Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

GLTSCR2 Gene

protein-coding GIFtS: 49
GCID: GC19P048248

glioma tumor suppressor candidate region gene 2

Explore 6 diseases affiliated with
GLTSCR2 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Glioma Tumor Suppressor Candidate Region Gene 2¹ ²
PICT-1¹ ²
P60¹
PICT1²
Glioma Tumor Suppressor Candidate Region Gene 2 Protein²
Protein Interacting With Carboxyl Terminus 1²

External Ids:	HGNC: 4333¹	Entrez Gene: 29997²	Ensembl: ENSG00000105373⁷	OMIM: 605691⁵	UniProtKB: Q9NZM5³

Export aliases for GLTSCR2 gene to outside databases

Previous GC identifers: GC19P048895 GC19P048639 GC19P052924 GC19P052940 GC19P052934 GC19P044676

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Gene Wiki entry for GLTSCR2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000019.9 NC_018930.1 NT_011109.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the GLTSCR2 gene promoter:
E2F-4 E2F-3a E2F-5 NF-1 NF-1/L p53 E2F-2 E2F-1 E2F
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: GLTSCR2 promoter sequence

Search SABiosciences Chromatin IP Primers for GLTSCR2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GLTSCR2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.3 Ensembl cytogenetic band: 19q13.33 HGNC cytogenetic band: 19q13.3

GLTSCR2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GLTSCR2 gene location

GeneLoc information about chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19P048248: view genomic region (about GC identifiers)

Start:	48,248,793 bp from pter	End:	48,260,323 bp from pter
Size:	11,531 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: GSCR2_HUMAN, Q9NZM5 (See protein sequence)

Recommended Name: Glioma tumor suppressor candidate region gene 2 protein

Size: 478 amino acids; 54389 Da

Subunit: Interacts with HSV-1 early proteins ICP22 and ICP0

Subcellular location: Nucleus, nucleolus

Secondary accessions: Q9BTC6 Q9HAX6 Q9NPP1 Q9NPR4 Q9UFI2

Explore the universe of human proteins at neXtProt for GLTSCR2: NX_Q9NZM5

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9NZM5

GLTSCR2 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_056525.2

ENSEMBL proteins:

ENSP00000246802

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate: GLTSCR2 OriGene Custom Protein Services for GLTSCR2
	GenScript Custom Purified and Recombinant Proteins Services for GLTSCR2
	Novus Biologicals GLTSCR2 Proteins Novus Biologicals GLTSCR2 Lysates
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for GLTSCR2

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	NAS	10196275
GO:0005730	nucleolus	IDA	--
GO:0043231	intracellular membrane-bounded organelle	IDA	--

GLTSCR2 for ontologies About GeneDecksing

GLTSCR2 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for GLTSCR2
	GenScript Custom Superior Antibodies Services for GLTSCR2
	Novus Biologicals GLTSCR2 Antibodies
	Search for Antibodies for GLTSCR2 at Abcam
	Uscn Antibodies for GLTSCR2
	Search ThermoFisher Antibodies for GLTSCR2

Assay Products for GLTSCR2:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for GLTSCR2
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for GLTSCR2

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

GLTSCR2 for domains About GeneDecksing

2 InterPro domains/families:

IPR011687 P60-like

IPR011211 Gltscr2

Graphical View of Domain Structure for InterPro Entry Q9NZM5

ProtoNet protein and cluster: Q9NZM5

1 Blocks protein family: IPB011687 P60-like

UniProtKB/Swiss-Prot: GSCR2_HUMAN, Q9NZM5

Similarity: Belongs to the GLTSCR2 family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

miRNA Products:		OriGene 3'-UTR Clone: GLTSCR2 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GLTSCR2
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate GLTSCR2
		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GLTSCR2 (see all 7) OriGene shRNA RFP: GLTSCR2 OriGene siRNA: GLTSCR2
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GLTSCR2

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for GLTSCR2

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GLTSCR2 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GLTSCR2 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: GLTSCR2 (NM_015710)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for GLTSCR2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GLTSCR2

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for GLTSCR2
		Search LifeMap BioReagents cell lines for GLTSCR2

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GLTSCR2

Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003674	molecular_function	ND	--

GLTSCR2 for ontologies About GeneDecksing

4 GenomeRNAi human phenotypes for GLTSCR2:

Decreased DCP1a protein expres

Decreased TP53 protein express

Decreased sensitivity to pacli

Decreased viability of wild-ty

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for GLTSCR2

STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

5/17 Interacting proteins for GLTSCR2 (Q9NZM5^{2, 3} ENSP00000246802⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 17)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
HAP1	P54257²^,³	MINT-65664 I2D: score=4
SLX4	Q8IY92³, ENSP00000294008⁴	I2D: score=2 STRING: ENSP00000294008
UIMC1	Q96RL1³, ENSP00000366434⁴	I2D: score=2 STRING: ENSP00000366434
USP45	Q70EL2³, ENSP00000333376⁴	I2D: score=2 STRING: ENSP00000333376
EIF2AK2	P19525³, ENSP00000233057⁴	I2D: score=1 STRING: ENSP00000233057

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008150	biological_process	ND	--

GLTSCR2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for GLTSCR2
Search CenterWatch for drugs/clinical trials and news about GLTSCR2 / GSCR2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for GLTSCR2 gene:

NM_015710.4

Unigene Cluster for GLTSCR2:

Glioma tumor suppressor candidate region gene 2

Hs.421907 [show with all ESTs]

Unigene Representative Sequence: BM541989

1 Ensembl transcript including schematic representation, and UCSC links where relevant:

ENST00000246802(uc002phm.2 uc010elk.1)

miRNA Products:		OriGene 3'-UTR Clone: GLTSCR2 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GLTSCR2
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate GLTSCR2
		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GLTSCR2 (see all 7) OriGene shRNA RFP: GLTSCR2 OriGene siRNA: GLTSCR2
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GLTSCR2

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GLTSCR2 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GLTSCR2 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: GLTSCR2 (NM_015710)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for GLTSCR2
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GLTSCR2

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GLTSCR2 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat GLTSCR2
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GLTSCR2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GLTSCR2

Additional cDNA sequence:

AF161389.1 AF182076.1 AF296124.1 AK225915.1 AK297877.1 AK301117.1 AL359335.1 AL359336.1

AY535000.1 BC004229.2 BC006311.2 BC007248.1 BC010095.2 BC013203.1 BC013235.1 BC013307.1

BC014009.2 BC039869.1 NR_003048.1

24/35 DOTS entries (see all 35):

DT.100856380 DT.95118197 DT.91898118 DT.91776802 DT.100678692 DT.95230703 DT.100810424 DT.100678702

DT.100678696 DT.91776772 DT.100678688 DT.100678677 DT.121467540 DT.100678689 DT.100678693 DT.100039484

DT.121467626 DT.450892 DT.95100684 DT.100039481 DT.91776770 DT.100697359 DT.95230588 DT.100678694

24/1598 AceView cDNA sequences (see all 1598):

BU849205 BQ706682 BQ889677 BQ685691 BM810803 AA577022 BF725531 BU507727

AI383863 BU528675 CD107942 BM753025 BE731458 BU151613 BQ436103 BI962904

BM772345 AA954515 AL546312 CR605735 CR591907 BX351161 BQ064288 BQ638109

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

GLTSCR2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image
See GLTSCR2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for GLTSCR2

SOURCE GeneReport for Unigene cluster: Hs.421907

UniProtKB/Swiss-Prot: GSCR2_HUMAN, Q9NZM5

Tissue specificity: Expressed at high levels in heart and pancreas, moderate levels in placenta, liver, skeletal

muscle, and kidney, and low levels in brain and lung

SABiosciences Custom PCR Arrays for GLTSCR2

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GLTSCR2 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat GLTSCR2
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GLTSCR2
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GLTSCR2

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GLTSCR2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for GLTSCR2 gene from 9/28 species (see all 28) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Gltscr2^{1 , 5}	glioma tumor suppressor candidate region gene 2^{1, 5}	81.87(n)¹ 82.43(a)¹		7 (8.64 cM)⁵ 68077¹ NM_133831.3¹ NP_598592.2¹ 15937838⁵
lizard (Anolis carolinensis)	Reptilia	-- --	--	57(a) 37(a)	many → 1 many → 1	GL344061.1(56447-66974) AAWZ02038532(4001-10535)
tropical clawed frog (Xenopus tropicalis)	Amphibia	Str.527²	Transcribed sequence with weak similarity to protein more	76.39(n)		CF151859.1
zebrafish (Danio rerio)	Actinopterygii	zgc:123178¹	zgc:123178	54.33(n) 52.47(a)		322404 NM_001079946.1 NP_001073415.1
fruit fly (Drosophila melanogaster)	Insecta	CG1785¹	CG1785	46.08(n) 32.03(a)		31810 NM_132274.2 NP_572502.1
worm (Caenorhabditis elegans)	Secernentea	CELE_Y39B6A.33¹	Protein Y39B6A.33	41.96(n) 31.98(a)		180246 NM_171574.3 NP_741664.1
baker's yeast (Saccharomyces cerevisiae)	Saccharomycetes	NOP53¹	Nop53p	36.29(n) 26.81(a)		855957 NP_015179.1
thale cress (Arabidopsis thaliana)	eudicotyledons	AT2G40430¹	hypothetical protein	38.93(n) 25.95(a)		818636 NM_001202792.1 NP_001189721.1
rice (Oryza sativa)	Liliopsida	--	glioma tumor suppressor candidate region gene 2 pr...	24(a)	1 ↔ 1	5(2541317-2545952)

ENSEMBL Gene Tree for GLTSCR2 (if available)
TreeFam Gene Tree for GLTSCR2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for GLTSCR2 gene

1 SIMAP similar gene for GLTSCR2 using alignment to 6 protein entries: GSCR2_HUMAN (see all proteins):

FLJ00085

GLTSCR2 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for GLTSCR2
PGOHUM00000247282

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 19 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs189514288^1,2		--	48246915(+)	`GCGCAC/TCGTGC`	1	--	us2k¹		0	--	--	--	--
rs75405966^1,2	C,F,	--	48247015(+)	`GTTTCG/TCGGCT`	1	--	us2k¹		2		WA EA	238
rs1974817^1,2	C,F,O,A,H,	--	48247045(-)	`TTTTCT/GGAGCG`	1	--	us2k¹ tfbs³		15		NS NA EA WA	1074
rs58079237^1,2	C,	--	48247076(+)	`AAATCC/TCTGCC`	1	--	us2k¹		2		WA	120
rs181932916^1,2		--	48247081(+)	`CCTGCC/TCAGGT`	1	--	us2k¹		0	--	--	--	--
rs2334290^1,2	C,F,O,A,H,	--	48247090(+)	`GTGATT/CCGGCG`	1	--	us2k¹		17		EA NA NS WA	970
rs186181111^1,2		--	48247106(+)	`GTCTCG/TGGGCT`	1	--	us2k¹		0	--	--	--	--
rs147832681^1,2		--	48247138(+)	`TTAGGA/GCCTGT`	1	--	us2k¹		0	--	--	--	--
rs190649670^1,2		--	48247173(+)	`GATCCA/CGTTGA`	1	--	us2k¹		0	--	--	--	--
rs181543938^1,2		--	48247207(+)	`TGTCGC/TCTGCC`	1	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for GLTSCR2 (48248793 - 48260323 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for GLTSCR2: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GLTSCR2

DNA2.0 Custom Variant and Variant Library Synthesis for GLTSCR2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

GLTSCR2 for disorders           About GeneDecksing

OMIM gene information: 605691    OMIM disorders: --

6 diseases for GLTSCR2:    About MalaCards

seborrheic keratosis keratosis herpes simplex kaposi's sarcoma

sarcoma glioblastoma

Export disorders for GLTSCR2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for GLTSCR2 gene, integrated from 9 sources (see all 35):
(articles sorted by number of sources associating them with GLTSCR2)

Utopia: connect your pdf to the dynamic
world of online information

A transcript map of the chromosome 19q-Arm glioma tumor suppressor region. (PubMed id 10708517)^{1, 2, 3} Smith J.S.... Jenkins R.B. (2000)
A novel cellular protein, p60, interacting with both herpes simplex virus 1 regulatory proteins ICP22 and ICP0 is modified in a cell-type- specific manner and is recruited to the nucleus after infection. (PubMed id 10196275)^{1, 2, 9} Bruni R.... Roizman B. (1999)
Critical role of PICT-1, a tumor suppressor candidate, in phosphatidylinositol 3,4,5-trisphosphate signals and tumorigenic transformation. (PubMed id 16971513)^{1, 3, 9} Okahara F....Maehama T. (2006)
The putative tumor suppressor gene GLTSCR2 induces PT EN-modulated cell death. (PubMed id 17657248)^{1, 3, 9} Yim J.H....Park J.H. (2007)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Functional proteomic analysis of human nucleolus. (PubMed id 12429849)^{1, 2} Scherl A.... Diaz J.-J. (2002)
Suppression of putative tumour suppressor gene GLTSCR2 expression in human glioblastomas. (PubMed id 18729076)^{1, 9} Kim Y.J....Park J.H. (2008)
GLTSCR2/PICT-1, a putative tumor suppressor gene prod uct, induces the nucleolar targeting of the Kaposi's sarcoma-associated herpesv irus KS-Bcl-2 protein. (PubMed id 20042497)^{1, 9} Kalt I....Sarid R. (2010)
A census of human soluble protein complexes. (PubMed id 22939629)¹ Havugimana P.C....Emili A. (2012)
Nucleolar localization of GLTSCR2/PICT-1 is mediated b y multiple unique nucleolar localization sequences. (PubMed id 22292050)¹ Kalt I....Sarid R. (2012)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 29997	HGNC: 4333	AceView: GLTSCR2	Ensembl:ENSG00000105373	euGenes: HUgn29997
ECgene: GLTSCR2	H-InvDB: GLTSCR2

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for GLTSCR2	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for GLTSCR2	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for GLTSCR2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for GLTSCR2 gene:
Search GeneIP for patents involving GLTSCR2

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for GLTSCR2
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GLTSCR2		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GLTSCR2
	OriGene Protein Over-expression Lysate for GLTSCR2		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for GLTSCR2		OriGene 3'-UTR Clone for GLTSCR2
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GLTSCR2		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GLTSCR2
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for GLTSCR2		OriGene Custom Protein Services for GLTSCR2
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat GLTSCR2
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GLTSCR2
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GLTSCR2
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GLTSCR2
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GLTSCR2
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GLTSCR2

	GenScript Custom Purified and Recombinant Proteins Services for GLTSCR2		GenScript cDNA clones with any tag delivered in your preferred vector for GLTSCR2
	GenScript Custom Assay Services for GLTSCR2		GenScript Custom Superior Antibodies Services for GLTSCR2
	GenScript Custom overexpressing Cell Line Services for GLTSCR2		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in GLTSCR2 promoter
	Search Chromatin IP Primers for GLTSCR2
	RT² qPCR Primer Assay in human, mouse, rat GLTSCR2
	GNC Network for GLTSCR2
	SABiosciences Custom PCR Arrays for GLTSCR2

Search Tocris compounds for GLTSCR2

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	GLTSCR2 antibodies
	GLTSCR2 proteins
	GLTSCR2 lysates

	Search for Antibodies for GLTSCR2 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for GLTSCR2
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

GLTSCR2 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for GLTSCR2

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GLTSCR2

	Browse SwitchGear 3'UTR luciferase reporter plasmids for GLTSCR2
	SwitchGear Promoter luciferase reporter plasmids for GLTSCR2

Search ThermoFisher Antibodies for GLTSCR2

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GLTSCR2

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes GLTSCR2 gene at Home site.

hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4

Advanced Search

Export list of displayed genes

GLTSCR2 Gene

glioma tumor suppressor candidate region gene 2

Aliases
for GLTSCR2 gene

Summaries
for GLTSCR2 gene

Genomic Views
for GLTSCR2 gene

Proteins
for GLTSCR2 gene

Protein Domains /
Families
for GLTSCR2 gene

Function
for GLTSCR2 gene

Pathways & Interactions
for GLTSCR2 gene

Drugs & Compounds
for GLTSCR2 gene

Transcripts
for GLTSCR2 gene

Expression
for GLTSCR2 gene

Orthologs
for GLTSCR2 gene

Paralogs
for GLTSCR2 gene

Genomic Variants
for GLTSCR2 gene

Disorders / Diseases
for GLTSCR2 gene

Publications
for GLTSCR2 gene

External Searches for GLTSCR2 gene

Genome Databases showing GLTSCR2 gene

Other Databases showing GLTSCR2 gene

Specialized Databases showing GLTSCR2 gene

Intellectual Property
for GLTSCR2 gene

Products
for GLTSCR2 gene

View Random Gene

Advanced Search

Export list of displayed genes

GLTSCR2 Gene

glioma tumor suppressor candidate region gene 2

Aliasesfor GLTSCR2 gene

Summariesfor GLTSCR2 gene

Genomic Viewsfor GLTSCR2 gene

Proteinsfor GLTSCR2 gene

Protein Domains /Familiesfor GLTSCR2 gene

Functionfor GLTSCR2 gene

Pathways & Interactionsfor GLTSCR2 gene

Drugs & Compoundsfor GLTSCR2 gene

Transcriptsfor GLTSCR2 gene

Expression for GLTSCR2 gene

Orthologsfor GLTSCR2 gene

Paralogsfor GLTSCR2 gene

Genomic Variantsfor GLTSCR2 gene

Disorders / Diseasesfor GLTSCR2 gene

Publicationsfor GLTSCR2 gene

External Searches for GLTSCR2 gene

Genome Databases showing GLTSCR2 gene

Other Databases showing GLTSCR2 gene

Specialized Databases showing GLTSCR2 gene

Intellectual Propertyfor GLTSCR2 gene

Productsfor GLTSCR2 gene

View Random Gene

Aliases
for GLTSCR2 gene

Summaries
for GLTSCR2 gene

Genomic Views
for GLTSCR2 gene

Proteins
for GLTSCR2 gene

Protein Domains /
Families
for GLTSCR2 gene

Function
for GLTSCR2 gene

Pathways & Interactions
for GLTSCR2 gene

Drugs & Compounds
for GLTSCR2 gene

Transcripts
for GLTSCR2 gene

Expression
for GLTSCR2 gene

Orthologs
for GLTSCR2 gene

Paralogs
for GLTSCR2 gene

Genomic Variants
for GLTSCR2 gene

Disorders / Diseases
for GLTSCR2 gene

Publications
for GLTSCR2 gene

Intellectual Property
for GLTSCR2 gene

Products
for GLTSCR2 gene