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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GOLGA4 Gene

protein-coding   GIFtS: 53
GCID: GC03P037284

Golgin A4

(Previous names: golgi autoantigen, golgin subfamily a, 4)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Golgin A41 2     GOLG2
Golgi Autoantigen, Golgin Subfamily A, 41 2     MU-RMS-40.182
Protein 72.12 3     Golgin Subfamily A Member 42
Trans-Golgi P2302 3     golgin-2402
256 KDa Golgin2 3     golgin-2452
Golgin 2451     p2302
72.1 Protein2     Golgin-2453
GCP22     

External Ids:    HGNC: 44271   Entrez Gene: 28032   Ensembl: ENSG000001446747   OMIM: 6025095   UniProtKB: Q134393   

Export aliases for GOLGA4 gene to outside databases

Previous GC identifers: GC03P036667 GC03P036556 GC03P037097 GC03P037245 GC03P037259 GC03P037225


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GOLGA4 Gene:
The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory
pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and
microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis.
This gene encodes one of the golgins, a family of proteins localized to the Golgi. This protein has been
postulated to play a role in Rab6-regulated membrane-tethering events in the Golgi apparatus. Alternatively
spliced transcript variants encoding different isoforms have been identified in this gene. (provided by RefSeq,
Feb 2010)

GeneCards Summary for GOLGA4 Gene: 
GOLGA4 (golgin A4) is a protein-coding gene. Diseases associated with GOLGA4 include muir-torre syndrome, and lynch syndrome. GO annotations related to this gene include protein binding and GTPase binding.

UniProtKB/Swiss-Prot: GOGA4_HUMAN, Q13439
Function: May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi
network through its interaction with MACF1

Gene Wiki entry for GOLGA4 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NT_022517.18  NC_018914.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GOLGA4 gene promoter:
         HFH-3   AP-4   Egr-4   FOXI1   RORalpha1   Max   FOXO4   TGIF   LyF-1   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGOLGA4 promoter sequence
   Search SABiosciences Chromatin IP Primers for GOLGA4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GOLGA4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p22-p21.3   Ensembl cytogenetic band:  3p22.2   HGNC cytogenetic band: 3p22-p21.3

GOLGA4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GOLGA4 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P037284:  view genomic region     (about GC identifiers)

Start:
37,284,668 bp from pter      End:
37,408,370 bp from pter
Size:
123,703 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: GOGA4_HUMAN, Q13439 (See protein sequence)
Recommended Name: Golgin subfamily A member 4  
Size: 2230 amino acids; 261140 Da
Subunit: Homodimer. Interacts with GTP bound ARL1. Interacts with MACF1
Subcellular location: Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Golgi apparatus
Miscellaneous: Antibodies against GOLGA4 are present in sera from patients with Sjoegren syndrome. Sera from
patients with Sjoegren syndrome often contain antibodies that react with normal components of the Golgi complex
Sequence caution: Sequence=BAD92930.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Sequence=CAA58041.1; Type=Frameshift; Positions=2153;
2 PDB 3D structures from and Proteopedia for GOLGA4:
1R4A (3D)        1UPT (3D)    
Secondary accessions: F8W8Q7 Q13270 Q13654 Q14436 Q59EW8
Alternative splicing: 4 isoforms:  Q13439-1   Q13439-3   Q13439-4   Q13439-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for GOLGA4: NX_Q13439

Explore proteomics data for GOLGA4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q13439

  • GOLGA4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    GOLGA4 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001166184.1  NP_002069.2  

    ENSEMBL proteins: 
     ENSP00000354486   ENSP00000406894   ENSP00000349305   ENSP00000387633   ENSP00000403009  
     ENSP00000392907   ENSP00000405842  

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    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005737cytoplasm IDA15265687
    GO:0005794Golgi apparatus IDA15265687
    GO:0005802trans-Golgi network TAS1400343
    GO:0016020membrane ----

    GOLGA4 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR000237 GRIP

    Graphical View of Domain Structure for InterPro Entry Q13439

    ProtoNet protein and cluster: Q13439

    1 Blocks protein domain: IPB000237 GRIP domain

    UniProtKB/Swiss-Prot: GOGA4_HUMAN, Q13439
    Domain: Extended rod-like protein with coiled-coil domains
    Similarity: Contains 1 GRIP domain


    GOLGA4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GOGA4_HUMAN, Q13439
    Function: May play a role in delivery of transport vesicles containing GPI-linked proteins from the trans-Golgi
    network through its interaction with MACF1

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0005515protein binding IPI15265687
    GO:0051020GTPase binding IPI14580338
         
    GOLGA4 for ontologies           About GeneDecksing


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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for GOLGA4

    STRING Interaction Network Preview (showing 5 interactants - click image to see 15)

    5/23 Interacting proteins for GOLGA4 (Q134391, 3 ENSP000003544864) via UniProtKB, MINT, STRING, and/or I2D (see all 23)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ARL1P406163, ENSP000002616364I2D: score=3 STRING: ENSP00000261636
    MACF1Q9UPN33, ENSP000002898934I2D: score=2 STRING: ENSP00000289893
    ESR2Q927313, ENSP000003439254I2D: score=1 STRING: ENSP00000343925
    MCCP235083, ENSP000003862274I2D: score=1 STRING: ENSP00000386227
    NDNQ996083, ENSP000003326434I2D: score=1 STRING: ENSP00000332643
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000042protein targeting to Golgi IEA--
    GO:0016192vesicle-mediated transport TAS8626529
    GO:0043001Golgi to plasma membrane protein transport IDA15265687

    GOLGA4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for GOLGA4 (GOGA4)

    Search CenterWatch for drugs/clinical trials and news about GOLGA4 / GOGA4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GOLGA4 gene (2 alternative transcripts): 
    NM_001172713.1  NM_002078.4  

    Unigene Cluster for GOLGA4:

    Golgin A4
    Hs.344151  [show with all ESTs]
    Unigene Representative Sequence: NM_002078
    11 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000361924(uc003cgv.3 uc003cgw.3 uc010hgs.3 uc003cgx.3)
    ENST00000435830 ENST00000444882 ENST00000356847(uc003cgu.2 uc010hgr.2)
    ENST00000450863 ENST00000429018 ENST00000431105 ENST00000419177 ENST00000437131
    ENST00000497537 ENST00000498250
    miRNA
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    hsa-miR-30c hsa-miR-299-5p hsa-miR-92a hsa-miR-367 hsa-miR-25 hsa-miR-30d hsa-miR-32 hsa-miR-30a
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    Additional mRNA sequence: 

    AB209693.1 AF273047.1 AK290550.1 AK300192.1 AK307429.1 AY531221.2 BC023648.2 BC045543.1 
    BC050444.1 U31906.1 U41740.1 X76942.1 X82834.1 

    22 DOTS entries:

    DT.417428  DT.99952260  DT.100656601  DT.92044303  DT.91757945  DT.91961973  DT.120892783  DT.101975274 
    DT.120892753  DT.86843743  DT.91757969  DT.99969479  DT.40132143  DT.431597  DT.75173179  DT.86850213 
    DT.95163472  DT.95259305  DT.97792865  DT.97817198  DT.95163479  DT.95163483 

    24/333 AceView cDNA sequences (see all 333):

    BP343155 BU674986 BU193779 CA775035 BM693465 BX645186 CA445546 BI087265 
    BG573456 AV709759 U41740 BX506269 BC023648 BM982329 AA865345 CB132532 
    CA866672 NM_002078 BG623624 CB159039 CB215696 AU129809 BQ214559 CA943612 

    GeneLoc Exon Structure

    5/13 Alternative Splicing Database (ASD) splice patterns (SP) for GOLGA4 (see all 13)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b ^ 19 ^
    SP1:                                -     -           -     -     -           -     -                                                                           
    SP2:                                -     -           -     -     -           -     -                 -                                                         
    SP3:                                                                                                                                                            
    SP4:                                -     -           -     -     -     -     -     -                 -     -     -     -     -     -     -     -     -     -   
    SP5:                                -     -           -     -     -           -     -     -     -     -     -     -     -     -     -     -     -     -     -   

    ExUns: 20a · 20b ^ 21a · 21b ^ 22 ^ 23a · 23b ^ 24 ^ 25 ^ 26 ^ 27 ^ 28 ^ 29 ^ 30 ^ 31 ^ 32 ^ 33a · 33b
    SP1:                                      -                       -     -     -                 -               
    SP2:                                                                                                            
    SP3:                                                              -     -     -                                 
    SP4:  -     -     -     -     -     -     -     -     -     -     -     -     -     -     -     -               
    SP5:                                                                                                            


    ECgene alternative splicing isoforms for GOLGA4

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GOLGA4 expression in normal human tissues (normalized intensities)      GOLGA4 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAAAAAATCC
    GOLGA4 Expression
    About this image


    GOLGA4 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/47 selected tissues (see all 47) fully expand
     
     Brain (Nervous System)    fully expand to see all 6 entries
             Cerebral Cortex
             brain/hindbrain   
     
     Lung (Respiratory System)    fully expand to see all 5 entries
             Stem Bronchi
             lung ; pneumocytes   
     
     Uterus (Reproductive System)    fully expand to see all 5 entries
             uterus, post-menopause ; glandular cells   
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Epithelium (Uncategorized)    fully expand to see all 4 entries
             vagina ; squamous epithelial cells   

    See GOLGA4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GOLGA4

    SOURCE GeneReport for Unigene cluster: Hs.344151
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for GOLGA4 gene from 8/17 species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Golga41 , 5 golgi autoantigen, golgin subfamily a, 41, 5 76.18(n)1
    71.91(a)1
      9 (70.23 cM)5
    542141  NM_018748.31  NP_061218.21 
     1185063185 
    chicken
    (Gallus gallus)
    Aves GOLGA41 golgin A4 67.38(n)
    61.65(a)
      420758  XM_418856.3  XP_418856.3 
    lizard
    (Anolis carolinensis)
    Reptilia GOLGA46
    Uncharacterized protein
    56(a)
    1 ↔ 1
    6(43851261-43982199)
    African clawed frog
    (Xenopus laevis)
    Amphibia BC059323.12   -- 73.6(n)    BC059323.1 
    zebrafish
    (Danio rerio)
    Actinopterygii golga41 golgin A4 53.4(n)
    44.28(a)
      559226  XM_001921263.3  XP_001921298.3 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG34931 , 3 CG34931 20(a)3
    40.33(n)1
    25.09(a)1
      59D93
    377021  NM_137943.21  NP_611787.21 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes USO16
    Essential protein involved in the vesicle-mediated...
    12(a)
    1 → many
    IV(345665-351037)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons CIP11 COP1-interactive protein 1 42.01(n)
    26.17(a)
      834184  NM_123544.3  NP_198994.2 


    ENSEMBL Gene Tree for GOLGA4 (if available)
    TreeFam Gene Tree for GOLGA4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GOLGA4 gene

    GOLGA4 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for GOLGA4
    PGOHUM00000240271


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2599 SNPs in GOLGA4 are shown (see all 2599)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs117101311,2
    C,F,H--37282685(+) TATATG/ATATAC 2 -- us2k15Minor allele frequency- A:0.26NA EA 248
    rs789345341,2
    F--37282687(+) TATGTA/GTACAT 2 -- us2k11Minor allele frequency- G:0.01WA 118
    rs1814445401,2
    --37283059(+) TGTCCA/GCCTCG 2 -- us2k10--------
    rs1387794911,2
    C--37283063(+) CGCCTC/TGGCCT 2 -- us2k10--------
    rs801885801,2
    C,F--37283107(+) GTACCC/TGGCTG 2 -- us2k11Minor allele frequency- T:0.50WA 2
    rs1473894451,2
    C--37283563(+) TCTGAA/CAGGAG 2 -- us2k10--------
    rs119197511,2
    C,F,H--37283666(+) agcccG/Agttcc 2 -- us2k14Minor allele frequency- A:0.08NA CSA WA 244
    rs344392841,2
    C,F--37283757(+) TAAGAG/AGACTT 2 -- us2k13Minor allele frequency- A:0.33NA 6
    rs1857376281,2
    --37284065(+) GATGAC/TTGCAG 2 -- us2k10--------
    rs1416456401,2
    --37284115(+) TTCCAA/CTAGGC 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for GOLGA4 (37284668 - 37408370 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for GOLGA4:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv269812CNV Insertion20981092
    nsv834665CNV Loss17160897
    nsv834664CNV Loss17160897
    nsv876704CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 602509    OMIM disorders: --

    8 diseases for GOLGA4:    About MalaCards
    muir-torre syndrome    lynch syndrome    cutaneous t cell lymphoma    sjogren's syndrome
    chronic myeloid leukemia    myeloid leukemia    schizophrenia    leukemia


    GOLGA4 for disorders           About GeneDecksing


    Export disorders for GOLGA4 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GOLGA4 gene, integrated from 9 sources (see all 55):
    (articles sorted by number of sources associating them with GOLGA4)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular characterization of trans-Golgi p230: a human peripheral membrane protein encoded by a gene on chromosome 6p12-22 contains extensive coiled-coil alpha-helical domains and a granin motif. (PubMed id 8626529)1, 2, 3, 9 Erlich R.... Toh B.-H. (1996)
    2. Interaction between p230 and MACF1 is associated with transport of a glycosyl phosphatidyl inositol-anchored protein from the Golgi to the cell periphery. (PubMed id 15265687)1, 2, 9 Kakinuma T....Toh B.H. (2004)
    3. Structural basis for Arl1-dependent targeting of homodimeric GRIP domains to the Golgi apparatus. (PubMed id 14580338)1, 2, 9 Panic B....Munro S. (2003)
    4. Molecular characterization of golgin-245, a novel Golgi complex protein containing a granin signature. (PubMed id 8537393)1, 2, 9 Fritzler M.J.... Chan E.K.L. (1995)
    5. Structural basis for recruitment of GRIP domain golgin-245 by small GTPase Arl1. (PubMed id 14718928)1, 2, 9 Wu M.... Song H. (2004)
    6. ADP-ribosylation factors (ARFs) and ARF-like 1 (ARL1) have both specific and shared effectors: characterizing ARL1-binding proteins. (PubMed id 11303027)1, 2, 9 Van Valkenburgh H.... Kahn R.A. (2001)
    7. p230 is associated with vesicles budding from the trans-Golgi network. (PubMed id 9013329)1, 9 Gleeson P.A....Matheson F. (1996)
    8. Regulation of HLA class I surface expression requires CD99 and p230/golgin-245 interaction. (PubMed id 18849489)1, 9 BrAcmond A....Bernard G. (2009)
    9. tGolgin-1 (p230, golgin-245) modulates Shiga-toxin transport to the Golgi and Golgi motility towards the microtubule-organizing centre. (PubMed id 15870108)1, 9 Yoshino A....Marks M.S. (2005)
    10. Interaction of Arl1-GTP with GRIP domains recruits autoantigens Golgin-97 and Golgin-245/p230 onto the Golgi. (PubMed id 12972563)1, 9 Lu L. and Hong W. (2003)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 2803 HGNC: 4427 AceView: GOLGA4 Ensembl:ENSG00000144674 euGenes: HUgn2803
    ECgene: GOLGA4 H-InvDB: GOLGA4

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GOLGA4 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for GOLGA4 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for GOLGA4 gene:
    Search GeneIP for patents involving GOLGA4

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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