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GOLGA5 Gene

protein-coding   GIFtS: 54
GCID: GC14P093260

Golgin A5

(Previous names: golgi autoantigen, golgin subfamily a, 5)
  See GOLGA5-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Golgin A51 2     Golgin Subfamily A Member 52
RFG52 3 5     golgin-842
Golgi Autoantigen, Golgin Subfamily A, 51 2     ret-II2
Golgi Integral Membrane Protein 51 2     Golgin-843
Cell Proliferation-Inducing Gene 31 Protein2 3     RETII3
RET-Fused Gene 5 Protein2 3     Protein Ret-II3
GOLIM52     PTC55

External Ids:    HGNC: 44281   Entrez Gene: 99502   Ensembl: ENSG000000664557   OMIM: 6069185   UniProtKB: Q8TBA63   

Export aliases for GOLGA5 gene to outside databases

Previous GC identifers: GC14P090767 GC14P087077 GC14P091250 GC14P092330 GC14P073443


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for GOLGA5 Gene:
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory
pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and
microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis.
This gene encodes one of the golgins, a family of proteins localized to the Golgi. This protein is a coiled-coil
membrane protein that has been postulated to play a role in vesicle tethering and docking. Translocations
involving this gene and the ret proto-oncogene have been found in tumor tissues; the chimeric sequences have been
designated RET-II and PTC5. A pseudogene of this gene is located on the short arm of chromosome 5. (provided by
RefSeq, Jul 2013)

GeneCards Summary for GOLGA5 Gene:
GOLGA5 (golgin A5) is a protein-coding gene. Diseases associated with GOLGA5 include papillary thyroid carcinoma, and chorea-acanthocytosis. GO annotations related to this gene include Rab GTPase binding and protein homodimerization activity.

UniProtKB/Swiss-Prot: GOGA5_HUMAN, Q8TBA6
Function: Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved
in intra-Golgi retrograde transport

Gene Wiki entry for GOLGA5 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000014.8  NC_018925.2  NT_026437.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the GOLGA5 gene promoter:
         SREBP-1c   Pax-6   SREBP-1b   IRF-2   POU2F1   SREBP-1a   POU2F1a   Chx10   MRF-2   ATF6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGOLGA5 promoter sequence
   Search Chromatin IP Primers for GOLGA5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat GOLGA5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q32.12   Ensembl cytogenetic band:  14q32.12   HGNC cytogenetic band: 14q32.12

GOLGA5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GOLGA5 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P093260:  view genomic region     (about GC identifiers)

Start:
93,260,576 bp from pter      End:
93,306,308 bp from pter
Size:
45,733 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: GOGA5_HUMAN, Q8TBA6 (See protein sequence)
Recommended Name: Golgin subfamily A member 5  
Size: 731 amino acids; 83024 Da
Subunit: Homodimer. Interacts with RAB1A that has been activated by GTP-binding, and possibly also with OCRL1.
Interacts with isoform CASP of CUX1
Sequence caution: Sequence=CAA33787.1; Type=Miscellaneous discrepancy; Note=Chimeric cDNA. A chimeric cDNA
originating from chromosomes 14 and 10;
Secondary accessions: C9JRU1 O95287 Q03962 Q2TS49 Q9UQQ7
Alternative splicing: 2 isoforms:  Q8TBA6-1   Q8TBA6-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for GOLGA5: NX_Q8TBA6

Explore proteomics data for GOLGA5 at MOPED

Post-translational modifications: 

  • Highly phosphorylated during mitosis. Phosphorylation is barely detectable during interphase1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See GOLGA5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_005104.3  
    ENSEMBL proteins: 
     ENSP00000163416   ENSP00000452601   ENSP00000348252  

    GOLGA5 Human Recombinant Protein Products:

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    antibodies-online peptides for GOLGA5

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR019177 Golgin_subfamily_A_member_5

    Graphical View of Domain Structure for InterPro Entry Q8TBA6

    ProtoNet protein and cluster: Q8TBA6


    Find genes that share domains with GOLGA5           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GOGA5_HUMAN, Q8TBA6
    Function: Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved
    in intra-Golgi retrograde transport

         Genatlas biochemistry entry for GOLGA5:
    Golgi autoantigen,golgin-84,subfamily A,member 5,ubiquitously expressed,abundantly in testis,forming the RET-II
    oncogene when fused by its coiled coil domain to the RET tyrosine kinase domain

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0017137Rab GTPase binding IDA12538640
    GO:0042803protein homodimerization activity IPI9915833
         
    Find genes that share ontologies with GOLGA5           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for GOLGA5

    miRNA
    Products:
        
    miRTarBase miRNAs that target GOLGA5:
    hsa-mir-16-5p (MIRT000846), hsa-mir-142-3p (MIRT021619), hsa-mir-1296-5p (MIRT036073), hsa-mir-15a-5p (MIRT000847)

    Block miRNA regulation of human, mouse, rat GOLGA5 using miScript Target Protectors
    2 qRT-PCR Assays for microRNAs that regulate GOLGA5:
    hsa-miR-670 hsa-miR-3920
    SwitchGear 3'UTR luciferase reporter plasmidGOLGA5 3' UTR sequence
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    GOGA5_HUMAN, Q8TBA6: Golgi apparatus membrane; Single-pass type IV membrane protein. Note=Found throughout the
    Golgi, both on cisternae and, at higher abundance, on the tubulo-vesicular structures of the cis-Golgi network
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    golgi apparatus5
    nucleus2
    cytosol1
    endoplasmic reticulum1
    mitochondrion1
    peroxisome1
    plasma membrane1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005794Golgi apparatus IDA--
    GO:0005801cis-Golgi network IDA12538640
    GO:0016021integral component of membrane IDA9915833
    GO:0031985Golgi cisterna IDA12538640

    Find genes that share ontologies with GOLGA5           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for GOLGA5
    Interactions:

        GeneGlobe Interaction Network for GOLGA5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    Selected Interacting proteins for GOLGA5 (Q8TBA63 ENSP000001634164) via UniProtKB, MINT, STRING, and/or I2D (see all 13)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CUX1P398803, ENSP000002925354I2D: score=1 I2D: score=1 STRING: ENSP00000292535
    RAB1AP628203, ENSP000003872864I2D: score=2 STRING: ENSP00000387286
    OCRLQ019683, ENSP000003601544I2D: score=2 STRING: ENSP00000360154
    NCAM2O153943, ENSP000003833924I2D: score=1 STRING: ENSP00000383392
    MEIS1O004703I2D: score=5 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007030Golgi organization IMP12538640
    GO:0048193Golgi vesicle transport IMP12538640

    Find genes that share ontologies with GOLGA5           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for GOLGA5 (GOGA5)

    1 HMDB Compound for GOLGA5    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--

    1 Novoseek inferred chemical compound relationship for GOLGA5 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tyrosine 15.7 1 9915833 (1)



    Find genes that share compounds with GOLGA5           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for GOLGA5 gene: 
    NM_005113.3  

    Unigene Cluster for GOLGA5:

    Golgin A5
    Hs.104320  [show with all ESTs]
    Unigene Representative Sequence: NM_005113
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000163416(uc001yaz.1) ENST00000555793 ENST00000554700 ENST00000355976(uc001yba.1)

    miRNA
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    2 qRT-PCR Assays for microRNAs that regulate GOLGA5:
    hsa-miR-670 hsa-miR-3920
    SwitchGear 3'UTR luciferase reporter plasmidGOLGA5 3' UTR sequence
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      QuantiTect SYBR Green Assays in human, mouse, rat GOLGA5
      QuantiFast Probe-based Assays in human, mouse, rat GOLGA5

    Additional mRNA sequence: 

    AF085199.1 AJ132949.1 AK293077.1 AK303789.1 AY644768.1 BC010134.2 BC023021.1 BX248744.1 

    11 DOTS entries:

    DT.418802  DT.120754669  DT.100026359  DT.101981921  DT.100798232  DT.100688610  DT.100798234  DT.100798233 
    DT.100800338  DT.40122962  DT.80102031 

    Selected AceView cDNA sequences (see all 212):

    AV728863 BI491601 AV681596 BU163136 AA292442 CD513087 CK725050 AI479708 
    BX116039 BQ669944 BQ014692 BI793315 CA389169 BG938455 AA236693 AA699342 
    AA402735 BM718473 BM817966 AI346630 AV650332 BU838407 BM458123 AA292491 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    GOLGA5 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTACAGGCTT
    GOLGA5 Expression
    About this image


    GOLGA5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 7) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Ovarian Mesenchymal Stroma Cells Ovary Interstitium
             Oviduct
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Pancreas (Endocrine System)
             Islets of Langerhans
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
    GOLGA5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    GOLGA5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.104320

    UniProtKB/Swiss-Prot: GOGA5_HUMAN, Q8TBA6
    Tissue specificity: Ubiquitous. Highly expressed in seminiferous tubules and Leydig cells in testis, and detected
    at much lower levels in the other tissues tested. Expression is very low or not detectable in spermatozoa

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for GOLGA5 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Golga51 , 5 golgi autoantigen, golgin subfamily a, 51, 5 83.04(n)1
    84.32(a)1
      12 (51.51 cM)5
    272771  NM_001199004.11  NP_001185933.11 
     1024691345 
    chicken
    (Gallus gallus)
    Aves GOLGA51 golgin A5 74.17(n)
    76.54(a)
      423419  XM_421329.4  XP_421329.2 
    lizard
    (Anolis carolinensis)
    Reptilia GOLGA56
    golgin A5
    71(a)
    1 ↔ 1
    1(11220692-11245407)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.157672 Transcribed sequence with weak similarity to protein more 76.66(n)    BX708080.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufd50h112 Danio rerio cDNA clone MGC66400 IMAGE5915039, complete more 73.4(n)    BC055639.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Golgin846
    Golgin84
    29(a)
    1 ↔ 1
    3R(20181792-20183645)
    worm
    (Caenorhabditis elegans)
    Secernentea T24B1.11 T24B1.1 44.68(n)
    30.05(a)
      172527  NM_059736.4  NP_492137.1 


    ENSEMBL Gene Tree for GOLGA5 (if available)
    TreeFam Gene Tree for GOLGA5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for GOLGA5 gene

    Find genes that share paralogs with GOLGA5           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for GOLGA5
    PGOHUM00000235195


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for GOLGA5 (see all 1200)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs354825901,2
    C--73479780(+) TTTTTT/-AGCTT 1 -- int12Minor allele frequency- -:0.00NA CSA 4
    rs354498071,2
    C--73483558(+) TCACC-/TTTTTT 1 -- int10--------
    rs49049951,2
    C,A,H--73486894(+) tttttC/Tttttg 1 -- int1 trp30--------
    rs1172742901,2
    C--74248712(+) ACCAAA/CCAAAC 1 -- us2k11Minor allele frequency- C:0.01EA 120
    rs1145870341,2
    C,F--74248795(+) TACTCC/TGAAGC 1 -- us2k11Minor allele frequency- T:0.03WA 118
    rs1451755141,2
    --74248796(+) ACTCCA/GAAGCC 1 -- us2k10--------
    rs10185391,2
    C,F,O,A,H--74248805(-) AAGGGT/CACAGG 1 -- us2k119Minor allele frequency- C:0.22MN NS EA NA WA CSA 2497
    rs1848340121,2
    --74248974(+) TCACAC/TTGTCC 1 -- us2k10--------
    rs10185381,2
    C,F,A,H--74248977(-) ttgggT/Acagtg 1 -- us2k115Minor allele frequency- A:0.23NS EA NA WA CSA 740
    rs1491424341,2
    C--74248982(+) TCCCAA/TGTTTG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for GOLGA5 (93260576 - 93306308 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for GOLGA5:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv819955CNV Loss19587683
    nsv522417CNV Gain19592680

