Aliases for GOLGA5 Gene
External Ids for GOLGA5 Gene
Previous GeneCards Identifiers for GOLGA5 Gene
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes one of the golgins, a family of proteins localized to the Golgi. This protein is a coiled-coil membrane protein that has been postulated to play a role in vesicle tethering and docking. Translocations involving this gene and the ret proto-oncogene have been found in tumor tissues; the chimeric sequences have been designated RET-II and PTC5. A pseudogene of this gene is located on the short arm of chromosome 5. [provided by RefSeq, Jul 2013]
GeneCards Summary for GOLGA5 Gene
GOLGA5 (Golgin A5) is a Protein Coding gene. Diseases associated with GOLGA5 include differentiated thyroid carcinoma and oculocerebrorenal syndrome. Among its related pathways are Vesicle-mediated transport and Golgi-to-ER retrograde transport. GO annotations related to this gene include protein homodimerization activity and Rab GTPase binding.
UniProtKB/Swiss-Prot for GOLGA5 Gene
Involved in maintaining Golgi structure. Stimulates the formation of Golgi stacks and ribbons. Involved in intra-Golgi retrograde transport.