Aliases for GNRH1 Gene
External Ids for GNRH1 Gene
Previous Symbols for GNRH1 Gene
The protein encoded by this gene is secreted and then cleaved to form the 10 aa luteinizing hormone-releasing hormone (LHRH, also known as gonadoliberin-1), and prolactin release-inhibiting factor (also known as GnRH-associated peptide 1). LHRH stimulates the release of luteinizing and follicle stimulating hormones, which are important for reproduction. Mutation in this gene are associated with hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2012]
GeneCards Summary for GNRH1 Gene
GNRH1 (Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone)) is a Protein Coding gene. Diseases associated with GNRH1 include hypogonadotropic hypogonadism 12 with or without anosmia and secondary central precocious puberty. Among its related pathways are Signaling by GPCR and NF-KappaB Family Pathway. GO annotations related to this gene include hormone activity and gonadotropin hormone-releasing hormone activity.
UniProtKB/Swiss-Prot for GNRH1 Gene
Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones