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GOLPH3L Gene

protein-coding   GIFtS: 52
GCID: GC01M150618

Golgi Phosphoprotein 3-Like

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Golgi Phosphoprotein 3-Like1 2
GPP34R2 3 5
GPP34-Related Protein2 3

External Ids:    HGNC: 248821   Entrez Gene: 552042   Ensembl: ENSG000001434577   OMIM: 6122085   UniProtKB: Q9H4A53   

Export aliases for GOLPH3L gene to outside databases

Previous GC identifers: GC01M147432 GC01M148885 GC01M121996


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for GOLPH3L Gene:
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic
reticulum. The protein encoded by this gene is localized at the Golgi stack and may have a regulatory role in
Golgi trafficking. (provided by RefSeq, Jul 2008)

GeneCards Summary for GOLPH3L Gene:
GOLPH3L (golgi phosphoprotein 3-like) is a protein-coding gene. Diseases associated with GOLPH3L include retinal detachment, and retinitis. GO annotations related to this gene include phosphatidylinositol-4-phosphate binding. An important paralog of this gene is GOLPH3.

UniProtKB/Swiss-Prot: GLP3L_HUMAN, Q9H4A5
Function: Phosphatidylinositol-4-phosphate-binding protein that may antagonize the action of GOLPH3 which is
required for the process of vesicle budding at the Golgi and anterograde transport to the plasma membrane




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NT_004487.20  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the GOLPH3L gene promoter:
         SRF   HFH-3   RP58   SRF (504 AA)   GATA-1   FOXI1   POU2F1   POU2F1a   FOXJ2 (long isoform)   FOXJ2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGOLPH3L promoter sequence
   Search Chromatin IP Primers for GOLPH3L

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat GOLPH3L


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21.3   Ensembl cytogenetic band:  1q21.3   HGNC cytogenetic band: 1q21

GOLPH3L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GOLPH3L gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M150618:  view genomic region     (about GC identifiers)

Start:
150,618,701 bp from pter      End:
150,669,672 bp from pter
Size:
50,972 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: GLP3L_HUMAN, Q9H4A5 (See protein sequence)
Recommended Name: Golgi phosphoprotein 3-like  
Size: 285 amino acids; 32767 Da
Subunit: Homooligomer (By similarity). Does not interact MYO18; differs from GOLPH3 by its inability to interact
with MYO18. May interact with ARF1
Sequence caution: Sequence=BAA91750.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: B1AN09 Q9NVK0

Explore the universe of human proteins at neXtProt for GOLPH3L: NX_Q9H4A5

Explore proteomics data for GOLPH3L at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See GOLPH3L Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060648.2  
    ENSEMBL proteins: 
     ENSP00000271732   ENSP00000410476   ENSP00000446070  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR008628 GPP34

    Graphical View of Domain Structure for InterPro Entry Q9H4A5

    ProtoNet protein and cluster: Q9H4A5

    1 Blocks protein domain: IPB008628 Golgi phosphoprotein 3

    UniProtKB/Swiss-Prot: GLP3L_HUMAN, Q9H4A5
    Similarity: Belongs to the GOLPH3/VPS74 family


    GOLPH3L for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GLP3L_HUMAN, Q9H4A5
    Function: Phosphatidylinositol-4-phosphate-binding protein that may antagonize the action of GOLPH3 which is
    required for the process of vesicle budding at the Golgi and anterograde transport to the plasma membrane

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0070273phosphatidylinositol-4-phosphate binding IDA--
         
    GOLPH3L for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for GOLPH3L:
     Large cells 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for GOLPH3L
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    miRNA
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    miRTarBase miRNAs that target GOLPH3L:
    hsa-mir-15a-5p (MIRT000849), hsa-mir-16-5p (MIRT000848), hsa-mir-128-3p (MIRT022020)

    Block miRNA regulation of human, mouse, rat GOLPH3L using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate GOLPH3L (see all 32):
    hsa-miR-3074-3p hsa-miR-449a hsa-miR-3921 hsa-miR-29b-1* hsa-miR-570 hsa-miR-29a* hsa-miR-23a hsa-miR-761
    SwitchGear 3'UTR luciferase reporter plasmidGOLPH3L 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat GOLPH3L

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: GOLPH3L (NM_018178)
    Sino Biological Human cDNA Clone for GOLPH3L
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for GOLPH3L
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GOLPH3L

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GOLPH3L


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    GLP3L_HUMAN, Q9H4A5: Golgi apparatus, Golgi stack membrane; Peripheral membrane protein; Cytoplasmic side. Golgi
    apparatus, trans-Golgi network membrane; Peripheral membrane protein; Cytoplasmic side. Note=Phosphatidylinositol
    4-phosphate (PtdIns4P)-binding mediates recruitment to Golgi membranes
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    golgi apparatus5
    nucleus3

