GMPS Gene
protein-coding GIFtS: 64
GCID: GC03P155588
|
|
guanine monphosphate synthetase
| |
Aliases
for GMPS gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Guanine Monphosphate Synthetase1 2 | | GMP Synthase2 | | Glutamine Amidotransferase2 3 | | GMP Synthase [Glutamine-Hydrolyzing]2 | | GMP Synthetase2 3 | | Guanosine 5'-Monophosphate Synthase2 | | EC 6.3.5.23 8 | | MLL/GMPS Fusion Protein2 |
Export aliases for GMPS gene to outside databasesPrevious GC identifers: GC03P152441 GC03P156575 GC03P156869 GC03P156909 GC03P157071 GC03P152982 |
Summaries
for GMPS gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for GMPS:
In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway divergesto the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymesinvolved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, andGMP synthetase, which catalyzes the amination of XMP to GMP. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: GUAA_HUMAN, P49915Function: Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNAsynthesis, but also provide GTP, which is involved in a number of cellular processes important for cell division
Gene Wiki entry for GMPS (GMP synthase)
|
Genomic Views
for GMPS gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000003.11 NC_018914.1 NT_005612.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the GMPS gene promoter:
E2F-4 E2F-3a E2F-5 E2F-1 E2F p53 E2F-2 C/EBPalpha
Other transcription factors
Search SABiosciences Chromatin IP Primers for GMPS
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GMPS |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 3q24 Ensembl cytogenetic band: 3q25.31 HGNC cytogenetic band: 3q25.31GMPS Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 3 GeneLoc Exon Structure GeneLoc location for GC03P155588: view genomic region
(about GC identifiers)
Start:
|
155,588,325 bp from pter |
End:
|
155,658,457 bp from pter |
Size:
|
70,133 bases |
Orientation:
|
plus strand |
|
Proteins
for GMPS gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: GUAA_HUMAN, P49915 (See
protein sequence)Recommended Name: GMP synthase [glutamine-hydrolyzing] Size: 693 amino acids; 76715 Da
Subunit: Homodimer (By similarity)
Subcellular location: Cytoplasm
2 PDB 3D structures from  and Proteopedia  for GMPS:2VPI (3D)
2VXO (3D)
Explore the universe of human proteins at neXtProt for GMPS: NX_P49915
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P49915
4/9 DME Specific Peptides for GMPS (P49915) (see all 9)
GMPS Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_003866.1
ENSEMBL proteins: ENSP00000419851 ENSP00000295920 ENSP00000438199 Reactome Protein details: P49915
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005829 | cytosol |
TAS | -- |
GMPS for ontologies About GeneDecksing
GMPS Antibody Products:
Assay Products for GMPS: |
Protein
Domains /
Families
for GMPS gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
GMPS for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry P49915ProtoNet protein and cluster: P49915 3 Blocks protein families: IPB000991 Glutamine amidotransferase class-I IPB001674 GMP synthase IPB006220 Anthranilate synthase component II signature
UniProtKB/Swiss-Prot: GUAA_HUMAN, P49915Similarity: Contains 1 glutamine amidotransferase type-1 domainSimilarity: Contains 1 GMPS ATP-PPase (ATP pyrophosphatase) domain |
Function
for GMPS gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: GUAA_HUMAN, P49915Function: Involved in the de novo synthesis of guanine nucleotides which are not only essential for DNA and RNAsynthesis, but also provide GTP, which is involved in a number of cellular processes important for cell divisionCatalytic activity: ATP + xanthosine 5'-phosphate + L-glutamine + H(2)O = AMP + diphosphate + GMP + L-glutamate Genatlas biochemistry entry for GMPS:guanosine 5'-monophosphate synthetase
Enzyme Number (IUBMB): EC 6.3.5.21 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GMPS (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GMPS
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: GMPS (NM_003875) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for GMPS | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GMPS |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GMPS |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
GMPS for ontologies About GeneDecksing
|
Pathways & Interactions
for GMPS gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/6 super-pathways (see all 6) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Purine metabolism | | | 2 | purine nucleotides de novo biosynthesis II | | | 3 | Metabolism | | | 4 | Purine metabolism | | | 5 | Antimetabolite Pathway - Folate Cycle, Pharmacodynamics | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for GMPS
4 
Reactome Pathways for GMPS
1  PharmGKB Pathway for GMPS
3 
Kegg Pathways (Kegg details for GMPS):
UniProtKB/Swiss-Prot: GUAA_HUMAN, P49915Pathway: Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1
GMPS for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GMPS
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/617 Interacting proteins for GMPS (P499152, 3 ENSP000004198514) via UniProtKB, MINT, STRING, and/or I2D (see all 617)
