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GOLGA8F Gene(Protein Coding)

Golgin A8 Family Member F

GCID:
GC15P028378
GIFtS:
29
Genes Participants
UDN Logo

Aliases for GOLGA8F Gene

Aliases for GOLGA8F Gene

  • Golgin A8 Family Member F 2 3 5
  • Golgi Autoantigen, Golgin Subfamily A, 8F 2
  • Golgin A8 Family, Member F 2
  • GOLGA8F GOLGA8G 4

External Ids for GOLGA8F Gene

Previous GeneCards Identifiers for GOLGA8F Gene

  • GC15P026299
  • GC15P020991
  • GC15U900794
  • GC15P028623

Summaries for GOLGA8F Gene

GeneCards Summary for GOLGA8F Gene

GOLGA8F (Golgin A8 Family Member F) is a Protein Coding gene. An important paralog of this gene is GOLGA8G.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GOLGA8F Gene

Genomics for GOLGA8F Gene

Products:

  1. Regulatory Element

Regulatory Elements for GOLGA8F Gene


Transcription factor binding sites by QIAGEN in the GOLGA8F gene promoter:

Genomic Location for GOLGA8F Gene

Chromosome:
15
Start:
28,378,621 bp from pter
End:
28,392,018 bp from pter
Size:
13,398 bases
Orientation:
Plus strand

Genomic View for GOLGA8F Gene

Genes around GOLGA8F on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GOLGA8F Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GOLGA8F Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for GOLGA8F Gene

Proteins for GOLGA8F Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for GOLGA8F Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q08AF8-GOG8F_HUMAN
    Recommended name:
    Putative golgin subfamily A member 8F/8G
    Protein Accession:
    Q08AF8
    Secondary Accessions:
    • A4FTY1
    • Q1A5X9
    • Q8NDK0

    Protein attributes for GOLGA8F Gene

    Size:
    430 amino acids
    Molecular mass:
    48405 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for GOLGA8F Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for GOLGA8F Gene

Post-translational modifications for GOLGA8F Gene

No Post-translational modifications

Other Protein References for GOLGA8F Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GOLGA8F Gene

Domains & Families for GOLGA8F Gene

Protein Domains for GOLGA8F Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q08AF8

UniProtKB/Swiss-Prot:

GOG8F_HUMAN :
  • Belongs to the GOLGA8 family.
Family:
  • Belongs to the GOLGA8 family.
genes like me logo Genes that share domains with GOLGA8F: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for GOLGA8F Gene

Function for GOLGA8F Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Phenotypes for GOLGA8F Gene

GenomeRNAi human phenotypes for GOLGA8F:
genes like me logo Genes that share phenotypes with GOLGA8F: view

Animal Model Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GOLGA8F Gene

Localization for GOLGA8F Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GOLGA8F gene
Compartment Confidence
nucleus 3
cytosol 2
golgi apparatus 2
extracellular 1

Gene Ontology (GO) - Cellular Components for GOLGA8F Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005794 Golgi apparatus IEA --
genes like me logo Genes that share ontologies with GOLGA8F: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for GOLGA8F Gene

Pathways & Interactions for GOLGA8F Gene

SuperPathways for GOLGA8F Gene

PathCards logo More details on SuperPathways for GOLGA8F
No Data Available

Gene Ontology (GO) - Biological Process for GOLGA8F Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GOLGA8F Gene

Drugs & Compounds for GOLGA8F Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for GOLGA8F Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for GOLGA8F Gene

(3) REFSEQ mRNAs :
(13) Additional mRNA sequences :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for GOLGA8F Gene

Golgin A8 family, member F:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for GOLGA8F Gene

No ASD Table

Relevant External Links for GOLGA8F Gene

GeneLoc Exon Structure for
GOLGA8F
ECgene alternative splicing isoforms for
GOLGA8F

Expression for GOLGA8F Gene

Products:

  1. Primer

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for GOLGA8F Gene

mRNA expression in normal human tissues for GOLGA8F Gene
mRNA expression by BioGPS for GOLGA8F GenemRNA expression by GTEx for GOLGA8F Gene

mRNA differential expression in normal tissues according to GTEx for GOLGA8F Gene

This gene is overexpressed in Testis (x49.0).

