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GNRH2 Gene

protein-coding   GIFtS: 52
GCID: GC20P003048

Gonadotropin-Releasing Hormone 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Gonadotropin-Releasing Hormone 21 2     Luliberin II2
Progonadoliberin II2 3     Luteinizing Hormone-Releasing Hormone II2
GnRH-II2     progonadoliberin-22
LH-RHII2     

External Ids:    HGNC: 44201   Entrez Gene: 27972   Ensembl: ENSG000001257877   OMIM: 6023525   UniProtKB: O435553   

Export aliases for GNRH2 gene to outside databases

Previous GC identifers: GC20P003012 GC20P002972 GC20P003019 GC20P003033 GC20P003038 GC20P003043


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for GNRH2 Gene:
The protein encoded by this gene is a preproprotein that is cleaved to form a secreted 10 aa peptide hormone. The
secreted decapeptide regulates reproduction in females by stimulating the secretion of both luteinizing- and
follicle-stimulating hormones. Three transcript variants that encode unique proproteins but the same peptide
hormone have been found for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for GNRH2 Gene:
GNRH2 (gonadotropin-releasing hormone 2) is a protein-coding gene. Diseases associated with GNRH2 include ovarian epithelial cancer, and medulloblastoma. GO annotations related to this gene include hormone activity.

UniProtKB/Swiss-Prot: GON2_HUMAN, O43555
Function: Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and
follicle-stimulating hormones

Gene Wiki entry for GNRH2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000020.11  NT_011387.9  NC_018931.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the GNRH2 gene promoter:
         CREB   AP-1   ATF-2   deltaCREB   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGNRH2 promoter sequence
   Search Chromatin IP Primers for GNRH2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat GNRH2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 20p13   Ensembl cytogenetic band:  20p13   HGNC cytogenetic band: 20p13

GNRH2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GNRH2 gene location

GeneLoc information about chromosome 20         GeneLoc Exon Structure

GeneLoc location for GC20P003048:  view genomic region     (about GC identifiers)

Start:
3,024,268 bp from pter      End:
3,026,393 bp from pter
Size:
2,126 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: GON2_HUMAN, O43555 (See protein sequence)
Recommended Name: Progonadoliberin-2 precursor  
Size: 120 amino acids; 12918 Da
Secondary accessions: Q14C68 Q14C69 Q9BYN9 Q9BYP0
Alternative splicing: 3 isoforms:  O43555-1   O43555-2   O43555-3   

Explore the universe of human proteins at neXtProt for GNRH2: NX_O43555

Explore proteomics data for GNRH2 at MOPED


See GNRH2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (3 alternative transcripts): 
NP_001492.1  NP_847901.1  NP_847902.1  

ENSEMBL proteins: 
 ENSP00000245983   ENSP00000352003   ENSP00000369705   ENSP00000369704   ENSP00000353077  
Reactome Protein details: O43555

GNRH2 Human Recombinant Protein Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
ENDOLIG: Endogenous ligands

2 InterPro protein domains:
 IPR019792 Gonadoliberin_I
 IPR002012 GnRH

Graphical View of Domain Structure for InterPro Entry O43555

ProtoNet protein and cluster: O43555

UniProtKB/Swiss-Prot: GON2_HUMAN, O43555
Similarity: Belongs to the GnRH family


GNRH2 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: GON2_HUMAN, O43555
Function: Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and
follicle-stimulating hormones

     Genatlas biochemistry entry for GNRH2:
gonadotropin releasing hormone 2,mesencephalic form,expressed in midbrain,kidney,bone marrow prostate,including a
GNRH-associated peptide

     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005179hormone activity IEA--
     
GNRH2 for ontologies           About GeneDecksing


Phenotypes:
     4 GenomeRNAi human phenotypes for GNRH2:
 Decreased Salmonella enterica   Decreased influenza A H1N1 (A/  Decreased influenza A/WSN/33 r  Increased cell number in G2M,  

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for GNRH2
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GenScript: all cDNA clones in your preferred vector (see all 3): GNRH2 (NM_178331)
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GNRH2

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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
GON2_HUMAN, O43555: Secreted
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
extracellular5
mitochondrion1
nucleus1

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005576extracellular region TAS--

GNRH2 for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for GNRH2 About   (see all 19)  
See pathways by source

SuperPathSelected contained pathways About (see all per SuperPath)
1Apoptotic Pathways in Synovial Fibroblasts
Mitochondrial Apoptosis0.85
Rac1 Pathway0.65
Cellular Apoptosis Pathway0.85
Glioma Invasiveness0.64
Apoptotic Pathways in Synovial Fibroblasts0.84
Actin-Based Motility by Rho Family GTPases0.62
p53 Mediated Apoptosis0.84
ERK5 Signaling0.61
2GPCR Pathway
Ras Pathway0.73
Breast Cancer Regulation by Stathmin10.58
Paxillin Interactions0.73
NFAT in Immune Response0.58
GPCR Pathway0.62
Estrogen Pathway0.55
Pancreatic Adenocarcinoma0.59
3ERK Signaling
Rho Family GTPases0.61
Molecular Mechanisms of Cancer0.51
ERK Signaling0.61
ILK Signaling0.49
MAPK Signaling0.58
4Nanog in Mammalian ESC Pluripotency
Nanog in Mammalian ESC Pluripotency0.61
14-3-3 Induced Intracellular Signaling0.59
GSK3 Signaling0.61
eNOS Signaling0.48
5TGF-Beta Pathway
TGF-Beta Pathway0.60
JAK-STAT Pathway0.57
MAPK Family Pathway0.60
JNK Pathway0.51

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways

Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for GNRH2 (see all 56)
    Nuclear Receptor Activation by Vitamin-A
Paxillin Interactions
Telomerase Components in Cell Signaling
Mitochondrial Apoptosis
Molecular Mechanisms of Cancer


2 Reactome Pathways for GNRH2
    Hormone ligand-binding receptors
G alpha (q) signalling events


1 Kegg Pathway  (Kegg details for GNRH2):
    GnRH signaling pathway


GNRH2 for pathways           About GeneDecksing

    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for GNRH2
Interactions:

    GeneGlobe Interaction Network for GNRH2

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

Selected Interacting proteins for GNRH2 (ENSP000002459834) via UniProtKB, MINT, STRING, and/or I2D (see all 123)
InteractantInteraction Details
GeneCardExternal ID(s)
CCKENSP000003356574STRING: ENSP00000335657
CCKARENSP000002955894STRING: ENSP00000295589
CCKBRENSP000003355444STRING: ENSP00000335544
F2RL1ENSP000002966774STRING: ENSP00000296677
GCGENSP000003876624STRING: ENSP00000387662
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Gene Ontology (GO): 2 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0007165signal transduction TAS9419371
GO:0007275multicellular organismal development IEA--

GNRH2 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for GNRH2 (GON2)

6 Novoseek inferred chemical compound relationships for GNRH2 gene    About this table
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
gnrh 86.5 69 12466358 (3), 17906381 (2), 11159856 (2), 9762908 (2) (see all 38)
cetrorelix 74.1 2 12466358 (1), 12915673 (1)
ribonucleic acid 44.5 1 12574197 (1)
mifepristone 41.2 3 12574197 (2), 15562029 (1)
progesterone 31.6 14 16860054 (3), 15562029 (2), 11145581 (2), 16728408 (1) (see all 5)
tyrosine 0 2 17308117 (1), 14680798 (1)



GNRH2 for compounds           About GeneDecksing



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for GNRH2 gene (3 alternative transcripts): 
NM_001501.1  NM_178331.1  NM_178332.1  

Unigene Cluster for GNRH2:

Gonadotropin-releasing hormone 2
Hs.129715  [show with all ESTs]
Unigene Representative Sequence: EL736362
5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000245983(uc002whr.1 uc010gau.1) ENST00000359100(uc002whp.1)
ENST00000380347 ENST00000380346 ENST00000359987(uc002whq.1)
miRNA
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Predesigned siRNA for gene silencing in human, mouse, rat GNRH2
Clone
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GenScript: all cDNA clones in your preferred vector (see all 3): GNRH2 (NM_178331)
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Additional mRNA sequence: 

AF036330.1 AF190640.1 BC069362.1 BC115399.1 BC115400.1 

2 DOTS entries:

DT.40282805  DT.92067931 

10 AceView cDNA sequences:

BF061974 AF190640 NM_001501 BC069362 NM_178332 BF062277 AF036330 NM_178331 
AL732156 AA864512 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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GNRH2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
GNRH2 Expression
About this image

GNRH2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

GNRH2 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.129715

UniProtKB/Swiss-Prot: GON2_HUMAN, O43555
Tissue specificity: Midbrain; expressed at significantly higher levels outside the brain (up to 30-fold),
particularly in the kidney, bone marrow and prostate

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In Situ
Assay Products:
 

 
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(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of mammals.

Orthologs for GNRH2 gene from Selected species (see all 2)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
cow
(Bos taurus)
Mammalia GNRH21 gonadotropin-releasing hormone 2 74.19(n)
60.22(a)
  100848664  XM_003586799.2  XP_003586847.2 


ENSEMBL Gene Tree for GNRH2 (if available)
TreeFam Gene Tree for GNRH2 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for GNRH2 (see all 34)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 20 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs777297291,2
C,F--3022464(+) CCCCCG/ACATCC 3 -- us2k12Minor allele frequency- A:0.09WA EA 238
rs1509823161,2
--3022578(+) ATCCAC/TGGCAG 3 -- us2k10--------
rs61389901,2
C,F,A,H--3022618(+) TTATGC/TTGCAC 3 -- us2k124Minor allele frequency- T:0.22NS EA NA CSA WA 2764
rs60842391,2
F,H--3022766(+) CCCACC/TTGAGT 3 -- us2k14Minor allele frequency- T:0.00NS EA 420
rs1808987711,2
--3022844(+) TTCTAA/TGTTCT 3 -- us2k10--------
rs1497407971,2
--3022911(+) TAAAAA/GCTAAG 3 -- us2k10--------
rs345870341,2
C--3022927(+) GCCGG-/A/GAAAAA 3 -- us2k10--------
rs37612431,2
C,F,A,H--3023022(+) AGGCAA/CCCATC 3 -- us2k121Minor allele frequency- C:0.36EA NS NA WA CSA 2862
rs1858997911,2
--3023152(+) TTTCCC/GTAAAA 3 -- us2k10--------
rs1467641341,2
--3023179(+) AGTCCA/GCATAT 3 -- us2k10--------

HapMap Linkage Disequilibrium report for GNRH2 (3024268 - 3026393 bp)

Structural Variations
     Database of Genomic Variants (DGV) 4 variations for GNRH2:    About this table    
Variant IDTypeSubtypePubMed ID
nsv833896CNV Loss17160897
nsv833897CNV Loss17160897
nsv912603CNV Gain21882294
nsv482064CNV Gain20164927

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing GNRH2
DNA2.0 Custom Variant and Variant Library Synthesis for GNRH2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 602352    OMIM disorders: --

12 diseases for GNRH2:    
About MalaCards
ovarian epithelial cancer    medulloblastoma    ovarian cancer    leiomyoma
endometrial carcinoma    infertility    prostate cancer    prostatitis
breast cancer    neuronitis    adenocarcinoma    pancreatitis


GNRH2 for disorders           About GeneDecksing

4 Novoseek inferred disease relationships for GNRH2 gene    About this table

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
medulloblastoma 54.4 3 11459794 (1), 15562029 (1), 11931351 (1)
ovarian cancer 49.1 15 17308117 (5), 17906381 (1), 16189183 (1), 11600588 (1) (see all 9)
tumors 0 8 15380810 (2), 17906381 (1), 11600588 (1), 12770744 (1) (see all 6)
cancer 0 3 17202595 (1), 18222967 (1), 17308117 (1)

Genetic Association Database (GAD): GNRH2
Human Genome Epidemiology (HuGE) Navigator: GNRH2 (5 documents)

Export disorders for GNRH2 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for GNRH2 gene, integrated from 10 sources (see all 91):
(articles sorted by number of sources associating them with GNRH2)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Second gene for gonadotropin-releasing hormone in humans. (PubMed id 9419371)1, 2, 3, 9 White R.B.... Fernald R.D. (Proc. Natl. Acad. Sci. U.S.A. 1998)
  2. The neuropeptides GnRH-II and GnRH-I are produced by human T cells and trigger laminin receptor gene expression, adhesion, chemotaxis and homing to specific organs. (PubMed id 12447356)1, 3, 9 Chen A....Levite M. (Nat. Med. 2002)
  3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
  4. High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men. (PubMed id 19453261)1, 4 Yerges L.M....Zmuda J.M. (J. Bone Miner. Res. 2009)
  5. Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. (PubMed id 19086053)1, 4 GratacA^s M....Carracedo A. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2009)
  6. Polymorphism in the IL18 gene and epithelial ovarian cancer in non-Hispanic white women. (PubMed id 19064572)1, 4 Palmieri R.T.... . (amp 2008)
  7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  8. The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (Nature 2001)
  9. Transcriptional regulation of the human GnRH II gene is mediated by a putative cAMP response element. (PubMed id 11459794)1, 9 Chen A....Koch Y. (Endocrinology 2001)
  10. Cellular localization of gonadotropin-releasing hormone (GnRH) I and GnRH II in first-trimester human placenta and decidua. (PubMed id 15001648)1, 9 Chou C.S....Leung P.C. (J. Clin. Endocrinol. Metab. 2004)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 2797 HGNC: 4420 AceView: GNRH2 Ensembl:ENSG00000125787 euGenes: HUgn2797
ECgene: GNRH2 Kegg: 2797 H-InvDB: GNRH2

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for GNRH2 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for GNRH2 gene:
Search GeneIP for patents involving GNRH2

Licensable Technologies for GNRH2 gene:
Weizmann Institute:"Modulation of Neurotransmitter Receptors on T-cell Membranes: a Novel Approach for Treatment of Autoimmune, Infectious and Malignant"
GeneCards and IP:
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