About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006144 | purine nucleobase metabolic process |
TAS | -- | | GO:0006177 | GMP biosynthetic process |
-- | -- | | GO:0006541 | glutamine metabolic process |
IEA | -- | | GO:0009113 | purine nucleobase biosynthetic process |
TAS | 8089153 | | GO:0009168 | purine ribonucleoside monophosphate biosynthetic process |
TAS | -- |
GMPS for ontologies About GeneDecksing
|
Drugs & Compounds
for GMPS gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
GMPS for compounds About GeneDecksing
 |
Enzo Life Sciences drugs & compounds for GMPS |
 Browse Tocris compounds for GMPS
10/12 HMDB Compounds for GMPS (see all 12) About this table
2 DrugBank Compounds for GMPS About this table
10/20 Novoseek chemical compound relationships for GMPS gene (see all 20) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| prfar |
95 |
1 |
16142895 (1) |
| imidazole glycerol phosphate |
92.6 |
5 |
15363855 (1), 15849257 (1), 16142895 (1) |
| decoyinine |
90.6 |
3 |
7706277 (1), 8527935 (1), 2391493 (1) |
| xanthosine-5'-monophosphate |
82.9 |
5 |
7706277 (3), 7559506 (1) |
| guanylate |
78.1 |
56 |
7706277 (7), 7559506 (6), 8089153 (6), 8527935 (6) (see all 17) |
| glutamine |
77.6 |
45 |
17159152 (2), 7559506 (2), 16030023 (2), 16142895 (2) (see all 26) |
| carbamoyl phosphate |
73.1 |
4 |
11080587 (1), 2347042 (1), 1348059 (1) |
| acivicin |
67.3 |
2 |
7559506 (2) |
| pyridoxal 5-phosphate |
58.3 |
6 |
19074821 (1), 17159152 (1), 16030023 (1) |
| aicar |
56.6 |
2 |
16859645 (1), 16142895 (1) |
Search CenterWatch for drugs/clinical trials and news about GMPS / GUAA
|
Transcripts
for GMPS gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for GMPS gene: NM_003875.2 Unigene Cluster for GMPS: Guanine monphosphate synthetase Hs.591314 [show with all ESTs]Unigene Representative Sequence: NM_0038754 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000496455(uc003faq.3 uc011bom.2) ENST00000295920 ENST00000476145
ENST00000541628
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GMPS (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GMPS
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: GMPS (NM_003875) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for GMPS | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GMPS |
Additional cDNA sequence: AF297746.1 AK223399.1 AK291504.1 AK300787.1 AK302148.1 AK315832.1 BC012178.1 U10860.1 13 DOTS entries: DT.413706 DT.92023667 DT.92024864 DT.100795441 DT.100823193 DT.95106687 DT.100823194 DT.95106665 DT.100804905 DT.86845422 DT.91744093 DT.95106676 DT.95106677 24/245 AceView cDNA sequences (see all 245): D25791 CB127348 AI873729 AA644165 BM849835 BQ228938 BU608935 BM793289 AV698752 AU124968 BU742463 CA418318 BQ652073 CB158353 CD513575 BX504924 AI378367 AL602533 BU616867 BQ431882 AI460161 CA946398 AW651755 BQ928370
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for GMPS About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 |
|---|
|
| SP1: | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for GMPS
|
Expression
for GMPS gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| GMPS expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACTGGTATAC
About this image
See GMPS Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for GMPS
SOURCE GeneReport for Unigene cluster: Hs.591314
SABiosciences Custom PCR Arrays for GMPS
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GMPS
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat GMPS | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GMPS | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GMPS | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GMPS |
Orthologs
for GMPS gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for GMPS gene from 10/36 species (see all 36) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Gmps1 , 5 |
guanine monophosphate synthetase1, 5 |
91.58(n)1
97.98(a)1 |
|
3 (30.08 cM)5
2293631 NM_001033300.21 NP_001028472.21
639761065 |
chicken
(Gallus gallus) |
Aves |
GMPS1 |
guanine monphosphate synthetase |
82.83(n)
94.52(a) |
|
425028 NM_001006556.1 NP_001006556.1 |
lizard
(Anolis carolinensis) |
Reptilia |
GMPS6 |
-- |
94(a) |
1 ↔ 1 |
3(15762857-15790768) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.111472 |
Xenopus laevis transcribed sequence with strong similarity more |
80.83(n) |
|
CD326062.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc660022 |
guanine monophosphate synthetase |
77.12(n) |
|
393559 BC056730.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
bur1 , 3 |
GMP biosynthesis GMP synthase (glutamine
hydrolyzing)3
burgundy1 |
58(a)3
58.28(n)1
59.67(a)1 |
|
458301 NM_138759.31 NP_620114.31 |
worm
(Caenorhabditis elegans) |
Secernentea |
M106.41 , 3 |
GMP synthase3
Protein M106.41 |
51(a)3
56.2(n)1
54.67(a)1 |
|
II(10864066-10865188)3
1746721 NM_001083162.21 NP_001076631.11 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT1G636606 |
GMP-synthase-C and glutamine amidotransferase doma... |
35(a) |
1 ↔ 1 |
1(23603935-23607275) |
rice
(Oryza sativa) |
Liliopsida |
-- |
class I glutamine amidotransferase, putative, expr... |
36(a) |
1 ↔ 1 |
8(14354255-14358335) |
E. coli
(Escherichia coli) |
Gamma proteobacteria |
guaA6 |
GMP synthetase (glutamine aminotransferase) |
37(a) |
1 ↔ 1 |
Chromosome(2628980-2630557) |
ENSEMBL Gene Tree for GMPS (if available)
TreeFam Gene Tree for GMPS (if available) |
Paralogs
for GMPS gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for GMPS gene
GMPS for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for GMPS
PGOHUM00000245819 PGOHUM00000233168
|
Genomic Variants
for GMPS gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 3 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for GMPS (155588325 - 155658457 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for GMPS: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GMPS |
|
Disorders
/ Diseases
for GMPS gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
GMPS for disorders About GeneDecksing
OMIM gene information: 600358
OMIM disorders: 601626
UniProtKB/Swiss-Prot: GUAA_HUMAN, P49915
Note=A chromosomal aberration involving GMPS is found in acute myeloid leukemias. Translocationt(3,11)(q25,q23) with MLL
12  diseases for GMPS: About MalaCardsacute myeloid leukemia intrahepatic cholangiocarcinoma myeloid leukemia insulin resistance
cholangiocarcinoma oral cancer leukemia pneumonia
schizophrenia tuberculosis malaria mycobacterium tuberculosis
1 Novoseek disease relationship for GMPS gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| tumors |
0 |
1 |
1353938 (1) |
Human Genome Epidemiology (HuGE) Navigator: GMPS (3 documents)
Export disorders for GMPS gene to outside databases
|
Publications
for GMPS gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for GMPS gene, integrated from 9 sources (see all 87):
(articles sorted by number of sources associating them with GMPS) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Human GMP synthetase. Protein purification, cloning, and functional expression of cDNA. (PubMed id 8089153)1, 2, 3, 9 Hirst M.... Lou L. (1994)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- t(3;11) translocation in treatment-related acute myeloid leukemia fuses MLL with the GMPS (guanosine 5-prime monophosphate synthetase) gene. (PubMed id 11110714)1, 2 Pegram L.D.... Felix C.A. (2000)
- Assignment and ordering of twenty-three unique NotI-linking clones containing expressed genes including the guanosine 5'-monophosphate synthetase gene to human chromosome 3. (PubMed id 9195163)1, 3 Fedorova L....Zabarovsky E.R. (1997)
- Biochemical characterization of human GMP synthetase. (PubMed id 7706277)1, 9 Nakamura J. and Lou L. (1995)
- The glutamine hydrolysis function of human GMP synthetase. Identification of an essential active site cysteine. (PubMed id 7559506)1, 9 Nakamura J....Lou L. (1995)
- Glutamine-dependent nitrogen transfer in Escherichia coli asparagine synthetase B. Searching for the catalytic triad. (PubMed id 7907328)7, 9 Boehlein S.K....Schuster S.M. (1994)
- Structure of a bacterial pyridoxal 5'-phosphate synthase complex. (PubMed id 17159152)7, 9 Strohmeier M....Tews I. (2006)
- GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7. (PubMed id 15749019)1, 9 van der Knaap J.A....Verrijzer C.P. (2005)
- Reaction coupling through interdomain contacts in imidazole glycerol phosphate synthase. (PubMed id 16142895)7, 9 Myers R.S....Davisson V.J. (2005)
|
External Searches for GMPS gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing GMPS gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing GMPS gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing GMPS gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for GMPS gene:
Search GeneIP for patents involving GMPS
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for GMPS gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for GMPS | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GMPS | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GMPS | | | OriGene Protein Over-expression Lysate for GMPS | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for GMPS | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GMPS | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GMPS | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for GMPS | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for GMPS | | OriGene Custom Protein Services for GMPS | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat GMPS | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GMPS | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GMPS | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GMPS | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GMPS | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GMPS |
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| | | | Search Tocris compounds for GMPS |
| |  |  |  |  | | | | | | Recombinant Protein for GMPS |
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 | | | GMPS Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GMPS |
|  |  |  | | | | Search ThermoFisher Antibodies for GMPS |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GMPS |
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