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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GNPDA2 Gene

protein-coding   GIFtS: 60
GCID: GC04M044704

Glucosamine-6-Phosphate Deaminase 2

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Glucosamine-6-Phosphate Deaminase 21 2 3     Glucosamine-6-Phosphate Isomerase1
GNP22 3 5     SB522
GlcN6P Deaminase 22 3     Glucosamine-6-Phosphate Isomerase 22
Glucosamine-6-Phosphate Isomerase SB522 3     GNPDA 23
EC 3.5.99.63 8     

External Ids:    HGNC: 215261   Entrez Gene: 1327892   Ensembl: ENSG000001632817   OMIM: 6132225   UniProtKB: Q8TDQ73   

Export aliases for GNPDA2 gene to outside databases

Previous GC identifers: GC04M044619 GC04M044545 GC04M044398 GC04M044025


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GNPDA2 Gene:
The protein encoded by this gene is an allosteric enzyme that catalyzes the reversible reaction converting
D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. Variations of this gene have been reported to
be associated with influencing body mass index and susceptibility to obesity. A pseudogene of this gene is
located on chromosome 9. Alternative splicing results in multiple transcript variants that encode different
protein isoforms. (provided by RefSeq, Aug 2012)

GeneCards Summary for GNPDA2 Gene: 
GNPDA2 (glucosamine-6-phosphate deaminase 2) is a protein-coding gene. Diseases associated with GNPDA2 include obesity, and anorexia nervosa, and among its related super-pathways are N-acetylglucosamine degradation II and Metabolism. GO annotations related to this gene include hydrolase activity and glucosamine-6-phosphate deaminase activity. An important paralog of this gene is GNPDA1.

Gene Wiki entry for GNPDA2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NT_006238.11  NC_018915.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GNPDA2 gene promoter:
         c-Fos   GATA-3   AP-1   POU3F1   Pax-6   Lmo2   LCR-F1   Evi-1   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGNPDA2 promoter sequence
   Search SABiosciences Chromatin IP Primers for GNPDA2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GNPDA2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p12   Ensembl cytogenetic band:  4p12   HGNC cytogenetic band: 4p13

GNPDA2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GNPDA2 gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M044704:  view genomic region     (about GC identifiers)

Start:
44,703,885 bp from pter      End:
44,728,612 bp from pter
Size:
24,728 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: GNPI2_HUMAN, Q8TDQ7 (See protein sequence)
Recommended Name: Glucosamine-6-phosphate isomerase 2  
Size: 276 amino acids; 31085 Da
Subunit: Homohexamer (By similarity)
Subcellular location: Cytoplasm (By similarity)
Sequence caution: Sequence=BAD93141.1; Type=Erroneous initiation;
Secondary accessions: B4DJF3 Q2VYF1 Q59EA7 Q8NCZ8 Q96BJ4 Q96NC6
Alternative splicing: 5 isoforms:  Q8TDQ7-1   Q8TDQ7-2   Q8TDQ7-3   Q8TDQ7-4   Q8TDQ7-5   

Explore the universe of human proteins at neXtProt for GNPDA2: NX_Q8TDQ7

Explore proteomics data for GNPDA2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8TDQ7

  • 4/14 DME Specific Peptides for GNPDA2 (Q8TDQ7) (see all 14)
     FNEPGSS  HILDGNA  TGSTPLG  NFFKHIDI 

    GNPDA2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    GNPDA2 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001257809.1  NP_001257810.1  NP_612208.1  

    ENSEMBL proteins: 
     ENSP00000425868   ENSP00000295448   ENSP00000427423   ENSP00000424061  

    Human Recombinant Protein Products for GNPDA2: 
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    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--

    GNPDA2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR006148 Glc/Gal-6P_isomerase
     IPR004547 Glucosamine6P_isomerase
     IPR018321 Glucosamine6P_isomerase_CS

    Graphical View of Domain Structure for InterPro Entry Q8TDQ7

    ProtoNet protein and cluster: Q8TDQ7

    1 Blocks protein domain: IPB004547 Glucosamine-6-phosphate isomerase

    UniProtKB/Swiss-Prot: GNPI2_HUMAN, Q8TDQ7
    Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family


    GNPDA2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GNPI2_HUMAN, Q8TDQ7
    Catalytic activity: D-glucosamine 6-phosphate + H(2)O = D-fructose 6-phosphate + NH(3)

         Enzyme Number (IUBMB): EC 3.5.99.61 2

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004342glucosamine-6-phosphate deaminase activity IEA--
    GO:0016787hydrolase activity IEA--
         
