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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GMIP Gene

protein-coding   GIFtS: 53
GCID: GC19M019740

GEM interacting protein

 Explore 3 diseases affiliated with
GMIP via our new
 Human Malady Compendium 
Biological research products
for GMIP
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
GEM Interacting Protein1 2
ARHGAP461 2
GEM-Interacting Protein2

External Ids:    HGNC: 248521   Entrez Gene: 512912   Ensembl: ENSG000000896397   OMIM: 6096945   UniProtKB: Q9P1073   

Export aliases for GMIP gene to outside databases

Previous GC identifers: GC19M020131 GC19M019585 GC19M019602 GC19M019603 GC19M019604 GC19M019302


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GMIP:
This gene encodes a member of the ARHGAP family of Rho/Rac/Cdc42-like GTPase activating proteins. The encoded protein
interacts with the Ras-related protein Gem through its N-terminal domain. Separately, it interacts with RhoA through a
RhoGAP domain, and stimulates RhoA-dependent GTPase activity. Alternatively spliced variants that encode different
protein isoforms have been described but their full-length nature has not been determined. (provided by RefSeq, Jul
2008)

UniProtKB/Swiss-Prot: GMIP_HUMAN, Q9P107
Function: Stimulates, in vitro and in vivo, the GTPase activity of RhoA




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011295.11  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GMIP gene promoter:
         Pax-5   p53   Olf-1   Lmo2   Roaz   PPAR-gamma1   SEF-1 (1)   PPAR-gamma2   TGIF   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGMIP promoter sequence
   Search SABiosciences Chromatin IP Primers for GMIP

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GMIP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.11   Ensembl cytogenetic band:  19p13.11   HGNC cytogenetic band: 19p13.11

GMIP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GMIP gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M019740:  view genomic region     (about GC identifiers)

Start:
19,740,285 bp from pter      End:
19,754,476 bp from pter
Size:
14,192 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: GMIP_HUMAN, Q9P107 (See protein sequence)
Recommended Name: GEM-interacting protein  
Size: 970 amino acids; 106683 Da
Subunit: Interacts with GEM through its N-terminal
1 PDB 3D structure from and Proteopedia for GMIP:
3QWE (3D)    
Secondary accessions: A0AVN9

Explore the universe of human proteins at neXtProt for GMIP: NX_Q9P107

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9P107

  • GMIP Protein expression data from MOPED and PaxDb:    About this image 
    GMIP Protein Expression
    REFSEQ proteins: NP_057657.2  
    ENSEMBL proteins: 
     ENSP00000203556   ENSP00000467054   ENSP00000465108   ENSP00000468662   ENSP00000466045  
     ENSP00000467946   ENSP00000397075  
    Reactome Protein details: Q9P107
    Human Recombinant Protein Products for GMIP: 
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    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for GMIP

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular IC12093360
    GO:0005829cytosol TAS--

    GMIP for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for GMIP


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    GMIP for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR008936 Rho_GTPase_activation_prot
     IPR002219 Prot_Kinase_C-like_PE/DAG-bd
     IPR000198 RhoGAP_dom

    Graphical View of Domain Structure for InterPro Entry Q9P107

    ProtoNet protein and cluster: Q9P107

    1 Blocks protein family: IPB000198 RhoGAP domain

    UniProtKB/Swiss-Prot: GMIP_HUMAN, Q9P107
    Similarity: Contains 1 phorbol-ester/DAG-type zinc finger
    Similarity: Contains 1 Rho-GAP domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GMIP_HUMAN, Q9P107
    Function: Stimulates, in vitro and in vivo, the GTPase activity of RhoA

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005100Rho GTPase activator activity IDA12093360
    GO:0005515protein binding IPI12093360
    GO:0046872metal ion binding IEA--
         
    GMIP for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for GMIP 

    miRNA
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    OriGene 3'-UTR Clone: GMIP
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GMIP
    8 QIAGEN miScript miRNA Assays for microRNAs that regulate GMIP:
    hsa-miR-562 hsa-miR-548p hsa-miR-125a-5p hsa-miR-650 hsa-miR-504 hsa-miR-125b hsa-miR-3612 hsa-miR-4319
    SwitchGear 3'UTR luciferase reporter plasmidGMIP 3' UTR sequence
    Inhib. RNA
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    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GMIP (see all 7)
    OriGene shRNA RFP: GMIP
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    Sirion Biotech Custom design and validation of potent shRNA sequences against GMIP 

    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of GMIP 
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    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GMIP 

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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GMIP


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Cell death signalling via NRAGE, NRIF and NADE
    Signaling by Rho GTPases0.25
    Rho GTPase cycle0.25
    2Signaling by GPCR
    Signal Transduction0.56

