Free for academic non-profit institutions. Other users need a Commercial license

Aliases for GOLT1B Gene

Aliases for GOLT1B Gene

  • Golgi Transport 1B 2 3 5
  • Putative NF-Kappa-B-Activating Protein 470 3 4
  • Germ Cell Tumor 2 3 4
  • HGOT1a 3 4
  • GCT2 3 4
  • Golgi Transport 1 Homolog B (S. Cerevisiae) 2
  • Golgi Transport 1 Homolog B 4
  • CGI-141 3
  • YMR292W 3
  • GOT1B 3
  • GOT1A 4
  • GOT1 3

External Ids for GOLT1B Gene

Previous GeneCards Identifiers for GOLT1B Gene

  • GC12P021547
  • GC12P021654
  • GC12P021428

Summaries for GOLT1B Gene

GeneCards Summary for GOLT1B Gene

GOLT1B (Golgi Transport 1B) is a Protein Coding gene. GO annotations related to this gene include signal transducer activity and lipase activity. An important paralog of this gene is GOLT1A.

UniProtKB/Swiss-Prot for GOLT1B Gene

  • May be involved in fusion of ER-derived transport vesicles with the Golgi complex.

Gene Wiki entry for GOLT1B Gene

No data available for Entrez Gene Summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GOLT1B Gene

Genomics for GOLT1B Gene

Regulatory Elements for GOLT1B Gene

Enhancers for GOLT1B Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around GOLT1B on UCSC Golden Path with GeneCards custom track

Promoters for GOLT1B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around GOLT1B on UCSC Golden Path with GeneCards custom track

Genomic Location for GOLT1B Gene

21,501,765 bp from pter
21,518,408 bp from pter
16,644 bases
Plus strand

Genomic View for GOLT1B Gene

Genes around GOLT1B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GOLT1B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GOLT1B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GOLT1B Gene

Proteins for GOLT1B Gene

  • Protein details for GOLT1B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Vesicle transport protein GOT1B
    Protein Accession:
    Secondary Accessions:
    • B2R4R4
    • Q54A40
    • Q6I9W6
    • Q9P1R9

    Protein attributes for GOLT1B Gene

    138 amino acids
    Molecular mass:
    15426 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAF65181.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

neXtProt entry for GOLT1B Gene

Proteomics data for GOLT1B Gene at MOPED

Post-translational modifications for GOLT1B Gene

  • Ubiquitination at Lys 62
  • Modification sites at PhosphoSitePlus

Other Protein References for GOLT1B Gene

No data available for DME Specific Peptides for GOLT1B Gene

Domains & Families for GOLT1B Gene

Protein Domains for GOLT1B Gene


Suggested Antigen Peptide Sequences for GOLT1B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the GOT1 family.
  • Belongs to the GOT1 family.
genes like me logo Genes that share domains with GOLT1B: view

No data available for Gene Families for GOLT1B Gene

Function for GOLT1B Gene

Molecular function for GOLT1B Gene

UniProtKB/Swiss-Prot Function:
May be involved in fusion of ER-derived transport vesicles with the Golgi complex.
genes like me logo Genes that share phenotypes with GOLT1B: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GOLT1B Gene

Localization for GOLT1B Gene

Subcellular locations from UniProtKB/Swiss-Prot for GOLT1B Gene

Golgi apparatus membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for GOLT1B Gene COMPARTMENTS Subcellular localization image for GOLT1B gene
Compartment Confidence
endoplasmic reticulum 5
golgi apparatus 3
plasma membrane 2
lysosome 1
peroxisome 1
vacuole 1

Gene Ontology (GO) - Cellular Components for GOLT1B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005783 endoplasmic reticulum IDA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with GOLT1B: view

Pathways & Interactions for GOLT1B Gene

SuperPathways for GOLT1B Gene

No Data Available

Gene Ontology (GO) - Biological Process for GOLT1B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0015031 protein transport IEA --
genes like me logo Genes that share ontologies with GOLT1B: view

No data available for Pathways by source and SIGNOR curated interactions for GOLT1B Gene

Drugs & Compounds for GOLT1B Gene

No Compound Related Data Available

Transcripts for GOLT1B Gene

Unigene Clusters for GOLT1B Gene

Golgi transport 1B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for GOLT1B Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d
SP1: - -
SP2: - - -
SP3: - - -
SP4: - -
SP5: - - - - -
SP6: - - - - - -

Relevant External Links for GOLT1B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for GOLT1B Gene

mRNA expression in normal human tissues for GOLT1B Gene

Protein differential expression in normal tissues from HIPED for GOLT1B Gene

This gene is overexpressed in Nasal epithelium (49.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for GOLT1B Gene