    GNPDA2 for ontologies           About GeneDecksing


    Animal Models:
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    SwitchGear 3'UTR luciferase reporter plasmidGNPDA2 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for GNPDA2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1N-acetylglucosamine degradation I
    N-acetylglucosamine degradation I0.75
    N-acetylglucosamine degradation II0.75
    2Metabolism
    Metabolic pathways0.40
    3UDP-N-acetyl-D-glucosamine biosynthesis II
    UDP-N-acetyl-D-galactosamine biosynthesis II0.30
    4Amino sugar and nucleotide sugar metabolism
    Amino sugar and nucleotide sugar metabolism

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3 BioSystems Pathways for GNPDA2
        UDP-N-acetyl-D-galactosamine biosynthesis II
    N-acetylglucosamine degradation I
    N-acetylglucosamine degradation II



    2         Kegg Pathways  (Kegg details for GNPDA2):
        Amino sugar and nucleotide sugar metabolism
    Metabolic pathways


    GNPDA2 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GNPDA2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

    5/11 Interacting proteins for GNPDA2 (Q8TDQ73 ENSP000002954484) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ILF2Q129053, ENSP000003550114I2D: score=1 STRING: ENSP00000355011
    GNPNAT1ENSP000002164104STRING: ENSP00000216410
    GPIENSP000003488774STRING: ENSP00000348877
    MPIENSP000003183184STRING: ENSP00000318318
    HK2ENSP000002905734STRING: ENSP00000290573
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005975carbohydrate metabolic process IEA--
    GO:0006044N-acetylglucosamine metabolic process IEA--

    GNPDA2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GNPDA2 (GNPI2)

    4 HMDB Compounds for GNPDA2    About this table
    CompoundSynonyms CAS #PubMed Ids
    AmmoniaNH3 (see all 31)7664-41-7--
    Glucosamine 6-phosphate2-Amino-2-deoxy-D-glucose 6-phosphate (see all 14)3616-42-0--
    N-Acetyl-D-Glucosamine 6-PhosphateN-Acetyl-D-Glucosamine 6-Phosphate (see all 7)102029-88-9--
    WaterDihydrogen oxide (see all 2)7732-18-5--

    Search CenterWatch for drugs/clinical trials and news about GNPDA2 / GNPI2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GNPDA2 gene (3 alternative transcripts): 
    NM_001270880.1  NM_001270881.1  NM_138335.2  

    Unigene Clusters for GNPDA2:

    Glucosamine-6-phosphate deaminase 2
    Hs.21398  [show with all ESTs], Hs.597934  [show with all ESTs]
    Unigene Representative Sequences: NM_138335, AB209904
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000507917 ENST00000295448(uc003gwy.3 uc010iga.3 uc011bzb.2)
    ENST00000507534 ENST00000509756(uc003gwz.1) ENST00000511187
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

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    hsa-miR-142-5p hsa-miR-302d hsa-miR-520e hsa-miR-106a hsa-miR-25 hsa-miR-372 hsa-miR-124 hsa-miR-93
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GNPDA2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GNPDA2

    Additional mRNA sequence: AB209904.1 

    9 DOTS entries:

    DT.443522  DT.108318  DT.97776550  DT.95144357  DT.95086266  DT.97841113  DT.91643445  DT.121219738 
    DT.121219770 

    1 AceView cDNA sequence:

    AK129655 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for GNPDA2    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b
    SP1:                                                              -     -               
    SP2:                                                                                    
    SP3:                          -     -     -     -                 -                     
    SP4:                          -     -     -     -                 -     -               
    SP5:                          -                                                         


    ECgene alternative splicing isoforms for GNPDA2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GNPDA2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CATTAGGAGA
    GNPDA2 Expression
    About this image


    See GNPDA2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GNPDA2

    SOURCE GeneReport for Unigene clusters: Hs.21398 Hs.597934
        SABiosciences Custom PCR Arrays for GNPDA2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GNPDA2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for GNPDA2 gene from 7/16 species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gnpda21 , 5 glucosamine-6-phosphate deaminase 21, 5 89.61(n)1
    97.1(a)1
      5 (37.13 cM)5
    679801  NM_001038015.11  NP_001033104.11 
     695731085 
    chicken
    (Gallus gallus)
    Aves GNPDA21 glucosamine-6-phosphate deaminase 2 85.04(n)
    94.89(a)
      422772  XM_420726.3  XP_420726.2 
    lizard
    (Anolis carolinensis)
    Reptilia GNPDA26
    --
    Uncharacterized protein
    94(a)
    83(a)
    1 ↔ 1
    possible ortholog
    5(102297520-102310685)
    2(127050126-127065470)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC685932 hypothetical protein MGC68593 80.64(n)    BC060461.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5562911 glucosamine-6-phosphate isomerase 2-like 74.45(n)
    87.59(a)
      556291  XM_679055.3  XP_684147.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta Oscillin1 CG6957-PA 66.8(n)
    77.22(a)
      33783  NM_135094.2  NP_608938.1 
    worm
    (Caenorhabditis elegans)
    Secernentea T03F6.36
    Probable glucosamine-6-phosphate isomerase
    66(a)
    1 → many
    III(13389382-13390867)