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    3        Reactome Pathways for GMIP
        Signaling by Rho GTPases
    Signal Transduction
    Rho GTPase cycle



    GMIP for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for GMIP

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/37 Interacting proteins for GMIP (Q9P1073 ENSP000002035564) via UniProtKB, MINT, STRING, and/or I2D (see all 37)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RHOAP615863, ENSP000004001754I2D: score=1 STRING: ENSP00000400175
    GEMP550403, ENSP000002975964I2D: score=2 STRING: ENSP00000297596
    ARHGAP4ENSP000002037864STRING: ENSP00000203786
    ARHGDIAENSP000002693214STRING: ENSP00000269321
    ARHGEF18ENSP000003529954STRING: ENSP00000352995
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007264small GTPase mediated signal transduction TAS--
    GO:0032321positive regulation of Rho GTPase activity IDA12093360
    GO:0034259negative regulation of Rho GTPase activity IDA12093360
    GO:0035556intracellular signal transduction IDA12093360
    GO:0051056regulation of small GTPase mediated signal transduction TAS--

    GMIP for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GMIP

    10/843 HMDB Compounds for GMIP (see all 843)    About this table
    CompoundSynonyms CAS #PubMed Ids
    DG(14:0/14:0/0:0)DAG(14:0/14:0) (see all 9)----
    DG(14:0/14:1(9Z)/0:0)DAG(14:0/14:1) (see all 15)----
    DG(14:0/15:0/0:0)Diacylglycerol(29:0) (see all 9)----
    DG(14:0/16:0/0:0)DAG(30:0) (see all 9)----
    DG(14:0/16:1(9Z)/0:0)DG(30:1) (see all 15)----
    DG(14:0/18:0/0:0)DG(14:0/18:0) (see all 9)----
    DG(14:0/18:1(11Z)/0:0)Diacylglycerol (see all 15)----
    DG(14:0/18:1(9Z)/0:0)1-myristoyl-2-oleoyl-sn-glycerol (see all 15)----
    DG(14:0/18:2(9Z,12Z)/0:0)DAG(14:0/18:2n6) (see all 15)----
    DG(14:0/18:3(6Z,9Z,12Z)/0:0)Diacylglycerol(14:0/18:3n6) (see all 16)----
    Search CenterWatch for drugs/clinical trials and news about GMIP 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GMIP gene: 
    NM_016573.2  

    Unigene Cluster for GMIP:

    GEM interacting protein
    Hs.49427  [show with all ESTs]
    Unigene Representative Sequence: NM_016573
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000203556(uc002nnd.3 uc010xrb.2 uc010xrc.2) ENST00000587238
    ENST00000586269 ENST00000587713 ENST00000593186 ENST00000588171 ENST00000591047
    ENST00000587205 ENST00000445806

    miRNA
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    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GMIP
    8 QIAGEN miScript miRNA Assays for microRNAs that regulate GMIP:
    hsa-miR-562 hsa-miR-548p hsa-miR-125a-5p hsa-miR-650 hsa-miR-504 hsa-miR-125b hsa-miR-3612 hsa-miR-4319
    SwitchGear 3'UTR luciferase reporter plasmidGMIP 3' UTR sequence
    Inhib. RNA
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    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GMIP (see all 7)
    OriGene shRNA RFP: GMIP
    OriGene siRNA: GMIP
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GMIP
    Sirion Biotech Custom design and validation of potent shRNA sequences against GMIP 
    Clone
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    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GMIP
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    GenScript: all cDNA clones in your preferred vector: GMIP (NM_016573)
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GMIP
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GMIP

    Additional cDNA sequence: 

    AF086104.1 AF132541.1 AK297220.1 BC032057.1 BC126436.1 BC144142.1 

    8 DOTS entries:

    DT.109981  DT.100778591  DT.95174766  DT.121492657  DT.97821350  DT.100778590  DT.121492574  DT.100743949 

    24/150 AceView cDNA sequences (see all 150):

    AI273366 AA554534 BM695857 AI078685 AI498915 BX362896 AI202027 AI650669 
    AW014008 CR595802 BM666941 BM919964 BI912857 BX441041 BX645167 AI818801 
    BM714156 N68010 BE674903 AI400341 AL534214 AI914467 AI818800 AI348210 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for GMIP (see all 6)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22
    SP1:                                                                                                                                                
    SP2:                                                                                                                                                
    SP3:                                                                                                                                                
    SP4:                                                                                      -                                                         
    SP5:                                                                                                                                                


    ECgene alternative splicing isoforms for GMIP

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GMIP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CTGGTGGTGC
    GMIP Expression
    About this image
    See GMIP Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GMIP

