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Aliases for GOLGA6D Gene

Aliases for GOLGA6D Gene

  • Golgin A6 Family Member D 2 3 5
  • Golgi Autoantigen, Golgin Subfamily A, 6D 2
  • Golgin A6 Family, Member D 2

External Ids for GOLGA6D Gene

Previous GeneCards Identifiers for GOLGA6D Gene

  • GC15P073363
  • GC15P075577
  • GC15P052343
  • GC15P075259

Summaries for GOLGA6D Gene

GeneCards Summary for GOLGA6D Gene

GOLGA6D (Golgin A6 Family Member D) is a Protein Coding gene. An important paralog of this gene is GOLGA6C.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GOLGA6D Gene

Genomics for GOLGA6D Gene

Regulatory Elements for GOLGA6D Gene

Enhancers for GOLGA6D Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15G075274 0.8 Ensembl 0.4 -8.4 -8395 0.9 GTF2F1 HDGF CTCF PKNOX1 NFXL1 GLI4 RAD21 ZNF121 ZNF316 ELK1 GOLGA6D RN7SL489P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around GOLGA6D on UCSC Golden Path with GeneCards custom track

Genomic Location for GOLGA6D Gene

Chromosome:
15
Start:
75,282,835 bp from pter
End:
75,295,807 bp from pter
Size:
12,973 bases
Orientation:
Plus strand

Genomic View for GOLGA6D Gene

Genes around GOLGA6D on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GOLGA6D Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GOLGA6D Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GOLGA6D Gene

Proteins for GOLGA6D Gene

  • Protein details for GOLGA6D Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0CG33-GOG6D_HUMAN
    Recommended name:
    Golgin subfamily A member 6D
    Protein Accession:
    P0CG33

    Protein attributes for GOLGA6D Gene

    Size:
    693 amino acids
    Molecular mass:
    79896 Da
    Quaternary structure:
    No Data Available

neXtProt entry for GOLGA6D Gene

Post-translational modifications for GOLGA6D Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GOLGA6D Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GOLGA6D Gene

Domains & Families for GOLGA6D Gene

Protein Domains for GOLGA6D Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for GOLGA6D Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P0CG33

UniProtKB/Swiss-Prot:

GOG6D_HUMAN :
  • Belongs to the GOLGA6 family.
Family:
  • Belongs to the GOLGA6 family.
genes like me logo Genes that share domains with GOLGA6D: view

No data available for Gene Families for GOLGA6D Gene

Function for GOLGA6D Gene

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GOLGA6D Gene

Localization for GOLGA6D Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for GOLGA6D gene
Compartment Confidence
nucleus 3
golgi apparatus 3
cytosol 2
mitochondrion 1

Gene Ontology (GO) - Cellular Components for GOLGA6D Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005794 Golgi apparatus IEA --
genes like me logo Genes that share ontologies with GOLGA6D: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for GOLGA6D Gene

Pathways & Interactions for GOLGA6D Gene

SuperPathways for GOLGA6D Gene

No Data Available

Interacting Proteins for GOLGA6D Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://version10.5.string-db.org/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000391085%0d%0a9606.ENSP00000440586%0d%0a
Selected Interacting proteins: ENSP00000391085 for GOLGA6D Gene via STRING

Symbol External ID(s) Details
--

Gene Ontology (GO) - Biological Process for GOLGA6D Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GOLGA6D Gene

Drugs & Compounds for GOLGA6D Gene

No Compound Related Data Available

Transcripts for GOLGA6D Gene

mRNA/cDNA for GOLGA6D Gene

(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for GOLGA6D Gene

No ASD Table

Relevant External Links for GOLGA6D Gene

GeneLoc Exon Structure for
GOLGA6D
ECgene alternative splicing isoforms for
GOLGA6D

Expression for GOLGA6D Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for GOLGA6D Gene

mRNA differential expression in normal tissues according to GTEx for GOLGA6D Gene

This gene is overexpressed in Testis (x46.8).

NURSA nuclear receptor signaling pathways regulating expression of GOLGA6D Gene:

GOLGA6D
genes like me logo Genes that share expression patterns with GOLGA6D: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GOLGA6D Gene

Orthologs for GOLGA6D Gene

This gene was present in the common ancestor of chordates.

Orthologs for GOLGA6D Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 35
  • 94 (a)
ManyToMany
-- 35
  • 93 (a)
ManyToMany
-- 35
  • 92 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 35
  • 33 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 33 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Golga2 35
  • 32 (a)
OneToMany
dog
(Canis familiaris)
Mammalia -- 35
  • 31 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 30 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 35
  • 27 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 35
  • 26 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii golga2 35
  • 21 (a)
OneToMany
Species where no ortholog for GOLGA6D was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GOLGA6D Gene

ENSEMBL:
Gene Tree for GOLGA6D (if available)
TreeFam:
Gene Tree for GOLGA6D (if available)

Paralogs for GOLGA6D Gene

Variants for GOLGA6D Gene

Sequence variations from dbSNP and Humsavar for GOLGA6D Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs1002855553 -- 75,295,910(+) TTATG(C/T)AACTT downstream-variant-500B
rs1002886623 -- 75,295,672(+) GGAGC(-/T)TTCTT utr-variant-3-prime
rs1004710568 -- 75,295,945(+) ATCTA(A/C)TGTTT downstream-variant-500B
rs1005336747 -- 75,296,115(+) GAGTG(A/G)ATTAT downstream-variant-500B
rs1005928488 -- 75,294,129(+) TGCAA(C/G)AGTTG reference, missense

Structural Variations from Database of Genomic Variants (DGV) for GOLGA6D Gene

Variant ID Type Subtype PubMed ID
dgv1242n106 CNV duplication 24896259
dgv2621n100 CNV gain 25217958
esv22004 CNV gain 19812545
esv3334067 CNV duplication 20981092
esv3364343 CNV duplication 20981092
esv3416661 CNV duplication 20981092
esv996044 CNV gain 20482838
nsv1151179 CNV duplication 26484159
nsv1613 CNV deletion 18451855
nsv498851 CNV loss 21111241
nsv821359 CNV duplication 20802225
nsv833056 CNV gain 17160897
nsv9277 CNV loss 18304495
nsv977736 CNV duplication 23825009

Variation tolerance for GOLGA6D Gene

Gene Damage Index Score: 3.52; 55.56% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for GOLGA6D Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GOLGA6D

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GOLGA6D Gene

Disorders for GOLGA6D Gene

Relevant External Links for GOLGA6D

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
GOLGA6D

No disorders were found for GOLGA6D Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GOLGA6D Gene

Publications for GOLGA6D Gene

  1. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody M.C. … Nusbaum C. (Nature 2006) 3 4 64

Products for GOLGA6D Gene

Sources for GOLGA6D Gene

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