NURSA nuclear receptor signaling pathways regulating expression of GOLGA8F Gene:

GOLGA8F

SOURCE GeneReport for Unigene cluster for GOLGA8F Gene:

Hs.510812
genes like me logo Genes that share expression patterns with GOLGA8F: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GOLGA8F Gene

Orthologs for GOLGA8F Gene

This gene was present in the common ancestor of chordates.

Orthologs for GOLGA8F Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
 Mammalia -- 35
  • 67 (a)
 ManyToMany
cow
(Bos Taurus)
 Mammalia -- 35
  • 31 (a)
 OneToMany
mouse
(Mus musculus)
 Mammalia Golga2 35
  • 30 (a)
 OneToMany
dog
(Canis familiaris)
 Mammalia -- 35
  • 28 (a)
 OneToMany
oppossum
(Monodelphis domestica)
 Mammalia -- 35
  • 27 (a)
 OneToMany
platypus
(Ornithorhynchus anatinus)
 Mammalia -- 35
  • 27 (a)
 OneToMany
chicken
(Gallus gallus)
 Aves -- 35
  • 24 (a)
 OneToMany
lizard
(Anolis carolinensis)
 Reptilia -- 35
  • 23 (a)
 OneToMany
zebrafish
(Danio rerio)
 Actinopterygii golga2 35
  • 18 (a)
 OneToMany
Species where no ortholog for GOLGA8F was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GOLGA8F Gene

ENSEMBL:
Gene Tree for GOLGA8F (if available)
TreeFam:
Gene Tree for GOLGA8F (if available)

Paralogs for GOLGA8F Gene

Paralogs for GOLGA8F Gene

(36) SIMAP similar genes for GOLGA8F Gene using alignment to 2 proteins:

Pseudogenes.org Pseudogenes for GOLGA8F Gene

genes like me logo Genes that share paralogs with GOLGA8F: view

Variants for GOLGA8F Gene

Sequence variations from dbSNP and Humsavar for GOLGA8F Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs201542804 -- 28,376,649(+) TTGTT(-/A)AAAAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for GOLGA8F Gene

Variant ID Type Subtype PubMed ID
dgv2491n100 CNV gain 25217958
dgv2492n100 CNV gain 25217958
dgv725e212 CNV loss 25503493
esv22824 CNV gain+loss 19812545
esv26019 CNV gain+loss 19812545
esv2674813 CNV deletion 23128226
esv2760021 CNV gain+loss 17122850
nsv1052131 CNV gain 25217958
nsv1075896 CNV duplication 25765185
nsv1118554 CNV duplication 24896259
nsv1141260 CNV duplication 24896259
nsv1148060 CNV duplication 26484159
nsv1148560 OTHER inversion 26484159
nsv1150469 CNV duplication 26484159
nsv1152851 CNV duplication 26484159
nsv428299 CNV loss 18775914
nsv433431 CNV gain 18776910
nsv469883 CNV gain 16826518
nsv568662 CNV gain 21841781
nsv832941 CNV gain+loss 17160897
nsv974540 CNV duplication 23825009
nsv976906 CNV duplication 23825009
nsv977790 CNV duplication 23825009

Variation tolerance for GOLGA8F Gene

Gene Damage Index Score: 4.12; 61.25% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for GOLGA8F Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GOLGA8F

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GOLGA8F Gene

Disorders for GOLGA8F Gene

Relevant External Links for GOLGA8F

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
GOLGA8F

No disorders were found for GOLGA8F Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GOLGA8F Gene

Publications for GOLGA8F Gene

  1. Genomic analysis of the chromosome 15q11-q13 Prader-Willi syndrome region and characterization of transcripts for GOLGA8E and WHCD1L1 from the proximal breakpoint region. (PMID: 18226259) Jiang Y.-H. … Beaudet A.L. (BMC Genomics 2008) 3 4 64
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
  5. Violating the splicing rules: TG dinucleotides function as alternative 3' splice sites in U2-dependent introns. (PMID: 17672918) Szafranski K. … Platzer M. (Genome Biol. 2007) 3 64

Products for GOLGA8F Gene

Sources for GOLGA8F Gene

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