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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GNG7 Gene

protein-coding   GIFtS: 59
GCID: GC19M002511

guanine nucleotide binding protein (G protein), gamma 7

 Explore 8 diseases affiliated with
GNG7 via our new
 Human Malady Compendium 
Biological research products
for GNG7
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Guanine Nucleotide Binding Protein (G Protein), Gamma 71 2
FLJ000581
Guanine Nucleotide-Binding Protein G(I)/G(S)/G(O) Subunit Gamma-72
GNGT73

External Ids:    HGNC: 44101   Entrez Gene: 27882   Ensembl: ENSG000001765337   OMIM: 6044305   UniProtKB: O602623   

Export aliases for GNG7 gene to outside databases

Previous GC identifers: GC19M002577 GC19M002454 GC19M002463 GC19M002464 GC19M002465 GC19M002283


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: GBG7_HUMAN, O60262
Function: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various
transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of
GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in
certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf)
subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum (By similarity)

summary for GNG7:
Heterotrimeric G proteins are membrane bound GTPases that are linked to 7-TM receptors. Each G protein
contains an alpha-, beta- and gamma-subunit and is bound to GDP in the 'off' state. Ligand-receptor binding
results in detachment of the G protein, switching it to an 'on' state and permitting Galpha activation of
second messenger signalling cascades. There are several types of Galpha proteins; in addition, some
Gbetagamma subunits have active functions. Gbetagamma coupled to H1 receptors can activate PLA2 and
Gbetagamma coupled to M1 receptors can activate KIR channels.

Gene Wiki entry for GNG7


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011255.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GNG7 gene promoter:
         RFX1   USF1   POU2F1   USF-1   POU2F1a   USF2   USF-1:USF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGNG7 promoter sequence
   Search SABiosciences Chromatin IP Primers for GNG7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GNG7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.3   Ensembl cytogenetic band:  19p13.3   HGNC cytogenetic band: 19p13.3

GNG7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GNG7 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M002511:  view genomic region     (about GC identifiers)

Start:
2,511,217 bp from pter      End:
2,702,707 bp from pter
Size:
191,491 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: GBG7_HUMAN, O60262 (See protein sequence)
Recommended Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 precursor  
Size: 68 amino acids; 7522 Da
Subunit: G proteins are composed of 3 units, alpha, beta and gamma
Subcellular location: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential)
Secondary accessions: B2R496

Explore the universe of human proteins at neXtProt for GNG7: NX_O60262

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O60262

  • GNG7 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_443079.1  
    ENSEMBL proteins: 
     ENSP00000371594   ENSP00000468650  
    Reactome Protein details: O60262
    Human Recombinant Protein Products: 
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    Browse Proteins at Uscn

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005834heterotrimeric G-protein complex IEA--
    GO:0005886plasma membrane TAS--


    GNG7 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    GNG7 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR001770 Gprotein-gamma
     IPR015898 G-protein_gamma-like_dom

    Graphical View of Domain Structure for InterPro Entry O60262

    ProtoNet protein and cluster: O60262

    1 Blocks protein family: IPB001770 Gamma G-protein (transducin) signature

    UniProtKB/Swiss-Prot: GBG7_HUMAN, O60262
    Similarity: Belongs to the G protein gamma family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: GBG7_HUMAN, O60262
    Function: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various
    transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of
    GDP by GTP, and for G protein-effector interaction. Plays a role in the regulation of adenylyl cyclase signaling in
    certain regions of the brain. Plays a role in the formation or stabilzation of a G protein heterotrimer (G(olf)
    subunit alpha-beta-gamma-7) that is required for adenylyl cyclase activity in the striatum (By similarity)

    miRNA
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    hsa-miR-141 hsa-miR-135b hsa-miR-4254 hsa-miR-615-5p hsa-miR-3116 hsa-miR-200a hsa-miR-135a
    SwitchGear 3'UTR luciferase reporter plasmidGNG7 3' UTR sequence
    Inhib. RNA
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004871signal transducer activity IEA--


    GNG7 for ontologies           About GeneDecksing


    3 GenomeRNAi human phenotypes for GNG7:
     G0/1 arrest  Increased G1 DNA content  Increased gamma-H2AX phosphory 

    Animal Models:
         Mouse knock-out Gng7tm1Lex for GNG7
         6 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Gng7):
     behavior/neurological  cellular  homeostasis/metabolism  mortality/aging  nervous system 
     no phenotypic analysis 

