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GNG13 Gene

protein-coding   GIFtS: 55
GCID: GC16M000848

Guanine Nucleotide Binding Protein (G Protein), Gamma 13

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Guanine Nucleotide Binding Protein (G Protein), Gamma 131 2     G Gamma Subunit, Clone:H2-352
clone:h2-351     Guanine Nucleotide Binding Protein 13, Gamma2
G Gamma Subunit1     Guanine Nucleotide-Binding Protein G(I)/G(S)/G(O) Subunit Gamma-132
G(gamma)132     h2-352

External Ids:    HGNC: 141311   Entrez Gene: 517642   Ensembl: ENSG000001275887   OMIM: 6072985   UniProtKB: Q9P2W33   

Export aliases for GNG13 gene to outside databases

Previous GC identifers: GC16M000867 GC16M000788 GC16M000770


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for GNG13 Gene:
Heterotrimeric G proteins, which consist of alpha (see MIM 139320), beta (see MIM 139380), and gamma subunits,
function as signal transducers for the 7-transmembrane-helix G protein-coupled receptors. GNG13 is a gamma
subunit that is expressed in taste, retinal, and neuronal tissues and plays a key role in taste transduction (Li
et al., 2006 (PubMed 16473877)).(supplied by OMIM, Oct 2009)

GeneCards Summary for GNG13 Gene:
GNG13 (guanine nucleotide binding protein (G protein), gamma 13) is a protein-coding gene. GO annotations related to this gene include signal transducer activity.

UniProtKB/Swiss-Prot: GBG13_HUMAN, Q9P2W3
Function: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various
transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement
of GDP by GTP, and for G protein-effector interaction

summary for GNG13 Gene:
Heterotrimeric G proteins are membrane bound GTPases that are linked to 7-TM receptors. Each G protein
contains an alpha-, beta- and gamma-subunit and is bound to GDP in the 'off' state. Ligand-receptor binding
results in detachment of the G protein, switching it to an 'on' state and permitting Galpha activation of
second messenger signalling cascades. There are several types of Galpha proteins; in addition, some
Gbetagamma subunits have active functions. Gbetagamma coupled to H1 receptors can activate PLA2 and
Gbetagamma coupled to M1 receptors can activate KIR channels.

Gene Wiki entry for GNG13 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000016.9  NC_018927.2  NT_010393.17  
Regulatory elements:
   Regulatory transcription factor binding sites in the GNG13 gene promoter:
         Max1   AREB6   AML1a   POU2F1   POU2F1a   LUN-1   Nkx2-5   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGNG13 promoter sequence
   Search Chromatin IP Primers for GNG13

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat GNG13


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p13.3   Ensembl cytogenetic band:  16p13.3   HGNC cytogenetic band: 16p13.3

GNG13 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GNG13 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M000848:  view genomic region     (about GC identifiers)

Start:
848,041 bp from pter      End:
850,733 bp from pter
Size:
2,693 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: GBG13_HUMAN, Q9P2W3 (See protein sequence)
Recommended Name: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 precursor  
Size: 67 amino acids; 7949 Da
Subunit: G proteins are composed of 3 units, alpha, beta and gamma
Secondary accessions: B2R5C8 Q52LX0 Q9UJJ3

Explore the universe of human proteins at neXtProt for GNG13: NX_Q9P2W3

Explore proteomics data for GNG13 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See GNG13 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_057625.1  
    ENSEMBL proteins: 
     ENSP00000248150  
    Reactome Protein details: Q9P2W3

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR001770 Gprotein-gamma
     IPR015898 G-protein_gamma-like_dom

    Graphical View of Domain Structure for InterPro Entry Q9P2W3

    ProtoNet protein and cluster: Q9P2W3

    1 Blocks protein domain: IPB001770 Gamma G-protein (transducin) signature

    UniProtKB/Swiss-Prot: GBG13_HUMAN, Q9P2W3
    Similarity: Belongs to the G protein gamma family


