Aliases for GNA13 Gene
External Ids for GNA13 Gene
Previous GeneCards Identifiers for GNA13 Gene
GeneCards Summary for GNA13 Gene
GNA13 (Guanine Nucleotide Binding Protein (G Protein), Alpha 13) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Regulation of actin cytoskeleton. GO annotations related to this gene include GTP binding and signal transducer activity. An important paralog of this gene is GNAQ.
UniProtKB/Swiss-Prot for GNA13 Gene
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems
Heterotrimeric G proteins are membrane bound GTPases that are linked to 7-TM receptors. Each G protein contains an alpha-, beta- and gamma-subunit and is bound to GDP in the 'off' state. Ligand binding causes a receptor conformational change, detaching the G protein and switching it 'on'.