Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GOLPH3L Gene

protein-coding   GIFtS: 51
GCID: GC01M150618

Golgi Phosphoprotein 3-Like

  Search for GOLPH3L
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Golgi Phosphoprotein 3-Like1 2
GPP34R2 3 5
GPP34-Related Protein2 3

External Ids:    HGNC: 248821   Entrez Gene: 552042   Ensembl: ENSG000001434577   OMIM: 6122085   UniProtKB: Q9H4A53   

Export aliases for GOLPH3L gene to outside databases

Previous GC identifers: GC01M147432 GC01M148885 GC01M121996


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GOLPH3L Gene:
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic
reticulum. The protein encoded by this gene is localized at the Golgi stack and may have a regulatory role in
Golgi trafficking. (provided by RefSeq, Jul 2008)

GeneCards Summary for GOLPH3L Gene: 
GOLPH3L (golgi phosphoprotein 3-like) is a protein-coding gene. GO annotations related to this gene include lipid binding. An important paralog of this gene is GOLPH3.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_004487.19  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GOLPH3L gene promoter:
         SRF   HFH-3   RP58   SRF (504 AA)   GATA-1   FOXI1   POU2F1   POU2F1a   FOXJ2 (long isoform)   FOXJ2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGOLPH3L promoter sequence
   Search SABiosciences Chromatin IP Primers for GOLPH3L

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GOLPH3L


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21.3   Ensembl cytogenetic band:  1q21.3   HGNC cytogenetic band: 1q21

GOLPH3L Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GOLPH3L gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M150618:  view genomic region     (about GC identifiers)

Start:
150,618,701 bp from pter      End:
150,669,672 bp from pter
Size:
50,972 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: GLP3L_HUMAN, Q9H4A5 (See protein sequence)
Recommended Name: Golgi phosphoprotein 3-like  
Size: 285 amino acids; 32767 Da
Subunit: Homotetramer (By similarity)
Subcellular location: Cytoplasm (By similarity). Golgi apparatus, Golgi stack membrane; Peripheral membrane
protein; Cytoplasmic side (By similarity). Note=Phosphatidylinositol 4-phosphate (PtdIns4P) binding is essential
for Golgi localization (By similarity)
Sequence caution: Sequence=BAA91750.1; Type=Erroneous initiation;
Secondary accessions: B1AN09 Q9NVK0

Explore the universe of human proteins at neXtProt for GOLPH3L: NX_Q9H4A5

Explore proteomics data for GOLPH3L at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H4A5

  • GOLPH3L Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    GOLPH3L Protein Expression
    REFSEQ proteins: NP_060648.2  
    ENSEMBL proteins: 
     ENSP00000271732   ENSP00000410476   ENSP00000446070  

    Human Recombinant Protein Products for GOLPH3L: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for GOLPH3L
    OriGene Protein Over-expression Lysate for GOLPH3L
    OriGene MassSpec for GOLPH3L 
    OriGene Custom Protein Services for GOLPH3L
    GenScript Custom Purified and Recombinant Proteins Services for GOLPH3L
    Novus Biologicals GOLPH3L Protein
    Novus Biologicals GOLPH3L Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for GOLPH3L 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IC--
    GO:0032580Golgi cisterna membrane IEA--
    GO:0032588trans-Golgi network membrane IC--

    GOLPH3L for ontologies           About GeneDecksing



    GOLPH3L Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for GOLPH3L
    GenScript Custom Superior Antibodies Services for GOLPH3L
    Novus Biologicals GOLPH3L Antibody
    Abcam antibodies for GOLPH3L
    Cloud-Clone Corp. Antibodies for GOLPH3L 
    Search ThermoFisher Antibodies for GOLPH3L
    LSBio Antibodies in human, mouse, rat for GOLPH3L 

    Assay Products for GOLPH3L: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for GOLPH3L
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for GOLPH3L
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for GOLPH3L 
    Cloud-Clone Corp. CLIAs for GOLPH3L


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR008628 GPP34

    Graphical View of Domain Structure for InterPro Entry Q9H4A5

    ProtoNet protein and cluster: Q9H4A5

    1 Blocks protein domain: IPB008628 Golgi phosphoprotein 3

    UniProtKB/Swiss-Prot: GLP3L_HUMAN, Q9H4A5
    Similarity: Belongs to the GOLPH3/VPS74 family