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IC--
    GO:0032580Golgi cisterna membrane IEA--
    GO:0032588trans-Golgi network membrane IC--

    GOLPH3L for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for GOLPH3L About    
    See pathways by source

    SuperPathContained pathways About
    1Transcriptional misregulation in cancer
    Transcriptional misregulation in cancer

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways




    1 Kegg Pathway  (Kegg details for GOLPH3L):
        Transcriptional misregulation in cancer


    GOLPH3L for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for GOLPH3L
    Interactions:

        Search GeneGlobe Interaction Network for GOLPH3L

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    Selected Interacting proteins for GOLPH3L (Q9H4A51, 3 ENSP000002717324) via UniProtKB, MINT, STRING, and/or I2D (see all 55)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARCN1P484443, ENSP000002640284I2D: score=1 STRING: ENSP00000264028
    COPG2Q9UBF23, ENSP000003939124I2D: score=1 STRING: ENSP00000393912
    KIAA0368Q5VYK33, ENSP000002593354I2D: score=1 STRING: ENSP00000259335
    COPAP536213, ENSP000003570484I2D: score=1 STRING: ENSP00000357048
    COPB1P536183, ENSP000002499234I2D: score=1 STRING: ENSP00000249923
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    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007030Golgi organization IMP--
    GO:0050714positive regulation of protein secretion IMP--

    GOLPH3L for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for GOLPH3L (GLP3L)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for GOLPH3L gene: 
    NM_018178.5  

    Unigene Cluster for GOLPH3L:

    Golgi phosphoprotein 3-like
    Hs.203699  [show with all ESTs]
    Unigene Representative Sequence: NM_018178
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000271732(uc001evj.2 uc010pci.1) ENST00000427665 ENST00000479757
    ENST00000540514
    miRNA
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    Block miRNA regulation of human, mouse, rat GOLPH3L using miScript Target Protectors
    32 qRT-PCR Assays for microRNAs that regulate GOLPH3L (see first 8):
    hsa-miR-3074-3p hsa-miR-449a hsa-miR-3921 hsa-miR-29b-1* hsa-miR-570 hsa-miR-29a* hsa-miR-23a hsa-miR-761
    hsa-miR-490-3p hsa-miR-3163 hsa-miR-34c-5p hsa-miR-449b hsa-miR-130a* hsa-miR-23c hsa-miR-593 hsa-miR-23b
    hsa-miR-3675-3p hsa-miR-3920 hsa-miR-1226 hsa-miR-3660 hsa-miR-3133 hsa-miR-3692 hsa-miR-3119 hsa-miR-548c-3p
    hsa-miR-3650 hsa-miR-3611 hsa-miR-146a* hsa-miR-214 hsa-miR-34a hsa-miR-377 hsa-miR-4276 hsa-let-7f-2*
    SwitchGear 3'UTR luciferase reporter plasmidGOLPH3L 3' UTR sequence
    Inhib. RNA
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    OriGene qPCR primer pairs and template standards for GOLPH3L
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat GOLPH3L
      QuantiTect SYBR Green Assays in human, mouse, rat GOLPH3L
      QuantiFast Probe-based Assays in human, mouse, rat GOLPH3L

    Additional mRNA sequence: 

    AJ296153.1 AK001549.1 AK300635.1 AK315594.1 BC013870.2 

    9 DOTS entries:

    DT.91785466  DT.100760947  DT.100685558  DT.100694501  DT.121367804  DT.121367815  DT.121368030  DT.121368034 
    DT.95359583 

    Selected AceView cDNA sequences (see all 156):

    BF001715 BQ267824 BQ184958 AW445094 BM928226 AI623448 BM674827 CB243830 
    AL703369 BF591231 BG742527 BM273025 BM451954 BM969175 NM_018178 BM717550 
    AU130135 BM750834 CR622887 AA232616 AI017699 AA147436 AI762255 BP341735 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for GOLPH3L (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c · 7d
    SP1:                                -           -     -                                             
    SP2:                                -           -     -                                             
    SP3:                                -           -                                                   
    SP4:                                            -     -                                             
    SP5:                                -           -     -                 -                           


    ECgene alternative splicing isoforms for GOLPH3L

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    GOLPH3L expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATTGAAACC
    GOLPH3L Expression
    About this image


    GOLPH3L expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Eye (Sensory Organs)
             Retina
    GOLPH3L Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    GOLPH3L Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.203699
        Custom PCR Arrays for GOLPH3L
    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat GOLPH3L
    QuantiTect SYBR Green Assays in human, mouse, rat GOLPH3L
    QuantiFast Probe-based Assays in human, mouse, rat GOLPH3L
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GOLPH3L

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for GOLPH3L gene from Selected species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Golph3l1 , 5 golgi phosphoprotein 3-like1, 5 89.59(n)1
    95.09(a)1
      3 (40.74 cM)5
    2295931  NM_146133.31  NP_666245.21 
     955889345 
    chicken
    (Gallus gallus)
    Aves GOLPH3L1 golgi phosphoprotein 3-like 68.22(n)
    72.4(a)
      425072  XM_004948290.1  XP_004948347.1 
    lizard
    (Anolis carolinensis)
    Reptilia GOLPH3L6
    golgi phosphoprotein 3-like
    84(a)
    1 ↔ 1
    GL343862.1(74320-91999)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia CF220195.12   -- 76.53(n)    CF220195.1 
    zebrafish
    (Danio rerio)
    Actinopterygii golph3l1 golgi phosphoprotein 3-like 63.5(n)
    63.73(a)
      569617  NM_001037699.1  NP_001032788.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta l(2)s53796
    lethal (2) s5379
    59(a)
    1 → many
    2L(2226523-2231099)
    worm
    (Caenorhabditis elegans)
    Secernentea Y47G6A.186
    Protein Y47G6A.18 (Y47G6A.18) mRNA, complete cds
    54(a)
    1 → many
    I(3508635-3512733) WBGene00021644
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes VPS741 VPS74 53.62(n)
    50.47(a)
      851978   NP_010660.1 


    ENSEMBL Gene Tree for GOLPH3L (if available)
    TreeFam Gene Tree for GOLPH3L (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for GOLPH3L gene
    GOLPH32  
    1 SIMAP similar gene for GOLPH3L using alignment to 3 protein entries:     GLP3L_HUMAN (see all proteins):
    GOLPH3

    GOLPH3L for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for GOLPH3L (see all 872)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs710865891,2
    C--150625932(+) TTTTT-/TGGAGA 1 -- int11Minor allele frequency- T:0.00NA 2
    rs120585481,2
    A--150666273(+) TATGTA/GTGTGT 1 -- int10--------
    rs112047031,2
    C,A--150666297(+) TGTGTG/ATATAT 1 -- int13Minor allele frequency- A:0.00NA 6
    rs1906257571,2
    --150666299(+) TGTATA/GTATAT 1 -- int10--------
    rs117997141,2
    H--150666311(+) tatatA/Gtatat 1 -- int10--------
    rs127317121,2
    --150666316(+) atataC/Tatata 1 -- int10--------
    rs666273721,2
    C--150666324(+) TATAT-/TT/TT 
     T
    /TTTTT
    TTTTT
    2 -- int1 cds12NA 4
    rs75564891,2
    C--150666325(+) tatatA/Tttttt 1 -- int1 trp31Minor allele frequency- T:0.00NA 2
    rs117997271,2
    C,F,H--150666379(+) catccG/Aggctg 1 -- int11Minor allele frequency- A:0.00NA 2
    rs1409840021,2
    --157119935(+) AATTGA/GCTAAT 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for GOLPH3L (150618701 - 150669672 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for GOLPH3L:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2427260CNV Deletion19546169
    nsv437158CNV Loss16327808
    nsv872417CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612208    OMIM disorders: --

    2 diseases for GOLPH3L:    
    About MalaCards
    retinal detachment    retinitis


    GOLPH3L for disorders           About GeneDecksing

    Genetic Association Database (GAD): GOLPH3L
    Human Genome Epidemiology (HuGE) Navigator: GOLPH3L (1 document)

    Export disorders for GOLPH3L gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for GOLPH3L gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with GOLPH3L)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. GOLPH3L antagonizes GOLPH3 to determine Golgi morphology. (PubMed id 23345592)1, 2 Ng M.M....Field S.J. (Mol. Biol. Cell 2013)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Proteomics characterization of abundant Golgi membrane proteins. (PubMed id 11042173)1, 2 Bell A.W....Bergeron J.J.M. (J. Biol. Chem. 2001)
    5. VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (PLoS ONE 2013)
    6. Development and application of a DNA microarray-based yeast two-hybrid system. (PubMed id 23275563)1 Suter B....Wanker E.E. (Nucleic Acids Res. 2013)
    7. Genome-wide association study identifies genetic risk underlying primary rhegmatogenous retinal detachment. (PubMed id 23585552)1 Kirin M....Mitry D. (Hum. Mol. Genet. 2013)
    8. A conserved N-terminal arginine-motif in GOLPH3-family proteins mediates binding to coatomer. (PubMed id 22889169)2 Tu L.... Banfield D.K. (Traffic 2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    10. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55204 HGNC: 24882 AceView: GPP34R Ensembl:ENSG00000143457 euGenes: HUgn55204
    ECgene: GOLPH3L Kegg: 55204 H-InvDB: GOLPH3L

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for GOLPH3L Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for GOLPH3L gene:
    Search GeneIP for patents involving GOLPH3L

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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