    Find genes that share domains with GNG13           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GBG13_HUMAN, Q9P2W3
    Function: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various
    transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement
    of GDP by GTP, and for G protein-effector interaction

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004871signal transducer activity IEA--
    GO:0031681G-protein beta-subunit binding IPI12606627
         
    Find genes that share ontologies with GNG13           About GenesLikeMe


    Phenotypes:
         5 GenomeRNAi human phenotypes for GNG13:
     Decreased Salmonella enterica   Decreased Salmonella enterica   Decreased Salmonella enterica   Decreased Salmonella-containin 
     Increased gamma-H2AX phosphory 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Gng13):
     mortality/aging  nervous system  taste/olfaction 

    Find genes that share phenotypes with GNG13           About GenesLikeMe

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for GNG13

    miRNA
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    2 qRT-PCR Assays for microRNAs that regulate GNG13:
    hsa-miR-142-5p hsa-miR-340
    SwitchGear 3'UTR luciferase reporter plasmidGNG13 3' UTR sequence
    Inhib. RNA
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    GBG13_HUMAN, Q9P2W3: Cell membrane; Lipid-anchor; Cytoplasmic side (Potential)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    cytosol3
    extracellular1
    mitochondrion1
    nucleus1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005834heterotrimeric G-protein complex IEA--
    GO:0005886plasma membrane TAS--

    Find genes that share ontologies with GNG13           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for GNG13 About   (see all 58)  
    See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1ADP signalling through P2Y purinoceptor 12
    G-protein beta-gamma signalling0.90
    G-protein activation0.74
    G beta-gamma signalling through PI3Kgamma0.90
    Thrombin signalling through proteinase activated receptors (PARs)0.69
    Signal amplification0.79
    Activation of Kainate Receptors upon glutamate binding0.68
    ADP signalling through P2Y purinoceptor 10.79
    Inhibition of Insulin Secretion by Adrenaline/Noradrenaline0.64
    2Regulation of Water Balance by Renal Aquaporins
    Regulation of Water Balance by Renal Aquaporins0.85
    Glucagon signaling in metabolic regulation0.70
    Aquaporin-mediated transport0.85
    Cytoskeleton remodeling Role of PKA in cytoskeleton reorganisation0.40
    3fMLP Pathway
    fMLP Pathway0.43
    Alpha-Adrenergic Signaling0.38
    Signal transduction Activation of PKC via G Protein coupled receptor0.42
    Huntington's Disease Pathway0.30
    4EphB-EphrinB Signaling
    EphB-EphrinB Signaling0.58
    Cytoskeleton remodeling Reverse signaling by ephrin B0.34
    Ephrin-Eph Signaling0.58
    5Ca-dependent events
    Opioid Signalling0.54
    Signal transduction Calcium signaling0.35


    Find genes that share SuperPaths with GNG13           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for GNG13 (see all 48)
        Molecular Mechanisms of Cancer
    Intracellular Calcium Signaling
    CDK5 Pathway
    JNK Pathway
    ERK5 Signaling

    Selected GeneGo (Thomson Reuters) Pathways for GNG13 (see all 34)
        Signal transduction cAMP signaling
    G-protein signaling Regulation of p38 and JNK signaling mediated by G-proteins
    G-protein signaling G-Protein alpha-i signaling cascades
    Inhibitory action of Lipoxins and Resolvin E1 on neutrophil functions
    Signal transduction Activation of PKC via G-Protein coupled receptor

    4 BioSystems Pathways for GNG13
        Myometrial Relaxation and Contraction Pathways
    G Protein Signaling Pathways
    Calcium Regulation in the Cardiac Cell
    Endothelin


    Selected Reactome Pathways for GNG13 (see all 21)
        G alpha (12/13) signalling events
    G alpha (z) signalling events
    G-protein activation
    Ca2+ pathway
    Thromboxane signalling through TP receptor


    Selected Kegg Pathways  (Kegg details for GNG13) (see all 13):
        Ras signaling pathway
    Chemokine signaling pathway
    PI3K-Akt signaling pathway
    Circadian entrainment
    Retrograde endocannabinoid signaling

