Aliases for GMPR Gene
External Ids for GMPR Gene
Previous GeneCards Identifiers for GMPR Gene
This gene encodes an enzyme that catalyzes the irreversible and NADPH-dependent reductive deamination of GMP to IMP. The protein also functions in the re-utilization of free intracellular bases and purine nucleosides.[provided by RefSeq, Oct 2009]
GeneCards Summary for GMPR Gene
GMPR (Guanosine Monophosphate Reductase) is a Protein Coding gene. Among its related pathways are Purine metabolism (REACTOME) and Purine metabolism (KEGG). GO annotations related to this gene include GMP reductase activity. An important paralog of this gene is GMPR2.
UniProtKB/Swiss-Prot for GMPR Gene
Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides.