Aliases for GLYR1 Gene
External Ids for GLYR1 Gene
Previous GeneCards Identifiers for GLYR1 Gene
GeneCards Summary for GLYR1 Gene
GLYR1 (Glyoxylate Reductase 1 Homolog) is a Protein Coding gene. GO annotations related to this gene include methylated histone binding and phosphogluconate dehydrogenase (decarboxylating) activity. An important paralog of this gene is HIBADH.
UniProtKB/Swiss-Prot for GLYR1 Gene
May have oxidoreductase activity. Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling. Indirectly promotes phosphorylation of MAPK14 and activation of ATF2. The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6. Recruited on chromatin, recognizes and binds trimethylated Lys-36 of histone H3 (H3K36me3).