    ENSEMBL Gene Tree for GNPDA2 (if available)
    TreeFam Gene Tree for GNPDA2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GNPDA2 gene
    GNPDA12  
    1 SIMAP similar gene for GNPDA2 using alignment to 1 protein entry:     GNPI2_HUMAN:
    GNPDA1

    GNPDA2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for GNPDA2
    PGOHUM00000250527


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/535 SNPs in GNPDA2 are shown (see all 535)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1391930351,2
    C--44703445(+) TCAGT-/GGTTGG 5 -- ds50010--------
    rs1811476001,2
    --44703540(+) GTTTTC/GGCTCC 5 -- ds50010--------
    rs721972511,2
    C--44703582(+) CTCAACTAAG   
       CCC
    /-
    CTAAC
    5 -- ds50011Minor allele frequency- -:0.50CSA 2
    rs1863816371,2
    --44703914(+) TATTTG/TAATAT 5 -- ut31 nc-transcript-variant0--------
    rs1892667561,2
    --44704032(+) CCACAA/GAGGCA 5 -- ut31 nc-transcript-variant0--------
    rs1478643241,2
    C--44704187(+) CACGC-/TTTA  
            
    TTTGA
    5 -- ut31 nc-transcript-variant0--------
    rs11285531,2
    C,F,O,A,H--44704206(-) GTTTTT/CTATCT 5 -- nc-transcript-variantut3124Minor allele frequency- C:0.43MN NS EA NA CSA WA 2812
    rs100106061,2
    C--44704276(+) ACTTCA/GTATTA 5 -- nc-transcript-variantut310--------
    rs1399060291,2
    C--44704278(+) TTCGTA/TTTATT 5 -- ut31 nc-transcript-variant0--------
    rs1864024831,2
    --44704422(+) GGGACA/GTGAAC 5 -- ut31 nc-transcript-variant0--------

    HapMap Linkage Disequilibrium report for GNPDA2 (44703885 - 44728612 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for GNPDA2:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv4319CNV Loss18451855

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 613222    OMIM disorders: --

    5 diseases for GNPDA2:    About MalaCards
    obesity    anorexia nervosa    pneumonia    diabetes mellitus
    neuronitis


    GNPDA2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): GNPDA2
    Human Genome Epidemiology (HuGE) Navigator: GNPDA2 (24 documents)

    Export disorders for GNPDA2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GNPDA2 gene, integrated from 9 sources (see all 62):
    (articles sorted by number of sources associating them with GNPDA2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Two mammalian glucosamine-6-phosphate deaminases: a structural and genetic study. (PubMed id 12965206)1, 2, 3 Arreola R.... Horjales E. (2003)
    2. Association between obesity and polymorphisms in SEC1 6B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population. (PubMed id 19851340)1, 4, 9 Hotta K....Nakamura Y. (2009)
    3. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. (PubMed id 20935630)1, 4 Speliotes E.K....Loos R.J. (2010)
    4. Genetic susceptibility to obesity and related traits in childhood and adolescence: influence of loci identified by genome-wide assoc iation studies. (PubMed id 20724581)1, 4 den Hoed M....Loos R.J. (2010)
    5. Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth. (PubMed id 20520848)1, 4 Elks C.E....Ong K.K. (2010)
    6. Evaluating the discriminative power of multi-trait ge netic risk scores for type 2 diabetes in a northern Swedish population. (PubMed id 20571754)1, 4 Fontaine-Bisson B....Franks P.W. (2010)
    7. Implication of genetic variants near NEGR1, SEC16B, T MEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, a nd KCTD15 with obesity and type 2 diabetes in 7705 Chinese. (PubMed id 20215397)1, 4 Ng M.C....Ma R.C. (2010)
    8. Are recently identified genetic variants regulating B MI in the general population associated with anorexia nervosa? (PubMed id 19746409)1, 4 Brandys M.K....Adan R.A. (2010)
    9. Analyses of shared genetic factors between asthma and obesity in children. (PubMed id 20816195)1, 4 MelAcn E....Lasky-Su J. (2010)
    10. Obesity and diabetes genetic variants associated with gestational weight gain. (PubMed id 20816152)1, 4 Stuebe A.M....Siega-Riz A.M. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 132789 HGNC: 21526 AceView: GNPDA2.1 Ensembl:ENSG00000163281 euGenes: HUgn132789
    ECgene: GNPDA2 Kegg: 132789 H-InvDB: GNPDA2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GNPDA2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for GNPDA2 gene:
    Search GeneIP for patents involving GNPDA2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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