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Aliases for GMCL2 Gene

Subcategory (RNA class) for GMCL2 Gene


Aliases for GMCL2 Gene

  • Germ Cell-Less, Spermatogenesis Associated 2 2 3
  • Germ Cell-Less, Spermatogenesis Associated 1 Pseudogene 1 2 5
  • Germ Cell-Less Homolog 1 (Drosophila) Pseudogene 1 2
  • Putative Germ Cell-Less Protein-Like 1-Like 3
  • Germ Cell-Less Homolog 1 (Drosophila)-Like 2
  • Germ Cell-Less Related 3
  • GMCL1P1 5
  • GMCL1L 3
  • GCL 3

External Ids for GMCL2 Gene

ORGUL Members for GMCL2 Gene

Previous HGNC Symbols for GMCL2 Gene

  • GMCL1L
  • GMCL1P1

Summaries for GMCL2 Gene

Entrez Gene Summary for GMCL2 Gene

  • This locus shares a high degree of identity with the multi-exon germ cell-less gene on chromosome 2. Despite its single-exon nature, this chromosome 5 locus contains an open reading frame that could putatively encode a full-length germ cell-less related protein. [provided by RefSeq, Jul 2008]

GeneCards Summary for GMCL2 Gene

GMCL2 (Germ Cell-Less, Spermatogenesis Associated 2) is a Protein Coding gene, and is affiliated with the lncRNA class.

Additional gene information for GMCL2 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GMCL2 Gene

Genomics for GMCL2 Gene

GeneHancer (GH) Regulatory Elements for GMCL2 Gene

Promoters and enhancers for GMCL2 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH05I178187 Enhancer 0.3 Ensembl 550.8 +0.1 131 0.2 ZBTB33 GMCL2 PHYKPL RMND5B LOC645853
GH05I178181 Enhancer 0.8 ENCODE 0.8 +4.9 4929 1 ARNT TCF12 EGR1 CREM CEBPB NCOA1 ZEB2 ATF4 NFIC KLF16 FAM153C GMCL2 LOC645853
GH05I178179 Enhancer 0.7 FANTOM5 ENCODE 0.4 +6.9 6873 1.9 SP1 USF1 POLR2A MAX POU5F1 GMCL2 LOC645853
GH05I178201 Enhancer 0.5 dbSUPER 0.4 -14.7 -14748 0.5 POLR2A HLF REST ZNF600 RARA HNRNPAB GMCL2
GH05I178177 Enhancer 0.4 ENCODE 0.4 +9.8 9751 1 CTCF ZBTB33 GMCL2 LOC645853
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around GMCL2 on UCSC Golden Path with GeneCards custom track

Genomic Locations for GMCL2 Gene

Genomic Locations for GMCL2 Gene
2,923 bases
Minus strand

Genomic View for GMCL2 Gene

Genes around GMCL2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GMCL2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GMCL2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GMCL2 Gene

Proteins for GMCL2 Gene

Post-translational modifications for GMCL2 Gene

No Post-translational modifications

Other Protein References for GMCL2 Gene

REFSEQ proteins:

No data available for DME Specific Peptides for GMCL2 Gene

Domains & Families for GMCL2 Gene

Suggested Antigen Peptide Sequences for GMCL2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains and UniProtKB/Swiss-Prot for GMCL2 Gene

Function for GMCL2 Gene

Phenotypes From GWAS Catalog for GMCL2 Gene

Gene Ontology (GO) - Molecular Function for GMCL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with GMCL2: view

Animal Model Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GMCL2 Gene

Localization for GMCL2 Gene

Gene Ontology (GO) - Cellular Components for GMCL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000151 ubiquitin ligase complex IBA --
GO:0005634 nucleus IBA --
GO:0016363 nuclear matrix IEA --
genes like me logo Genes that share ontologies with GMCL2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for GMCL2 Gene

Pathways & Interactions for GMCL2 Gene

SuperPathways for GMCL2 Gene

No Data Available

Interacting Proteins for GMCL2 Gene

Gene Ontology (GO) - Biological Process for GMCL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007275 multicellular organism development IEA --
GO:0007283 spermatogenesis IEA --
GO:0016567 protein ubiquitination IEA --
GO:0030154 cell differentiation IEA --
genes like me logo Genes that share ontologies with GMCL2: view

No data available for Pathways by source and SIGNOR curated interactions for GMCL2 Gene

Drugs & Compounds for GMCL2 Gene

No Compound Related Data Available

Transcripts for GMCL2 Gene

mRNA/cDNA for GMCL2 Gene

(2) REFSEQ mRNAs :
(22) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for GMCL2 Gene

No ASD Table

Relevant External Links for GMCL2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for GMCL2 Gene

NURSA nuclear receptor signaling pathways regulating expression of GMCL2 Gene:

No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for GMCL2 Gene

Orthologs for GMCL2 Gene

Evolution for GMCL2 Gene

Gene Tree for GMCL2 (if available)
Gene Tree for GMCL2 (if available)

No data available for Orthologs for GMCL2 Gene

Paralogs for GMCL2 Gene

No data available for Paralogs for GMCL2 Gene

Variants for GMCL2 Gene

Sequence variations from dbSNP and Humsavar for GMCL2 Gene

SNP ID Clin Chr 05 pos Variation AA Info Type
VAR_035924 A colorectal cancer sample p.Val275Ala
rs1000973872 -- 178,188,096(-) G/A upstream_transcript_variant
rs1001691362 -- 178,188,854(-) T/A upstream_transcript_variant
rs1002142223 -- 178,188,577(-) G/T upstream_transcript_variant
rs1002716976 -- 178,187,366(-) G/A non_coding_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for GMCL2 Gene

Variant ID Type Subtype PubMed ID
dgv5844n100 CNV gain 25217958
nsv1017664 CNV gain 25217958
nsv1019404 CNV gain 25217958
nsv1120062 OTHER inversion 24896259

Additional Variant Information for GMCL2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for GMCL2 Gene

Disorders for GMCL2 Gene

Additional Disease Information for GMCL2

No disorders were found for GMCL2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GMCL2 Gene

Publications for GMCL2 Gene

  1. Emergence of young human genes after a burst of retroposition in primates. (PMID: 16201836) Marques AC … Kaessmann H (PLoS biology 2005) 2 3 58
  2. Novel Cul3 binding proteins function to remodel E3 ligase complexes. (PMID: 25011449) Wimuttisuk W … Singer JD (BMC cell biology 2014) 3 58
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T … Vidal M (Cell 2014) 3 58
  4. A genome-wide association study suggests contrasting associations in ACPA-positive versus ACPA-negative rheumatoid arthritis. (PMID: 21156761) Padyukov L … Epidemiological Investigation of Rheumatoid Arthritis (EIRA) study group (Annals of the rheumatic diseases 2011) 3 58
  5. Next-generation sequencing to generate interactome datasets. (PMID: 21516116) Yu H … Vidal M (Nature methods 2011) 3 58

Products for GMCL2 Gene

Sources for GMCL2 Gene

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