Aliases for GNRH1 Gene
External Ids for GNRH1 Gene
Previous HGNC Symbols for GNRH1 Gene
Previous GeneCards Identifiers for GNRH1 Gene
This gene encodes a preproprotein that is proteolytically processed to generate a peptide that is a member of the gonadotropin-releasing hormone (GnRH) family of peptides. Alternative splicing results in multiple transcript variants, at least one of which is secreted and then cleaved to generate gonadoliberin-1 and GnRH-associated peptide 1. Gonadoliberin-1 stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutations in this gene are associated with hypogonadotropic hypogonadism. [provided by RefSeq, Nov 2015]
GeneCards Summary for GNRH1 Gene
GNRH1 (Gonadotropin Releasing Hormone 1) is a Protein Coding gene. Diseases associated with GNRH1 include Hypogonadotropic Hypogonadism 12 With Or Without Anosmia and Normosmic Congenital Hypogonadotropic Hypogonadism. Among its related pathways are Peptide ligand-binding receptors and p70S6K Signaling. GO annotations related to this gene include hormone activity and gonadotropin hormone-releasing hormone activity.
UniProtKB/Swiss-Prot for GNRH1 Gene
Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones.