Aliases for GOLGA8F Gene
Aliases for GOLGA8F Gene
External Ids for GOLGA8F Gene
- HGNC: 32378
- Entrez Gene: 100132565
- Ensembl: ENSG00000153684
- UniProtKB: Q08AF8
Previous GeneCards Identifiers for GOLGA8F Gene
- GC15P026299
- GC15P020991
- GC15U900794
- GC15P028623
Summaries for GOLGA8F Gene
GeneCards Summary for GOLGA8F Gene
GOLGA8F (Golgin A8 Family Member F) is a Protein Coding gene. An important paralog of this gene is GOLGA8G.
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GOLGA8F Gene
Genomics for GOLGA8F Gene
Regulatory Elements for GOLGA8F Gene
Regulatory Element Products
Genomic Location for GOLGA8F Gene
- Chromosome:
- 15
- Start:
- 28,378,621 bp from pter
- End:
- 28,392,018 bp from pter
- Size:
- 13,398 bases
- Orientation:
- Plus strand
Genomic View for GOLGA8F Gene
Genes around GOLGA8F on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 15q13.1 by Ensembl
- 15q13.1 by Entrez Gene
- 15q13.1 by HGNC
GOLGA8F Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for GOLGA8F Gene
Proteins for GOLGA8F Gene
-
Protein details for GOLGA8F Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q08AF8-GOG8F_HUMAN
- Recommended name:
- Putative golgin subfamily A member 8F/8G
- Protein Accession:
- Q08AF8
- A4FTY1
- Q1A5X9
- Q8NDK0
Protein attributes for GOLGA8F Gene
- Size:
- 430 amino acids
- Molecular mass:
- 48405 Da
- Quaternary structure:
- No Data Available
Post-translational modifications for GOLGA8F Gene
No Post-translational modifications
Other Protein References for GOLGA8F Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- GeneTex Fbxl4 antibody for GOLGA8F
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for GOLGA8F
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- Search GeneTex for Proteins for GOLGA8F
No data available for DME Specific Peptides for GOLGA8F Gene
Domains & Families for GOLGA8F Gene
Graphical View of Domain Structure for InterPro Entry
Q08AF8- Family:
-
- Belongs to the GOLGA8 family.
No data available for Gene Families and Suggested Antigen Peptide Sequences for GOLGA8F Gene
Function for GOLGA8F Gene
Phenotypes for GOLGA8F Gene
- GenomeRNAi human phenotypes for GOLGA8F:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
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-
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miRNA Products
- Search ViGene Biosciences for GOLGA8F
Inhibitory RNA Products
- Origene siRNA and RNAi products in human, mouse, rat for GOLGA8F
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Clone Products
- GenScript: Custom all cDNA clones Services for GOLGA8F
- VectorBuilder custom plasmid, inducible vectors for GOLGA8F
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for GOLGA8F
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GOLGA8F Gene
Localization for GOLGA8F Gene
| Compartment | Confidence |
|---|---|
| nucleus | 3 |
| cytosol | 2 |
| golgi apparatus | 2 |
| extracellular | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005794 | Golgi apparatus | IEA | -- |
No data available for Subcellular locations from UniProtKB/Swiss-Prot for GOLGA8F Gene
Pathways & Interactions for GOLGA8F Gene
No Data Available
Interacting Proteins for GOLGA8F Gene
Selected Interacting proteins:
Q08AF8-GOG8F_HUMAN
ENSP00000454322
for GOLGA8F Gene via
IID
UniProtKB
STRING
No data available for Pathways by source and SIGNOR curated interactions for GOLGA8F Gene
Transcripts for GOLGA8F Gene
mRNA/cDNA for GOLGA8F Gene
- (3) REFSEQ mRNAs :
- (13) Additional mRNA sequences :
- (6) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for GOLGA8F Gene
miRNA Products
- Search ViGene Biosciences for GOLGA8F
Inhibitory RNA Products
- Origene siRNA and RNAi products in human, mouse, rat for GOLGA8F
- Browse OriGene Inhibitory RNA Products For GOLGA8F
- Search ViGene Biosciences for GOLGA8F
Clone Products
- GenScript: Custom all cDNA clones Services for GOLGA8F
- VectorBuilder custom plasmid, inducible vectors for GOLGA8F
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for GOLGA8F
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Expression for GOLGA8F Gene
mRNA differential expression in normal tissues according to GTEx for GOLGA8F Gene
This gene is overexpressed in Testis (x49.0).
