Aliases for GNA13 Gene
External Ids for GNA13 Gene
Previous GeneCards Identifiers for GNA13 Gene
GeneCards Summary for GNA13 Gene
GNA13 (G Protein Subunit Alpha 13) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and CXCR4-mediated signaling events. GO annotations related to this gene include GTP binding and signal transducer activity. An important paralog of this gene is GNA12.
UniProtKB/Swiss-Prot for GNA13 Gene
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems.
Heterotrimeric G proteins are membrane bound GTPases that are linked to 7-TM receptors. Each G protein contains an alpha-, beta- and gamma-subunit and is bound to GDP in the 'off' state. Ligand binding causes a receptor conformational change, detaching the G protein and switching it 'on'.