SOURCE GeneReport for Unigene cluster for GOLT1B Gene Hs.62275

mRNA Expression by UniProt/SwissProt for GOLT1B Gene

Tissue specificity: Widely expressed. Tends to be up-regulated in seminomas compared to normal testis.
genes like me logo Genes that share expression patterns with GOLT1B: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and Protein tissue co-expression partners for GOLT1B Gene

Orthologs for GOLT1B Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for GOLT1B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia GOLT1B 35
  • 94.44 (n)
  • 100 (a)
  • 100 (a)
(Canis familiaris)
Mammalia GOLT1B 35
  • 96.14 (n)
  • 99.28 (a)
  • 84 (a)
(Mus musculus)
Mammalia Golt1b 35
  • 89.37 (n)
  • 98.55 (a)
Golt1b 16
Golt1b 36
  • 99 (a)
(Pan troglodytes)
Mammalia GOLT1B 35
  • 100 (n)
  • 100 (a)
  • 100 (a)
(Rattus norvegicus)
Mammalia Golt1b 35
  • 89.86 (n)
  • 99.28 (a)
(Monodelphis domestica)
Mammalia GOLT1B 36
  • 93 (a)
(Ornithorhynchus anatinus)
Mammalia GOLT1B 36
  • 88 (a)
(Gallus gallus)
Aves GOLT1B 35
  • 86.96 (n)
  • 94.93 (a)
(Anolis carolinensis)
Reptilia GOLT1B 36
  • 90 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia golt1b 35
  • 75.33 (n)
  • 91.34 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.33070 35
(Danio rerio)
Actinopterygii golt1bb 35
  • 73.43 (n)
  • 87.68 (a)
golt1ba 36
  • 86 (a)
golt1bb 36
  • 86 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP002357 35
  • 60.54 (n)
  • 68.38 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG32576 35
  • 61.76 (n)
  • 64.71 (a)
CG32576 36
  • 62 (a)
(Caenorhabditis elegans)
Secernentea F41C3.4 35
  • 57.21 (n)
  • 47.01 (a)
F41C3.4 36
  • 47 (a)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AGR337W 35
  • 46.25 (n)
  • 38.76 (a)
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0A09801g 35
  • 50.65 (n)
  • 37.21 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes GOT1 35
  • 55.3 (n)
  • 42.64 (a)
GOT1 36
  • 41 (a)
GOT1 38
thale cress
(Arabidopsis thaliana)
eudicotyledons AT3G49420 35
  • 57.55 (n)
  • 50.78 (a)
(Oryza sativa)
Liliopsida Os03g0209400 35
  • 58.07 (n)
  • 50.78 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU06396 35
  • 54.79 (n)
  • 47.52 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.5537 36
  • 62 (a)
Species with no ortholog for GOLT1B:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for GOLT1B Gene

Gene Tree for GOLT1B (if available)
Gene Tree for GOLT1B (if available)

Paralogs for GOLT1B Gene

Paralogs for GOLT1B Gene

(1) SIMAP similar genes for GOLT1B Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with GOLT1B: view

Variants for GOLT1B Gene

Sequence variations from dbSNP and Humsavar for GOLT1B Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs2080102 -- 21,511,266(+) TAAAG(C/G)ATATT intron-variant
rs2080103 -- 21,511,272(+) ATATT(A/G)CAAAG intron-variant
rs2080104 -- 21,511,446(+) CATGA(C/T)TGATT intron-variant
rs1366 -- 21,516,093(-) GGACA(C/T)TTCTA utr-variant-3-prime
rs7135694 -- 21,512,943(+) TGCCT(A/G)TAGTC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for GOLT1B Gene

Variant ID Type Subtype PubMed ID
nsv898896 CNV Gain 21882294
nsv528556 CNV Gain 19592680

Variation tolerance for GOLT1B Gene

Residual Variation Intolerance Score: 59.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.34; 26.58% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for GOLT1B Gene

Disorders for GOLT1B Gene

Relevant External Links for GOLT1B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for GOLT1B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GOLT1B Gene

Publications for GOLT1B Gene

  1. Genomic and expression analysis of the 12p11-p12 amplicon using EST arrays identifies two novel amplified and overexpressed genes. (PMID: 12414650) Bourdon V. … Chaganti R.S. (Cancer Res. 2002) 2 3 4 67
  2. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PMID: 10810093) Lai C.-H. … Lin W.-C. (Genome Res. 2000) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  5. A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface. (PMID: 26638075) Gupta G.D. … Pelletier L. (Cell 2015) 3

Products for GOLT1B Gene

Sources for GOLT1B Gene