GNB3 Gene

Aliases
for GNB3 gene

Previous GC identifers: GC12M007019 GC12M007103 GC12P006828 GC12P006819 GC12P006977 GC12P006981 GC12P006808 GC12P006989 GC12P007001 GC12P007010 GC12P007021

Summaries
for GNB3 gene

Genomic Views
for GNB3 gene

RefSeq DNA sequence:

NC_000012.11  NC_018923.1  NT_009759.16  

SwitchGear Promoter luciferase reporter plasmid: GNB3 promoter sequence

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GNB3

GNB3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P007045:  view genomic region     (about GC identifiers)

Proteins
for GNB3 gene

Explore the universe of human proteins at neXtProt for GNB3: NX_P16520

Post-translational modifications:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate: GNB3 OriGene Custom Protein Services for GNB3
	GenScript Custom Purified and Recombinant Proteins Services for GNB3
	Novus Biologicals GNB3 Protein Novus Biologicals GNB3 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Browse Proteins at Uscn

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

	EMD Millipore Mono- and Polyclonal Antibodies for the study of GNB3
	Browse R&D Systems for Antibodies
	Cell Signaling Technology (CST) Antibodies for GNB3
	Browse OriGene Antibodies OriGene Custom Antibody Services for GNB3
	GenScript Custom Superior Antibodies Services for GNB3
	Novus Biologicals GNB3 Antibodies
	Abcam antibodies for GNB3
	Browse Antibodies at Uscn
	ThermoFisher Antibodies for GNB3

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for GNB3
	Browse Enzo Life Sciences for kits & assays
	Browse ELISAs and CLIAs at Uscn

Protein Domains /
Families
for GNB3 gene

ProtoNet protein and cluster: P16520

Function
for GNB3 gene

miRNA Products:		OriGene 3'-UTR Clone: GNB3 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GNB3
		3 QIAGEN miScript miRNA Assays for microRNAs that regulate GNB3:
		hsa-miR-186* hsa-miR-3675-5p hsa-miR-486-3p
		SwitchGear 3'UTR luciferase reporter plasmid: GNB3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GNB3 (see all 7) OriGene shRNA RFP: GNB3 OriGene siRNA: GNB3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GNB3

Gene Editing Products:

DNA2.0 Custom Protein Engineering Service for GNB3

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GNB3 (see all 7) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GNB3 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: GNB3 (NM_002075)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for GNB3
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GNB3

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for GNB3
		Search LifeMap BioReagents cell lines for GNB3

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GNB3

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

(inferred from 1 allele) (MGI details for Gnb3)

Pathways & Interactions
for GNB3 gene

	Super-pathway	contained gene-specific pathways
1	G beta:gamma signalling through PLC beta	8/13 pathways (see all 13) G beta:gamma signalling through PLC beta 1.00 Inhibition of Insulin Secretion by Adrenaline/Noradrenaline 0.55 Presynaptic function of Kainate receptors 0.95 G-protein activation 0.55 Prostacyclin signalling through prostacyclin receptor 0.77 Glucagon-type ligand receptors 0.52 G-protein beta:gamma signalling 0.71 G-Protein Signaling through Tubby Protein 0.38
2	Development Angiotensin activation of ERK	8/9 pathways (see all 9) Development Angiotensin activation of ERK 1.00 Development G-Proteins mediated regulation MARK-ERK signaling 0.66 Development_Angiotensin activation of ERK 0.98 Development_EDNRB signaling 0.54 Development_ACM2 and ACM4 activation of ERK 0.74 Development EDNRB signaling 0.54 Development ACM2 and ACM4 activation of ERK 0.74 Cholinergic synapse 0.30
3	Development_A3 receptor signaling	Development_A3 receptor signaling 1.00 Development A1 receptor signaling 0.65 Development A3 receptor signaling 1.00 G-protein signaling_G-Protein alpha-q signaling cascades 0.53 Development_A1 receptor signaling 0.65 G-protein signaling G-Protein alpha-q signaling cascades 0.53
4	G-protein signaling_G-Protein alpha-i signaling cascades	G-protein signaling_G-Protein alpha-i signaling cascades 1.00 Development Beta-adrenergic receptors regulation of ERK 0.55 G-protein signaling G-Protein alpha-i signaling cascades 1.00 G-protein signaling_G-Protein alpha-s signaling cascades 0.44 Development_Beta-adrenergic receptors regulation of ERK 0.55 G-protein signaling G-Protein alpha-s signaling cascades 0.44
5	Development_Dopamine D2 receptor transactivation of EGFR	Development_Dopamine D2 receptor transactivation of EGFR 1.00 Development Alpha-2 adrenergic receptor activation of ERK 0.66 Development Dopamine D2 receptor transactivation of EGFR 1.00 Chemotaxis_CXCR4 signaling pathway 0.48 Development_Alpha-2 adrenergic receptor activation of ERK 0.66 Chemotaxis CXCR4 signaling pathway 0.48

5/31 EMD Millipore Pathways for GNB3

	Chemotaxis CXCR4 signaling pathway
	Translation Translation regulation by Alpha-1 adrenergic receptors
	Development Activation of ERK by Alpha-1 adrenergic receptors
	Cytoskeleton remodeling Role of PKA in cytoskeleton reorganisation
	Development A1 receptor signaling

5/71 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for GNB3

	Molecular Mechanisms of Cancer
	Intracellular Calcium Signaling
	CDK5 Pathway
	JNK Pathway
	ERK5 Signaling

2 Cell Signaling Technology (CST) Pathways for GNB3

	Ca, cAMP and Lipid Signaling
	Neuroscience

5/34 GeneGo (Thomson Reuters) Pathways for GNB3

	Signal transduction cAMP signaling
	G-protein signaling Regulation of p38 and JNK signaling mediated by G-proteins
	G-protein signaling G-Protein alpha-i signaling cascades
	Inhibitory action of Lipoxins and Resolvin E1 on neutrophil functions
	Signal transduction Activation of PKC via G-Protein coupled receptor

5 BioSystems Pathways for GNB3

	Myometrial Relaxation and Contraction Pathways
	SIDS Susceptibility Pathways
	G Protein Signaling Pathways
	Calcium Regulation in the Cardiac Cell
	Visual signal transduction- Cones

5/48        Reactome Pathways for GNB3

	G alpha (12/13) signalling events
	Platelet homeostasis
	G protein gated Potassium channels
	G alpha (z) signalling events
	Inwardly rectifying K+ channels

2 PharmGKB Pathways for GNB3

	Beta-agonist/Beta-blocker Pathway, Pharmacodynamics
	Platelet Aggregation Inhibitor Pathway, Pharmacodynamics

4         Kegg Pathways  (Kegg details for GNB3)

	Chemokine signaling pathway
	Glutamatergic synapse
	Cholinergic synapse
	Taste transduction

Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

Drugs & Compounds
for GNB3 gene

Transcripts
for GNB3 gene

Expression
for GNB3 gene

GNB3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTTTCTCCTT

1 LifeMap In Vivo Development Anatomical Compartment/Cell
	Tissue Anatomical Compartment Cell			Category (developmental path)
	EyeInner Nuclear LayerMature Rod Bipolar Cells			Bipolar, Retina
Expression: Positive    Negative     Selective marker Experimental details: Curated     Microarrays     In-situ hybridization
Stem Cell Differentiation: 1 LifeMap Cell
	Name			Category
	Midbrain dopaminergic-like neurons (Generation of midbra...)

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GNB3 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT2 qPCR Primer Assay in human, mouse, rat GNB3
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GNB3
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GNB3

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GNB3

Orthologs
for GNB3 gene

Paralogs
for GNB3 gene

Paralogs for GNB3 gene

GNB2²  GNB1²  WDR47²  GNB4²  GNB5²  

8 SIMAP similar genes for GNB3 using alignment to 8 protein entries:     GBB3_HUMAN (see all proteins):

GNB1    GNB4    GNB2    GNB5    WDR61    PF20

WDR82    GNB2L1

GNB3 for paralogs           About GeneDecksing

Genomic Variants
for GNB3 gene

10/189 NCBI SNPs in GNB3 are shown (see all 189)     About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 12 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs774106211,2		--	6801362(+)	ATTGTA/GGGAAG	1	--	us2k1		1		WA	118
rs38092471,2	C,	--	6802550(+)	GCCTGG/CGGAGC	1	--	us2k1		2		CSA WA	120
rs38092501,2	C,F,H,	--	6802734(+)	CTCTCA/CGCCAG	1	--	us2k1		9		NS EA CSA WA	1292
rs774194221,2		--	6803138(+)	GGGTCC/GCCTGT	1	--	ut51		0	--	--	--	--
rs1118310931,2		--	6803353(+)	TCCTGG/TCCTGG	1	--	int1		1		CSA	2
rs454538001,2	C,	--	6803600(+)	TCTCTA/GTGGCC	1	--	int1		4		WA CSA EA	242
rs20710571,2	C,	--	6803775(+)	CCGCCG/AGTCGG	1	--	ut51		1		NA	2
rs133064091,2	H	--	6804085(+)	GGCACG/AAAGGG	1	--	int1		4		NS EA	416
rs732587951,2	C,	--	6804696(+)	GATGCG/AAAAGA	1	--	int1		2		WA	120
rs1129631091,2	F,	--	6805036(+)	AATACC/ATGATT	1	--	int1		2		CSA	4

HapMap Linkage Disequilibrium report for GNB3 (6949118 - 6956557 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for GNB3: --
Human Gene Mutation Database (HGMD): GNB3

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GNB3

DNA2.0 Custom Variant and Variant Library Synthesis for GNB3

Disorders / Diseases
for GNB3 gene

20/83 diseases for GNB3

10/31 Novoseek disease relationships for GNB3 gene (see all 31)    About this table

Publications
for GNB3 gene

PubMed articles for GNB3 gene, integrated from 9 sources (see all 402) (see top 10): (articles sorted by number of sources associating them with GNB3)

Utopia: connect your pdf to the dynamic world of online information

1. The 825C>T polymorphism of the G-protein beta-3 subunit gene (GNB3) and breast cancer. (PubMed id 15019160)^{1, 4, 9} Krippl P....Samonigg H. (2004)
2. G protein beta 3 gene: structure, promoter, and additional polymorphisms. (PubMed id 10904009)^{1, 2, 9} Rosskopf D.... Siffert W. (2000)
3. [Association between G-protein beta3 subunit (GNB(3)) gene C825T polymorphism, hypertension, insulin resistance and obesity] (PubMed id 12930636)^{1, 4, 9} Chen Y.Y....Hui R.T. (2003)
4. Heterogeneity in hand veins responses to acetylcholine is not associated with polymorphisms in the G-protein beta3-subunit (C825T) and endothelial nitric oxide synthase (G894T) genes but with serum low density lipoprotein cholesterol. (PubMed id 11434508)^{1, 4, 9} Grossmann M....Kirch W. (2001)
5. Association of G-protein beta-3 subunit gene (GNB3) T825 allele with Type II diabetes. (PubMed id 15855877)^{1, 4, 9} Kiani J.G....Frossard P.M. (2005)
6. Association between a G-protein beta 3 subunit gene polymorphism and the symptomatology and treatment responses of major depressive disorders. (PubMed id 14647404)^{1, 4, 9} Lee H.J....Lee M.S. (2004)
7. G protein beta3 gene variant, vascular function, and insulin sensitivity in type 2 diabetes. (PubMed id 12511541)^{1, 4, 9} Fernandez-Real J.M....Ricart W. (2003)
8. Association between a polymorphism in the G protein beta3 subunit gene (GNB3) with arterial hypertension but not with myocardial infarction. (PubMed id 11230982)^{1, 4, 9} Hengstenberg C....Holmer S.R. (2001)
9. [Absence of an association between the C825T polymorphism of the G-protein beta 3 subunit and salt-sensitivity in essential arterial hypertension] (PubMed id 11816511)^{1, 4, 9} Gonzalez-Nunez D....Poch E. (2001)
10. Insulin-mediated venodilation is impaired in young, healthy carriers of the 825T allele of the G-protein beta3 subunit gene (GNB3). (PubMed id 15961981)^{1, 4, 9} Mitchell A....Schafers R.F. (2005)
11. Association of GNB3 gene with pulse pressure and clustering of risk factors for cardiovascular disease in Japanese. (PubMed id 15033462)^{1, 4, 9} Yamamoto M....Nakura J. (2004)
12. [Polymorphic markers of GNB3 (C825T), AGTR1 (A1166C) and ACE (A2350G and I/D) genes in patients with arterial hypertension combined with diabetes mellitus type 2] (PubMed id 15332573)^{1, 4, 9} Karpov R.S....Atroshenkov A.V. (2004)
13. Renin-angiotensin-aldosterone system and G-protein beta-3 subunit gene polymorphisms in salt-sensitive essential hypertension. (PubMed id 12624609)^{1, 4, 9} Pamies-Andreu E....Carneado de la Fuente J. (2003)
14. Age-dependent antidepressant pharmacogenomics: polymorphisms of the serotonin transporter and G protein beta3 subunit as predictors of response to fluoxetine and nortriptyline. (PubMed id 14604448)^{1, 4, 9} Joyce P.R....Kennedy M.A. (2003)
15. Effect of the C825T polymorphism of the G protein beta 3 subunit on the systolic blood pressure-lowering effect of clonidine in young, healthy male subjects. (PubMed id 12844135)^{1, 4, 9} Nurnberger J....Schafers R.F. (2003)
16. Associations of a human G protein beta3 subunit dimorphism with insulin resistance and carotid atherosclerosis. (PubMed id 12624279)^{1, 4, 9} Wascher T.C....Renner W. (2003)
17. Association analysis of a functional G protein beta3 subunit gene polymorphism (C825T) in mood disorders. (PubMed id 11586049)^{1, 4, 9} Lin C.N....Hong C.J. (2001)
18. Association between the GNB3 polymorphism and blood pressure in young Korean men. (PubMed id 16015130)^{1, 4, 9} Lee J....Kang H.S. (2005)
19. DNA polymorphisms in the tyrosine hydroxylase and GNB3 genes: association with unexpected death from acute myocardial infarction and increased heart weight. (PubMed id 16139102)^{1, 4, 9} Klintschar M....Kleiber M. (2005)
20. Association of C825T polymorphism of G protein beta3 subunit with the autonomic nervous system in young healthy Japanese individuals. (PubMed id 15831363)^{1, 4, 9} Matsunaga T....Yasuda K. (2005)
21. Venous response to nitroglycerin is enhanced in young, healthy carriers of the 825T allele of the G protein beta3 subunit gene (GNB3). (PubMed id 14586390)^{1, 4, 9} Mitchell A....Schafers R.F. (2003)
22. Role of the eNOS Glu298Asp variant on the GNB3825T allele dependent determination of alpha-adrenergic coronary constriction. (PubMed id 12724620)^{1, 4, 9} Naber C.K....Erbel R. (2003)
23. G-protein beta3 subunit and alpha-adducin polymorphisms and risk of subclinical and clinical stroke. (PubMed id 11283377)^{1, 4, 9} Morrison A.C....Boerwinkle E. (2001)
24. Association of a human G-protein beta3 subunit variant with hypertension. (PubMed id 9425898)^{1, 4, 9} Siffert W....Horsthemke B. (1998)
25. Response to fluoxetine and serotonin 1A receptor (C-1019G) polymorphism in Taiwan Chinese major depressive disorder. (PubMed id 16302021)^{1, 4, 9} Hong C.J....Tsai S.J. (2006)
26. Genetic diseases associated with heterotrimeric G pro teins. (PubMed id 16600389)^{1, 3, 9} Weinstein L.S....Liu J. (2006)
27. Clinical and genetic associations with hypertriglyceridemic waist in a Canadian aboriginal population. (PubMed id 16276364)^{1, 4, 9} Pollex R.L....Hegele R.A. (2006)
28. Lack of association between certain candidate gene polymorphisms and the metabolic syndrome. (PubMed id 15978856)^{1, 4, 9} Meirhaeghe A....Dallongeville J. (2005)
29. Association between hypertension and the alpha-adducin, beta1-adrenoreceptor, and G-protein beta3 subunit genes in the Japanese population; the Suita study. (PubMed id 15055253)^{1, 4, 9} Shioji K....Iwaii N. (2004)
30. G protein polymorphisms do not predict weight loss and improvement of hypertension in severely obese patients. (PubMed id 15531240)^{1, 4, 9} Potoczna N....Horber F.F. (2004)
31. Association study of adrenergic beta3 receptor (Trp64Arg) and G-protein beta3 subunit gene (C825T) polymorphisms and weight change during clozapine treatment. (PubMed id 15179018)^{1, 4, 9} Tsai S.J....Hong C.J. (2004)
32. The thiazide-sensitive Na(+)-Cl(-) cotransporter gene, C1784T, and adrenergic receptor-beta3 gene, T727C, may be gene polymorphisms susceptible to the antihypertensive effect of thiazide diuretics. (PubMed id 15824464)^{1, 4, 9} Matayoshi T....Kawano Y. (2004)
33. SSRIs antidepressant activity is influenced by G beta 3 variants. (PubMed id 12650956)^{1, 4, 9} Serretti A....Smeraldi E. (2003)
34. G-protein beta3-subunit gene 825T allele and hypertension: a longitudinal study in young grade I hypertensives. (PubMed id 14557282)^{1, 4, 9} Sartori M....Palatini P. (2003)
35. G-protein beta3 subunit gene C825T polymorphism is associated with arterial hypertension in Polish patients with type 2 diabetes mellitus. (PubMed id 12165748)^{1, 4, 9} Dzida G....Hanzlik J. (2002)
36. Pharmacogenetics of lithium prophylaxis in mood disorders: analysis of COMT, MAO-A, and Gbeta3 variants. (PubMed id 11992559)^{1, 4, 9} Serretti A....Smeraldi E. (2002)
37. G-protein beta-3-subunit and eNOS gene polymorphism in transplant recipients with long-term renal graft function. (PubMed id 12424427)^{1, 4, 9} Viklicky O....Szabo A.J. (2002)
38. Association between the G protein beta3 subunit 825t allele and radial artery hypertrophy. (PubMed id 12566975)^{1, 4, 9} Hanon O....Girerd X. (2002)
39. Association study of eight candidate genes with renin status in mild-to-moderate hypertension in patients of African ancestry. (PubMed id 11447495)^{1, 4, 9} Tiago A.D....Norton G.R. (2001)
40. G-protein beta(3) subunit gene (GNB3) 825T allele is associated with enhanced renal perfusion in early hypertension. (PubMed id 11244012)^{1, 4, 9} Zeltner R....Schmieder R.E. (2001)
41. The cationic region of Rhes mediates its interactions with specific Gbeta subunits. (PubMed id 19255495)^{1, 2} Hill C....Davey J. (2009)
42. Interactions between five candidate genes and antihypertensive drug therapy on blood pressure. (PubMed id 16314886)^{1, 4} Schelleman H....Klungel O.H. (2006)
43. Lack of association between human G-protein beta3 subunit variant and overweight in Japanese workers. (PubMed id 14742836)^{1, 4} Suwazono Y....Nogawa K. (2004)
44. Association of NQO1 polymorphism with spontaneous breast cancer in two independent populations. (PubMed id 15138483)^{1, 4} Menzel H.J....Kraft H.G. (2004)
45. G-protein beta 3 subunit 825 CC genotype is associated with unexplained (functional) dyspepsia. (PubMed id 15057736)^{1, 4} Holtmann G....Talley N.J. (2004)
46. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
47. G protein beta3 subunit 825T allele is associated with depression in young, healthy subjects. (PubMed id 12634518)^{1, 4} Exton M.S....Schedlowski M. (2003)
48. C825T polymorphism in the G protein beta3-subunit gene is associated with seasonal affective disorder. (PubMed id 14512207)^{1, 4} Willeit M....Bondy B. (2003)
49. [G protein beta 3 subunit C825T polymorphism and essential hypertension in Chinese] (PubMed id 12947562)^{1, 4} Wang H....Gou S. (2003)
50. Genetic risk factors for erectile dysfunction and genetic determinants of drug response--on the way to improve drug safety? (PubMed id 12825146)^{1, 4} Eisenhardt A. and Siffert W. (2003)
51. G protein beta 3 subunit 825T allele carriage and risk of coronary artery disease. (PubMed id 12618278)^{1, 4} von Beckerath N....Kastrati A. (2003)
52. Prediction of genetic risk for hypertension. (PubMed id 12654703)^{1, 4} Izawa H....Yokota M. (2003)
53. An epidemiological study of blood pressure and metabolic phenotypes in relation to the Gbeta3 C825T polymorphism. (PubMed id 12658019)^{1, 4} Brand E....Staessen J.A. (2003)
54. [Association of a polymorphic marker C825T of the beta(3) subunit of G-protein with myocardial hypertrophy in patients with hypertensive disease] (PubMed id 12891286)^{1, 4} Shliakhto E.V....Konradi A.O. (2003)
55. ADD1 460W allele associated with cardiovascular disease in hypertensive individuals. (PubMed id 12052841)^{1, 4} Morrison A.C....Boerwinkle E. (2002)
56. Association of the G protein beta3 subunit T allele with insulin resistance in essential hypertension. (PubMed id 12109775)^{1, 4} Poch E....de la Sierra A. (2002)
57. Analysis of several hundred genetic polymorphisms may improve assessment of the individual genetic burden for coronary artery disease. (PubMed id 12446192)^{1, 4} Ortlepp J.R....Hoffmann R. (2002)
58. Association study of C825T polymorphism of the G-protein b3 subunit gene with schizophrenia and mood disorders. (PubMed id 12075862)^{1, 4} Kunugi H....Nanko S. (2002)
59. [Polymorphism analysis of 825C/T of the G-protein beta 3 subunit in high risk population of hypertension in the northeast China] (PubMed id 11985260)^{1, 4} Dai S.P....Zhao Y.Y. (2002)
60. Multi-locus interactions predict risk for post-PTCA restenosis: an approach to the genetic analysis of common complex disease. (PubMed id 12082592)^{1, 4} Zee R.Y....Lindpainter K. (2002)
61. G protein beta3 subunit 825T genotype is not associated with differing outcome in pediatric renal transplant recipients. (PubMed id 12000471)^{1, 4} Hocher B....Filler G. (2002)
62. Molecular genetics of G proteins and atherosclerosis risk. (PubMed id 11770079)^{1, 3} Siffert W. (2001)
63. An association study of five genetic loci and left ventricular hypertrophy amongst Gulf Arabs. (PubMed id 11768721)^{1, 4} Obineche E.N....Bokhari A.M. (2001)
64. Analysis of 825C/T polymorphism of G proteinbeta3 subunit in obese/diabetic Japanese. (PubMed id 11520049)^{1, 4} Ohshiro Y....Nanjo K. (2001)
65. G protein beta3 subunit gene 825T allele is associated with increased left ventricular mass in young subjects with mild hypertension. (PubMed id 11775125)^{1, 4} Semplicini A....Palatini P. (2001)
66. Large-scale sequencing in human chromosome 12p13: experimental and computational gene structure determination. (PubMed id 9074930)^{1, 2} Ansari-Lari M.A....Gibbs R.A. (1997)
67. A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13. (PubMed id 8723724)^{1, 2} Ansari-Lari M.A....Gibbs R.A. (1996)
68. Molecular cloning of beta 3 subunit, a third form of the G protein beta-subunit polypeptide. (PubMed id 2107550)^{1, 2} Levine M.A.... Ahn T.G. (1990)
69. Identification and ethnic distribution of major haplotypes in the gene GNB3 encoding the G-protein beta3 subunit. (PubMed id 11927836)^{1, 9} Rosskopf D....Siffert W. (2002)
70. Homozygous 825T allele of the GNB3 protein influences the susceptibility of Japanese to dyspepsia. (PubMed id 17717746)^{1, 9} Tahara T....Nakano H. (2008)
71. G-protein beta3 subunit (GNB3) gene polymorphisms and cardiovascular disease: the Ludwigshafen Risk and Cardiovascular Health (LURIC) study. (PubMed id 16908025)^{1, 9} Renner W....Marz W. (2007)
72. GNB3 gene C825T and ACE gene I/D polymorphisms in essential hypertension in a Kazakh genetic isolate. (PubMed id 15042113)^{1, 9} Wang X....Wen H. (2004)
73. [Association of alpha-adducin gene and G-protein beta3-subuint gene with essential hypertension in Chinese] (PubMed id 17825147)^{1, 9} Huang X.H....Hui R.T. (2007)
74. Human G-protein beta3 subunit variant is associated with serum potassium and total cholesterol levels but not with blood pressure. (PubMed id 10701813)^{4, 9} Ishikawa K....Ogihara T. (2000)
75. A Preliminary Candidate Genotype-Intermediate Phenoty pe Study of Satiation and Gastric Motor Function in Obesity. (PubMed id 19876010)^{1, 9} Papathanasopoulos A....Zinsmeister A.R. (2009)
76. [Analysis of the GNB3 gene 825C/T polymorphism in non-obese and obese Chinese.] (PubMed id 19065529)^{1, 9} Wang X....Liu B. (2008)
77. Interaction between TPH1 and GNB3 genotypes and electroconvulsive therapy in major depression. (PubMed id 17066254)^{1, 9} Anttila S....Lehtimaki T. (2007)
78. C825T polymorphism in the human G protein beta 3 subunit gene and preeclampsia; a case control study. (PubMed id 15369653)^{1, 9} Jansen M.W....de Groot C.J. (2004)
79. The CC genotype of the C825T polymorphism of the G protein beta3 gene (GNB3) is associated with a high relapse rate in patients with chronic lymphocytic leukaemia. (PubMed id 14692527)^{1, 9} Nuckel H....Siffert W. (2003)
80. Identification and characterization of G beta 3s2, a novel splice variant of the G-protein beta 3 subunit. (PubMed id 12431187)^{1, 9} Rosskopf D....Siffert W. (2003)
81. Interaction of serotonin-related genes affects short- term antidepressant response in major depressive disorder. (PubMed id 19560507)^{1, 9} Lin E....Lu R.B. (2009)
82. Novel genetic variants in the alpha-adducin and guani ne nucleotide binding protein beta-polypeptide 3 genes and salt sensitivity of blood pressure. (PubMed id 19574959)^{1, 9} Kelly T.N....He J. (2009)
83. Effects of the C825T polymorphism of the GNB3 gene on body adiposity and blood pressure in fertile and menopausal women: a population-based study. (PubMed id 18192837)^{1, 9} Casiglia E....Pessina A.C. (2008)
84. Association of insulin sensitivity and glucose tolerance with the c.825C>T variant of the G protein beta-3 subunit gene. (PubMed id 18413224)^{1, 9} Kopf D....Lehnert H. (2008)
85. Association of antipsychotic induced weight gain and body mass index with GNB3 gene: A meta-analysis. (PubMed id 18793692)^{1, 9} Souza R.P....Kennedy J.L. (2008)
86. Interaction of G-protein beta(3) Subunit and Nitric Oxide Synthase Gene Polymorphisms on Carotid Artery Intima-media Thickness in Young Adults: The Bogalusa Heart Study. (PubMed id 18551105)^{1, 9} Bhuiyan A.R....Berenson G.S. (2008)
87. [Association of GNB3 gene C825T polymorphism with coronary heart disease] (PubMed id 17958314)^{1, 9} Nikitin A.G....Debabov V.G. (2007)
88. The GNB3 C825T polymorphism affects response to HCV therapy with pegylated interferon in HCV/HIV co-infected but not in HCV mono-infected patients. (PubMed id 17559964)^{1, 9} Ahlenstiel G....Nattermann J. (2007)
89. [C825T polymorphism of the GNB3 gene codifying the G-protein beta3-subunit and cardiovascular risk] (PubMed id 15678704)^{1, 9} Sartori M....Semplicini A. (2004)
90. The G-protein beta3 subunit 825 TT genotype is associ ated with epigastric pain syndrome-like dyspepsia. (PubMed id 20102604)^{1, 9} Oshima T....Miwa H. (2010)
91. Weight loss and body fat reduction under sibutramine therapy in obesity with the C825T polymorphism in the GNB3 gene. (PubMed id 19687782)^{1, 9} Hsiao D.J....Lin E. (2009)
92. The C825T polymorphism in the G-protein beta 3 subunit gene in Chinese patients with preeclampsia. (PubMed id 19437226)^{1, 9} He G....Bai H. (2009)
93. Lack of an association of GNB3 C825T polymorphism and blood pressure in patients with rheumatoid arthritis. (PubMed id 19811352)^{1, 9} Panoulas V.F....Kitas G.D. (2009)
94. Salt consumption-dependent association of the GNB3 gene polymorphism with type 2 DM. (PubMed id 18656447)^{1, 9} Daimon M....Kato T. (2008)
95. Gene-environment interaction and the GNB3 gene in the Atherosclerosis Risk in Communities study. (PubMed id 17299380)^{1, 9} Grove M.L....Bray M.S. (2007)
96. Association between 5-HT2A, TPH1 and GNB3 genotypes and response to typical neuroleptics: a serotonergic approach. (PubMed id 17521439)^{1, 9} Anttila S....Leinonen E. (2007)
97. Association of the C825T polymorphism of the G-protein beta3 subunit gene with hypertension, obesity, hyperlipidemia, insulin resistance, diabetes, diabetic complications, and diabetic therapies among Japanese. (PubMed id 17161225)^{1, 9} Hayakawa T....Kaneko S. (2007)
98. Allelic variants interaction of CLOCK gene and G-protein beta3 subunit gene with diurnal preference. (PubMed id 17701674)^{1, 9} Lee H.J....Kim L. (2007)
99. No evidence for an association between G protein beta3 subunit gene C825T polymorphism and tardive dyskinesia in schizophrenia. (PubMed id 17726725)^{1, 9} Lee H.J....Lee M.S. (2007)
100. Combination of the C1429T polymorphism in the G-protein beta-3 subunit gene and the A1330V polymorphism in the low-density lipoprotein receptor-related protein 5 gene is a risk factor for hypercholesterolaemia. (PubMed id 17972053)^{1, 9} Suwazono Y....Nogawa K. (2007)
101. G-protein beta 3 subunit polymorphism C1429T and low-density lipoprotein receptor-related protein 5 polymorphism A1330V are risk factors for hypercholesterolemia in Japanese males--a prospective study over 5 years. (PubMed id 16713434)^{1, 9} Suwazono Y....Nogawa K. (2006)
102. Hydrochlorothiazide efficacy and polymorphisms in ACE, ADD1 and GNB3 in healthy, male volunteers. (PubMed id 16450155)^{1, 9} Vormfelde S.V....Brockmoller J. (2006)
103. Different genotype distribution of the GNB3 C825T polymorphism of the G protein beta3 subunit in adenomas and differentiated thyroid carcinomas of follicular cell origin. (PubMed id 16178055)^{1, 9} Sheu S.Y....Schmid K.W. (2005)
104. C825T polymorphism in the human G protein beta3 subunit gene is associated with long-term clozapine treatment-induced body weight change in the Chinese population. (PubMed id 16141801)^{1, 9} Wang Y.C....Liou Y.J. (2005)
105. C825T polymorphism of the G protein beta3 subunit is associated with obesity but not with insulin sensitivity. (PubMed id 15090636)^{1, 9} Stefan N....Fritsche A. (2004)
106. Glucose and lipid metabolism in young lean normotensive males with the G protein beta3 825T-allele. (PubMed id 12730030)^{1, 9} Saller B....Rosskopf D. (2003)
107. G-protein beta3 subunit gene splice variant in obesity and overweight. (PubMed id 11439289)^{1, 9} Benjafield A.V....Morris B.J. (2001)
108. No evidence for involvement of alleles of the 825-C/T polymorphism of the G-protein subunit beta 3 in body weight regulation. (PubMed id 11748488)^{1, 9} Hinney A....Hebebrand J. (2001)
109. Interaction of the ACE D allele and the GNB3 825T allele in myocardial infarction. (PubMed id 11116112)^{1, 9} Naber C.K....Siffert W. (2000)
110. 825T allele of the G-protein beta3 subunit gene (GNB3) is associated with impaired left ventricular diastolic filling in essential hypertension. (PubMed id 10526907)^{4, 9} Jacobi J....Schmieder R.E. (1999)
111. Haplotypes of the adrenergic system predict the blood pressure response to beta-blockers in women with essential hypertension. (PubMed id 20235788)^{1, 9} Filigheddu F....Glorioso N. (2010)
112. Effect of the common -866G/A polymorphism of the unco upling protein 2 gene on weight loss and body composition under sibutramine the rapy in an obese Taiwanese population. (PubMed id 20359253)^{1, 9} Hsiao T.J....Lin E. (2010)
113. Genetic insight into syncopal tilted population with severe clinical presentation. (PubMed id 19243996)^{1, 9} Lelonek M....Goch J.H. (2009)
114. Intensity of opiate withdrawal in relation to the 825C>T polymorphism of the G-protein beta 3 subunit gene. (PubMed id 19303909)^{1, 9} Lieb B....Scherbaum N. (2009)
115. Common variants in the G protein beta3 subunit gene a nd thyroid disorders in a formerly iodine-deficient population. (PubMed id 19772422)^{1, 9} VAPlzke H....Rosskopf D. (2009)
116. [Association of genetic factors with clinical peculiarities of hypertensive disease in patients with burdened familial anamnesis] (PubMed id 19254215)^{1, 9} (2009)
117. Antidepressant response and intolerance to SSRI is not influenced by G-protein beta3 subunit gene C825T polymorphism in Japanese major depressive patients. (PubMed id 18325652)^{1, 9} Kato M....Serretti A. (2008)
118. Study on the interrelationship between 5-HTTLPR/G-protein beta3 subunit (C825T) polymorphisms and depressive disorder. (PubMed id 17621167)^{1, 9} Cao M.Q....Xia D.S. (2007)
119. Relationship between G-protein beta-3 subunit C825T polymorphism and mirtazapine responses in Korean patients with major depression. (PubMed id 17943025)^{1, 9} Kang R.H....Lee M.S. (2007)
120. Impact of variation in ADRB2, ADRB3, and GNB3 genes on body mass index and waist circumference in a Brazilian population. (PubMed id 16493638)^{1, 9} Mattevi V.S....Hutz M.H. (2006)
121. The angiotensin II receptor antagonist valsartan inhibits endothelin 1-induced vasoconstriction in the skin microcirculation in humans in vivo: influence of the G-protein beta3 subunit (GNB3) C825T polymorphism. (PubMed id 16513451)^{1, 9} Mitchell A....Wenzel R.R. (2006)
122. G-protein beta3 subunit gene variant is unlikely to have a significant influence on serum uric acid level in Japanese workers. (PubMed id 16707857)^{1, 9} Suwazono Y....Nogawa K. (2006)
123. Better identification of patients who benefit from implantable cardioverter defibrillators by genotyping the G protein beta3 subunit (GNB3) C825T polymorphism. (PubMed id 16783490)^{1, 9} Wieneke H....Siffert W. (2006)
124. Hypertension, obesity and GNB 3 gene variants. (PubMed id 16487269)^{1, 9} Danoviz M.E....Krieger J.E. (2006)
125. GNB3 C825T and ACE I/D polymorphisms on the sodium-proton exchanger and the prevalence of essential hypertension in males. (PubMed id 16314202)^{1, 9} Kedzierska K....Chlubek D. (2006)
126. GNB3 C825T polymorphism and response to interferon-alfa/ribavirin treatment in patients with hepatitis C virus genotype 1 (HCV-1) infection. (PubMed id 16019105)^{1, 9} Sarrazin C....Siffert W. (2005)
127. Suggestive association between the C825T polymorphism of the G-protein beta3 subunit gene (GNB3) and clinical improvement with antipsychotics in schizophrenia. (PubMed id 16139171)^{1, 9} Muller D.J....Kennedy J.L. (2005)
128. [Activity of the sodium-proton exchanger and polymorphism of G-protein beta-3 subunit in patients with essential hypertension] (PubMed id 16871746)^{1, 9} Kedzierska K. (2004)
129. Lack of association of human G-protein beta 3 subunit variant with hypertension in Japanese workers. (PubMed id 15076154)^{1, 9} Suwazono Y....Nogawa K. (2004)
130. Obesity reveals an association between blood pressure and the G-protein beta3-subunit gene: a study of female dizygotic twins. (PubMed id 15226674)^{1, 9} Dong Y....Snieder H. (2004)
131. Polymorphism in genes involved in adrenergic signaling associated with Alzheimer's. (PubMed id 15212839)^{1, 9} Bullido M.J....Valdivieso F. (2004)
132. G-Protein beta(3) subunit C825T variant, nephropathy and hypertension in patients with type 2 (Non-insulin-dependent) diabetes mellitus. (PubMed id 10970984)^{4, 9} Zychma M.J....Grzeszczak W. (2000)
133. Frequencies of genetic polymorphisms related to tript ans metabolism in chronic migraine. (PubMed id 20213484)^{1, 9} Gentile G....Martelletti P. (2010)
134. [Myocardial hypertrophy in patients with hypertensive disease: the role of genetic polymorphism of beta-adrenoreactive structures] (PubMed id 20144152)^{1, 9} (2010)
135. The environmental and genetic evidence for the association of hyperlipidemia and hypertension. (PubMed id 19155782)^{1, 9} Ruixing Y....Shangling P. (2009)
136. The contribution of six polymorphisms to cardiovascular risk in a Dutch high-risk primary care population: the HIPPOCRATES project. (PubMed id 19242491)^{1, 9} Plat A.W....Kroon A.A. (2009)
137. Hunger and Mood during Extended Fasting Are Dependent on the GNB3 C825T Polymorphism. (PubMed id 19420911)^{1, 9} Michalsen A....Dobos G.J. (2009)
138. Association of a polymorphism of the apolipoprotein E gene with chronic kidney disease in Japanese individuals with metabolic syndrome. (PubMed id 19056482)^{1, 9} Yoshida T....Yamada Y. (2009)
139. Hypertension genes and retinal vascular calibre: the Cardiovascular Health Study. (PubMed id 19148102)^{1, 9} Sun C....Wong T.Y. (2009)
140. Association of GNB3 C825T polymorphism with peak oxygen consumption. (PubMed id 19301222)^{1, 9} Faruque M.U....Campbell A.L. (2009)
141. The association between arterial stiffness and the angiotensin II type 1 receptor (A1166C) polymorphism is influenced by the use of cardiovascular medication. (PubMed id 19145770)^{1, 9} Plat A.W....Kroon A.A. (2009)
142. The influence of six cardiovascular polymorphisms on a first event of ischemic heart disease is modified by sex and age. (PubMed id 19779330)^{1, 9} Plat A.W....Kroon A.A. (2009)
143. G-protein gene 825C>T polymorphism is associated with response to clozapine in Brazilian schizophrenics. (PubMed id 18855531)^{1, 9} Kohlrausch F.B....Hutz M.H. (2008)
144. Genetic profile of ischemic cerebrovascular disease and carotid stenosis. (PubMed id 18325076)^{1, 9} Kostulas K....Hillert J. (2008)
145. Association of FTO with obesity-related traits in the Cebu Longitudinal Health and Nutrition Survey (CLHNS) Cohort. (PubMed id 18426866)^{1, 9} Marvelle A.F....Mohlke K.L. (2008)
146. [Study on the association of predisposing genes with essential hypertension among Kazakhs ethnic group in Xinjiang] (PubMed id 19103106)^{1, 9} Chen X.D....Jin L. (2008)
147. Multiple genetic factors in olanzapine-induced weight gain in schizophrenia patients: a cohort study. (PubMed id 19193342)^{1, 9} Ujike H....Kuroda S. (2008)
148. Candidate genotypes associated with functional dyspepsia. (PubMed id 18331431)^{1, 9} van Lelyveld N....Samsom M. (2008)
149. Interaction between GNB3 C825T and ACE I/D polymorphisms in essential hypertension in Koreans. (PubMed id 17066084)^{1, 9} Bae Y....Yoon S.K. (2007)
150. The GNB3 C825T polymorphism and essential hypertension: a meta-analysis of 34 studies including 14,094 cases and 17,760 controls. (PubMed id 17278960)^{1, 9} Bagos P.G....Hamodrakas S.J. (2007)
151. Alteration of gastric functions and candidate genes associated with weight reduction in response to sibutramine. (PubMed id 17544870)^{1, 9} Vazquez Roque M.I....Zinsmeister A.R. (2007)
152. The C allele of the GNB3 C825T polymorphism of the G protein beta3-subunit is associated with an increased risk for the development of oncocytic thyroid tumours. (PubMed id 17136758)^{1, 9} Sheu S.Y....Schmid K.W. (2007)
153. Diuretic-gene interaction and the risk of myocardial infarction and stroke. (PubMed id 17189961)^{1, 9} Schelleman H....Stricker B.H. (2007)
154. Serotonin 2A -1438 G/A and G-protein Beta3 subunit C825T polymorphisms in patients with depression and SSRI-associated sexual side-effects. (PubMed id 16710319)^{1, 9} Bishop J.R....Clayton A.H. (2006)
155. Lack of association between the C825T polymorphism in G-protein beta-3 subunit and arterial blood pressure levels in cardiovascular disease free individuals: the ATTICA epidemiological study. (PubMed id 16424860)^{1, 9} Pitsavos C....Stefanadis C. (2006)
156. Risks of human limb deficiency anomalies associated with 29 SNPs of genes involved in homocysteine metabolism, coagulation, cell-cell interactions, inflammatory response, and blood pressure regulation. (PubMed id 17036337)^{1, 9} Carmichael S.L....Lammer E.J. (2006)
157. Platelet hyperreactivity generalizes to multiple forms of stimulation. (PubMed id 16961612)^{1, 9} Yee D.L....Bray P.F. (2006)
158. Polymorphisms in four candidate genes in young patients with essential hypertension. (PubMed id 16497648)^{1, 9} Marcun Varda N....Gregoric A. (2006)
159. [Association analysis of the essential hypertension susceptibility genes in adolescents: Kangwha study] (PubMed id 16615274)^{1, 9} Suh I....Kang D.R. (2006)
160. Update on G-protein polymorphisms in hypertension. (PubMed id 16600156)^{1, 9} Zhu H....Dong Y. (2006)
161. G protein beta 3 subunit gene variants and essential hypertension in the northern Chinese Han population. (PubMed id 15996174)^{1, 9} Li B....Chen R. (2005)
162. G-protein beta-3 subunit gene 825C>T dimorphism is associated with left ventricular hypertrophy but not essential hypertension. (PubMed id 15614196)^{1, 9} Mahmood M.S....Frossard P.M. (2005)
163. G-protein beta-3 subunit gene C825 T polymorphism: influence on plasma sodium and potassium concentrations in essential hypertensive patients. (PubMed id 16002097)^{1, 9} Martin D.N....Carneado de la Fuente J. (2005)
164. C825T polymorphism of the G-protein beta3 subunit gene and atrial fibrillation: association of the TT genotype with a reduced risk for atrial fibrillation. (PubMed id 15389246)^{1, 9} Schreieck J....Schmitt C. (2004)
165. G protein beta3 subunit C825T polymorphism in primary IgA nephropathy. (PubMed id 15200440)^{1, 9} Thibaudin L....Berthoux F. (2004)
166. Characterization of the splice variant Gbeta3v of the human G-protein Gbeta3 subunit. (PubMed id 12697327)^{1, 9} Rosskopf D....Siffert W. (2003)
167. Lack of association of G-protein subunit gene C825T polymorphism with left ventricular hypertrophy in essential hypertension. (PubMed id 12011775)^{1, 9} Shlyakhto E.V....Konrady A.O. (2002)
168. Polymorphisms of genes encoding components of the sympathetic nervous system but not the renin-angiotensin system as risk factors for orthostatic hypotension. (PubMed id 11910300)^{1, 9} Tabara Y....Miki T. (2002)
169. Combined action of the ACE D- and the G-protein beta3 T-allele in major depression: a possible link to cardiovascular disease? (PubMed id 12476328)^{1, 9} Bondy B....Engel R.R. (2002)
170. Effects of the G-protein beta3 subunit 825T allele on adipogenesis and lipolysis in cultured human preadipocytes and adipocytes. (PubMed id 12384823)^{1, 9} Hauner H....Siffert W. (2002)
171. Association analysis of G-protein beta 3 subunit gene with altered Ca(2+) homeostasis in bipolar disorder. (PubMed id 11317211)^{4, 9} Corson T.W....Warsh J.J. (2001)
172. G-protein beta3 subunit C825T polymorphism: no association with risk for hypertension and obesity. (PubMed id 11725157)^{4, 9} Snapir A....Scheinin M. (2001)
173. Evidence for an association between a G-protein beta3-gene variant with depression and response to antidepressant treatment. (PubMed id 10884039)^{4, 9} Zill P....Bondy B. (2000)
174. Genetic variants, endothelial function, and risk of preeclampsia among American Indians. (PubMed id 21174581)¹ Best L.G....Anderson C.M. (2012)
175. Association between the G-protein b3 subunit C825T pol ymorphism with essential hypertension: a meta-analysis in Han Chinese population . (PubMed id 22714918)¹ Lu J....Wang W. (2012)
176. A two-stage matched case-control study on multiple hyp ertensive candidate genes in Han Chinese. (PubMed id 22534794)¹ Kuo T.Y....Pan W.H. (2012)
177. Influence of 825 C>T polymorphism of G protein b3 s ubunit gene (GNB3) on hemodynamic response during dobutamine stress echocardiogr aphy. (PubMed id 22580528)¹ Banas A....Drozdzik M. (2012)
178. The C825T GNB3 polymorphism, independent of blood pres sure, predicts cerebrovascular risk at a population level. (PubMed id 22258330)¹ Casiglia E....Palatini P. (2012)
179. Genome-wide association study identifies three common variants associated with serologic response to vitamin E supplementation in men. (PubMed id 22437554)¹ Major J.M....Albanes D. (2012)
180. The role of G protein gene GNB3 C825T polymorphism in HIV-1 acquisition, progression and immune activation. (PubMed id 22214232)¹ Juno J....Fowke K.R. (2012)
181. G Protein b3 subunit gene C825T polymorphism and its a ssociation with the presence and clinicopathological characteristics of prostate cancer. (PubMed id 22608746)¹ Safarinejad M.R....Safarinejad S. (2012)
182. The GNB3 C825T polymorphism influences platelet aggreg ation in human whole blood. (PubMed id 22082654)¹ Dusse F....Peters J. (2012)
183. Association between genetic variants of the ADD1 and G NB3 genes and blood pressure response to the cold pressor test in a Chinese Han population: the GenSalt Study. (PubMed id 22476228)¹ Wang L....Gu D. (2012)
184. [Genotype of the GNB3 C825T polymorphism, A risk fact or for the development and course of prostate cancer?]. (PubMed id 21735268)¹ Eisenhardt A....RA1bben H. (2011)
185. C825T polymorphism of the G-protein I^3 subunit and it s association with essential hypertension in Uzbek males. (PubMed id 21532295)¹ Khamidullaeva G.A....Abdullaeva G.J. (2011)
186. Is there an interaction between BDKRB2 -9/+9 and GNB3 C825T polymorphisms and elite athletic performance? (PubMed id 21210858)¹ Eynon N....Eliakim A. (2011)
187. Association of I+-adducin and G-protein I^3 genetic pol ymorphisms with hypertension: a meta-analysis of Chinese populations. (PubMed id 21364877)¹ Niu W. and Qi Y. (2011)
188. [A protective effect of GLY272SER polymorphism of GNB 3 gene in development of essential hypertension and its relations with environm ental hypertension risk factors]. (PubMed id 21675276)¹ Polonikov A.V....Tevs D.S. (2011)
189. GNB3 C825T Polymorphism and elite athletic status: A replication study with two ethnic groups. (PubMed id 21110287)¹ Ruiz J.R....Lucia A. (2011)
190. Serotonin transporter and G protein beta 3 subunit ge ne polymorphisms in Greeks with irritable bowel syndrome. (PubMed id 21559741)¹ Markoutsaki T....Karamanolis D.G. (2011)
191. G-protein b3 subunit 825CC genotype is associated with postprandial distress syndrome with impaired gastric emptying and with the feel ing of hunger in Japanese. (PubMed id 21902766)¹ Shimpuku M....Sakamoto C. (2011)
192. Clinically silent adrenal adenomas - their relation to the metabolic syndrome and to GNB3 C825T gene polymorphism. (PubMed id 21979884)¹ Lazurova I....Pundova L. (2011)
193. The GNB3 C825T polymorphism as a pharmacogenetic mark er in the treatment of hypertension, obesity, and depression. (PubMed id 21709600)¹ Klenke S....Siffert W. (2011)
194. The role of G protein I^3 subunit polymorphisms C825T, C1429T, and G5177A in Turkish subjects with essential hypertension. (PubMed id 21473734)¹ Cabadak H....Kan B. (2011)
195. Effects of C825T polymorphism of the GNB3 gene on ava ilability of dopamine transporter in healthy volunteers--a SPECT study. (PubMed id 21371559)¹ Chen P.S....Chou Y.H. (2011)
196. Reduced prevalence of the C825T polymorphism of the G- protein beta subunit gene in women with breast cancer. (PubMed id 22034052)¹ Paleari R.G....Sarian L.O. (2011)
197. Full-length transcriptome analysis of human retina-derived cell lines ARPE-19 and Y79 using the vector-capping method. (PubMed id 21697133)¹ Oshikawa M.... Kato S. (2011)
198. Lack of association between genetic polymorphisms aff ecting sympathetic activity and tilt-induced vasovagal syncope. (PubMed id 20129829)¹ Sorrentino S....Favale S. (2010)
199. Variation in GNB3 predicts response and adverse react ions to antidepressants. (PubMed id 20826553)¹ Keers R....Gennarelli M. (2010)
200. Genetic associations of brain structural networks in schizophrenia: a preliminary study. (PubMed id 20691427)¹ Jagannathan K....Pearlson G.D. (2010)
201. Genetic associations with mountain sickness in Han an d Tibetan residents at the Qinghai-Tibetan Plateau. (PubMed id 20570668)¹ Buroker N.E....Chen S.H. (2010)
202. Genetic polymorphisms related to efficacy and overuse of triptans in chronic migraine. (PubMed id 20652353)¹ Gentile G....Martelletti P. (2010)
203. The serotonin transporter gene polymorphism STin2 VNT R confers an increased risk of inconsistent response to triptans in migraine pa tients. (PubMed id 20488209)¹ Terrazzino S....Genazzani A.A. (2010)
204. I^-blocker therapy and heart rate control during exerc ise testing in the general population: role of a common G-protein I^-3 subunit v ariant. (PubMed id 20860462)¹ DAPrr M....Rosskopf D. (2010)
205. Can we predict top-level sports performance in power vs endurance events? A genetic approach. (PubMed id 20459474)¹ Buxens A....Lucia A. (2010)
206. Association between common variation in genes encodin g sweet taste signaling components and human sucrose perception. (PubMed id 20660057)¹ Fushan A.A....Drayna D. (2010)
207. Dengue hemorrhagic fever is associated with polymorph isms in JAK1. (PubMed id 20588308)¹ Silva L.K....Teixeira M.G. (2010)
208. [Association between the polymorphism of GNB3C825T ge ne and vasovagal syncope in children]. (PubMed id 21215181)¹ Huang Y.J....Huang M. (2010)
209. Physiogenomic analysis of statin-treated patients: do main-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol? (PubMed id 20602615)¹ RuaA+o G....Wu A.H. (2010)
210. The G-protein I^3 polymorphism is associated with diff use type gastric cancer in Japanese. (PubMed id 21198262)¹ Shibata T....Hirata I. (2010)
211. Genetic association study of the GNB3 C825T, the ACE I/D and the eNOS G894T polymorphisms and the risk to develop erectile dysfuncti on in a German ED population. (PubMed id 20629643)¹ Eisenhardt A....Sperling H. (2010)
212. G-Protein beta3 subunit Polymorphism and Bleeding in the Orbofiban in Patients with Unstable Coronary Syndromes-Thrombolysis In Myoc ardial Infarction (OPUS-TIMI) 16 Trial. (PubMed id 20096003)¹ Maree A.O....Fitzgerald D.J. (2010)
213. C825T polymorphism of the GNB3 gene on valproate-rela ted metabolic abnormalities in bipolar disorder patients. (PubMed id 20814328)¹ Chang H.H....Chen P.S. (2010)
214. Genetic polymorphisms of the adrenergic system and im plantable cardioverter-defibrillator therapies in patients with heart failure. (PubMed id 20185488)¹ Chemello D....Clausell N. (2010)
215. Analysis of common germline polymorphisms as prognost ic factors in patients with lymph node-positive breast cancer. (PubMed id 20204402)¹ Knechtel G....Langsenlehner U. (2010)
216. Impact of genomic polymorphism on arterial hypertensi on after aortic coarctation repair. (PubMed id 20537417)¹ Hager A....Hess J. (2010)
217. G protein beta3 subunit, interleukin-10, and tumor ne crosis factor-alpha gene polymorphisms in Koreans with irritable bowel syndrome . (PubMed id 20337945)¹ Lee H.J....Jin C.J. (2010)
218. The IFNG (IFN-gamma) genotype predicts cytogenetic an d molecular response to imatinib therapy in chronic myeloid leukemia. (PubMed id 20959405)¹ Kim D.H....Lipton J.H. (2010)
219. The G protein I^3 subunit C825T polymorphism is associ ated with microalbuminuria in hypertensive women and cardiovascular disease in hypertensive men. (PubMed id 20577224)¹ Romundstad S....Holmen J. (2010)
220. Associations of markers in 11 obesity candidate genes with maximal weight loss and weight regain in the SOS bariatric surgery cases. (PubMed id 20733583)¹ Sarzynski M.A....Carlsson L.M. (2010)
221. Association of the GNB3 825T-allele with better survi val in patients with glioblastoma multiforme. (PubMed id 20145952)¹ El Hindy N....Sandalcioglu I.E. (2010)
222. Pharmacogenetic association of hypertension candidate genes with fasting glucose in the GenHAT Study. (PubMed id 20577119)¹ Irvin M.R....Arnett D.K. (2010)
223. A large-scale candidate gene association study of age at menarche and age at natural menopause. (PubMed id 20734064)¹ He C....Hunter D.J. (2010)
224. Association of Single-Nucleotide Polymorphisms From 1 7 Candidate Genes With Baseline Symptom-Limited Exercise Test Duration and Decr ease in Duration Over 20 Years: The Coronary Artery Risk Development in Young A dults (CARDIA) Fitness Study. (PubMed id 20952631)¹ Sarzynski M.A....Bouchard C. (2010)
225. Association of the G-protein and I+2-adrenergic recept or gene and plasma norepinephrine level with clonidine improvement of the effec ts of diuretics in patients with cirrhosis with refractory ascites: a randomise d clinical trial. (PubMed id 20833658)¹ Yang Y.Y....Lee S.D. (2010)
226. The genetics of loop diuretic effects. (PubMed id 20877298)¹ Vormfelde S.V. and BrockmAPller J. (2010)
227. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)¹ Bailey S.D....Anand S. (2010)
228. Independent predictive roles of eotaxin Ala23Thr, par aoxonase 2 Ser311Cys and beta-adrenergic receptor Trp64Arg polymorphisms on car diac disease in Type 2 Diabetes--an 8-year prospective cohort analysis of 1297 patients. (PubMed id 20536507)¹ Wang Y....Chan J.C. (2010)
229. Identification of type 2 diabetes-associated combinat ion of SNPs using support vector machine. (PubMed id 20416077)¹ Ban H.J....Park K.J. (2010)
230. Beta2-adrenoceptor gene variant Arg16Gly is associate d with idiopathic ventricular outflow-tract tachycardia. (PubMed id 21034538)¹ Ran Y.Q....Pu J.L. (2010)
231. Prognostic assessment of three single-nucleotide poly morphisms (GNB3 825C>T, BCL2-938C>A, MCL1-386C>G) in extrahepatic chol angiocarcinoma. (PubMed id 19968497)¹ Fingas C.D....Canbay A. (2010)
232. Polymorphisms in the GNB3 and ADD1 genes and blood pressure in a Chinese population. (PubMed id 20473689)¹ Chen S....Gu D. (2010)
233. The prevalence of Gly972Arg and C825T polymorphisms i n Slovak women with polycystic ovary syndrome and their relation to the metabol ic syndrome. (PubMed id 20170352)¹ DraveckA! I....HabalovA! V. (2010)
234. Identification of fetal and maternal single nucleotid e polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes. (PubMed id 20452482)¹ Romero R....Menon R. (2010)
235. A genetic association study of maternal and fetal can didate genes that predispose to preterm prelabor rupture of membranes (PROM). (PubMed id 20673868)¹ Romero R....Menon R. (2010)
236. SNP-by-fitness and SNP-by-BMI interactions from seven candidate genes and incident hypertension after 20 years of follow-up: the CAR DIA Fitness Study. (PubMed id 20944660)¹ Sarzynski M.A....Bouchard C. (2010)
237. Association Between the G Protein beta3 Subunit C825T Polymorphism and the Occurrence of Cardiovascular Disease in Hypertensives: Th e Nord-TrA,ndelag Health Study (HUNT). (PubMed id 20539277)¹ Holmen O.L....Melien O. (2010)
238. Poor replication of candidate genes for major depress ive disorder using genome-wide association data. (PubMed id 20351714)¹ Bosker F.J....Nolen W.A. (2010)
239. A candidate gene study of obstructive sleep apnea in European Americans and African Americans. (PubMed id 20538960)¹ Larkin E.K....Redline S. (2010)
240. GNB3 C825T polymorphism and elevated blood pressure. (PubMed id 19885780)¹ Lee J.Y....Kang H.S. (2009)
241. Sex-specific effect of the alpha-adducin (G460W) and AGTR1 (A1166C) polymorphism on carotid intima-media thickness. (PubMed id 19620885)¹ Plat A.W....Kroon A.A. (2009)
242. Severe obesity is associated with novel single nucleo tide polymorphisms of the ESR1 and PPARgamma locus in Han Chinese. (PubMed id 19491387)¹ Chen H.H....Pan W.H. (2009)
243. Integrative predictive model of coronary artery calci fication in atherosclerosis. (PubMed id 19948975)¹ McGeachie M....Ramoni M.F. (2009)
244. Pharmacogenetics of low dose clonidine in irritable bowel syndrome. (PubMed id 19309415)¹ Camilleri M....Zinsmeister A.R. (2009)
245. Association of genetic variants with chronic kidney d isease in individuals with different lipid profiles. (PubMed id 19578796)¹ Yoshida T....Yamada Y. (2009)
246. Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach. (PubMed id 19263529)¹ Zee R.Y....Glynn R.J. (2009)
247. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)¹ Talmud P.J.... . (2009)
248. Fulfilling the promise of personalized medicine? Syst ematic review and field synopsis of pharmacogenetic studies. (PubMed id 19956635)¹ Holmes M.V....Casas J.P. (2009)
249. Role of molecular chaperones in G protein beta5/regul ator of G protein signaling dimer assembly and G protein betagamma dimer specif icity. (PubMed id 19376773)¹ Howlett A.C....Willardson B.M. (2009)
250. Genetic variation in female BMI increases with number of children born but failure to replicate association between GNbeta3 variants and increased BMI in parous females. (PubMed id 19456220)¹ Cornes B.K....Martin N.G. (2009)
251. Gastroesophageal reflux disease is associated with the C825T polymorphism in the G-protein beta3 subunit gene (GNB3). (PubMed id 19174793)¹ de Vries D.R....Samsom M. (2009)
252. Case-control association study of 65 candidate genes revealed a possible association of a SNP of HTR5A to be a factor susceptible to bipolar disease in Bulgarian population. (PubMed id 19328558)¹ Yosifova A....Nakamura Y. (2009)
253. The guanine nucleotide binding protein beta polypeptide 3 gene C825T polymorphism is associated with elite endurance athletes. (PubMed id 19139061)¹ Eynon N....Duarte J.A. (2009)
254. Variation in Renin-Angiotensin system and salt-sensitivity genes and the risk of diabetes mellitus associated with the use of thiazide diuretics. (PubMed id 19247266)¹ Bozkurt O....Klungel O.H. (2009)
255. Genetic factors are relevant and independent determin ants of antihypertensive drug effects in a multiracial population. (PubMed id 19779464)¹ van Rijn-Bikker P.C....Koopmans R.P. (2009)
256. Phenotype-genotype interactions on renal function in type 2 diabetes: an analysis using structural equation modelling. (PubMed id 19479237)¹ Song X.Y....Chan J.C. (2009)
257. A splice variant of GNB3 and peripheral polyneuropath y in type 1 diabetes. (PubMed id 19597293)¹ Chistiakov D.A....Nosikov V.V. (2009)
258. A candidate gene association study of 77 polymorphism s in migraine. (PubMed id 19559392)¹ SchA1rks M....Zee R.Y. (2009)
259. A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients. (PubMed id 19131662)¹ Wang X....Cook N.R. (2009)
260. Genetic variants in the candidate genes of the apoptosis pathway and susceptibility to chronic myeloid leukemia. (PubMed id 19141860)¹ Kim D.H....Lipton J.H. (2009)
261. The genomic basis of cerebral palsy: a HuGE systematic literature review. (PubMed id 19238444)¹ O'Callaghan M.E....Dekker G. (2009)
262. Gbeta3 forms distinct dimers with specific Ggamma subunits and preferentially activates the beta3 isoform of phospholipase C. (PubMed id 19168127)¹ Poon L.S....Wong Y.H. (2009)
263. G protein beta3 subunit gene polymorphism in Turkish hypertensives. (PubMed id 18849222)¹ Alioglu E....Berdeli A. (2008)
264. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)¹ Barbe L....Andersson-Svahn H. (2008)
265. New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background. (PubMed id 18513389)¹ Penco S....Grossi E. (2008)
266. Estimation of single-nucleotide polymorphism allele frequency by alternately binding probe competitive polymerase chain reaction. (PubMed id 18215653)¹ Noda N....Sekiguchi Y. (2008)
267. A controlled pharmacogenetic trial of sibutramine on weight loss and body composition in obese or overweight adults. (PubMed id 18725220)¹ Grudell A.B....Zinsmeister A.R. (2008)
268. Genetic variants in the alpha2C-adrenoceptor and G-protein contribute to ethnic differences in cardiovascular stress responses. (PubMed id 18698227)¹ Kurnik D....Stein C.M. (2008)
269. Candidate Genes and Sensory Functions in Health and Irritable Bowel Syndrome. (PubMed id 18511740)¹ Camilleri M....Zinsmeister A.R. (2008)
270. Prevalence of common disease-associated variants in Asian Indians. (PubMed id 18248681)¹ Pemberton T.J....Patel P.I. (2008)
271. The -1019 C/G polymorphism of the 5-HT1A receptor gene is associated with negative symptom response to risperidone treatment in schizophrenia patients. (PubMed id 18308786)¹ Wang L....He L. (2008)
272. Gene-load score of the renin-angiotensin-aldosterone system is associated with coronary heart disease in familial hypercholesterolaemia. (PubMed id 18413308)¹ van der Net J.B....Sijbrands E.J. (2008)
273. The associations among GNB3 C825T polymorphism, erectile dysfunction, and related risk factors. (PubMed id 18783529)¹ Lee Y.C....Chang L.L. (2008)
274. Ethnic and genetic determinants of cardiovascular response to the selective alpha 2-adrenoceptor agonist dexmedetomidine. (PubMed id 18071056)¹ Kurnik D....Stein C.M. (2008)
275. Association study of the G-protein beta3 subunit C825T polymorphism with disease progression an overall survival in patients with head and neck squamous cell carcinoma. (PubMed id 18990763)¹ Lehnerdt G.F....Frey U.H. (2008)
276. An exploratory study of the association of adrenergic and serotonergic genotype and gastrointestinal motor functions. (PubMed id 17971028)¹ Grudell A.B....Zinsmeister A.R. (2008)
277. Effectiveness of statins in the reduction of the risk of myocardial infarction is modified by the GNB3 C825T variant. (PubMed id 18551043)¹ Peters B.J....Klungel O.H. (2008)
278. Distribution of the GNB3 825C>T polymorphism among Brazilians: impact of population structure. (PubMed id 18058092)¹ Vargens D.D....Suarez-Kurtz G. (2008)
279. C825T G-protein beta3 subunit gene polymorphism, tilt test results and point score in syncopal patients. (PubMed id 18493717)¹ Lelonek M....Goch J.H. (2008)
280. Genetic risk factors for renal failure among North Indian ESRD patients. (PubMed id 18242170)¹ Tripathi G....Agrawal S. (2008)
281. G protein beta3 subunit C825T polymorphism modifies the presentation of temporal lobe epilepsy. (PubMed id 18439224)¹ Osberg S....Gjerstad L. (2008)
282. Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. (PubMed id 18660489)¹ Lu Y....Boer J.M. (2008)
283. Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. (PubMed id 19086053)¹ GratacA^s M....Carracedo A. (2008)
284. A polymorphism in the G protein beta3-subunit gene is associated with bone metastasis risk in breast cancer patients. (PubMed id 17978878)¹ Clar H....Windhager R. (2007)
285. Evidence for association of GABA(B) receptors with Kir3 channels and regulators of G protein signalling (RGS4) proteins. (PubMed id 17185339)¹ Fowler C.E....Slesinger P.A. (2007)
286. G protein beta3 polymorphism and triptan response in cluster headache. (PubMed id 17361120)¹ Schurks M....Rosskopf D. (2007)
287. Influence of the G-protein beta-3 subunit gene C825 T polymorphism on the clinical phenotype of newly diagnosed essential hypertension. (PubMed id 17330058)¹ Jerrard-Dunne P....Feely J. (2007)
288. A splice site polymorphism in the G-protein beta subunit influences antidepressant efficacy in depression. (PubMed id 17460549)¹ Wilkie M.J....Smith G. (2007)
289. The GNB3 C825T polymorphism and depression among subjects with alcohol dependence. (PubMed id 16897596)¹ Prestes A.P....Bau C.H. (2007)
290. Genetics and hypertension. (PubMed id 17341998)¹ Weder A.B. (2007)
291. Vasovagal syncope patients and the C825T GNB3 polymorphism. (PubMed id 17584726)¹ Lelonek M....Goch J.H. (2007)
292. A genetic association study of 5-HTT LPR and GNbeta3 C825T polymorphisms with irritable bowel syndrome. (PubMed id 17564628)¹ Saito Y.A....Talley N.J. (2007)
293. Contribution of several candidate gene polymorphisms in the determination of adiposity changes: results from the Quebec Family Study. (PubMed id 17299381)¹ Bouchard L....Perusse L. (2007)
294. Effects of lifestyle modification on the progression of coronary atherosclerosis, autonomic function, and angina--the role of GNB3 C825T polymorphism. (PubMed id 16569552)¹ Michalsen A....Dobos G.J. (2006)
295. G-protein beta3 subunit gene variant (C825T) is unlikely to have a significant influence on serum total cholesterol level in Japanese workers. (PubMed id 16443564)¹ Suwazono Y....Nogawa K. (2006)
296. Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes. (PubMed id 16284746)¹ Andersen G....Pedersen O. (2006)
297. Identification of Gnr1p, a negative regulator of G alpha signalling in Schizosaccharomyces pombe, and its complementation by human G beta subunits. (PubMed id 16884933)¹ Goddard A....Davey J. (2006)
298. G-protein beta3 subunit variant C825T is a risk factor for hypertension in Japanese females--a prospective cohort study over 5 years. (PubMed id 17044851)¹ Suwazono Y....Nogawa K. (2006)
299. Is there an association between GNbeta3-C825T genotype and lower functional gastrointestinal disorders? (PubMed id 16762621)¹ Andresen V....Zinsmeister A.R. (2006)
300. Role of C825T polymorphism of GNbeta3 gene in preeclampsia. (PubMed id 16867916)¹ Tang X....Kumar A. (2006)
301. A study of candidate genotypes associated with dyspepsia in a U.S. community. (PubMed id 16464220)¹ Camilleri C.E....Urrutia R. (2006)
302. G-protein beta-3 subunit C825T polymorphism, sodium and arterial blood pressure: a community-based study of Japanese men and women. (PubMed id 17044850)¹ Yamagishi K....Iso H. (2006)
303. The G protein beta3 subunit 825C allele is associated with sudden infant death due to infection. (PubMed id 16938762)¹ Hauge Opdal S....Ole Rognum T. (2006)
304. Pilot study of the G-protein beta3 subunit gene (C825T) polymorphism and clinical response to olanzapine or olanzapine-related weight gain in persons with schizophrenia. (PubMed id 16449941)¹ Bishop J.R....Miller D. (2006)
305. Association between a functional polymorphism in the renin-angiotensin system and completed suicide. (PubMed id 16736244)¹ Hishimoto A....Maeda K. (2006)
306. Association study of the G-protein beta3 subunit C825T polymorphism with disease progression in patients with bladder cancer. (PubMed id 16133558)¹ Eisenhardt A....Lummen G. (2005)
307. High-throughput mapping of a dynamic signaling network in mammalian cells. (PubMed id 15761153)¹ Barrios-Rodiles M....Wrana J.L. (2005)
308. GNB3 C825T polymorphism and response to anti-retroviral combination therapy in HIV-1-infected patients--a pilot study. (PubMed id 16354603)¹ Brockmeyer N.H....Siffert W. (2005)
309. The 825C/T polymorphism of G-protein beta3 subunit gene and risk of ischaemic stroke. (PubMed id 15920455)¹ Zhang L....Huang X. (2005)
310. G-protein beta3 subunit C825T polymorphism tends to be associated with seasonal variation in young male college students. (PubMed id 16110247)¹ Lee H.J....Kim L. (2005)
311. Seasonal affective disorder and the G-protein beta-3-subunit C825T polymorphism. (PubMed id 14744475)¹ Johansson C....Schalling M. (2004)
312. Effects of systemic endothelin A receptor antagonism in various vascular beds in men: in vivo interactions of the major blood pressure-regulating systems and associations with the GNB3 C825T polymorphism. (PubMed id 15536455)¹ Mitchell A....Wenzel R.R. (2004)
313. The T-allele of the C825T polymorphism is associated with higher arterial stiffness in young healthy males. (PubMed id 15037876)¹ Nurnberger J....Schafers R.F. (2004)
314. G-protein beta3 subunit gene C825T polymorphism in patients with vesico-ureteric reflux. (PubMed id 15337465)¹ Zagradisnik B....Gregoric A. (2004)
315. The influence of G-protein beta3-subunit gene and endothelial nitric oxide synthase gene in exon 7 polymorphisms on progression of autosomal dominant polycystic kidney disease. (PubMed id 15287194)¹ Reiterova J....Viklicky O. (2004)
316. [Prediction of genetic risk for hypertension] (PubMed id 15046042)⁴ Izawa H....Yokota M. (2004)
317. Cooperative effect of GNB3 825C>T and GPIIIa PI(A) polymorphisms in enhanced platelet aggregation. (PubMed id 12818251)¹ Frey U.H....Siffert W. (2003)
318. G-protein beta(3) subunit 825 C/T polymorphism is associated with weight gain during pregnancy. (PubMed id 12668921)¹ Dishy V....Stein C.M. (2003)
319. G protein subunit G gamma 13 is coexpressed with G alpha o, G beta 3, and G beta 4 in retinal ON bipolar cells. (PubMed id 12454992)¹ Huang L....Euler T. (2003)
320. Sildenafil response is influenced by the G protein beta 3 subunit GNB3 C825T polymorphism: a pilot study. (PubMed id 12576843)¹ Sperling H....Siffert W. (2003)
321. Glucagon and regulation of glucose metabolism. (PubMed id 12626323)¹ Jiang G. and Zhang B.B. (2003)
322. Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Complex formation of NDPK B with Gbeta gamma dimers and phosphorylation of His-266 IN Gbeta. (PubMed id 12486123)¹ Cuello F....Wieland T. (2003)
323. Prediction of successful weight reduction under sibutramine therapy through genotyping of the G-protein beta3 subunit gene (GNB3) C825T polymorphism. (PubMed id 12893983)¹ Hauner H....Siffert W. (2003)
324. Molecular genetics of microvascular disease in diabetic retinopathy. (PubMed id 12724690)⁴ Warpeha K.M. and Chakravarthy U. (2003)
325. Ambulatory blood pressure and left ventricular structure and function in relation to the G-protein beta3-subunit polymorphism C825T in White Europeans. (PubMed id 12756405)¹ Olszanecka A....Staessen J.A. (2003)
326. Association of gene polymorphisms with coronary artery disease in low- or high-risk subjects defined by conventional risk factors. (PubMed id 14563588)⁴ Hirashiki A....Yokota M. (2003)
327. Lack of association between the G protein beta3 subunit gene and essential hypertension in Chinese: a case-control and a family-based study. (PubMed id 13679998)¹ Huang X....Hui R. (2003)
328. A splice variant of the G protein beta 3-subunit implicated in disease states does not modulate ion channels. (PubMed id 12595577)¹ Ruiz-Velasco V. and Ikeda S.R. (2003)
329. Endogenous mono-ADP-ribosylation of the free Gbetagamma prevents stimulation of phosphoinositide 3-kinase-gamma and phospholipase C-beta2 and is activated by G-protein-coupled receptors. (PubMed id 12149126)¹ Lupi R....Di Girolamo M. (2002)
330. Matrix analysis for the dissection of interactions of G-protein beta3 subunit C825T genotype, allograft function, and posttransplant hypertension in kidney transplantation. (PubMed id 12460053)¹ Beige J....Offermann G. (2002)
331. Enhanced vasoconstriction to endothelin-1, angiotensin II and noradrenaline in carriers of the GNB3 825T allele in the skin microcirculation. (PubMed id 12172218)¹ Wenzel R.R....Schafers R.F. (2002)
332. Frequencies of the G-protein beta3 subunit C825T polymorphism and the delta 32 mutation of the chemokine receptor-5 in patients with multiple sclerosis. (PubMed id 12270649)¹ Haase C.G....Faustmann P.M. (2002)
333. The role of G protein beta subunits in the release of ATP from human erythrocytes. (PubMed id 12512701)¹ Sprague R.S....Lonigro A.J. (2002)
334. Effect of the (C825T) Gbeta(3) polymorphism on adrenoceptor-mediated lipolysis in human fat cells. (PubMed id 11978662)¹ Ryden M....Arner P. (2002)
335. Relation of the G protein beta3-subunit polymorphism with left ventricle structure and function. (PubMed id 12154107)¹ Sedlacek K....Schunkert H. (2002)
336. Positive association of maternal G protein beta3 subunit 825T allele with reduced head circumference at birth. (PubMed id 12409514)¹ Masuda K....Sekiya S. (2002)
337. Pharmacogenetics of antidepressant and mood-stabilizing drugs: a review of candidate-gene studies and future research directions. (PubMed id 12366879)⁴ Lerer B. and Macciardi F. (2002)
338. Physical activity does not mitigate G-protein-related genetic risk for obesity in individuals of African descent. (PubMed id 11930987)¹ Poston W.S....Forevt J.P. (2002)
339. G-protein beta3-subunit gene variant, blood pressure and erythrocyte sodium/lithium countertransport in essential hypertension. (PubMed id 12113397)¹ Poch E....De la Sierra A. (2002)
340. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
341. The human G-protein beta3 subunit C825T polymorphism is associated with coronary artery vasoconstriction. (PubMed id 11350093)⁴ Meirhaeghe A....Amouyel P. (2001)
342. G protein beta3 subunit variant: tendency of increasing susceptibility to hypertension in Japanese. (PubMed id 11688759)¹ Tozawa Y. (2001)
343. The C825T polymorphism in the G-protein beta3 subunit gene and diabetic complications in IDDM patients. (PubMed id 11322658)¹ Shcherbak N.S. and Schwartz E.I. (2001)
344. C825T polymorphism of the G protein beta(3)-subunit and antihypertensive response to a thiazide diuretic. (PubMed id 11230366)¹ Turner S.T....Boerwinkle E. (2001)
345. G-Protein beta(3)-subunit 825T allele is associated with enhanced human atrial inward rectifier potassium currents. (PubMed id 10931811)⁴ Dobrev D....Ravens U. (2000)
346. Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11. (PubMed id 10339615)¹ Snow B.E.... Siderovski D.P. (1999)
347. Donor G protein beta3 subunit 825TT genotype is associated with reduced kidney allograft survival. (PubMed id 10446939)⁴ Beige J....Sharma A.M. (1999)
348. The G protein subunit gene families. (PubMed id 10644457)¹ Downes G.B. and Gautam N. (1999)
349. Association between the C825T polymorphism of the G protein beta3-subunit gene and hypertension in blacks. (PubMed id 10601117)⁴ Dong Y....Cappuccio F.P. (1999)
350. Translocation of G-protein beta3 subunit from the cytosol pool to the membrane pool by beta1-adrenergic receptor stimulation in perfused rat hearts. (PubMed id 10513993)¹ Kageyama K....Kawaguchi H. (1999)
351. Association between a polymorphism in the G protein beta3 subunit gene and lower renin and elevated diastolic blood pressure levels. (PubMed id 9740618)⁴ Schunkert H....Siffert W. (1998)
352. The C825T polymorphism in the human G-protein beta3 subunit gene is not associated with diabetic nephropathy in Type I diabetes mellitus. (PubMed id 9833937)⁴ Fogarty D.G....Krolewski A.S. (1998)
353. A G protein gamma subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gbeta5 subunits. (PubMed id 9789084)¹ Snow B.E.... Siderovski D.P. (1998)
354. Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families. (PubMed id 8636150)¹ Yan K....Gautam N. (1996)
355. Intersubunit surfaces in G protein alpha beta gamma heterotrimers. Analysis by cross-linking and mutagenesis of beta gamma. (PubMed id 8550614)¹ Garcia-Higuera I....Neer E.J. (1996)
356. Lipid modifications of trimeric G proteins. (PubMed id 7822269)¹ Wedegaertner P.B....Bourne H.R. (1995)
357. Chromosomal localization of the genes encoding two forms of the G protein beta polypeptide, beta 1 and beta 3, in man. (PubMed id 1979057)¹ Levine M.A....O'Brien S.J. (1990)
358. Lack of GNB3 exon 9 polymorphism in primary hypertensive and normotensive dogs. (PubMed id 17496272)⁹ Kuppinger O....Schulz R. (2007)
359. Heritability of blood pressure traits and the genetic contribution to blood pressure variance explained by four blood-pressure-related genes. (PubMed id 17278972)⁹ van Rijn M.J....van Duijn C.M. (2007)
360. Mutation in the guanine nucleotide-binding protein beta-3 causes retinal degeneration and embryonic mortality in chickens. (PubMed id 17065478)⁹ Tummala H....Lester D.H. (2006)
361. Human G protein beta3 subunit variant does not alter hypercarbic or hypoxic ventilatory response. (PubMed id 11576163)⁹ Exner H.J....Peters J. (2001)
362. G-protein beta3 subunit gene (GNB3) polymorphism 825C-->T in patients with hypertensive crisis. (PubMed id 11008983)⁹ Buchmayer H....Fodinger M. (2000)
363. Selective absence of cone outer segment beta 3-transducin immunoreactivity in hereditary cone degeneration (cd). (PubMed id 8943701)⁹ Gropp K.E....Aguirre G.D. (1996)
364. Gene-gene interactions among genetic variants from ob esity candidate genes for nonobese and obese populations in type 2 diabetes. (PubMed id 19594364)⁹ Lin E....Wu L.S. (2009)
365. Chromosomal localization of 13 candidate genes for human obesity in the pig genome. (PubMed id 19029685)⁹ Nowacka-Woszuk J....Switonski M. (2008)
366. [Guanine nucleotide-binding protein beta 3 subunit (GNB3) gene polymorphism] (PubMed id 16895213)⁹ Ogimoto A. and Higaki J. (2006)
367. [Polymorphism in guanine nucleotide-binding protein (G-protein) beta 3 subunit (GNB3) gene as a risk factor in the development of hypertensive organ damage] (PubMed id 15171355)⁹ Ogimoto A. (2004)
368. G protein beta 3 polymorphism and hemodynamic and body composition phenotypes in the HERITAGE Family Study. (PubMed id 11875193)⁹ Rankinen T....Bouchard C. (2002)
369. [Genetic polymorphism of the G-protein beta3 subunit, obesity and essential hypertension] (PubMed id 10713907)⁹ Siffert W....Erbel R. (2000)
370. The G protein beta3 subunit splice variant Gbeta3-s causes enhanced chemotaxis of human neutrophils in response to interleukin-8. (PubMed id 10463330)⁹ Virchow S....Siffert W. (1999)
371. G-protein beta3 subunit gene (GNB3) variant in causation of essential hypertension. (PubMed id 9856980)⁹ Benjafield A.V....Morris B.J. (1998)
372. Association between beta-adrenergic receptor polymorphisms and their G-protein-coupled receptors with body mass index and obesity in women: a report from the NHLBI-sponsored WISE study. (PubMed id 15917856)⁹ Terra S.G....Johnson J.A. (2005)
373. Metabolic and haemodynamic effects of oral glucose loading in young healthy men carrying the 825T-allele of the G protein beta3 subunit. (PubMed id 12890290)⁹ Nurnberger J....Schafers R.F. (2003)
374. Haemodynamic characterization of young normotensive men carrying the 825T-allele of the G-protein beta3 subunit. (PubMed id 11505216)⁹ Schafers R.F....Michel M.C. (2001)
375. G protein beta3 subunit variant and essential hypertension in Taiwan - a case-control study. (PubMed id 10817859)⁹ Tsai C.H....Chang J.G. (2000)
376. G protein beta3 subunit polymorphism and risk of thrombosis and restenosis following coronary stent placement. (PubMed id 10704626)⁹ von Beckerath N....Schomig A. (2000)
377. G protein beta3 subunit variant and essential hypertension in Japanese. (PubMed id 9822456)⁹ Kato N....Yazaki Y. (1998)
378. Genetics and irritable bowel syndrome: from genomics to intermediate phenotype and pharmacogenetics. (PubMed id 19655247)⁹ Camilleri M. (2009)
379. Adrenergic gene polymorphisms and cardiovascular risk in the NHLBI-sponsored Women's Ischemia Syndrome Evaluation. (PubMed id 18331634)⁹ Pacanowski M.A....Johnson J.A. (2008)
380. Meta-analyses of genetic studies on major depressive disorder. (PubMed id 17938638)⁹ LA^pez-LeA^n S....van Duijn C.M. (2008)
381. Genetic determination of irritable bowel syndrome. (PubMed id 19034965)⁹ Hotoleanu C....Dumitrascu D.L. (2008)
382. Common single nucleotide polymorphisms in Japanese patients with essential hypertension: aldehyde dehydrogenase 2 gene as a risk factor independent of alcohol consumption. (PubMed id 17785925)⁹ Hui P....Cheng Z. (2007)
383. APOC3 promoter polymorphisms C-482T and T-455C are associated with the metabolic syndrome. (PubMed id 17416293)⁹ Miller M....Misra A. (2007)
384. Association of a beta-2 adrenoceptor (ADRB2) gene variant with a blunted in vivo lipolysis and fat oxidation. (PubMed id 17130852)⁹ Jocken J.W....Saris W.H. (2007)
385. Genetics of antipsychotic treatment emergent weight gain in schizophrenia. (PubMed id 16981847)⁹ Muller D.J. and Kennedy J.L. (2006)
386. [Genetics in neurocardiogenic syncope] (PubMed id 17642146)⁹ Lelonek M. (2006)
387. The influence of Serotonin Transporter Promoter Polymorphism (SERTPR) and other polymorphisms of the serotonin pathway on the efficacy of antidepressant treatments. (PubMed id 15939518)⁹ Serretti A....Smeraldi E. (2005)
388. Hypertension genes are genetic markers for insulin sensitivity and resistance. (PubMed id 15699455)⁹ Guo X....Rotter J.I. (2005)
389. Genetic features of antidepressant induced mania and hypo-mania in bipolar disorder. (PubMed id 15248044)⁹ Serretti A....Catalano M. (2004)
390. The pharmacogenomics of selective serotonin reuptake inhibitors. (PubMed id 15111987)⁹ Serretti A. and Artioli P. (2004)
391. Cardiovascular diseases and G-protein beta3 subunit gene (GNB3) in the era of genomewide scans. (PubMed id 12764399)⁹ Tomaszewski M....Dominiczak A.F. (2003)
392. Interaction of Gbeta3s, a splice variant of the G-protein Gbeta3, with Ggamma- and Galpha-proteins. (PubMed id 12639711)⁹ Rosskopf D....Siffert W. (2003)
393. G-protein beta3 subunit 825T allele and hypertension. (PubMed id 12530935)⁹ Siffert W. (2003)
394. The genetic determination of left ventricular mass in healthy adults. (PubMed id 12643891)⁹ Swan L....Hillis W.S. (2003)
395. Pharmacogenomics of diuretic drugs: data on rare monogenic disorders and on polymorphisms and requirements for further research. (PubMed id 14596636)⁹ Vormfelde S.V....Brockmoller J. (2003)

External Searches for GNB3 gene

Genome Databases showing GNB3 gene

Other Databases showing GNB3 gene

Specialized Databases showing GNB3 gene

Products
for GNB3 gene