany | |||
| -- 35 |
|
OneToMany | |||
| -- 35 |
|
OneToMany | |||
| -- 35 |
|
OneToMany | |||
| -- 35 |
|
OneToMany | |||
| -- 35 |
|
OneToMany | |||
| -- 35 |
|
OneToMany | |||
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
OneToMany |
- Species where no ortholog for GP6 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for GP6 Gene
Paralogs for GP6 Gene
(33) SIMAP similar genes for GP6 Gene using alignment to 2 proteins:
Variants for GP6 Gene
| SNP ID | Clin | Chr 19 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs199588110 | Bleeding disorder, platelet-type 11 (BDPLT11) [MIM:614201] | ||||
| rs387906919 | Bleeding disorder, platelet-type 11 (BDPLT11) [MIM:614201] | ||||
| rs1613662 | -- | ||||
| rs1654412 | -- | ||||
| rs1654413 | -- |
Residual Variation Intolerance Score:
89.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
8.60;
86.20% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for GP6 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GP6 Gene
Disorders for GP6 Gene
(22) MalaCards diseases for GP6 Gene - From: OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| bleeding disorder, platelet-type, 11 |
|
|
| cervical adenosarcoma |
|
|
| sticky platelet syndrome |
|
|
| anogenital venereal wart |
|
|
| balanoposthitis |
|
|
Search GP6 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
GPVI_HUMAN- Bleeding disorder, platelet-type 11 (BDPLT11) [MIM:614201]: A mild to moderate bleeding disorder caused by defective platelet activation and aggregation in response to collagen. {ECO:0000269 PubMed:19549989, ECO:0000269 PubMed:19552682}. Note=The disease is caused by mutations affecting the gene represented in this entry.
Relevant External Links for GP6
No data available for Genatlas for GP6 Gene
Publications for GP6 Gene
- Molecular cloning, genomic structure, chromosomal localization, and alternative splice forms of the platelet collagen receptor glycoprotein VI. (PMID: 11027634) Ezumi Y. … Takayama H. (Biochem. Biophys. Res. Commun. 2000) 2 3 4 22 64
- Absence of collagen-induced platelet activation caused by compound heterozygous GPVI mutations. (PMID: 19549989) Dumont B. … Jandrot-Perrus M. (Blood 2009) 3 4 22 64
- Gain- and loss-of-function mutants confirm the importance of apical residues to the primary interaction of human glycoprotein VI with collagen. (PMID: 16405521) O'connor M.N. … Ouwehand W.H. (J. Thromb. Haemost. 2006) 3 4 22 64
- Structural basis for platelet collagen responses by the immune-type receptor glycoprotein VI. (PMID: 16861347) Horii K. … Herr A.B. (Blood 2006) 3 4 22 64
- Polymorphisms of COX-1 and GPVI associate with the antiplatelet effect of aspirin in coronary artery disease patients. (PMID: 16493486) LepAontalo A. … Lassila R. (Thromb. Haemost. 2006) 3 22 46 64
Products for GP6 Gene
- R&D Systems Antibodies for GP6 (GPVI)
- R&D Systems Proteins and Enzymes for GP6 (GPVI)
- Browse R&D Systems for biochemical assays
- R&D Systems cDNA Clones for GP6 (GPVI)
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for GP6
- Search Origene for MassSpec and Protein Over-expression Lysates for GP6
- Origene Custom Protein Services for GP6
- Origene shRNA, siRNA, and RNAi products in human, mouse, rat for GP6
- Browse OriGene Inhibitory RNA Products For GP6
- OriGene qPCR primer pairs and template standards for GP6
- OriGene qPCR primer pairs for GP6
- OriGene CRISPR knockouts for GP6
- OriGene ORF clones in human for GP6
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For GP6
- GenScript: Next-day shipping cDNA ORF clone for GP6 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for GP6
- GenScript Custom Assay Services for GP6
- GenScript Custom overexpressing Cell Line Services for GP6
- GenScript: Design CRISPR guide RNA sequences for GP6
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for GP6
- Browse Sino Biological cDNA Clones
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Proteins
- Sino Biological Antibodies
- Sino Biological ELISA Kits and Pair Sets
- Sino Biological Cell Lysates
- Sino Biological qPCR Primers
- Sino Biological CRO Services for Proteins, Antibodies and Genes
- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for GP6
- Novus Biologicals proteins and lysates for GP6
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Cloud-Clone Corp. Antibodies for GP6
- Cloud-Clone Corp. Proteins for GP6
- Cloud-Clone Corp Assay Kits for GP6
- Taconic Biosciences Mouse Models for GP6
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- antibodies-online Antibodies for GP6: See all 66
- antibodies-online Kits for GP6: See all 30
- antibodies-online Proteins for GP6: See all 5
- Search antibodies-online for peptides
- GeneTex GP6 antibody for GP6
- Search GeneTex for Proteins for GP6
- ViGene Biosciences adenoviral particle packaged cDNA for GP6 gene
- ViGene Biosciences lentiviral particle packaged cDNA for GP6 gene
- ViGene Biosciences ready-to-package AAV shRNAs for GP6 gene
- Search ViGene Biosciences for GP6
- Santa Cruz Biotechnology (SCBT) Antibodies for GP6
- Search Santa Cruz Biotechnology (SCBT) for GP6 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for GP6
- Custom Antibody ServicesProSci Antibodies for GP6
- Search for GP6 Proteins at ProSci
- Horizon Cell Lines for GP6
- Cyagen custom Knockout/knockin (KOKI) mouse models for GP6
- VectorBuilder custom plasmid, inducible vectors for GP6
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for GP6
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for GP6 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
- (125) UMLS
- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer