Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



GNB3 Gene

protein-coding   GIFtS: 67
GCID: GC12P007133

Guanine Nucleotide Binding Protein (G Protein), Beta Polypeptide...

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Guanine Nucleotide Binding Protein (G Protein), Beta Polypeptide 31 2     Guanine Nucleotide-Binding Protein G(I)/G(S)/G(T) Beta Subunit 32
Transducin Beta Chain 32 3     Guanine Nucleotide-Binding Protein G(I)/G(S)/G(T) Subunit Beta-32
G Protein, Beta-3 Subunit2     Hypertension Associated Protein2
GTP-Binding Regulatory Protein Beta-3 Chain2     

External Ids:    HGNC: 44001   Entrez Gene: 27842   Ensembl: ENSG000001116647   OMIM: 1391305   UniProtKB: P165203   

Export aliases for GNB3 gene to outside databases

Previous GC identifers: GC12M007019 GC12M007103 GC12P006828 GC12P006819 GC12P006977 GC12P006981 GC12P006808 GC12P006989 GC12P007001 GC12P007010 GC12P007021 GC12P007045 GC12P007109


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for GNB3 Gene:
Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and
effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families
of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as
well as of certain signal transduction receptors and effectors. A single-nucleotide polymorphism (C825T) in this
gene is associated with essential hypertension and obesity. This polymorphism is also associated with the
occurrence of the splice variant GNB3-s, which appears to have increased activity. GNB3-s is an example of
alternative splicing caused by a nucleotide change outside of the splice donor and acceptor sites. Additional
splice variants may exist for this gene, but they have not been fully described. (provided by RefSeq, Jul 2008)

GeneCards Summary for GNB3 Gene:
GNB3 (guanine nucleotide binding protein (G protein), beta polypeptide 3) is a protein-coding gene. Diseases associated with GNB3 include syncope, and aortic coarctation. GO annotations related to this gene include GTPase binding and signal transducer activity. An important paralog of this gene is GNB2.

UniProtKB/Swiss-Prot: GBB3_HUMAN, P16520
Function: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various
transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement
of GDP by GTP, and for G protein-effector interaction

summary for GNB3 Gene:
Heterotrimeric G proteins are membrane bound GTPases that are linked to 7-TM receptors. Each G protein
contains an alpha-, beta- and gamma-subunit and is bound to GDP in the 'off' state. Ligand-receptor binding
results in detachment of the G protein, switching it to an 'on' state and permitting Galpha activation of
second messenger signalling cascades. There are several types of Galpha proteins; in addition, some
Gbetagamma subunits have active functions. Gbetagamma coupled to H1 receptors can activate PLA2 and
Gbetagamma coupled to M1 receptors can activate KIR channels.

Gene Wiki entry for GNB3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000012.12  NT_009759.17  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the GNB3 gene promoter:
         GATA-2   CREB   PPAR-alpha   PPAR-gamma1   deltaCREB   HSF2   PPAR-gamma2   ATF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGNB3 promoter sequence
   Search Chromatin IP Primers for GNB3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat GNB3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p13   Ensembl cytogenetic band:  12p13.31   HGNC cytogenetic band: 12p13

GNB3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GNB3 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P007133:  view genomic region     (about GC identifiers)

Start:
6,949,118 bp from pter      End:
6,956,557 bp from pter
Size:
7,440 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: GBB3_HUMAN, P16520 (See protein sequence)
Recommended Name: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3  
Size: 340 amino acids; 37221 Da
Subunit: G proteins are composed of 3 units, alpha, beta and gamma. Interacts with RASD2
Secondary accessions: Q9BQC0

Explore the universe of human proteins at neXtProt for GNB3: NX_P16520

Explore proteomics data for GNB3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See GNB3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_002066.1  
    ENSEMBL proteins: 
     ENSP00000229264   ENSP00000442002   ENSP00000439753   ENSP00000414734   ENSP00000444325  
     ENSP00000445967  
    Reactome Protein details: P16520

    GNB3 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for GNB3
    OriGene Custom MassSpec
    OriGene Custom Protein Services for GNB3
    GenScript Custom Purified and Recombinant Proteins Services for GNB3
    Novus Biologicals GNB3 Proteins
    Novus Biologicals GNB3 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

    GNB3 Antibody Products:

    EMD Millipore Mono- and Polyclonal Antibodies for the study of GNB3
    Browse R&D Systems for Antibodies
    Cell Signaling Technology (CST) Antibodies for GNB3 
    OriGene Antibodies for GNB3
    OriGene Custom Antibody Services for GNB3
    Novus Biologicals GNB3 Antibodies
    Abcam antibodies for GNB3
    Browse Antibodies at Cloud-Clone Corp.
    ThermoFisher Antibodies for GNB3
    LSBio Antibodies in human, mouse, rat for GNB3

    GNB3 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for GNB3
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for GNB3
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    HGNC Gene Families:
    WDR: WD repeat domain containing

    Selected InterPro protein domains (see all 7):
     IPR019775 WD40_repeat_CS
     IPR016346 Guanine_nucleotide-bd_bsu
     IPR001680 WD40_repeat
     IPR020472 G-protein_beta_WD-40_rep
     IPR001632 Gprotein_B

    Graphical View of Domain Structure for InterPro Entry P16520

    ProtoNet protein and cluster: P16520

    2 Blocks protein domains:
    IPB001632 Beta G-protein (transducin) signature
    IPB001680 G-protein beta WD-40 repeat signature


    UniProtKB/Swiss-Prot: GBB3_HUMAN, P16520
    Similarity: Belongs to the WD repeat G protein beta family
    Similarity: Contains 7 WD repeats


    GNB3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GBB3_HUMAN, P16520
    Function: Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various
    transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement
    of GDP by GTP, and for G protein-effector interaction

         Genatlas biochemistry entry for GNB3:
    guanine nucleotide binding protein (G protein),beta,polypeptide 3,with a shortened splice variant GNB3-s
    associated with essential hypertension and susceptibility factor in obesity in Inuits with the 825TT variant

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003924GTPase activity TAS9425898
    GO:0004871signal transducer activity IEA--
    GO:0005515protein binding IPI--
    GO:0051020GTPase binding IPI19255495
         
    GNB3 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for GNB3:
     Increased gamma-H2AX phosphory 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Gnb3):
     mortality/aging  nervous system  vision/eye 

    GNB3 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Gnb3tm1(KOMP)Vlcg for GNB3

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for GNB3
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for GNB3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for GNB3
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for GNB3

    miRNA
    Products:
        
    miRTarBase miRNAs that target GNB3:
    hsa-mir-26b-5p (MIRT029954)

    Block miRNA regulation of human, mouse, rat GNB3 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate GNB3:
    hsa-miR-186* hsa-miR-3675-5p hsa-miR-486-3p
    SwitchGear 3'UTR luciferase reporter plasmidGNB3 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for GNB3
    Predesigned siRNA for gene silencing in human, mouse, rat GNB3

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for GNB3

    Clone
    Products:
         
    OriGene clones in human, mouse for GNB3 (see all 14)
    OriGene ORF clones in mouse, rat for GNB3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: GNB3 (NM_002075)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for GNB3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GNB3

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for GNB3
    Browse ESI BIO Cell Lines and PureStem Progenitors for GNB3 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GNB3


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane4
    cytosol3
    nucleus2
    endoplasmic reticulum1
    extracellular1
    golgi apparatus1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS--
    GO:0043005neuron projection IEA--
    GO:0044297cell body IEA--

    GNB3 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus

    SuperPaths for GNB3 About   (see all 72)                                                                                              See pathways by source

    SuperPathSelected contained pathways About (see all per SuperPath)
    1ADP signalling through P2Y purinoceptor 12
    G-protein beta-gamma signalling0.90
    Thrombin signalling through proteinase activated receptors (PARs)0.69
    G beta-gamma signalling through PI3Kgamma0.90
    Activation of Kainate Receptors upon glutamate binding0.68
    Signal amplification0.79
    Inhibition of Insulin Secretion by Adrenaline/Noradrenaline0.64
    ADP signalling through P2Y purinoceptor 10.79
    Glucagon-type ligand receptors0.61
    2fMLP Pathway
    CCR3 Pathway in Eosinophils0.44
    CXCR4 Pathway0.39
    VEGF and S-1P Signaling0.44
    Alpha-Adrenergic Signaling0.38
    fMLP Pathway0.43
    Huntington's Disease Pathway0.30
    Signal transduction Activation of PKC via G Protein coupled receptor0.42
    3Development Dopamine D2 receptor transactivation of EGFR
    Development Dopamine D2 receptor transactivation of EGFR0.66
    Apoptosis and survival BAD phosphorylation0.41
    Development Alpha 2 adrenergic receptor activation of ERK0.66
    BAD Phosphorylation0.41
    Chemotaxis CXCR4 signaling pathway0.48
    4Regulation of Water Balance by Renal Aquaporins
    Regulation of Water Balance by Renal Aquaporins0.85
    Glucagon signaling in metabolic regulation0.70
    Aquaporin-mediated transport0.85
    Cytoskeleton remodeling Role of PKA in cytoskeleton reorganisation0.40
    5EphB-EphrinB Signaling
    EphB-EphrinB Signaling0.58
    Cytoskeleton remodeling Reverse signaling by ephrin B0.34
    Ephrin-Eph Signaling0.58

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    Selected Downloadable PowerPoint Slides of GeneGlobe Pathway Central Maps for GNB3 (see all 71)
        Molecular Mechanisms of Cancer
    Intracellular Calcium Signaling
    CDK5 Pathway
    JNK Pathway
    ERK5 Signaling

    2 Cell Signaling Technology (CST) Pathways for GNB3
        Ca, cAMP and Lipid Signaling
    Neuroscience

    Selected GeneGo (Thomson Reuters) Pathways for GNB3 (see all 34)
        Signal transduction cAMP signaling
    G-protein signaling Regulation of p38 and JNK signaling mediated by G-proteins
    G-protein signaling G-Protein alpha-i signaling cascades
    Inhibitory action of Lipoxins and Resolvin E1 on neutrophil functions
    Signal transduction Activation of PKC via G-Protein coupled receptor

    Selected BioSystems Pathways for GNB3 (see all 6)
        Myometrial Relaxation and Contraction Pathways
    G Protein Signaling Pathways
    SIDS Susceptibility Pathways
    Calcium Regulation in the Cardiac Cell
    Corticotropin-releasing hormone

    Selected Reactome Pathways for GNB3 (see all 23)
        G alpha (12/13) signalling events
    G alpha (z) signalling events
    G-protein activation
    Ca2+ pathway
    Thromboxane signalling through TP receptor

    2 PharmGKB Pathways for GNB3
        Beta-agonist/Beta-blocker Pathway, Pharmacodynamics
    Platelet Aggregation Inhibitor Pathway, Pharmacodynamics

    Selected Kegg Pathways  (Kegg details for GNB3) (see all 13):
        Ras signaling pathway
    Chemokine signaling pathway
    PI3K-Akt signaling pathway
    Circadian entrainment
    Retrograde endocannabinoid signaling


    GNB3 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for GNB3
    Interactions:

        GeneGlobe Interaction Network for GNB3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for GNB3 (P165202, 3 ENSP000002292644) via UniProtKB, MINT, STRING, and/or I2D (see all 683) (see top 5)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GNG3P632153, ENSP000002941174I2D: score=2 STRING: ENSP00000294117
    GNG4P501503, ENSP000003555564I2D: score=2 STRING: ENSP00000355556
    GNG5P632183, ENSP000003596754I2D: score=2 STRING: ENSP00000359675
    GNG13Q9P2W33, ENSP000002481504I2D: score=1 STRING: ENSP00000248150
    GNG7O602623, ENSP000003715944I2D: score=2 STRING: ENSP00000371594
    ESR2Q927313, ENSP000003439254I2D: score=1 STRING: ENSP00000343925
    CDC5LQ994592, ENSP000003605324MINT-7947479 STRING: ENSP00000360532
    XPO5Q9HAV42, ENSP000002653514MINT-7947479 STRING: ENSP00000265351
    TGFBR1P368973, ENSP000003641334I2D: score=3 STRING: ENSP00000364133
    PAK4O960132, ENSP000003510494MINT-7947479 STRING: ENSP00000351049
    GNASP630922, ENSP000003601414MINT-7947479 STRING: ENSP00000360141
    SKIV2L2P422852, ENSP000002306404MINT-7947479 STRING: ENSP00000230640
    AXIN2Q9Y2T13I2D: score=1 
    CSNK1A1P487293I2D: score=1 
    CSNK1EP496743I2D: score=1 
    GSK3BP498413I2D: score=1 
    ABCF1Q8NE712MINT-7947479
    ABCF3Q9NUQ82MINT-7947479
    ACTBP607092MINT-7947479
    ACTL6AO960192MINT-7947479
    ACTR1AP611632MINT-7947479
    ACTR2P611602MINT-7947479
    ADNPQ9H2P02MINT-7947479
    AHNAKQ096662MINT-7947479
    AKAP8O438232MINT-7947479
    ANAPC1Q9H1A42MINT-7947479
    ANAPC2Q9UJX62MINT-7947479
    ANAPC7Q9UJX32MINT-7947479
    ANLNQ9NQW62MINT-7947479
    ANXA11P509952MINT-7947479
    AP1B1Q105672MINT-7947479
    ARCN1P484442MINT-7947479
    ARGLU1Q9NWB62MINT-7947479
    ARHGEF1Q928882MINT-7947479
    ARHGEF2Q929742MINT-7947479
    ARID1AO144972MINT-7947479
    AURKBQ96GD42MINT-7947479
    BAZ1AQ9NRL22MINT-7947479
    BCAS2O759342MINT-7947479
    BCLAF1Q9NYF82MINT-7947479
    BIDP559572MINT-7947479
    BRD2P254402MINT-7947479
    BRD4O608852MINT-7947479
    BRD7Q9NPI12MINT-7947479
    BRD8Q9H0E92MINT-7947479
    BTAF1O149812MINT-7947479
    BUB1O436832MINT-7947479
    BUB1BO605662MINT-7947479
    BUB3O436842MINT-7947479
    BZW1Q7L1Q62MINT-7947479
    C7orf13Q8NI282MINT-7947479
    CAPGP401212MINT-7947479
    CAPZA1P529072MINT-7947479
    CARD10Q9BWT72MINT-7947479
    CASC5Q8NG312MINT-7947479
    CCNB1P146352MINT-7947479
    CCT2P783712MINT-7947479
    CCT3P493682MINT-7947479
    CCT4P509912MINT-7947479
    CCT5P486432MINT-7947479
    CCT6AP402272MINT-7947479
    CCT7Q998322MINT-7947479
    CCT8P509902MINT-7947479
    CDC16Q130422MINT-7947479
    CDC20Q128342MINT-7947479
    CDC23Q9UJX22MINT-7947479
    CDC27P302602MINT-7947479
    CDC73Q6P1J92MINT-7947479
    CDK9P507502MINT-7947479
    CDKN2AIPQ9NXV62MINT-7947479
    CHD1LQ86WJ12MINT-7947479
    CHD8Q9HCK82MINT-7947479
    CHEK1O147572MINT-7947479
    CKAP5Q140082MINT-7947479
    CLASP1Q7Z4602MINT-7947479
    CLINT1Q146772MINT-7947479
    CNOT10Q9H9A52MINT-7947479
    CNOT3O751752MINT-7947479
    COPAP536212MINT-7947479
    COPB1P536182MINT-7947479
    COPB2P356062MINT-7947479
    COPG1Q9Y6782MINT-7947479
    COPG2Q9UBF22MINT-7947479
    COPS5Q929052MINT-7947479
    CPSF2Q9P2I02MINT-7947479
    CPSF3Q9UKF62MINT-7947479
    CPSF7Q8N6842MINT-7947479
    CSE1LP550602MINT-7947479
    CSTF3Q129962MINT-7947479
    CTNND1O607162MINT-7947479
    CUL1Q136162MINT-7947479
    CWC15Q9P0132MINT-7947479
    DCTN2Q135612MINT-7947479
    DDB1Q165312MINT-7947479
    DDX17Q928412MINT-7947479
    DDX19AQ9NUU72MINT-7947479
    DDX19BQ9UMR22MINT-7947479
    DDX39AO001482MINT-7947479
    DDX39BQ138382MINT-7947479
    DDX3XO005712MINT-7947479
    DDX41Q9UJV92MINT-7947479
    DDX42Q86XP32MINT-7947479
    DDX47Q9H0S42MINT-7947479
    DDX5P178442MINT-7947479
    DDX6P261962MINT-7947479
    DEPDC7Q96QD52MINT-7947479
    DFNA5O604432MINT-7947479
    DIAPH1O606102MINT-7947479
    DIDO1Q9BTC02MINT-7947479
    DMAP1Q9NPF52MINT-7947479
    DNAJA1P316892MINT-7947479
    DNM1LO004292MINT-7947479
    DNM2P505702MINT-7947479
    DOCK5Q9H7D02MINT-7947479
    DOCK8Q8NF502MINT-7947479
    DRG1Q9Y2952MINT-7947479
    DSPP159242MINT-7947479
    DTYMKP239192MINT-7947479
    DYNC1H1Q142042MINT-7947479
    DYNC1LI1Q9Y6G92MINT-7947479
    DYNC1LI2O432372MINT-7947479
    ECT2Q9H8V32MINT-7947479
    EDC4Q6P2E92MINT-7947479
    EEF1A1P681042MINT-7947479
    EFTUD2Q150292MINT-7947479
    EHD1Q9H4M92MINT-7947479
    EHD4Q9H2232MINT-7947479
    EHMT1Q9H9B12MINT-7947479
    EIF2B4Q9UI102MINT-7947479
    EIF2DP412142MINT-7947479
    EIF2S3P410912MINT-7947479
    EIF3BP558842MINT-7947479
    EIF3GO758212MINT-7947479
    EIF3IQ133472MINT-7947479
    EIF4A1P608422MINT-7947479
    EIF4A2Q142402MINT-7947479
    EIF4A3P389192MINT-7947479
    EIF4G2P783442MINT-7947479
    EIF5BO608412MINT-7947479
    ELAVL1Q157172MINT-7947479
    ELF2Q157232MINT-7947479
    ENAHQ8N8S72MINT-7947479
    ENSG00000183311P074372MINT-7947479
    ENSG00000206289P287022MINT-7947479
    ENSG00000206490Q8NE712MINT-7947479
    ENSG00000215077P254402MINT-7947479
    ENSG00000215425Q138382MINT-7947479
    ENSG00000224156P074372MINT-7947479
    ENSG00000225073Q138382MINT-7947479
    ENSG00000225859Q138382MINT-7947479
    ENSG00000225989Q8NE712MINT-7947479
    ENSG00000227322P287022MINT-7947479
    ENSG00000227739P074372MINT-7947479
    ENSG00000228333P287022MINT-7947479
    ENSG00000229496Q138382MINT-7947479
    ENSG00000229684P074372MINT-7947479
    ENSG00000230624Q138382MINT-7947479
    ENSG00000231129Q8NE712MINT-7947479
    ENSG00000231321P287022MINT-7947479
    ENSG00000232169Q8NE712MINT-7947479
    ENSG00000232421P074372MINT-7947479
    ENSG00000232575P074372MINT-7947479
    ENSG00000234507P254402MINT-7947479
    ENSG00000234704P254402MINT-7947479
    ENSG00000235067P074372MINT-7947479
    ENSG00000235307P254402MINT-7947479
    ENSG00000235439Q138382MINT-7947479
    ENSG00000235712P287022MINT-7947479
    ENSG00000236149Q8NE712MINT-7947479
    ENSG00000236342Q8NE712MINT-7947479
    EPB41L3Q9Y2J22MINT-7947479
    EPPK1P581072MINT-7947479
    EPS8L2Q9H6S32MINT-7947479
    ERAL1O756162MINT-7947479
    ERCC1P079922MINT-7947479
    ERCC6LQ2NKX82MINT-7947479
    ETF1P624952MINT-7947479
    ETV6P412122MINT-7947479
    EWSR1Q018442MINT-7947479
    EXOC2Q96KP12MINT-7947479
    EXOC4Q96A652MINT-7947479
    EXOC5O004712MINT-7947479
    EXOC7Q9UPT52MINT-7947479
    EXOSC10Q017802MINT-7947479
    FAF1Q9UNN52MINT-7947479
    FAM129BQ96TA12MINT-7947479
    FANCD2Q9BXW92MINT-7947479
    FANCIQ9NVI12MINT-7947479
    FASNP493272MINT-7947479
    FEN1P397482MINT-7947479
    FERMT1Q9BQL62MINT-7947479
    FHOD1Q9Y6132MINT-7947479
    FUSP356372MINT-7947479
    GAPDHP044062MINT-7947479
    GATAD2AQ86YP42MINT-7947479
    GCN1L1Q926162MINT-7947479
    GEMIN4P576782MINT-7947479
    GEMIN6Q8WXD52MINT-7947479
    GMPSP499152MINT-7947479
    GOLGB1Q147892MINT-7947479
    GPS2Q132272MINT-7947479
    GTF2IP783472MINT-7947479
    GTF3C2Q8WUA42MINT-7947479
    GTF3C5Q9Y5Q82MINT-7947479
    GTPBP1O001782MINT-7947479
    GULP1Q9UBP92MINT-7947479
    HAUS7Q998712MINT-7947479
    HBS1LQ9Y4502MINT-7947479
    HDAC1Q135472MINT-7947479
    HDAC2Q927692MINT-7947479
    HDLBPQ003412MINT-7947479
    HELLSQ9NRZ92MINT-7947479
    HIC2Q96JB32MINT-7947479
    HIP1RO751462MINT-7947479
    HIRAP541982MINT-7947479
    HLTFQ145272MINT-7947479
    HNRNPA2B1P226262MINT-7947479
    HNRNPCP079102MINT-7947479
    HNRNPFP525972MINT-7947479
    HNRNPH1P319432MINT-7947479
    HNRNPKP619782MINT-7947479
    HNRNPMP522722MINT-7947479
    HNRNPUQ008392MINT-7947479
    HSP90AA1P079002MINT-7947479
    HSP90AB1P082382MINT-7947479
    HSP90B1P146252MINT-7947479
    HSPA12AO433012MINT-7947479
    HSPA5P110212MINT-7947479
    HSPA6P170662MINT-7947479
    HSPA8P111422MINT-7947479
    HSPB1P047922MINT-7947479
    HSPD1P108092MINT-7947479
    HUWE1Q7Z6Z72MINT-7947479
    IKBKAPO951632MINT-7947479
    ILF2Q129052MINT-7947479
    INTS1Q8N2012MINT-7947479
    INTS3Q68E012MINT-7947479
    INTS6Q9UL032MINT-7947479
    INTS8Q75QN22MINT-7947479
    IPO5O004102MINT-7947479
    IPO7O953732MINT-7947479
    IPO9Q96P702MINT-7947479
    IQGAP1P469402MINT-7947479
    ITPK1Q135722MINT-7947479
    KANSL1Q7Z3B32MINT-7947479
    KDM1AO603412MINT-7947479
    KHDRBS1Q076662MINT-7947479
    KIF11P527322MINT-7947479
    KIF21AQ7Z4S62MINT-7947479
    KIF2CQ996612MINT-7947479
    KIF4AO952392MINT-7947479
    KPNA2P522922MINT-7947479
    KPNB1Q149742MINT-7947479
    LAS1LQ9Y4W22MINT-7947479
    LENG9Q96B702MINT-7947479
    LIMS1P480592MINT-7947479
    LMNAP025452MINT-7947479
    LMO7Q8WWI12MINT-7947479
    LRRC1Q9BTT62MINT-7947479
    LRRC40Q9H9A62MINT-7947479
    LRWD1Q9UFC02MINT-7947479
    MAD1L1Q9Y6D92MINT-7947479
    MAGEE2Q8TD902MINT-7947479
    MAP2K4P459852MINT-7947479
    MAP2K7O147332MINT-7947479
    MAP7Q142442MINT-7947479
    MARK2Q7KZI72MINT-7947479
    MATR3P432432MINT-7947479
    MDN1Q9NU222MINT-7947479
    MED12Q930742MINT-7947479
    MED12LQ86YW92MINT-7947479
    MED16Q9Y2X02MINT-7947479
    MED4Q9NPJ62MINT-7947479
    MELKQ146802MINT-7947479
    MPP2Q141682MINT-7947479
    MRE11AP499592MINT-7947479
    MSH2P432462MINT-7947479
    MSH6P527012MINT-7947479
    MTA2O947762MINT-7947479
    MTA3Q9BTC82MINT-7947479
    MTCL1Q9Y4B52MINT-7947479
    MVPQ147642MINT-7947479
    MYBBP1AQ9BQG02MINT-7947479
    MYH9P355792MINT-7947479
    MYO15BQ96JP22MINT-7947479
    NACC1Q96RE72MINT-7947479
    NAT10Q9H0A02MINT-7947479
    NBNO609342MINT-7947479
    NCAPD2Q150212MINT-7947479
    NCAPHQ150032MINT-7947479
    NCOR1O753762MINT-7947479
    NDC80O147772MINT-7947479
    NELFBQ8WX922MINT-7947479
    NF1P213592MINT-7947479
    NIPBLQ6KC792MINT-7947479
    NONOQ152332MINT-7947479
    NPM1P067482MINT-7947479
    NRG1Q022972MINT-7947479
    NSFP464592MINT-7947479
    NSUN5Q96P112MINT-7947479
    NUDCQ9Y2662MINT-7947479
    NUDT21O438092MINT-7947479
    NUF2Q9BZD42MINT-7947479
    NUP107P577402MINT-7947479
    NUP155O756942MINT-7947479
    NUP93Q8N1F72MINT-7947479
    ORC2Q134162MINT-7947479
    ORC3Q9UBD52MINT-7947479
    OXSR1O957472MINT-7947479
    PARP1P098742MINT-7947479
    PARVAQ9NVD72MINT-7947479
    PARVBQ9HBI12MINT-7947479
    PCBP1Q153652MINT-7947479
    PCBP2Q153662MINT-7947479
    PCNTO956132MINT-7947479
    PDLIM7Q9NR122MINT-7947479
    PELOQ9BRX22MINT-7947479
    PFKMP082372MINT-7947479
    PFKPQ018132MINT-7947479
    PHGDHO431752MINT-7947479
    PICALMQ134922MINT-7947479
    PKN2Q165132MINT-7947479
    PLECQ151492MINT-7947479
    PLK1P533502MINT-7947479
    PLRG1O436602MINT-7947479
    PNNQ9H3072MINT-7947479
    POLD1P283402MINT-7947479
    POLR1CO151602MINT-7947479
    POLR3DP054232MINT-7947479
    POLR3EQ9NVU02MINT-7947479
    PPFIA1Q131362MINT-7947479
    PPM1DO152972MINT-7947479
    PPP1CAP621362MINT-7947479
    PPP2R1AP301532MINT-7947479
    PRCCQ927332MINT-7947479
    PRKDCP785272MINT-7947479
    PRPF19Q9UMS42MINT-7947479
    PRPF3O433952MINT-7947479
    PRPF4BQ135232MINT-7947479
    PRPF6O949062MINT-7947479
    PRPF8Q6P2Q92MINT-7947479
    PSMC1P621912MINT-7947479
    PSMC2P359982MINT-7947479
    PSMC3P179802MINT-7947479
    PSMC4P436862MINT-7947479
    PSMC5P621952MINT-7947479
    PSMC6P623332MINT-7947479
    PSMD1Q994602MINT-7947479
    PSMD11O002312MINT-7947479
    PSMD12O002322MINT-7947479
    PSMD13Q9UNM62MINT-7947479
    PSMD2Q132002MINT-7947479
    PSMD3O432422MINT-7947479
    PSTPIP2Q9H9392MINT-7947479
    PTBP1P265992MINT-7947479
    PTBP2Q9UKA92MINT-7947479
    PTBP3O957582MINT-7947479
    PUM1Q146712MINT-7947479
    RACGAP1Q9H0H52MINT-7947479
    RAD18Q9NS912MINT-7947479
    RAD50Q928782MINT-7947479
    RALYQ9UKM92MINT-7947479
    RANBP2P497922MINT-7947479
    RANGAP1P460602MINT-7947479
    RAVER1Q8IY672MINT-7947479
    RBBP4Q090282MINT-7947479
    RBBP5Q152912MINT-7947479
    RBBP7Q165762MINT-7947479
    RBM17Q96I252MINT-7947479
    RBM39Q144982MINT-7947479
    RBM4Q9BWF32MINT-7947479
    RBM45Q8IUH32MINT-7947479
    RBM7Q9Y5802MINT-7947479
    RBMXP381592MINT-7947479
    RCOR1Q9UKL02MINT-7947479
    RFC2P352502MINT-7947479
    RFC3P409382MINT-7947479
    RFC4P352492MINT-7947479
    RFC5P409372MINT-7947479
    RFX1P226702MINT-7947479
    RFX5P483822MINT-7947479
    RIF1Q5UIP02MINT-7947479
    RNF130Q86XS82MINT-7947479
    RNF17Q9BXT82MINT-7947479
    ROCK2O751162MINT-7947479
    RPL13P263732MINT-7947479
    RPL22P352682MINT-7947479
    RPL24P837312MINT-7947479
    RPL31P628992MINT-7947479
    RPLP0P053882MINT-7947479
    RPS13P622772MINT-7947479
    RPS6KA4O756762MINT-7947479
    RPS6KB2Q9UBS02MINT-7947479
    RTCBQ9Y3I02MINT-7947479
    RUVBL1Q9Y2652MINT-7947479
    RUVBL2Q9Y2302MINT-7947479
    RXRBP287022MINT-7947479
    SART1O432902MINT-7947479
    SCAF8Q9UPN62MINT-7947479
    SCRIBQ141602MINT-7947479
    SCYL2Q6P3W72MINT-7947479
    SEC23AQ154362MINT-7947479
    SEC24CP539922MINT-7947479
    SEH1LQ96EE32MINT-7947479
    SENP3Q9H4L42MINT-7947479
    SEPT9Q9UHD82MINT-7947479
    SETXQ7Z3332MINT-7947479
    SF3A1Q154592MINT-7947479
    SF3A2Q154282MINT-7947479
    SF3A3Q128742MINT-7947479
    SF3B1O755332MINT-7947479
    SF3B2Q134352MINT-7947479
    SF3B3Q153932MINT-7947479
    SF3B6Q9Y3B42MINT-7947479
    SFPQP232462MINT-7947479
    SHC1P293532MINT-7947479
    SHROOM3Q8TF722MINT-7947479
    SIN3AQ96ST32MINT-7947479
    SMARCA5O602642MINT-7947479
    SMARCAD1Q9H4L72MINT-7947479
    SMARCB1Q128242MINT-7947479
    SMARCC1Q929222MINT-7947479
    SMARCC2Q8TAQ22MINT-7947479
    SMARCD1Q96GM52MINT-7947479
    SMARCE1Q969G32MINT-7947479
    SMC1AQ146832MINT-7947479
    SMC2O953472MINT-7947479
    SMC3Q9UQE72MINT-7947479
    SMC4Q9NTJ32MINT-7947479
    SMCHD1A6NHR92MINT-7947479
    SMN1Q166372MINT-7947479
    SMN2Q166372MINT-7947479
    SNAPC4Q5SXM22MINT-7947479
    SNRNP200O756432MINT-7947479
    SNRNP40Q96DI72MINT-7947479
    SNRNP70P086212MINT-7947479
    SNRPAP090122MINT-7947479
    SNRPA1P096612MINT-7947479
    SNRPD1P623142MINT-7947479
    SNRPD3P623182MINT-7947479
    SNRPEP623042MINT-7947479
    SNW1Q135732MINT-7947479
    SNX12Q9UMY42MINT-7947479
    SNX2O607492MINT-7947479
    SPATA5Q8NB902MINT-7947479
    SPENQ96T582MINT-7947479
    SPTAN1Q138132MINT-7947479
    SPTBN1Q010822MINT-7947479
    SREK1Q8WXA92MINT-7947479
    SRP54P610112MINT-7947479
    SRP68Q9UHB92MINT-7947479
    SRP72O760942MINT-7947479
    SRRM1Q8IYB32MINT-7947479
    SRSF1Q079552MINT-7947479
    SRSF4Q081702MINT-7947479
    SRSF7Q166292MINT-7947479
    SSUH2Q9Y2M22MINT-7947479
    STAB1Q9NY152MINT-7947479
    STAG2Q8N3U42MINT-7947479
    STAT3P407632MINT-7947479
    STK24Q9Y6E02MINT-7947479
    SUGT1Q9Y2Z02MINT-7947479
    SUMO1P631652MINT-7947479
    SUPT16HQ9Y5B92MINT-7947479
    SYMPKQ927972MINT-7947479
    TAF15Q928042MINT-7947479
    TAF5LO755292MINT-7947479
    TANC2Q9HCD62MINT-7947479
    TARDBPQ131482MINT-7947479
    TBL1XR1Q9BZK72MINT-7947479
    TCP1P179872MINT-7947479
    THAP1Q9NVV92MINT-7947479
    THRAP3Q9Y2W12MINT-7947479
    TIAL1Q010852MINT-7947479
    TLN1Q9Y4902MINT-7947479
    TLN2Q9Y4G62MINT-7947479
    TMOD3Q9NYL92MINT-7947479
    TMPOP421662MINT-7947479
    TNFAIP2Q031692MINT-7947479
    TNKS1BP1Q9C0C22MINT-7947479
    TNPO1Q929732MINT-7947479
    TPRP122702MINT-7947479
    TPX2Q9ULW02MINT-7947479
    TRAP1Q129312MINT-7947479
    TRIM21P194742MINT-7947479
    TRIM28Q132632MINT-7947479
    TRIP13Q156452MINT-7947479
    TRMT1LQ7Z2T52MINT-7947479
    TRRAPQ9Y4A52MINT-7947479
    TRUB1Q8WWH52MINT-7947479
    TSG101Q998162MINT-7947479
    TUBA1CQ9BQE32MINT-7947479
    TUBA4AP683662MINT-7947479
    TUBBP074372MINT-7947479
    TUBB4BP683712MINT-7947479
    TUBG1P232582MINT-7947479
    TUBGCP2Q9BSJ22MINT-7947479
    TUBGCP3Q96CW52MINT-7947479
    TUBGCP4Q9UGJ12MINT-7947479
    TWF1Q127922MINT-7947479
    U2AF1Q010812MINT-7947479
    U2AF2P263682MINT-7947479
    U2SURPO150422MINT-7947479
    UBA5Q9GZZ92MINT-7947479
    UBE2MP610812MINT-7947479
    UBE2NP610882MINT-7947479
    UBE2SQ167632MINT-7947479
    UBL4AP114412MINT-7947479
    UBN1Q9NPG32MINT-7947479
    UCHL5Q9Y5K52MINT-7947479
    UMPSP111722MINT-7947479
    UNC45AQ9H3U12MINT-7947479
    UPF1Q929002MINT-7947479
    UPF2Q9HAU52MINT-7947479
    USO1O607632MINT-7947479
    USP10Q146942MINT-7947479
    USP24Q9UPU52MINT-7947479
    USP39Q53GS92MINT-7947479
    VIMP086702MINT-7947479
    VPS33AQ96AX12MINT-7947479
    VPS33BQ9H2672MINT-7947479
    VPS36Q86VN12MINT-7947479
    VPS51Q9UID32MINT-7947479
    WDR18Q9BV382MINT-7947479
    WDR33Q9C0J82MINT-7947479
    WRNIP1Q96S552MINT-7947479
    XRN2Q9H0D62MINT-7947479
    YEATS4O956192MINT-7947479
    YLPM1P497502MINT-7947479
    YWHAEP622582MINT-7947479
    ZBTB7CA1YPR02MINT-7947479
    ZC3HC1Q86WB02MINT-7947479
    ZNF638Q149662MINT-7947479
    ARHGEF38ENSP000002651544STRING: ENSP00000416125 STRING: ENSP00000265154
    ADCY1ENSP000002973234STRING: ENSP00000297323
    ADCY2ENSP000003429524STRING: ENSP00000342952
    ADCY4ENSP000003121264STRING: ENSP00000312126
    ADCY5ENSP000004193614STRING: ENSP00000419361
    ADCY6ENSP000003114054STRING: ENSP00000311405
    ADCY7ENSP000002542354STRING: ENSP00000254235
    ADCY9ENSP000002940164STRING: ENSP00000294016
    GCGRENSP000003835584STRING: ENSP00000383558
    GNAT2ENSP000002513374STRING: ENSP00000251337
    GNAT3ENSP000003813394STRING: ENSP00000381339
    GNG11ENSP000002485644STRING: ENSP00000248564
    GNG12ENSP000003600214STRING: ENSP00000360021
    GNG2ENSP000003344484STRING: ENSP00000334448
    GNGT2ENSP000003004064STRING: ENSP00000300406
    PCSK1ENSP000003080244STRING: ENSP00000308024
    ADCY8ENSP000002863554STRING: ENSP00000286355
    GABBR2ENSP000002594554STRING: ENSP00000259455
    GCGENSP000003876624STRING: ENSP00000387662
    GNG8ENSP000003008734STRING: ENSP00000300873
    ADCY3ENSP000002606004STRING: ENSP00000260600
    CACNA1AENSP000003533624STRING: ENSP00000353362
    CACNA1BENSP000002775494STRING: ENSP00000277549
    CHRM2ENSP000003199844STRING: ENSP00000319984
    CHRM4ENSP000004093784STRING: ENSP00000409378
    GNAI1ENSP000003430274STRING: ENSP00000343027
    GNAI2ENSP000003129994STRING: ENSP00000312999
    GNAI3ENSP000003588674STRING: ENSP00000358867
    KCNJ3ENSP000002951014STRING: ENSP00000295101
    PIK3CAENSP000002639674STRING: ENSP00000263967
    PIK3CBENSP000002891534STRING: ENSP00000289153
    PIK3CDENSP000003665634STRING: ENSP00000366563
    PIK3CGENSP000003521214STRING: ENSP00000352121
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006112energy reserve metabolic process TAS--
    GO:0006184GTP catabolic process TAS9425898
    GO:0007186G-protein coupled receptor signaling pathway TAS2107550
    GO:0007268synaptic transmission TAS--
    GO:0008217regulation of blood pressure TAS9425898

    GNB3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Compounds for GNB3 available from Tocris Bioscience    About this table
    CompoundAction CAS #
    GalleinInhibitor of betagamma signaling[2103-64-2]
    Suramin hexasodium saltNon-selective P2 antagonist[129-46-4]
    G-Protein antagonist peptideInhibits G protein activation by GPCRs[143675-79-0]
    8-Bromo-cGMP, sodium salt cGMP analog; activates PKG[51116-01-9]
    Pertussis Toxin Catalyzes ADP-ribosylation of Gi, Go and Gt [70323-44-3]

    3 HMDB Compounds for GNB3    About this table
    CompoundSynonyms CAS #PubMed Ids
    Guanosine diphosphate5'-GDP (see all 10)146-91-8--
    Guanosine monophosphate5'-GMP (see all 14)85-32-5--
    Guanosine triphosphate5'-GTP (see all 10)86-01-1--

    Selected Novoseek inferred chemical compound relationships for GNB3 gene (see all 19)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    nppa 62.9 2 17036337 (1), 15699455 (1)
    sibutramine 56.7 6 20359253 (2), 19687782 (2)
    thiazide 46.9 2 16450155 (1)
    sodium 31.5 4 9886871 (1), 11259340 (1), 16002097 (1), 17642146 (1)
    guanine 30.4 10 17065478 (2), 15171355 (1), 19301222 (1), 18325076 (1) (see all 5)
    clozapine 20.9 6 16141801 (2), 15179018 (1), 18855531 (1)
    clonidine 20.7 1 12844135 (1)
    hydrochlorothiazide 14.1 1 16450155 (1)
    cholesterol 8.22 4 10701813 (2), 11434508 (1), 15042113 (1)
    norepinephrine 7.47 3 16513451 (1), 17544870 (1), 17642146 (1)

    Selected PharmGKB related drug/compound annotations for GNB3 gene (see all 11)    About this table
    Drug/compound PharmGKB Annotation
    antidepressantsCA  
    atorvastatinCA  
    fluvastatinCA  
    hmg coa reductase inhibitorsCA  
    lovastatinCA  
    olanzapineCA  
    pravastatinCA  
    rosuvastatinCA  
    sildenafilCA  
    simvastatinCA  



    GNB3 for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for GNB3 gene: 
    NM_002075.2  

    Unigene Cluster for GNB3:

    Guanine nucleotide binding protein (G protein), beta polypeptide 3
    Hs.631657  [show with all ESTs]
    Unigene Representative Sequence: AB209283
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000540458(uc001qrc.3) ENST00000229264(uc001qrd.3 uc009zfe.3)
    ENST00000541257 ENST00000541978 ENST00000435982 ENST00000539127 ENST00000542868
    ENST00000537035 ENST00000542751
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat GNB3 using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate GNB3:
    hsa-miR-186* hsa-miR-3675-5p hsa-miR-486-3p
    SwitchGear 3'UTR luciferase reporter plasmidGNB3 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for GNB3
    Predesigned siRNA for gene silencing in human, mouse, rat GNB3
    Clone
    Products:
         
    OriGene clones in human, mouse for GNB3 (see all 14)
    OriGene ORF clones in mouse, rat for GNB3
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: GNB3 (NM_002075)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for GNB3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GNB3
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for GNB3
    OriGene qSTAR qPCR primer pairs in human, mouse for GNB3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat GNB3
      QuantiTect SYBR Green Assays in human, mouse, rat GNB3
      QuantiFast Probe-based Assays in human, mouse, rat GNB3

    Additional mRNA sequence: 

    AB209283.1 AB593098.1 AB593099.1 AF501884.1 AK313091.1 BC000115.1 BC002454.2 BC015920.1 
    BT009800.1 M31328.1 U47930.1 

    9 DOTS entries:

    DT.121170390  DT.112163  DT.95155927  DT.121170335  DT.100779698  DT.40115198  DT.40265129  DT.95155920 
    DT.102841594 

    9 AceView cDNA sequences:

    NM_002075 U47931 U47930 BC002454 BC000115 BC015920 AF501884 M31328 
    BT009800 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for GNB3 (see all 7)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b ^ 12
    SP1:                                            -     -                                               -                     
    SP2:                                            -     -                                               -     -               
    SP3:                                            -     -                                               -                     
    SP4:                                            -     -                                                                     
    SP5:                                            -                                                                           


    ECgene alternative splicing isoforms for GNB3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    GNB3 expression in normal human tissues (normalized intensities)      GNB3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTTTCTCCTT
    GNB3 Expression
    About this image


    GNB3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
             Midbrain dopaminergic-like neurons
     
     Neurons
             Mature Rod Bipolar Cells Inner Nuclear Layer
             Midbrain dopaminergic-like neurons
     
     Eye (Sensory Organs)
             Mature Rod Bipolar Cells Inner Nuclear Layer
     
     Ovary (Reproductive System)
             Oviduct
    GNB3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    GNB3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.631657
        Custom PCR Arrays for GNB3
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for GNB3
    OriGene qSTAR qPCR primer pairs in human, mouse for GNB3
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat GNB3
    QuantiTect SYBR Green Assays in human, mouse, rat GNB3
    QuantiFast Probe-based Assays in human, mouse, rat GNB3
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GNB3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals.

    Orthologs for GNB3 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gnb31 , 5 guanine nucleotide binding protein (G protein), beta more1, 5 89.8(n)1
    97.06(a)1
      6 (59.17 cM)5
    146951  NM_013530.11  NP_038558.11 
     1248342405 
    chicken
    (Gallus gallus)
    Aves GNB31 guanine nucleotide binding protein (G protein), beta more 81.96(n)
    93.24(a)
      427945  XM_004938118.1  XP_004938175.1 
    lizard
    (Anolis carolinensis)
    Reptilia GNB36
    guanine nucleotide binding protein (G protein), be...
    90(a)
    1 ↔ 1
    GL343453.1(391066-403708)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia gnb31 guanine nucleotide binding protein (G protein), beta more 77.55(n)
    88.24(a)
      496520  NM_001011107.1  NP_001011107.1 
    zebrafish
    (Danio rerio)
    Actinopterygii gnb3a1 guanine nucleotide binding protein (G protein), beta more 71.96(n)
    79.71(a)
      436710  NM_001002437.1  NP_001002437.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta G&bgr;13F3 G-protein coupled receptor protein
    signaling pathway more
    77(a)
    (best of 2)
      13F16   --
    worm
    (Caenorhabditis elegans)
    Secernentea gpb-13 guanine nucleotide-binding protein beta
    subunit
    81(a)   II(11743881-11747549)   --


    ENSEMBL Gene Tree for GNB3 (if available)
    TreeFam Gene Tree for GNB3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for GNB3 gene
    GNB22  GNB12  WDR472  GNB52  GNB42  
    7 SIMAP similar genes for GNB3 using alignment to 8 protein entries:     GBB3_HUMAN (see all proteins):
    GNB1    GNB4    GNB2    GNB5    WDR61    PF20
    WDR82

    GNB3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for GNB3 (see all 292)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs454538001,2
    C,F--6803600(+) TCTCTA/GTGGCC 1 -- int14Minor allele frequency- G:0.22WA CSA EA 242
    rs799912961,2
    C--6803633(+) CCTCCC/AGGCTG 1 -- int12Minor allele frequency- A:0.14WA 120
    rs1931841601,2
    --6803678(+) CCCTCC/TCCCCA 1 -- int10--------
    rs1468436601,2
    --6878844(+) AGGGCC/TGCCTT 1 -- us2k10--------
    rs1397292731,2
    --6878847(+) GCCGCC/GTTGAC 1 -- us2k10--------
    rs1905958831,2
    C--6878879(+) TTCTGA/CGGTTT 1 -- us2k10--------
    rs1496863161,2
    --6878916(+) TAGTAC/TGTATT 1 -- us2k10--------
    rs774106211,2
    F--6878937(+) ATTGTA/GGGAAG 1 -- us2k11Minor allele frequency- G:0.01WA 118
    rs1833058231,2
    --6878964(+) CCTAAA/TAGAAT 1 -- us2k10--------
    rs37593471,2
    C,F,A,H--6878978(+) GCAGCG/ACCTGG 1 -- us2k117Minor allele frequency- A:0.29NS EA NA WA 2340

    HapMap Linkage Disequilibrium report for GNB3 (6949118 - 6956557 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for GNB3:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv898641CNV Loss21882294
    dgv1353n71CNV Loss21882294
    nsv832323CNV Loss17160897
    nsv898638CNV Loss21882294
    nsv832324CNV Loss17160897

    Human Gene Mutation Database (HGMD): GNB3
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing GNB3
    DNA2.0 Custom Variant and Variant Library Synthesis for GNB3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 139130   
    OMIM disorders: 145500  
    Selected diseases for GNB3 (see all 77):    About MalaCards
    syncope    aortic coarctation    essential hypertension    nephropathy-hypertension
    irritable bowel syndrome    dyspepsia    seasonal affective disorder    hypertension
    carotid stenosis    cluster headache    headache    thyroid adenoma
    mood disorder    tardive dyskinesia    adrenal adenoma    gastroesophageal reflux disease
    obesity    major depressive disorder    obesity, association with    bipolar disorder

    1 disease from the University of Copenhagen DISEASES database for GNB3:
    Hypertension

    GNB3 for disorders           About GeneDecksing

    Selected Novoseek inferred disease relationships for GNB3 gene (see all 31)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    essential hypertension 79.1 39 10817859 (2), 19811352 (2), 15042113 (2), 17278960 (1) (see all 28)
    obesity 60.9 59 15090636 (3), 12730030 (3), 19065529 (2), 19594364 (2) (see all 30)
    genetic susceptibility 53.9 1 10713907 (1)
    hypertension arterial 52 8 11230982 (3), 11816511 (1), 12439636 (1), 15332573 (1) (see all 6)
    ventricular hypertrophy 41.1 2 12011775 (1), 15332573 (1)
    thyroid adenoma 38.5 1 17136758 (1)
    major depression 32.3 10 14647404 (2), 16302021 (1), 17943025 (1), 12476328 (1) (see all 7)
    insulin resistance 31.9 10 12930636 (3), 11121369 (1), 12624279 (1), 17161225 (1) (see all 6)
    mood disorders 28 3 11586049 (2), 11992559 (1)
    schizophrenia 26.5 4 16139171 (1), 16141801 (1), 16964080 (1), 10884039 (1)

    Genetic Association Database (GAD): GNB3
    Human Genome Epidemiology (HuGE) Navigator: GNB3 (294 documents)

    Export disorders for GNB3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for GNB3 gene, integrated from 10 sources (see all 415):
    (articles sorted by number of sources associating them with GNB3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and ethnic distribution of major haplotypes in the gene GNB3 encoding the G-protein beta3 subunit. (PubMed id 11927836)1, 4, 9 Rosskopf D....Siffert W. (Pharmacogenetics 2002)
    2. Homozygous 825T allele of the GNB3 protein influences the susceptibility of Japanese to dyspepsia. (PubMed id 17717746)1, 4, 9 Tahara T....Nakano H. (Dig. Dis. Sci. 2008)
    3. G-protein beta3 subunit (GNB3) gene polymorphisms and cardiovascular disease: the Ludwigshafen Risk and Cardiovascular Health (LURIC) study. (PubMed id 16908025)1, 4, 9 Renner W....MAorz W. (Atherosclerosis 2007)
    4. The 825C&gt;T polymorphism of the G-protein beta-3 subunit gene (GNB3) and breast cancer. (PubMed id 15019160)1, 4, 9 Krippl P....Samonigg H. (Cancer Lett. 2004)
    5. GNB3 gene C825T and ACE gene I/D polymorphisms in essential hypertension in a Kazakh genetic isolate. (PubMed id 15042113)1, 4, 9 Wang X....Wen H. (J Hum Hypertens 2004)
    6. G protein beta 3 gene: structure, promoter, and additional polymorphisms. (PubMed id 10904009)1, 2, 9 Rosskopf D.... Siffert W. (Hypertension 2000)
    7. [Association of alpha-adducin gene and G-protein beta3-subunit gene with essential hypertension in Chinese]. (PubMed id 17825147)1, 4, 9 Huang X.H....Hui R.T. (Zhonghua Yi Xue Za Zhi 2007)
    8. [Association between G-protein beta3 subunit (GNB(3)) gene C825T polymorphism, hypertension, insulin resistance and obesity]. (PubMed id 12930636)1, 4, 9 Chen Y.Y....Hui R.T. (Zhonghua Yi Xue Za Zhi 2003)
    9. A preliminary candidate genotype-intermediate phenotype study of satiation and gastric motor function in obesity. (PubMed id 19876010)1, 4, 9 Papathanasopoulos A....Zinsmeister A.R. (Obesity (Silver Spring) 2010)
    10. [Analysis of the GNB3 gene 825C/T polymorphism in non-obese and obese Chinese]. (PubMed id 19065529)1, 4, 9 Wang X....Liu B. (Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 2784 HGNC: 4400 AceView: GNB3 Ensembl:ENSG00000111664 euGenes: HUgn2784
    ECgene: GNB3 Kegg: 2784 H-InvDB: GNB3

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for GNB3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for GNB3 gene:
    Search GeneIP for patents involving GNB3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     Browse Purified and Recombinant Proteins at EMD Millipore
     EMD Millipore Mono- and Polyclonal Antibodies for the study of GNB3
     Browse Kits and Assays available from EMD Millipore
     Browse Small Molecules at EMD Millipore
     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for GNB3   OriGene RNAi products in human, mouse, rat for GNB3  
     OriGene qPCR primer pairs and template standards for GNB3   OriGene Protein Over-expression Lysate for GNB3  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for GNB3  
     OriGene qSTAR qPCR primer pairs in human, mouse for GNB3   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for GNB3   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for GNB3   OriGene Custom Protein Services for GNB3  

     
     
     Block miRNA regulation of human, mouse, rat GNB3 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing GNB3
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat GNB3 Predesigned siRNA for gene silencing in human, mouse, rat GNB3
     QuantiFast Probe-based Assays in human, mouse, rat GNB3 QuantiTect SYBR Green Assays in human, mouse, rat GNB3
     Custom PCR Arrays for GNB3 Search Chromatin IP Primers for GNB3
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat GNB3  GeneGlobe Interaction Network for GNB3
     Regulatory tfbs in GNB3 promoter
     GenScript Custom Purified and Recombinant Proteins Services for GNB3 GenScript cDNA clones with any tag delivered in your preferred vector for GNB3
     GenScript Custom Assay Services for GNB3 GenScript Custom overexpressing Cell Line Services for GNB3
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Antibodies & Assays for GNB3 

     Tocris compounds for GNB3
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     GNB3 antibodies
     GNB3 proteins
     GNB3 lysates
     Antibodies for GNB3
     See all of Abcam's Antibodies, Kits and Proteins for GNB3
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for GNB3
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GNB3
     SwitchGear 3'UTR luciferase reporter plasmids for GNB3
     SwitchGear Promoter luciferase reporter plasmids for GNB3
     ThermoFisher Antibodies for GNB3
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GNB3
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for GNB3
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for GNB3
     LSBio Antibodies in human, mouse, rat for GNB3
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      GNB3 gene at Home site.
    Version: 3.12.136 22 July 2014
    hostname: 356980-web2.xennexinc.com index build: 126 solr: 1.4