    GOLPH3L for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0008289lipid binding ----
    GO:0070273phosphatidylinositol-4-phosphate binding IDA--
         
    GOLPH3L for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for GOLPH3L:
     Large cells 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for GOLPH3L 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for GOLPH3L

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for GOLPH3L 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for GOLPH3L 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GOLPH3L
    8/32 QIAGEN miScript miRNA Assays for microRNAs that regulate GOLPH3L (see all 32):
    hsa-miR-3074-3p hsa-miR-449a hsa-miR-3921 hsa-miR-29b-1* hsa-miR-570 hsa-miR-29a* hsa-miR-23a hsa-miR-761
    SwitchGear 3'UTR luciferase reporter plasmidGOLPH3L 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for GOLPH3L
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GOLPH3L

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for GOLPH3L
    Sirion Biotech Customized adenovirus for overexpression of GOLPH3L

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for GOLPH3L (see all 7)
    OriGene ORF clones in mouse, rat for GOLPH3L
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: GOLPH3L (NM_018178)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for GOLPH3L
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GOLPH3L
    Sirion Biotech Customized lentivirus for stable overexpression of GOLPH3L 
                         Customized lentivirus expression plasmids for stable overexpression of GOLPH3L 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for GOLPH3L
    Search LifeMap BioReagents cell lines for GOLPH3L
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GOLPH3L


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for GOLPH3L About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Transcriptional misregulation in cancer
    Transcriptional misregulation in cancer

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    1         Kegg Pathway  (Kegg details for GOLPH3L):
        Transcriptional misregulation in cancer


    GOLPH3L for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GOLPH3L

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    5/50 Interacting proteins for GOLPH3L (Q9H4A51, 3 ENSP000002717324) via UniProtKB, MINT, STRING, and/or I2D (see all 50)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARCN1P484443, ENSP000002640284I2D: score=1 STRING: ENSP00000264028
    COPAP536213, ENSP000003570484I2D: score=1 STRING: ENSP00000357048
    COPB1P536183, ENSP000002499234I2D: score=1 STRING: ENSP00000249923
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    VPS26BQ4G0F53I2D: score=5 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007030Golgi organization IMP--
    GO:0050714positive regulation of protein secretion IMP--

    GOLPH3L for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GOLPH3L (GLP3L)

    Search CenterWatch for drugs/clinical trials and news about GOLPH3L / GLP3L

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GOLPH3L gene: 
    NM_018178.5  

    Unigene Cluster for GOLPH3L:

    Golgi phosphoprotein 3-like
    Hs.203699  [show with all ESTs]
    Unigene Representative Sequence: NM_018178
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000271732(uc001evj.2 uc010pci.1) ENST00000427665 ENST00000479757
    ENST00000540514
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GOLPH3L
    8/32 QIAGEN miScript miRNA Assays for microRNAs that regulate GOLPH3L (see all 32):
    hsa-miR-3074-3p hsa-miR-449a hsa-miR-3921 hsa-miR-29b-1* hsa-miR-570 hsa-miR-29a* hsa-miR-23a hsa-miR-761
    SwitchGear 3'UTR luciferase reporter plasmidGOLPH3L 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for GOLPH3L
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GOLPH3L
    Clone
    Products:
         
    OriGene clones in human, mouse for GOLPH3L (see all 7)
    OriGene ORF clones in mouse, rat for GOLPH3L
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: GOLPH3L (NM_018178)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for GOLPH3L
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GOLPH3L
    Sirion Biotech Customized lentivirus for stable overexpression of GOLPH3L 
                         Customized lentivirus expression plasmids for stable overexpression of GOLPH3L 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for GOLPH3L
    OriGene qSTAR qPCR primer pairs in human, mouse for GOLPH3L
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat GOLPH3L
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GOLPH3L
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GOLPH3L

    Additional mRNA sequence: 

    AJ296153.1 AK001549.1 AK300635.1 AK315594.1 BC013870.2 

    9 DOTS entries:

    DT.91785466  DT.100760947  DT.100685558  DT.100694501  DT.121367804  DT.121367815  DT.121368030  DT.121368034 
    DT.95359583 

    24/156 AceView cDNA sequences (see all 156):

    BF591231 BM928226 BM451954 BM750834 AA232616 AL703369 BG742527 NM_018178 
    BM717550 BQ018943 CR622887 BF001715 AI623448 CB243830 CB149454 BM674827 
    BM273025 BQ184958 BM969175 BQ267824 AW445094 AU130135 AA147436 BP341735 

    GeneLoc Exon Structure

    5/7 Alternative Splicing Database (ASD) splice patterns (SP) for GOLPH3L (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b · 7c · 7d
    SP1:                                -           -     -                                             
    SP2:                                -           -     -                                             
    SP3:                                -           -                                                   
    SP4:                                            -     -                                             
    SP5:                                -           -     -                 -                           


    ECgene alternative splicing isoforms for GOLPH3L

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GOLPH3L expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATTGAAACC
    GOLPH3L Expression
    About this image


    See GOLPH3L Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GOLPH3L

    SOURCE GeneReport for Unigene cluster: Hs.203699
        SABiosciences Custom PCR Arrays for GOLPH3L
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for GOLPH3L
    OriGene qSTAR qPCR primer pairs in human, mouse for GOLPH3L
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat GOLPH3L
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GOLPH3L
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GOLPH3L
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GOLPH3L

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for GOLPH3L gene from 6/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Golph3l1 , 5 golgi phosphoprotein 3-like1, 5 89.59(n)1
    95.09(a)1
      3 (40.74 cM)5
    2295931  NM_146133.31  NP_666245.21 
     955889345 
    chicken
    (Gallus gallus)
    Aves GOLPH3L1 golgi phosphoprotein 3-like 68.22(n)
    72.4(a)
      425072  XM_422865.3  XP_422865.3 
    lizard
    (Anolis carolinensis)
    Reptilia GOLPH3L6
    Uncharacterized protein
    84(a)
    1 ↔ 1
    GL343862.1(74320-91999)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia CF220195.12   -- 76.53(n)    CF220195.1 
    zebrafish
    (Danio rerio)
    Actinopterygii golph3l1 golgi phosphoprotein 3-like 63.5(n)
    63.73(a)
      569617  NM_001037699.1  NP_001032788.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes VPS746
    Protein required for Golgi localization of glycosy...
    33(a)
    1 → many
    IV(1221112-1222149)


    ENSEMBL Gene Tree for GOLPH3L (if available)
    TreeFam Gene Tree for GOLPH3L (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GOLPH3L gene
    GOLPH32  
    1 SIMAP similar gene for GOLPH3L using alignment to 3 protein entries:     GLP3L_HUMAN (see all proteins):
    GOLPH3

    GOLPH3L for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/872 SNPs in GOLPH3L are shown (see all 872)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs710865891,2
    C--150625932(+) TTTTT-/TGGAGA 1 -- int11Minor allele frequency- T:0.00NA 2
    rs120585481,2
    A--150666273(+) TATGTA/GTGTGT 1 -- int10--------
    rs112047031,2
    C,A--150666297(+) TGTGTG/ATATAT 1 -- int13Minor allele frequency- A:0.00NA 6
    rs1906257571,2
    --150666299(+) TGTATA/GTATAT 1 -- int10--------
    rs117997141,2
    H--150666311(+) tatatA/Gtatat 1 -- int10--------
    rs127317121,2
    --150666316(+) atataC/Tatata 1 -- int10--------
    rs666273721,2
    C--150666324(+) TATAT-/TT/TT 
     T
    /TTTTT
    TTTTT
    2 -- int1 cds12NA 4
    rs75564891,2
    C--150666325(+) tatatA/Tttttt 1 -- int1 trp31Minor allele frequency- T:0.00NA 2
    rs117997271,2
    C,F,H--150666379(+) catccG/Aggctg 1 -- int11Minor allele frequency- A:0.00NA 2
    rs1409840021,2
    --157119935(+) AATTGA/GCTAAT 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for GOLPH3L (150618701 - 150669672 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for GOLPH3L:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2427260CNV Deletion19546169
    nsv437158CNV Loss16327808
    nsv872417CNV Loss21882294

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing GOLPH3L
    DNA2.0 Custom Variant and Variant Library Synthesis for GOLPH3L

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    GOLPH3L for disorders           About MalaCards
    OMIM gene information: 612208    OMIM disorders: --


    GOLPH3L for disorders           About GeneDecksing

    Genetic Association Database (GAD): GOLPH3L
    Human Genome Epidemiology (HuGE) Navigator: GOLPH3L (1 document)

    Export disorders for GOLPH3L gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GOLPH3L gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with GOLPH3L)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Proteomics characterization of abundant Golgi membrane proteins. (PubMed id 11042173)1, 2 Bell A.W....Bergeron J.J.M. (2001)
    4. VCP phosphorylation-dependent interaction partners pre vent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (2013)
    5. Development and application of a DNA microarray-based yeast two-hybrid system. (PubMed id 23275563)1 Suter B....Wanker E.E. (2013)
    6. Genome-wide association study identifies genetic risk underlying primary rhegmatogenous retinal detachment. (PubMed id 23585552)1 Kirin M....Mitry D. (2013)
    7. GOLPH3L antagonizes GOLPH3 to determine Golgi morpholo gy. (PubMed id 23345592)1 Ng M.M....Field S.J. (2013)
    8. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55204 HGNC: 24882 AceView: GPP34R Ensembl:ENSG00000143457 euGenes: HUgn55204
    ECgene: GOLPH3L Kegg: 55204 H-InvDB: GOLPH3L

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GOLPH3L Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for GOLPH3L gene:
    Search GeneIP for patents involving GOLPH3L

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for GOLPH3L  
     OriGene qPCR primer pairs and template standards for GOLPH3L   OriGene Protein Over-expression Lysate for GOLPH3L  
     OriGene MassSpec something-or-other for GOLPH3L   OriGene clones in human, mouse for GOLPH3L  
     OriGene qSTAR qPCR primer pairs in human, mouse for GOLPH3L   OriGene Purified Protein for GOLPH3L  
     OriGene ORF clones in mouse, rat for GOLPH3L   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for GOLPH3L   OriGene Custom Protein Services for GOLPH3L  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat GOLPH3L
     QIAGEN SeqTarget long-range PCR primers for resequencing GOLPH3L
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GOLPH3L
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GOLPH3L
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GOLPH3L
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GOLPH3L
     GenScript Custom Purified and Recombinant Proteins Services for GOLPH3L GenScript cDNA clones with any tag delivered in your preferred vector for GOLPH3L
     GenScript Custom Assay Services for GOLPH3L GenScript Custom Superior Antibodies Services for GOLPH3L
     GenScript Custom overexpressing Cell Line Services for GOLPH3L CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in GOLPH3L promoter
     Search Chromatin IP Primers for GOLPH3L
     RT2 qPCR Primer Assay in human, mouse, rat GOLPH3L
     Search GNC Networks for GOLPH3L
     SABiosciences Custom PCR Arrays for GOLPH3L
     Search Tocris compounds for GOLPH3L (GLP3L)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     GOLPH3L antibodies
     GOLPH3L proteins
     GOLPH3L lysates
     Antibodies for GOLPH3L
     See all of Abcam's Antibodies, Kits and Proteins for GOLPH3L
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for GOLPH3L
     Antibodies for GOLPH3L
     ELISAs for GOLPH3L
     CLIAs for GOLPH3L
     Search LifeMap BioReagents cell lines for GOLPH3L
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GOLPH3L
     SwitchGear 3'UTR luciferase reporter plasmids for GOLPH3L
     SwitchGear Promoter luciferase reporter plasmids for GOLPH3L
     Search ThermoFisher Antibodies for GOLPH3L
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GOLPH3L
     inGenious Targeting Laboratory - Custom generated mouse model solutions for GOLPH3L
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for GOLPH3L
    Customized:
     lentivirus for stable overexpression of GOLPH3L
     lentivirus expression plasmids for stable overexpression of GOLPH3L
     adenovirus for overexpression of GOLPH3L
     LSBio Antibodies in human, mouse, rat for GOLPH3L
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      GOLPH3L gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4