    GNG7 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/60 super-pathways (see all 60About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1G beta:gamma signalling through PLC beta
    8/12 pathways (see all 12)
    G beta:gamma signalling through PLC beta1.00
    G beta:gamma signalling through PI3Kgamma0.61
    Presynaptic function of Kainate receptors0.95
    Inhibition of Insulin Secretion by Adrenaline/Noradrenaline0.55
    Prostacyclin signalling through prostacyclin receptor0.77
    G-protein activation0.55
    G-protein beta:gamma signalling0.71
    Glucagon-type ligand receptors0.52
    2Development Angiotensin activation of ERK
    8/9 pathways (see all 9)
    Development Angiotensin activation of ERK1.00
    Development G-Proteins mediated regulation MARK-ERK signaling0.66
    Development_Angiotensin activation of ERK0.98
    Development_EDNRB signaling0.54
    Development_ACM2 and ACM4 activation of ERK0.74
    Development EDNRB signaling0.54
    Development ACM2 and ACM4 activation of ERK0.74
    Cholinergic synapse0.30
    3Development_A3 receptor signaling
    Development_A3 receptor signaling1.00
    Development A1 receptor signaling0.65
    Development A3 receptor signaling1.00
    G-protein signaling_G-Protein alpha-q signaling cascades0.53
    Development_A1 receptor signaling0.65
    G-protein signaling G-Protein alpha-q signaling cascades0.53
    4G-protein signaling_G-Protein alpha-i signaling cascades
    G-protein signaling_G-Protein alpha-i signaling cascades1.00
    Development Beta-adrenergic receptors regulation of ERK0.55
    G-protein signaling G-Protein alpha-i signaling cascades1.00
    G-protein signaling_G-Protein alpha-s signaling cascades0.44
    Development_Beta-adrenergic receptors regulation of ERK0.55
    G-protein signaling G-Protein alpha-s signaling cascades0.44
    5Development_Dopamine D2 receptor transactivation of EGFR
    Development_Dopamine D2 receptor transactivation of EGFR1.00
    Development Alpha-2 adrenergic receptor activation of ERK0.66
    Development Dopamine D2 receptor transactivation of EGFR1.00
    Chemotaxis_CXCR4 signaling pathway0.48
    Development_Alpha-2 adrenergic receptor activation of ERK0.66
    Chemotaxis CXCR4 signaling pathway0.48

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    5/31 EMD Millipore Pathways for GNG7 (see all 31)
        Chemotaxis CXCR4 signaling pathway
    Translation Translation regulation by Alpha-1 adrenergic receptors
    Development Activation of ERK by Alpha-1 adrenergic receptors
    Cytoskeleton remodeling Role of PKA in cytoskeleton reorganisation
    Development A1 receptor signaling

    5/47 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for GNG7 (see all 47)
        Molecular Mechanisms of Cancer
    Intracellular Calcium Signaling
    CDK5 Pathway
    JNK Pathway
    ERK5 Signaling

    5/34 GeneGo (Thomson Reuters) Pathways for GNG7 (see all 34)
        Signal transduction cAMP signaling
    G-protein signaling Regulation of p38 and JNK signaling mediated by G-proteins
    G-protein signaling G-Protein alpha-i signaling cascades
    Inhibitory action of Lipoxins and Resolvin E1 on neutrophil functions
    Signal transduction Activation of PKC via G-Protein coupled receptor

    3 BioSystems Pathways for GNG7 
        Calcium Regulation in the Cardiac Cell
    G Protein Signaling Pathways
    Myometrial Relaxation and Contraction Pathways

    5/48        Reactome Pathways for GNG7 (see all 48)
        G alpha (12/13) signalling events
    Platelet homeostasis
    G protein gated Potassium channels
    G alpha (z) signalling events
    Inwardly rectifying K+ channels

    1 PharmGKB Pathway for GNG7
        Beta-agonist/Beta-blocker Pathway, Pharmacodynamics

    3         Kegg Pathways  (Kegg details for GNG7):
        Chemokine signaling pathway
    Glutamatergic synapse
    Cholinergic synapse


    GNG7 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GNG7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/70 Interacting proteins for GNG7 (O602622, 3 ENSP000003715944) via UniProtKB, MINT, STRING, and/or I2D (see all 70)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACP6Q9NPH02, 3, ENSP000003582414MINT-65570 I2D: score=5 STRING: ENSP00000358241
    MPP3Q133682, 3MINT-64781 I2D: score=5 
    GNB1P628733, ENSP000003678724I2D: score=2 STRING: ENSP00000367872
    GNB3P165203, ENSP000002292644I2D: score=2 STRING: ENSP00000229264
    GNB4Q9HAV03, ENSP000002325644I2D: score=2 STRING: ENSP00000232564
    About this table

    Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001662behavioral fear response IEA--
    GO:0006112energy reserve metabolic process TAS--
    GO:0007168receptor guanylyl cyclase signaling pathway IEA--
    GO:0007186G-protein coupled receptor signaling pathway IEA--
    GO:0007268synaptic transmission TAS--


    GNG7 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Compounds for GNG7 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    GalleinInhibitor of betagamma signaling[2103-64-2]
    GRK2iGRK2 inhibitory polypeptide. Gbetagamma antagonist[148505-03-7]

    3 HMDB Compounds for GNG7    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine diphosphate5'-GDP (see all 10)146-91-8--
    Guanosine monophosphate5'-GMP (see all 14)85-32-5--
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--
    Search CenterWatch for drugs/clinical trials and news about GNG7 / GBG7 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GNG7 gene: 
    NM_052847.2  

    Unigene Clusters for GNG7:

    Guanine nucleotide binding protein (G protein), gamma 7
    Hs.515544  [show with all ESTs], Hs.735237  [show with all ESTs]
    Unigene Representative Sequences: AK024465, DA187125
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000382159(uc002lwd.2) ENST00000587867

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    Additional cDNA sequence: AF493874.1 

    4 DOTS entries:

    DT.446523  DT.121409284  DT.87010675  DT.99941089 

    24/95 AceView cDNA sequences (see all 95):

    T16705 BC010463 AF493874 AL039869 BM676827 BM701615 BU739827 BU738680 
    AL039870 BM720289 BM126333 CK818935 BI547909 BC037318 AW275324 BG708302 
    CB565925 CF456469 AK123863 BX279759 BX955400 CF541254 H46880 BX486290 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GNG7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AAGTTTTTTG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See GNG7 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GNG7

    SOURCE GeneReport for Unigene clusters: Hs.515544 Hs.735237

    UniProtKB/Swiss-Prot: GBG7_HUMAN, O60262
    Tissue specificity: Expressed in a variety of tissues. Down-regulated in pancreatic and esophageal cancer

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GNG7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for GNG7 gene from 2/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves LOC1008589761 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit more 82.84(n)
    91.18(a)
      100858976  XM_003643416.1  XP_003643464.1 
    zebrafish
    (Danio rerio)
    Actinopterygii gng71 guanine nucleotide binding protein (G protein), gamma more 78.92(n)
    94.12(a)
      436670  NM_001002397.1  NP_001002397.1 


    ENSEMBL Gene Tree for GNG7 (if available)
    TreeFam Gene Tree for GNG7 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GNG7 gene
    GNG22  GNG102  GNG32  GNG82  GNG52  GNG5P22  GNG42  GNG122  
    11 SIMAP similar genes for GNG7 using alignment to 2 protein entries:     GBG7_HUMAN (see all proteins):
    DKFZp762E193    GNG12    GNG8    GNG2    GNG4    GNG3
    GNG5    GNG10    GNG11    GNGT1    GNGT2

    GNG7 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/4437 NCBI SNPs in GNG7 are shown (see all 4437    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1927577691,2
    --2510957(+) GCCACC/TGCGCC 1 -- int10--------
    rs349659921,2
    C,--2510963(+) GCGCCC/TGGCCC 1 -- int12Minor allele frequency- T:0.05NA 122
    rs1488107101,2
    --2510967(+) CCGGCA/CCCTCC 1 -- int10--------
    rs1434571101,2
    --2510968(+) CGGCCC/TCTCCT 1 -- int10--------
    rs735144011,2
    C,--2510999(+) NNNNAG/TCCCAC 1 -- int13Minor allele frequency- T:0.14WA NA 240
    rs1483677021,2
    --2511091(+) GTGGAC/TGGGAT 1 -- int10--------
    rs1432985961,2
    --2511151(+) CTTGCA/CTGCTA 1 -- int10--------
    rs1475431331,2
    --2511180(+) AGGCCC/TGGGCC 1 -- int10--------
    rs1384707601,2
    --2511255(+) ATTCAC/TGTGGT 1 -- ut310--------
    rs1170306991,2
    F,--2511395(+) AGGCGG/CCGGCT 1 -- ut311Minor allele frequency- C:0.03NA 120

    HapMap Linkage Disequilibrium report for GNG7 (2511217 - 2702707 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 5 variations for GNG7
         3 CNVs: 67435 5069 73283
         2 Indels: 45746 26236

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    GNG7 for disorders           About GeneDecksing

    OMIM gene information: 604430    OMIM disorders: --

    8 diseases for GNG7:    About MalaCards
    bloom syndrome    esophageal cancer    esophagitis    pancreatic cancer
    pancreatitis    huntington's disease    colorectal cancer    breast cancer

    Human Genome Epidemiology (HuGE) Navigator: GNG7 (1 document)

    Export disorders for GNG7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GNG7 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with GNG7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and cloning of human G-protein gamma 7, down-regulated in pancreatic cancer. (PubMed id 9600093)1, 2, 3 Shibata K.... Akiyoshi T. (1998)
    2. Clinical significance of the reduced expression of G protein gamma 7 (GNG7) in oesophageal cancer. (PubMed id 18219292)1, 2 Ohta M....Mori M. (2008)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
    6. Loss of protein expression and recurrent DNA hypermeth ylation of the GNG7 gene in squamous cell carcinoma of the head and neck. (PubMed id 22183866)1 Hartmann S....Giefing M. (2012)
    7. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    8. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    9. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    10. Human G-protein gamma 7 in extrahepatic cholangiocarc inoma and its clinicopathological significance. (PubMed id 20543539)1 Wang M....Wang Y. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 2788 HGNC: 4410 AceView: GNG7 Ensembl:ENSG00000176533 euGenes: HUgn2788
    ECgene: GNG7 Kegg: 2788 H-InvDB: GNG7

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GNG7 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for GNG7 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for GNG7 gene:
    Search GeneIP for patents involving GNG7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

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