Aliases for GP2 Gene
External Ids for GP2 Gene
Previous GeneCards Identifiers for GP2 Gene
This gene encodes an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. The encoded protein binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
GeneCards Summary for GP2 Gene
GP2 (Glycoprotein 2) is a Protein Coding gene. Diseases associated with GP2 include Swine Influenza and Familial Juvenile Hyperuricaemic Nephropathy. Among its related pathways are Metabolism of proteins and Post-translational modification- synthesis of GPI-anchored proteins. GO annotations related to this gene include antigen binding. An important paralog of this gene is UMOD.