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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

GLYAT Gene

protein-coding GIFtS: 59
GCID: GC11M058476

glycine-N-acyltransferase

Explore 12 diseases affiliated with
GLYAT via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Glycine-N-Acyltransferase¹		Glycine N-Benzoyltransferase² ³
ACGNAT¹ ² ³ ⁵		AAc² ³
GAT¹ ² ³		HRP-1(CLP)² ³
CAT² ³ ⁵		EC 2.3.1.13³ ⁸
Acyl-CoA:Glycine N-Acyltransferase² ³		Aralkyl-CoA N-Acyltransferase²
Aralkyl Acyl-CoA N-Acyltransferase² ³		Glycine N-Acyltransferase²
Aralkyl Acyl-CoA:Amino Acid N-Acyltransferase² ³		EC 2.3.1.71³
Benzoyl-Coenzyme A:Glycine N-Acyltransferase² ³

External Ids:	HGNC: 13734¹	Entrez Gene: 10249²	Ensembl: ENSG00000149124⁷	OMIM: 607424⁵	UniProtKB: Q6IB77³

Export aliases for GLYAT gene to outside databases

Previous GC identifers: GC11M060871 GC11M059990 GC11M058727 GC11M058252 GC11M058251 GC11M058232 GC11M054824

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GLYAT:

The glycine-N-acyltransferase protein conjugates glycine with acyl-CoA substrates in the mitochondria. The protein is

thought to be important in the detoxification of endogenous and xenobiotic acyl-CoA's. Two transcript variants

encoding different isoforms have been found for this gene. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: GLYAT_HUMAN, Q6IB77

Function: Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine,

although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a

preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or

salicylic acid, and endogenous organic acids, such as isovaleric acid

Gene Wiki entry for GLYAT

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000011.9 NC_018922.1 NT_167190.1

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the GLYAT gene promoter:
HOXA9B RP58 p53 POU6F1 (c2) Tal-1beta E47 ARP-1 Meis-1a Meis-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): GLYAT promoter sequence

Search SABiosciences Chromatin IP Primers for GLYAT

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GLYAT

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q12.1 Ensembl cytogenetic band: 11q12.1 HGNC cytogenetic band: 11q12.1

GLYAT Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GLYAT gene location

GeneLoc information about chromosome 11 GeneLoc Exon Structure

GeneLoc location for GC11M058476: view genomic region (about GC identifiers)

Start:	58,407,899 bp from pter	End:	58,499,447 bp from pter
Size:	91,549 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: GLYAT_HUMAN, Q6IB77 (See protein sequence)

Recommended Name: Glycine N-acyltransferase

Size: 296 amino acids; 33924 Da

Subcellular location: Mitochondrion

Sequence caution: Sequence=AAB81453.1; Type=Erroneous initiation; Note=Translation N-terminally extended;

Secondary accessions: O14833 Q96QK7

Alternative splicing: 2 isoforms: Q6IB77-1 Q6IB77-2

Explore the universe of human proteins at neXtProt for GLYAT: NX_Q6IB77

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q6IB77

4 DME Specific Peptides for GLYAT (Q6IB77)

QMLQMLE

WHFGGNE

CLLGPEGTP

INWKQHLQIQSSQ

GLYAT Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_005829.3 NP_964011.2

ENSEMBL proteins:

ENSP00000468512 ENSP00000340200 ENSP00000431688 ENSP00000278400

Reactome Protein details: Q6IB77
Human Recombinant Protein Products for GLYAT:

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	Uscn Proteins for GLYAT

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005739	mitochondrion	ISS	--
GO:0005759	mitochondrial matrix	TAS	--

GLYAT for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

GLYAT for domains About GeneDecksing

4 InterPro domains/families:

IPR016181 Acyl_CoA_acyltransferase

IPR015938 Glycine_N-acyltransferase_N

IPR010313 Glycine_N-acyltransferase

IPR013652 Glycine_N-acyltransferase_C

Graphical View of Domain Structure for InterPro Entry Q6IB77

ProtoNet protein and cluster: Q6IB77

UniProtKB/Swiss-Prot: GLYAT_HUMAN, Q6IB77

Similarity: Belongs to the glycine N-acyltransferase family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: GLYAT_HUMAN, Q6IB77