    SOURCE GeneReport for Unigene cluster: Hs.49427
        SABiosciences Custom PCR Arrays for GMIP

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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GMIP
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GMIP

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for GMIP gene from 4/20 species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves GMIP1 GEM interacting protein 58.35(n)
    51.63(a)
      426010  XM_423689.3  XP_423689.3 
    lizard
    (Anolis carolinensis)
    Reptilia GMIP6
    --
    51(a)
    1 ↔ 1
    GL343198.1(3940861-3984191)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5658011 GEM-interacting protein-like 53.08(n)
    44.15(a)
      565801  XM_689070.4  XP_694162.4 
    worm
    (Caenorhabditis elegans)
    Secernentea rga-56
    tag-3416
    Protein RGA-5, isoform b
    Temporarily Assigned Gene name family member (tag-...
    5(a)
    17(a)
    possible ortholog
    1 ↔ many
    IV(13827861-13844953)
    II(7912715-7928604)


    ENSEMBL Gene Tree for GMIP (if available)
    TreeFam Gene Tree for GMIP (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GMIP gene
    HMHA12  ARHGAP212  ARHGAP272  CHN22  ARHGAP102  ARHGAP232  ARHGAP92  ARHGAP292  
    ARHGAP262  CHN12  ARHGAP152  ARHGAP122  OPHN12  ARHGAP422  
    6 SIMAP similar genes for GMIP using alignment to 6 protein entries:     GMIP_HUMAN (see all proteins):
    ARHGAP29    ARHGAP21    HMHA1    ARHGAP12    CHN2    ARHGAP8

    GMIP for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/286 NCBI SNPs in GMIP are shown (see all 286    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2019579951,2
    C--19741059(+) CACACC/TGCCCC 2 S G mis10--------
    rs349605561,2
    C,F--19741070(+) GGGGAT/AACTTC 2 /Y /F mis13Minor allele frequency- A:0.01NA WA 3636
    rs1852098281,2
    C--19741131(+) CTCTGA/GGCCTT 2 P S mis10--------
    rs1117212901,2
    C--19741160(+) GGGTGT/GGTGGT 1 -- int11Minor allele frequency- G:0.33CSA 3
    rs2013782191,2
    --19741176(+) CAGAGC/TACCTC 1 -- int10--------
    rs1998793531,2
    --19741251(+) CCAGAA/GCTCCT 1 -- int10--------
    rs1388163761,2
    C,F--19741292(+) TCCCCC/GATCTT 2 R G mis12Minor allele frequency- G:0.01NA EU 5873
    rs355409981,2
    C,F,H--19741311(+) TCAGCC/TACGTC 2 V syn15Minor allele frequency- T:0.00NA NS 4726
    rs1814843641,2
    C--19741340(+) TGGAGC/TTGGAA 2 T A mis10--------
    rs750034421,2
    --19741635(+) CCTATG/ACACAG 1 -- int11Minor allele frequency- A:0.01NA 120

    HapMap Linkage Disequilibrium report for GMIP (19740285 - 19754476 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for GMIP: --
    Human Gene Mutation Database (HGMD): GMIP

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    GMIP for disorders           About GeneDecksing

    OMIM gene information: 609694    OMIM disorders: --

    3 diseases for GMIP:    About MalaCards
    major depressive disorder    systemic lupus erythematosus    lupus erythematosus

    Genetic Association Database (GAD): GMIP
    Human Genome Epidemiology (HuGE) Navigator: GMIP (5 documents)

    Export disorders for GMIP gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GMIP gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with GMIP)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The Gem interacting protein (GMIP) gene is associated with major depressive disorder. (PubMed id 16086184)1, 3, 4, 9 Tadokoro K....Kunugi H. (2005)
    2. A novel Rho GTPase-activating-protein interacts with Gem, a member of the Ras superfamily of GTPases. (PubMed id 12093360)1, 2, 3 Aresta S.... de Gunzburg J. (2002)
    3. Vesicular trafficking through cortical actin during ex ocytosis is regulated by the Rab27a effector JFC1/Slp1 and the RhoA-GTPase-activ ating protein Gem-interacting protein. (PubMed id 22438581)1 Johnson J.L....Catz S.D. (2012)
    4. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    5. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    7. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    8. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    9. Poor replication of candidate genes for major depress ive disorder using genome-wide association data. (PubMed id 20351714)1 Bosker F.J....Nolen W.A. (2010)
    10. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1 Bailey S.D....Anand S. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 51291 HGNC: 24852 AceView: GMIP Ensembl:ENSG00000089639 euGenes: HUgn51291
    ECgene: GMIP H-InvDB: GMIP

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GMIP Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for GMIP gene:
    Search GeneIP for patents involving GMIP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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