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GOLGA8F Gene(Pseudogene)

Golgin A8 Family Member F

GCID:
GC15P028378
GIFtS:
29
Genes Participants
UDN Logo

Aliases for GOLGA8F Gene

Aliases for GOLGA8F Gene

  • Golgin A8 Family Member F 2 3 5
  • Golgi Autoantigen, Golgin Subfamily A, 8F 2
  • Golgin A8 Family, Member F 2
  • GOLGA8F GOLGA8G 4

External Ids for GOLGA8F Gene

Previous GeneCards Identifiers for GOLGA8F Gene

  • GC15P026299
  • GC15P020991
  • GC15U900794
  • GC15P028623

Summaries for GOLGA8F Gene

GeneCards Summary for GOLGA8F Gene

GOLGA8F (Golgin A8 Family Member F) is a Pseudogene. An important paralog of this gene is GOLGA8G.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GOLGA8F Gene

Genomics for GOLGA8F Gene

Products:

  1. Regulatory Element

Regulatory Elements for GOLGA8F Gene


Transcription factor binding sites by QIAGEN in the GOLGA8F gene promoter:

Genomic Location for GOLGA8F Gene

Chromosome:
15
Start:
28,378,621 bp from pter
End:
28,392,018 bp from pter
Size:
13,398 bases
Orientation:
Plus strand

Genomic View for GOLGA8F Gene

Genes around GOLGA8F on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GOLGA8F Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GOLGA8F Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for GOLGA8F Gene

Proteins for GOLGA8F Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for GOLGA8F Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q08AF8-GOG8F_HUMAN
    Recommended name:
    Putative golgin subfamily A member 8F/8G
    Protein Accession:
    Q08AF8
    Secondary Accessions:
    • A4FTY1
    • Q1A5X9
    • Q8NDK0

    Protein attributes for GOLGA8F Gene

    Size:
    430 amino acids
    Molecular mass:
    48405 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for GOLGA8F Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for GOLGA8F Gene

Proteomics data for GOLGA8F Gene at MOPED

Post-translational modifications for GOLGA8F Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GOLGA8F Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for GOLGA8F Gene

Domains & Families for GOLGA8F Gene

Protein Domains for GOLGA8F Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q08AF8

UniProtKB/Swiss-Prot:

GOG8F_HUMAN :
  • Belongs to the GOLGA8 family.
Family:
  • Belongs to the GOLGA8 family.
genes like me logo Genes that share domains with GOLGA8F: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for GOLGA8F Gene

Function for GOLGA8F Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Phenotypes for GOLGA8F Gene

GenomeRNAi human phenotypes for GOLGA8F:
genes like me logo Genes that share phenotypes with GOLGA8F: view

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GOLGA8F Gene

Localization for GOLGA8F Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for GOLGA8F Gene COMPARTMENTS Subcellular localization image for GOLGA8F gene
Compartment Confidence
nucleus 3
cytosol 2
golgi apparatus 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for GOLGA8F Gene

Pathways & Interactions for GOLGA8F Gene

SuperPathways for GOLGA8F Gene

PathCards logoMore details on SuperPathways for GOLGA8F
No Data Available

Gene Ontology (GO) - Biological Process for GOLGA8F Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GOLGA8F Gene

Drugs & Compounds for GOLGA8F Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for GOLGA8F Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

mRNA/cDNA for GOLGA8F Gene

(2) REFSEQ mRNAs :
(13) Additional mRNA sequences :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for GOLGA8F Gene

Golgin A8 family, member F:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for GOLGA8F Gene

No ASD Table

Relevant External Links for GOLGA8F Gene

GeneLoc Exon Structure for
GOLGA8F
ECgene alternative splicing isoforms for
GOLGA8F

Expression for GOLGA8F Gene

Products:

  1. Primer

mRNA expression in normal human tissues for GOLGA8F Gene

mRNA expression in normal human tissues for GOLGA8F Gene
mRNA expression by BioGPS for GOLGA8F GenemRNA expression by GTEx for GOLGA8F Gene

mRNA differential expression in normal tissues according to GTEx for GOLGA8F Gene

This gene is overexpressed in Testis (x49.0).

SOURCE GeneReport for Unigene cluster for GOLGA8F Gene Hs.510812

genes like me logo Genes that share expression patterns with GOLGA8F: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for GOLGA8F Gene

Orthologs for GOLGA8F Gene

This gene was present in the common ancestor of chordates.

Orthologs for GOLGA8F Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
 Mammalia -- 36
  • 31 (a)
 OneToMany
dog
(Canis familiaris)
 Mammalia -- 36
  • 28 (a)
 OneToMany
oppossum
(Monodelphis domestica)
 Mammalia -- 36
  • 27 (a)
 OneToMany
mouse
(Mus musculus)
 Mammalia Golga2 36
  • 30 (a)
 OneToMany
platypus
(Ornithorhynchus anatinus)
 Mammalia -- 36
  • 27 (a)
 OneToMany
chimpanzee
(Pan troglodytes)
 Mammalia -- 36
  • 67 (a)
 ManyToMany
chicken
(Gallus gallus)
 Aves -- 36
  • 24 (a)
 OneToMany
lizard
(Anolis carolinensis)
 Reptilia -- 36
  • 23 (a)
 OneToMany
zebrafish
(Danio rerio)
 Actinopterygii golga2 36
  • 18 (a)
 OneToMany
Species with no ortholog for GOLGA8F:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GOLGA8F Gene

ENSEMBL:
Gene Tree for GOLGA8F (if available)
TreeFam:
Gene Tree for GOLGA8F (if available)

Paralogs for GOLGA8F Gene

Paralogs for GOLGA8F Gene

(36) SIMAP similar genes for GOLGA8F Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for GOLGA8F Gene

genes like me logo Genes that share paralogs with GOLGA8F: view

Variants for GOLGA8F Gene

Sequence variations from dbSNP and Humsavar for GOLGA8F Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs374699883 -- 28,385,067(+) TTTTC(-/T)TTTTT intron-variant
rs201542804 -- 28,376,649(+) TTGTT(-/A)AAAAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for GOLGA8F Gene

Variant ID Type Subtype PubMed ID
nsv428299 CNV Loss 18775914
dgv712e1 CNV Complex 17122850
dgv713e1 CNV Complex 17122850
esv2674813 CNV Deletion 23128226
nsv469883 CNV Gain 16826518
esv22824 CNV Gain+Loss 19812545
nsv433431 CNV Gain 18776910
nsv903743 CNV Gain 21882294
nsv832941 CNV Gain+Loss 17160897
esv26019 CNV Gain+Loss 19812545

Variation tolerance for GOLGA8F Gene

Gene Damage Index Score: 4.12; 61.25% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for GOLGA8F Gene

Disorders for GOLGA8F Gene

Relevant External Links for GOLGA8F

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
GOLGA8F

No disorders were found for GOLGA8F Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GOLGA8F Gene

Publications for GOLGA8F Gene

  1. Genomic analysis of the chromosome 15q11-q13 Prader-Willi syndrome region and characterization of transcripts for GOLGA8E and WHCD1L1 from the proximal breakpoint region. (PMID: 18226259) Jiang Y.-H. … Beaudet A.L. (BMC Genomics 2008) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns. (PMID: 17672918) Szafranski K. … Platzer M. (Genome Biol. 2007) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for GOLGA8F Gene

Sources for GOLGA8F Gene

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