Function: Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine,

although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a

preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or

salicylic acid, and endogenous organic acids, such as isovaleric acid

Catalytic activity: Acyl-CoA + glycine = CoA + N-acylglycine

Catalytic activity: Benzoyl-CoA + glycine = CoA + hippurate

Biophysicochemical properties: Kinetic parameters: KM=57.9 mM for benzoyl-CoA; KM=83.7 mM for salicyl-CoA; KM=124 mM

for isovaleryl-CoA; KM=198 mM for octanoyl-CoA; Vmax=17.1 umol/min/mg enzyme with benzoyl-CoA as substrate; Vmax=10.1

umol/min/mg enzyme with salicyl-CoA as substrate; Vmax=7.64 umol/min/mg enzyme with isovaleryl-CoA as substrate;

Vmax=3.3 umol/min/mg enzyme with octanoyl-CoA as substrate;

Enzyme Numbers (IUBMB): EC 2.3.1.13¹ ² EC 2.3.1.71¹

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016746	transferase activity, transferring acyl groups	TAS	9202629
GO:0047961	glycine N-acyltransferase activity	IEA	--
GO:0047962	glycine N-benzoyltransferase activity	ISS	--

GLYAT for ontologies About GeneDecksing

Phenotypes:
2 GenomeRNAi human phenotypes for GLYAT:

Decreased Wnt reporter activit

Increased number of cells in m

Animal Models:

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GLYAT

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Amino Acid conjugation

	Conjugation of carboxylic acids	1.00			Conjugation of benzoate with glycine	1.00
	Amino Acid conjugation	1.00			Conjugation of salicylate with glycine	0.67

Biological oxidations

	Biological oxidations	1.00			metapathway biotransformation	0.41
	Phase II conjugation	0.52

Metabolism

Metabolism

1.00

amino acid conjugation of benzoic acid

amino acid conjugation of benzoic acid

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

2 BioSystems Pathways for GLYAT

	amino acid conjugation of benzoic acid
	metapathway biotransformation

5/7 Reactome Pathways for GLYAT (see all 7)

	Conjugation of carboxylic acids
	Conjugation of benzoate with glycine
	Metabolism
	Biological oxidations
	Amino Acid conjugation

GLYAT for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for GLYAT

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

5/8 Interacting proteins for GLYAT (Q6IB77^{2, 3} ENSP00000340200⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 8)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PTN	P21246²^,³, ENSP00000341170⁴	MINT-63081 I2D: score=5 STRING: ENSP00000341170
GPRASP1	Q5JY77²^,³	MINT-63082 I2D: score=4
RBM48	Q5RL73³	I2D: score=4
MDFI	Q99750³	I2D: score=1
VOPP1	Q96AW1³	I2D: score=1

About this table

Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006544	glycine metabolic process	ISS	--
GO:0006637	acyl-CoA metabolic process	TAS	7802672
GO:0006805	xenobiotic metabolic process	TAS	--
GO:0009636	response to toxin	IEA	--
GO:0032787	monocarboxylic acid metabolic process	ISS	--

GLYAT for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

GLYAT for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for GLYAT

10/86 HMDB Compounds for GLYAT (see all 86) About this table

Compound	Synonyms	CAS #	PubMed Ids
Isovalerylsarcosine	N-Isovalerylsarcosine	88127-29-1	6197208
(2E)-Decenoyl-CoA	(E)-S-2-decenoate Coenzyme A (see all 15)	10018-95-8	--
(2E)-Dodecenoyl-CoA	2-trans-Dodecenoyl-Coenzyme A (see all 4)	1066-12-2	--
(2E)-Hexadecenoyl-CoA	trans-2-Hexadecenoyl-CoA (see all 4)	4460-95-1	--
(2E)-Octenoyl-CoA	(E)-S-2-octenoate Coenzyme A (see all 16)	10018-94-7	--
(2E)-Tetradecenoyl-CoA	(2E)-Tetradecenoyl-Coenzyme A (see all 8)	38795-33-4	--
2-Furoylglycine	2-Furoylglycine (see all 11)	5657-19-2	--
2-Methylbutyryl-CoA	2-methylbutanoyl-CoA (see all 11)	6712-02-3	--
2-Methylbutyrylglycine	(2-methyl-butyrylamino)-acetate (see all 7)	52320-67-9	--
2-Methylhexanoyl-CoA	2-Methylhexanoyl-CoEnzyme A (see all 5)	--	--

1 DrugBank Compound for GLYAT About this table

Compound	Synonyms	CAS #	Type	Actions	PubMed Ids
Glycine	2-Aminoacetic acid (see all 4)	56-40-6	target	--	17146584 17143481

2 Novoseek chemical compound relationships for GLYAT gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
benzoyl-coa	74.7	3	10630424 (2), 7802672 (1)
estrogen	0	4	1779966 (1), 7517003 (1)

Search CenterWatch for drugs/clinical trials and news about GLYAT

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for GLYAT gene (2 alternative transcripts):

NM_005838.3 NM_201648.2

Unigene Cluster for GLYAT:

Glycine-N-acyltransferase

Hs.145384 [show with all ESTs]

Unigene Representative Sequence: NM_201648

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000586098 ENST00000344743(uc001nnb.3) ENST00000529732 ENST00000278400(uc001nnc.3)

ENST00000531084

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Additional cDNA sequence:

AB665285.1 AF023466.1 BC009785.1 CR456927.1

4 DOTS entries:

DT.313485 DT.92428156 DT.92428155 DT.75131930

24/87 AceView cDNA sequences (see all 87):

AW024233 NM_201648 BX091574 AW237450 AI244067 AI522080 AI521852 AI991367

NM_005838 AI431833 AI478457 AI253073 BF104782 CR456927 BG433395 AI248650

AI793201 CB161978 BG566326 AB013093 AV645422 BG432065 W89062 BG400428

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for GLYAT About this scheme

ExUns:	1a	·	1b	·	1c	^	2	^	3a	·	3b	^	4	^	5	^	6	^	7a	·	7b
SP1:							-				-
SP2:							-				-
SP3:											-
SP4:							-

ECgene alternative splicing isoforms for GLYAT

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

GLYAT expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

GLYAT expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Posterior foregut-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See GLYAT Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for GLYAT

SOURCE GeneReport for Unigene cluster: Hs.145384

UniProtKB/Swiss-Prot: GLYAT_HUMAN, Q6IB77

Tissue specificity: Predominantly expressed in liver (at protein level) and kidney. Down-regulated in hepatocellular

carcinoma and other liver cancers

SABiosciences Expression via Pathway-Focused PCR Array including GLYAT:

Drug Metabolism: Phase II Enzymes in human mouse rat

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for GLYAT gene from 1/7 species (see all 7) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
zebrafish (Danio rerio)	Actinopterygii	si:dkey-76k16.5⁶	si:dkey-76k16.5	27(a)	1 ↔ 1	13(33889503-33892397)

ENSEMBL Gene Tree for GLYAT (if available)
TreeFam Gene Tree for GLYAT (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for GLYAT gene