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for GNG13
    Interactions:

        GeneGlobe Interaction Network for GNG13

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for GNG13 (Q9P2W33 ENSP000002481504) via UniProtKB, MINT, STRING, and/or I2D (see all 73)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GNB1P628733, ENSP000003678724I2D: score=2 STRING: ENSP00000367872
    GNB4Q9HAV03, ENSP000002325644I2D: score=2 STRING: ENSP00000232564
    DLG1Q129593, ENSP000003457314I2D: score=1 STRING: ENSP00000345731
    GNAT3A8MTJ33, ENSP000003813394STRING: ENSP00000381339 I2D: score=1 
    LIN7BQ9HAP63, ENSP000002214594I2D: score=1 STRING: ENSP00000221459
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006112energy reserve metabolic process TAS--
    GO:0007186G-protein coupled receptor signaling pathway ----
    GO:0007200phospholipase C-activating G-protein coupled receptor signaling pathway IEA--
    GO:0044281small molecule metabolic process TAS--
    GO:0050909sensory perception of taste IEA--

    Find genes that share ontologies with GNG13           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Compounds for GNG13 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    GalleinInhibitor of betagamma signaling[2103-64-2]
    Suramin hexasodium saltNon-selective P2 antagonist[129-46-4]
    G-Protein antagonist peptideInhibits G protein activation by GPCRs[143675-79-0]
    8-Bromo-cGMP, sodium salt cGMP analog; activates PKG[51116-01-9]
    Pertussis Toxin Catalyzes ADP-ribosylation of Gi, Go and Gt [70323-44-3]

    3 HMDB Compounds for GNG13    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine diphosphate5'-GDP (see all 10)146-91-8--
    Guanosine monophosphate5'-GMP (see all 14)85-32-5--
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for GNG13 gene: 
    NM_016541.2  

    Unigene Cluster for GNG13:

    Guanine nucleotide binding protein (G protein), gamma 13
    Hs.247888  [show with all ESTs]
    Unigene Representative Sequence: NM_016541
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000248150(uc002ckh.4)
    miRNA
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    Additional mRNA sequence: 

    AB030207.1 AF493880.1 AK312139.1 AY029486.1 BC093760.1 BC095525.1 

    2 DOTS entries:

    DT.97840026  DT.99980110 

    15 AceView cDNA sequences:

    BQ185779 BQ187619 AF493880 AY029486 NM_016541 BX280627 AB030207 BQ638029 
    CB565919 H46116 H19926 BM931126 BM719734 BM726099 BM724869 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    GNG13 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CCCGGCCCCA
    GNG13 Expression
    About this image


    GNG13 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Brain (Nervous System)    fully expand to see all 9 entries
             Thalamus
     
     Ovary (Reproductive System)
             Pre-Granulosa Cells Primordial Follicle
     
     Eye (Sensory Organs)
             Mature Rod Bipolar Cells Inner Nuclear Layer
     
     Epithelial Cells
             Fetal Matrix Cells Hair Follicle
     
     Hair (Integumentary System)
             Fetal Matrix Cells Hair Follicle
    GNG13 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    GNG13 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.247888
        Custom PCR Arrays for GNG13
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for GNG13 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gng131 , 5 guanine nucleotide binding protein (G protein), gamma more1, 5 90.05(n)1
    95.52(a)1
      17 (12.82 cM)5
    643371  NM_022422.51  NP_071867.11 
     257171715 
    chicken
    (Gallus gallus)
    Aves GNG131 guanine nucleotide binding protein (G protein), gamma more 84.08(n)
    82.09(a)
      771014  NM_001267819.1  NP_001254748.1 
    African clawed frog
    (Xenopus laevis)
    Amphibia gng13-prov2 guanine nucleotide binding protein 13, gamma 78.05(n)    BC041247.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.141902 Transcribed sequence with moderate similarity to protein more 80.61(n)    BI429047.1 


    ENSEMBL Gene Tree for GNG13 (if available)
    TreeFam Gene Tree for GNG13 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for GNG13 gene
    1 SIMAP similar gene for GNG13 using alignment to 1 protein entry:     GBG13_HUMAN:
    GNG11

    Find genes that share paralogs with GNG13           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for GNG13 (see all 168)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs28910641,2
    C,F,A,H--848575(+) CGGGCA/GTGGGC 1 -- ut31 ese38Minor allele frequency- G:0.33WA NA CSA EA 371
    rs1440678031,2
    C--848642(+) GCTGGG/TCACAG 1 -- ut310--------
    rs2012957031,2
    C--848673(+) GGGGCC/TGGGCG 1 -- ut310--------
    rs1142603581,2
    C,F--848674(+) GGGCCG/TGGCGT 1 -- ut311Minor allele frequency- T:0.09WA 118
    rs1464519931,2
    C--848698(+) GGTGT-/GAGAGGG 1 -- ut310--------
    rs1469090741,2
    C,F--848717(+) GCGGGG/CCTCAC 1 -- ut312Minor allele frequency- C:0.01NA EU 5869
    rs360735411,2
    C,F,H--848755(-) AACAAC/TCCATG 2 N syn119Minor allele frequency- T:0.05NS EA NA WA EU 8217
    rs1999075421,2
    --848761(+) TTGTTC/TTTCAT 2 K syn10--------
    rs1868038171,2
    C--848772(+) CAGGTC/TGGGGT 2 N D mis10--------
    rs1446471921,2
    C,F--848781(+) GTTCAG/CGAAGG 2 /L /V mis11Minor allele frequency- C:0.00NA 4548

    HapMap Linkage Disequilibrium report for GNG13 (848041 - 850733 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for GNG13 (see all 20):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2422427CNV Duplication17116639
    dgv2501n71CNV Loss21882294
    dgv2499n71CNV Loss21882294
    dgv2475n71CNV Loss21882294
    dgv2500n71CNV Loss21882294
    nsv904796CNV Loss21882294
    nsv904797CNV Loss21882294
    nsv817712CNV Loss17921354
    nsv904844CNV Loss21882294
    nsv526903CNV Loss19592680

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 607298    OMIM disorders: --


    Find genes that share disorders with GNG13           About GenesLikeMe

    Human Genome Epidemiology (HuGE) Navigator: GNG13 (1 document)

    Export disorders for GNG13 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for GNG13 gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with GNG13)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium. (PubMed id 10570481)1, 2, 3 Huang L.... Margolskee R.F. (Nat. Neurosci. 1999)
    2. The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)1, 2 Martin J.... Pennacchio L.A. (Nature 2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16. (PubMed id 11157797)1, 2 Daniels R.J....Higgs D.R. (Hum. Mol. Genet. 2001)
    5. Association between common variation in genes encoding sweet taste signaling components and human sucrose perception. (PubMed id 20660057)1 Fushan A.A....Drayna D. (Chem. Senses 2010)
    6. Gbeta3 forms distinct dimers with specific Ggamma subunits and preferentially activates the beta3 isoform of phospholipase C. (PubMed id 19168127)1 Poon L.S....Wong Y.H. (Cell. Signal. 2009)
    7. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (Genome Res. 2006)
    8. Ggamma13 interacts with PDZ domain-containing proteins. (PubMed id 16473877)1 Li Z....Margolskee R.F. (J. Biol. Chem. 2006)
    9. Characterization of heterotrimeric G protein complexes in rice plasma membrane. (PubMed id 15078334)1 Kato C....Iwasaki Y. (Plant J. 2004)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51764 HGNC: 14131 AceView: GNG13 Ensembl:ENSG00000127588 euGenes: HUgn51764
    ECgene: GNG13 Kegg: 51764 H-InvDB: GNG13

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for GNG13 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for GNG13 gene:
    Search GeneIP for patents involving GNG13

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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