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Aliases for GOLGA6B Gene

Aliases for GOLGA6B Gene

  • Golgin A6 Family, Member B 2 3
  • Golgi Autoantigen, Golgin Subfamily A, 6B 2 3
  • GOLGA 3 4
  • Putative Golgin Subfamily A Member 6D 3
  • Golgin Subfamily A Member 6B 3
  • Golgin-Like Protein 3
  • GOLGA6D 3

External Ids for GOLGA6B Gene

Previous GeneCards Identifiers for GOLGA6B Gene

  • GC15P070737
  • GC15P072947
  • GC15P049778

Summaries for GOLGA6B Gene

Entrez Gene Summary for GOLGA6B Gene

  • This gene is found in a large, low copy repeat sequence or duplicon that is found in multiple copies, which are greater than 90% similar, on chromosome 15. Duplicons are associated with deletions, inversions and other chromosomal rearrangements that underlie genomic disease. This gene is a member of the golgin gene family, whose protein products localize to the Golgi apparatus. The majority of the related gene copies are thought to be transcribed pseudogenes. It is not known whether this gene is a pseudogene or if it encodes a golgin protein. [provided by RefSeq, Jul 2008]

GeneCards Summary for GOLGA6B Gene

GOLGA6B (Golgin A6 Family, Member B) is a Protein Coding gene. An important paralog of this gene is GOLGA8G.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GOLGA6B Gene

Genomics for GOLGA6B Gene

Regulatory Elements for GOLGA6B Gene

Genomic Location for GOLGA6B Gene

72,608,556 bp from pter
72,667,397 bp from pter
58,842 bases
Plus strand

Genomic View for GOLGA6B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for GOLGA6B Gene

Proteins for GOLGA6B Gene

  • Protein details for GOLGA6B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Putative golgin subfamily A member 6B
    Protein Accession:
    Secondary Accessions:
    • A8MYY7

    Protein attributes for GOLGA6B Gene

    693 amino acids
    Molecular mass:
    79913 Da
    Quaternary structure:
    No Data Available

neXtProt entry for GOLGA6B Gene

Proteomics data for GOLGA6B Gene at MOPED

Post-translational modifications for GOLGA6B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GOLGA6B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GOLGA6B Gene

Domains & Families for GOLGA6B Gene

Protein Domains for GOLGA6B Gene


Suggested Antigen Peptide Sequences for GOLGA6B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the GOLGA6 family.
  • Belongs to the GOLGA6 family.
genes like me logo Genes that share domains with GOLGA6B: view

No data available for Gene Families for GOLGA6B Gene

Function for GOLGA6B Gene

Phenotypes for GOLGA6B Gene

GenomeRNAi human phenotypes for GOLGA6B:
genes like me logo Genes that share phenotypes with GOLGA6B: view

Animal Model Products

CRISPR Products

miRNA for GOLGA6B Gene

miRTarBase miRNAs that target GOLGA6B

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for GOLGA6B Gene

Localization for GOLGA6B Gene

Subcellular locations from

Jensen Localization Image for GOLGA6B Gene COMPARTMENTS Subcellular localization image for GOLGA6B gene
Compartment Confidence
golgi apparatus 2

Gene Ontology (GO) - Cellular Components for GOLGA6B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005794 Golgi apparatus IEA --
genes like me logo Genes that share ontologies with GOLGA6B: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for GOLGA6B Gene

Pathways & Interactions for GOLGA6B Gene

SuperPathways for GOLGA6B Gene

No Data Available

Interacting Proteins for GOLGA6B Gene

STRING Interaction Network Preview (showing 3 interactants - click image to see details)
Selected Interacting proteins: ENSP00000408132 for GOLGA6B Gene via STRING

Gene Ontology (GO) - Biological Process for GOLGA6B Gene


No data available for Pathways by source and SIGNOR curated interactions for GOLGA6B Gene

Drugs & Compounds for GOLGA6B Gene

No Compound Related Data Available

Transcripts for GOLGA6B Gene

mRNA/cDNA for GOLGA6B Gene

(5) REFSEQ mRNAs :
(11) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for GOLGA6B

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for GOLGA6B Gene

No ASD Table

Relevant External Links for GOLGA6B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for GOLGA6B Gene

mRNA expression in normal human tissues for GOLGA6B Gene

mRNA differential expression in normal tissues according to GTEx for GOLGA6B Gene

This gene is overexpressed in Testis (x35.8).
genes like me logo Genes that share expression patterns with GOLGA6B: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for GOLGA6B Gene

Orthologs for GOLGA6B Gene

This gene was present in the common ancestor of chordates.

Orthologs for GOLGA6B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia -- 36
  • 34 (a)
(Canis familiaris)
Mammalia -- 36
  • 31 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 30 (a)
(Mus musculus)
Mammalia Golga2 36
  • 32 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 35 (a)
(Pan troglodytes)
Mammalia -- 36
  • 92 (a)
-- 36
  • 94 (a)
-- 36
  • 93 (a)
(Gallus gallus)
Aves -- 36
  • 27 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 26 (a)
(Danio rerio)
Actinopterygii golga2 36
  • 22 (a)
Species with no ortholog for GOLGA6B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GOLGA6B Gene

Gene Tree for GOLGA6B (if available)
Gene Tree for GOLGA6B (if available)

Paralogs for GOLGA6B Gene Pseudogenes for GOLGA6B Gene

genes like me logo Genes that share paralogs with GOLGA6B: view

Variants for GOLGA6B Gene

Sequence variations from dbSNP and Humsavar for GOLGA6B Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type MAF
rs354500 -- 72,652,987(+) AGAGG(G/T)AAGAG upstream-variant-2KB, intron-variant
rs744403 -- 72,663,638(+) gcacc(A/G)ctgca intron-variant
rs2037982 -- 72,666,796(+) TCATT(A/C)CAGAA utr-variant-3-prime
rs2114260 -- 72,667,868(+) ACTTA(C/T)GTTTC downstream-variant-500B
rs2439205 -- 72,665,126(+) TGATT(G/T)CTCTG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for GOLGA6B Gene

Variant ID Type Subtype PubMed ID
dgv755e1 CNV Complex 17122850
nsv428307 CNV Gain 18775914
nsv483057 CNV Loss 15286789
esv27409 CNV Gain 19812545
nsv821020 CNV Duplication 20802225
nsv9275 CNV Loss 18304495
esv1004072 CNV Gain 20482838

Variation tolerance for GOLGA6B Gene

Gene Damage Index Score: 5.89; 74.27% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for GOLGA6B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GOLGA6B Gene

Disorders for GOLGA6B Gene

Relevant External Links for GOLGA6B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with GOLGA6B: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GOLGA6B Gene

Publications for GOLGA6B Gene

  1. Analysis of the DNA sequence and duplication history of human chromosome 15. (PMID: 16572171) Zody M.C. … Nusbaum C. (Nature 2006) 67
  2. Neocentromeres in 15q24-26 map to duplicons which flanked an ancestral centromere in 15q25. (PMID: 12915487) Ventura M. … Rocchi M. (Genome Res. 2003) 67
  3. Human chromosome 15q11-q14 regions of rearrangements contain clusters of LCR15 duplicons. (PMID: 11896453) Pujana M.A. … Estivill X. (Eur. J. Hum. Genet. 2002) 67
  4. Additional complexity on human chromosome 15q: identification of a set of newly recognized duplicons (LCR15) on 15q11-q13, 15q24, and 15q26. (PMID: 11156619) Pujana M.A. … Estivill X. (Genome Res. 2001) 67
  5. A polymorphic genomic duplication on human chromosome 15 is a susceptibility factor for panic and phobic disorders. (PMID: 11509185) GratacA^s M. … Estivill X. (Cell 2001) 67

Products for GOLGA6B Gene

Sources for GOLGA6B Gene

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