NURSA nuclear receptor signaling pathways regulating expression of GOLGA8F Gene:
GOLGA8FSOURCE GeneReport for Unigene cluster for GOLGA8F Gene:
Hs.510812Primer Products
-
OriGene qPCR primer pairs for GOLGA8F
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GOLGA8F Gene
Orthologs for GOLGA8F Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | -- 35 |
|
ManyToMany | |
| cow (Bos Taurus) |
Mammalia | -- 35 |
|
OneToMany | |
| mouse (Mus musculus) |
Mammalia | Golga2 35 |
|
OneToMany | |
| dog (Canis familiaris) |
Mammalia | -- 35 |
|
OneToMany | |
| oppossum (Monodelphis domestica) |
Mammalia | -- 35 |
|
OneToMany | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | -- 35 |
|
OneToMany | |
| chicken (Gallus gallus) |
Aves | -- 35 |
|
OneToMany | |
| lizard (Anolis carolinensis) |
Reptilia | -- 35 |
|
OneToMany | |
| zebrafish (Danio rerio) |
Actinopterygii | golga2 35 |
|
OneToMany |
- Species where no ortholog for GOLGA8F was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for GOLGA8F Gene
Paralogs for GOLGA8F Gene
(36) SIMAP similar genes for GOLGA8F Gene using alignment to 2 proteins:
- GOLGA8G
- GOLGA8DP
- GOLGA8S
- GOLGA8I
- GOLGA8T
- GOLGA8Q
- GOLGA8M
- GOLGA8H
- GOLGA8O
- GOLGA8R
- GOLGA8CP
- GOLGA8J
- GOLGA8K
- DKFZp564E0216
- GOLGA8N
- DKFZp434J052
- GOLGA8B
- GOLGA8A
- LOC643699
- GOLGA6L4
- GOLGA6D
- GOLGA6C
- GOLGA6B
- GOLGA6A
- GOLGA2L1
- WUGSC
- GOLGA6L10
- GOLGA6
- GOLGA6L18
- GOLGA6L3
- GOLGA6L9
- GOLGA6L19
- GOLGA2LY
- DKFZp686K0319
- GOLGA6L20
- GOLGA6L2
Pseudogenes.org Pseudogenes for GOLGA8F Gene
Variants for GOLGA8F Gene
| SNP ID | Clin | Chr 15 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs201542804 | -- | 28,376,649(+) | TTGTT(-/A)AAAAA | upstream-variant-2KB |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv2491n100 | CNV | gain | 25217958 |
| dgv2492n100 | CNV | gain | 25217958 |
| dgv725e212 | CNV | loss | 25503493 |
| esv22824 | CNV | gain+loss | 19812545 |
| esv26019 | CNV | gain+loss | 19812545 |
| esv2674813 | CNV | deletion | 23128226 |
| esv2760021 | CNV | gain+loss | 17122850 |
| nsv1052131 | CNV | gain | 25217958 |
| nsv1075896 | CNV | duplication | 25765185 |
| nsv1118554 | CNV | duplication | 24896259 |
| nsv1141260 | CNV | duplication | 24896259 |
| nsv1148060 | CNV | duplication | 26484159 |
| nsv1148560 | OTHER | inversion | 26484159 |
| nsv1150469 | CNV | duplication | 26484159 |
| nsv1152851 | CNV | duplication | 26484159 |
| nsv428299 | CNV | loss | 18775914 |
| nsv433431 | CNV | gain | 18776910 |
| nsv469883 | CNV | gain | 16826518 |
| nsv568662 | CNV | gain | 21841781 |
| nsv832941 | CNV | gain+loss | 17160897 |
| nsv974540 | CNV | duplication | 23825009 |
| nsv976906 | CNV | duplication | 23825009 |
| nsv977790 | CNV | duplication | 23825009 |
Gene Damage Index Score:
4.12;
61.25% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for GOLGA8F Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- GOLGA8F
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GOLGA8F Gene
Disorders for GOLGA8F Gene
Relevant External Links for GOLGA8F
- Atlas of Genetics and Cytogenetics in Oncology and Haematology:
- GOLGA8F
No disorders were found for GOLGA8F Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GOLGA8F Gene
Publications for GOLGA8F Gene
- Genomic analysis of the chromosome 15q11-q13 Prader-Willi syndrome region and characterization of transcripts for GOLGA8E and WHCD1L1 from the proximal breakpoint region. (PMID: 18226259) Jiang Y.-H. … Beaudet A.L. (BMC Genomics 2008) 3 4 64
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
- A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
- Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns. (PMID: 17672918) Szafranski K. … Platzer M. (Genome Biol. 2007) 3 64
Products for GOLGA8F Gene
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- GeneTex Fbxl4 antibody for GOLGA8F
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- Cyagen custom Knockout/knockin (KOKI) mouse models for GOLGA8F
- VectorBuilder custom plasmid, inducible vectors for GOLGA8F
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for GOLGA8F
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for GOLGA8F Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus Biologicals
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
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- (86) GenomeRNAi
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- (88) miRTarBase
- (89) MalaCards
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- (96) MaxQB
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- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
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- (122) diseasecard
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- (128) Genetics Home Reference
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- (133) NCBI Bookshelf
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- (135) Gene Damage Index
- (136) ViGene Biosciences
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- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
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- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer
- (156) abm
- (157) CrownBio