    Human Gene Mutation Database (HGMD): GOLGA5
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing GOLGA5
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606918   
    OMIM disorders: 188550  
    UniProtKB/Swiss-Prot: GOGA5_HUMAN, Q8TBA6
  • Thyroid papillary carcinoma (TPC) [MIM:188550]: A common tumor of the thyroid that typically arises as an
    irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm
    characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered
    with a surface layer of neoplastic epithelial cells. Note=The gene represented in this entry is involved in
    disease pathogenesis. A chromosomal aberration involving GOLGA5 is found in thyroid papillary carcinomas.
    Translocation t(10;14)(q11;q32) with RET. The translocation generates the RET/GOLGA5 (PTC5) oncogene which was
    found in 2 cases of PACT in children exposed to radioactive fallout after Chernobyl

  • 3 diseases for GOLGA5:    
    About MalaCards
    papillary thyroid carcinoma    chorea-acanthocytosis    follicular thyroid carcinoma

    2 diseases from the University of Copenhagen DISEASES database for GOLGA5:
    Sigmoid colon cancer     Oculocerebrorenal syndrome

    Find genes that share disorders with GOLGA5           About GenesLikeMe

    1 Novoseek inferred disease relationship for GOLGA5 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tumors 0 1 9443391 (1)

    Genetic Association Database (GAD): GOLGA5

    Export disorders for GOLGA5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for GOLGA5 gene, integrated from 10 sources (see all 32):
    (articles sorted by number of sources associating them with GOLGA5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Detection of a novel type of Ret rearrangement (PTC5) in thyroid carcinomas after Chernobyl and analysis of the involved Ret-fused gene RFG5. (PubMed id 9443391)1, 2, 3, 9 Klugbauer S.... Rabes H.M. (Cancer Res. 1998)
    2. Activation of the ret-II oncogene without a sequence encoding a transmembrane domain and transforming activity of two ret-II oncogene products differing in carboxy-termini due to alternative splicing. (PubMed id 2734021)1, 2, 3 Ishizaka Y.... Nahao M. (Oncogene 1989)
    3. Identification and characterization of golgin-84, a novel Golgi integral membrane protein with a cytoplasmic coiled-coil domain. (PubMed id 9915833)1, 2, 9 Bascom R.A.... Nussbaum R.L. (J. Biol. Chem. 1999)
    4. The coiled-coil membrane protein golgin-84 is a novel rab effector required for Golgi ribbon formation. (PubMed id 12538640)1, 2, 9 Diao A.... Lowe M. (J. Cell Biol. 2003)
    5. Golgin tethers define subpopulations of COPI vesicles. (PubMed id 15718469)1, 2, 9 Malsam J.... Warren G. (Science 2005)
    6. The COG and COPI complexes interact to control the abundance of GEARs, a subset of Golgi integral membrane proteins. (PubMed id 15004235)1, 3, 9 Oka T....Krieger M. (Mol. Biol. Cell 2004)
    7. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    8. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (Nat. Biotechnol. 2005)
    9. Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. (PubMed id 15144186)1, 2 Brill L.M....Peters E.C. (Anal. Chem. 2004)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
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      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9950 HGNC: 4428 AceView: GOLGA5 Ensembl:ENSG00000066455 euGenes: HUgn9950
    ECgene: GOLGA5 H-InvDB: GOLGA5

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for GOLGA5 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for GOLGA5 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for GOLGA5 gene:
    Search GeneIP for patents involving GOLGA5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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