GLYATL1² GLYATL3² GLYATL2²

5 SIMAP similar genes for GLYAT using alignment to 2 protein entries: GLYAT_HUMAN (see all proteins):

GLYATL1 GATF-C GATF-B GLYATL2 GLYATL3

GLYAT for paralogs About GeneDecksing

2 Pseudogenes.org Pseudogenes for GLYAT
PGOHUM00000242304 PGOHUM00000242742

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 11 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs139987704^1,2		--	58475754(+)	`CAGCAA/CGAAAC`	1	--	int¹		0	--	--	--	--
rs77696594^1,2	F	--	58475820(+)	`GAAAGA/TTTATC`	1	--	int¹		1		EA	120
rs59373194^1,2	C	--	58475844(+)	`CTCAAC/TTGACT`	1	--	int¹		3		WA CSA	121
rs190872329^1,2		--	58476038(+)	`TTGTGA/CCTGAA`	1	--	int¹		0	--	--	--	--
rs79722829^1,2	C,F	--	58476185(+)	`AGACAC/TCAAAT`	1	--	int¹		1		EA	120
rs182586510^1,2		--	58476186(+)	`GACACA/CAAATC`	1	--	int¹		0	--	--	--	--
rs115909531^1,2	F	--	58476212(+)	`TTTAGA/GCTTCC`	1	--	int¹		1		WA	118
rs143895466^1,2		--	58476384(+)	`GGTGTC/TCATGC`	1	--	ut3¹		0	--	--	--	--
rs77337461^1,2	F	--	58476455(+)	`GTGCTC/TCCACC`	1	--	ut3¹		1		NA	120
rs114299324^1,2	F	--	58476544(+)	`GTATAC/TAGTCA`	1	--	ut3¹		1		WA	118

HapMap Linkage Disequilibrium report for GLYAT (58407899 - 58499447 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for GLYAT
1 CNV: 34989

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

GLYAT for disorders           About GeneDecksing

OMIM gene information: 607424    OMIM disorders: --

12 diseases for GLYAT:    About MalaCards

osteogenesis imperfecta type i osteogenesis imperfecta bullous pemphigoid intrahepatic cholangiocarcinoma

cholangiocarcinoma pertussis breast cancer glioblastoma

neuroblastoma immunodeficiency hepatocellular carcinoma carcinoma

1 disease from the University of Copenhagen DISEASES database for GLYAT:

substance-induced psychosis

3 Novoseek disease relationships for GLYAT gene About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
shock	11.2	2	14673135 (1), 9548565 (1)
necrosis	0	2	7891669 (2)
tumors	0	2	7891669 (2)

Human Genome Epidemiology (HuGE) Navigator: GLYAT (3 documents)

Export disorders for GLYAT gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for GLYAT gene, integrated from 9 sources (see all 44):
(articles sorted by number of sources associating them with GLYAT)

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Purification to homogeneity of mitochondrial acyl CoA:glycine N- acyltransferase from human liver. (PubMed id 7802672)^{1, 2, 9} Mawal Y.R. and Qureshi I.A. (1994)
The utilization of alanine, glutamic acid, and serine as amino acid substrates for glycine N-acyltransferase. (PubMed id 10630424)^{1, 2, 9} van der Westhuizen F.H.... Erasmus E. (2000)
Designation of enzyme activity of glycine-N-acyltransferase family genes and depression of glycine-N-acyltransferase in human hepatocellular carcinoma. (PubMed id 22475485)^{1, 2} Matsuo M.... Kishimoto T. (2012)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Developmental profile of mitochondrial glycine N-acyltransferase in human liver. (PubMed id 9202629)^{1, 9} Mawal Y....Qureshi I.A. (1997)
An immunodetection method for the quantitation of human acyl CoA:glycine N-acyltransferase in biological samples. (PubMed id 7833837)^{1, 9} Mawal Y.R. and Qureshi I.A. (1994)
Fatty acid amide biosynthesis: a possible new role for peptidylglycine alpha-amidating enzyme and acyl-coenzyme A: glycine N-acyltransferase. (PubMed id 8660675)^{1, 9} Merkler D.J....Fleming F.F. (1996)
Genetic polymorphisms of glycine N-acyltransferase in Japanese individuals. (PubMed id 19252341)^{1, 9} Yamamoto A....Azuma J. (2009)
Genetic polymorphisms of Glycine N-acyltransferase (G LYAT) in a French Caucasian population. (PubMed id 20925583)¹ Lino Cardenas C.L....Chevalier D. (2010)
Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)¹ Hendrickson S.L....O'Brien S.J. (2010)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Disorders
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 10249	HGNC: 13734	AceView: GLYAT	Ensembl:ENSG00000149124	euGenes: HUgn10249
ECgene: GLYAT	H-InvDB: GLYAT

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for GLYAT	Pharmacogenomics, SNPs, Pathways

Intellectual Property for GLYAT gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for GLYAT gene:
Search GeneIP for patents involving GLYAT

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

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