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Aliases for GOLGA8B Gene

Aliases for GOLGA8B Gene

  • Golgin A8 Family Member B 2 3 5
  • Golgi Autoantigen, Golgin Subfamily A, 8B 2 3
  • Golgin A8 Family, Member B 2 3
  • Golgin-67 3 4
  • GOLGA5 3

External Ids for GOLGA8B Gene

Previous GeneCards Identifiers for GOLGA8B Gene

  • GC15M032460
  • GC15M032605
  • GC15M034817

Summaries for GOLGA8B Gene

GeneCards Summary for GOLGA8B Gene

GOLGA8B (Golgin A8 Family Member B) is a Protein Coding gene. An important paralog of this gene is GOLGA8G.

UniProtKB/Swiss-Prot for GOLGA8B Gene

  • May be involved in maintaining Golgi structure.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GOLGA8B Gene

Genomics for GOLGA8B Gene

Regulatory Elements for GOLGA8B Gene

Enhancers for GOLGA8B Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around GOLGA8B on UCSC Golden Path with GeneCards custom track

Promoters for GOLGA8B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around GOLGA8B on UCSC Golden Path with GeneCards custom track

Genomic Location for GOLGA8B Gene

34,525,207 bp from pter
34,588,503 bp from pter
63,297 bases
Minus strand

Genomic View for GOLGA8B Gene

Genes around GOLGA8B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GOLGA8B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GOLGA8B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GOLGA8B Gene

Proteins for GOLGA8B Gene

  • Protein details for GOLGA8B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Golgin subfamily A member 8B
    Protein Accession:
    Secondary Accessions:
    • A6NLZ2
    • O94937
    • Q2M3S9
    • Q9NZG8
    • Q9NZW0
    • Q9NZW3

    Protein attributes for GOLGA8B Gene

    603 amino acids
    Molecular mass:
    67278 Da
    Quaternary structure:
    No Data Available
    • Antibodies against GM88 are present in serum from a patient with Sjoegren syndrome. Sera from patients with Sjoegren syndrome often contain antibodies that react with normal components of the Golgi complex.

    Alternative splice isoforms for GOLGA8B Gene


neXtProt entry for GOLGA8B Gene

Proteomics data for GOLGA8B Gene at MOPED

Post-translational modifications for GOLGA8B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GOLGA8B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GOLGA8B Gene

Domains & Families for GOLGA8B Gene

Protein Domains for GOLGA8B Gene


Suggested Antigen Peptide Sequences for GOLGA8B Gene

Graphical View of Domain Structure for InterPro Entry



  • Extended rod-like protein with coiled-coil domains.
  • Belongs to the GOLGA8 family.
  • Extended rod-like protein with coiled-coil domains.
  • Belongs to the GOLGA8 family.
genes like me logo Genes that share domains with GOLGA8B: view

No data available for Gene Families for GOLGA8B Gene

Function for GOLGA8B Gene

Molecular function for GOLGA8B Gene

UniProtKB/Swiss-Prot Function:
May be involved in maintaining Golgi structure.

Phenotypes for GOLGA8B Gene

GenomeRNAi human phenotypes for GOLGA8B:
genes like me logo Genes that share phenotypes with GOLGA8B: view

Animal Model Products

CRISPR Products

miRNA for GOLGA8B Gene

miRTarBase miRNAs that target GOLGA8B

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GOLGA8B Gene

Localization for GOLGA8B Gene

Subcellular locations from UniProtKB/Swiss-Prot for GOLGA8B Gene

Golgi apparatus, Golgi stack membrane; Peripheral membrane protein.

Subcellular locations from

Jensen Localization Image for GOLGA8B Gene COMPARTMENTS Subcellular localization image for GOLGA8B gene
Compartment Confidence
golgi apparatus 5
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for GOLGA8B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA --
GO:0032580 Golgi cisterna membrane IEA --
genes like me logo Genes that share ontologies with GOLGA8B: view

Pathways & Interactions for GOLGA8B Gene

SuperPathways for GOLGA8B Gene

No Data Available

Interacting Proteins for GOLGA8B Gene

Gene Ontology (GO) - Biological Process for GOLGA8B Gene


No data available for Pathways by source and SIGNOR curated interactions for GOLGA8B Gene

Drugs & Compounds for GOLGA8B Gene

No Compound Related Data Available

Transcripts for GOLGA8B Gene

mRNA/cDNA for GOLGA8B Gene

(6) REFSEQ mRNAs :
(7) Additional mRNA sequences :
(1) Selected AceView cDNA sequences:
(11) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for GOLGA8B Gene

Golgin A8 family, member B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for GOLGA8B Gene

No ASD Table

Relevant External Links for GOLGA8B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for GOLGA8B Gene

mRNA expression in normal human tissues for GOLGA8B Gene

mRNA differential expression in normal tissues according to GTEx for GOLGA8B Gene

This gene is overexpressed in Pancreas (x5.6).

SOURCE GeneReport for Unigene cluster for GOLGA8B Gene Hs.720151

mRNA Expression by UniProt/SwissProt for GOLGA8B Gene

Tissue specificity: Highly expressed in brain, heart and kidney. Detected at lower levels in liver, thymus, spleen, lung and peripheral blood leukocytes.
genes like me logo Genes that share expression patterns with GOLGA8B: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for GOLGA8B Gene

Orthologs for GOLGA8B Gene

This gene was present in the common ancestor of chordates.

Orthologs for GOLGA8B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia -- 36
  • 26 (a)
(Canis familiaris)
Mammalia -- 36
  • 24 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 23 (a)
(Mus musculus)
Mammalia Golga2 36
  • 25 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 30 (a)
(Pan troglodytes)
Mammalia -- 36
  • 96 (a)
(Gallus gallus)
Aves -- 36
  • 21 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 21 (a)
(Danio rerio)
Actinopterygii golga2 36
  • 17 (a)
Species with no ortholog for GOLGA8B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GOLGA8B Gene

Gene Tree for GOLGA8B (if available)
Gene Tree for GOLGA8B (if available)

Paralogs for GOLGA8B Gene Pseudogenes for GOLGA8B Gene

genes like me logo Genes that share paralogs with GOLGA8B: view

Variants for GOLGA8B Gene

Sequence variations from dbSNP and Humsavar for GOLGA8B Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs3538 -- 34,525,306(+) TTATC(A/G)CATTA nc-transcript-variant, utr-variant-3-prime
rs168391 -- 34,563,836(-) TATAG(A/G)AATAC intron-variant
rs173227 -- 34,544,652(+) TGGTA(A/G)GCATA intron-variant
rs173259 -- 34,565,130(-) GAGAA(A/C)TGGAT intron-variant
rs187032 -- 34,564,586(-) AAATG(C/G)AAAGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for GOLGA8B Gene

Variant ID Type Subtype PubMed ID
esv33337 CNV Gain+Loss 17666407
dgv730e1 CNV Complex 17122850
dgv731e1 CNV Complex 17122850
nsv428303 CNV Gain 18775914
nsv471682 CNV Gain+Loss 15918152
nsv1485 CNV Loss 18451855
nsv517751 CNV Gain+Loss 19592680
nsv827290 CNV Loss 20364138
dgv2339n71 CNV Gain+Loss 21882294
dgv2340n71 CNV Gain 21882294
dgv733e1 CNV Complex 17122850
esv27955 CNV Gain+Loss 19812545
nsv819187 CNV Gain 19587683
dgv338e201 CNV Deletion 23290073
esv992827 CNV Gain 20482838
dgv2341n71 CNV Loss 21882294
nsv9241 CNV Gain+Loss 18304495
dgv2344n71 CNV Gain+Loss 21882294
nsv110 CNV Loss 15895083
dgv2346n71 CNV Loss 21882294
nsv821682 CNV Loss 15273396
nsv904029 CNV Gain+Loss 21882294
nsv442698 CNV CNV 18776908
dgv734e1 CNV Complex 17122850
dgv735e1 CNV Complex 17122850
nsv820603 CNV Deletion 20802225
nsv827291 CNV Gain 20364138
dgv2347n71 CNV Loss 21882294
dgv313n27 CNV Loss 19166990
dgv314n27 CNV Gain 19166990
dgv2349n71 CNV Gain+Loss 21882294
dgv2350n71 CNV Loss 21882294
dgv2351n71 CNV Gain 21882294
nsv469685 CNV Loss 16826518
dgv2354n71 CNV Loss 21882294
essv985 CNV CNV 17122850
dgv2355n71 CNV Loss 21882294
esv2751533 CNV Loss 17911159
nsv827294 CNV Loss 20364138
nsv510658 CNV Loss 20534489
nsv832965 CNV Loss 17160897
esv2663546 CNV Deletion 23128226
nsv820789 CNV Deletion 20802225
nsv832966 CNV Loss 17160897
esv2281816 CNV Deletion 18987734

Variation tolerance for GOLGA8B Gene

Gene Damage Index Score: 8.97; 87.31% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for GOLGA8B Gene

Disorders for GOLGA8B Gene

Relevant External Links for GOLGA8B

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for GOLGA8B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GOLGA8B Gene

Publications for GOLGA8B Gene

  1. A genome-wide association study identifies a susceptibility locus for refractive errors and myopia at 15q14. (PMID: 20835239) Solouki A.M. … Klaver C.C. (Nat. Genet. 2010) 3 48 67
  2. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody M.C. … Nusbaum C. (Nature 2006) 3
  3. A germline-specific class of small RNAs binds mammalian Piwi proteins. (PMID: 16751776) Girard A. … Carmell M.A. (Nature 2006) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3

Products for GOLGA8B Gene

Sources for GOLGA8B Gene