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Aliases for GLTSCR1L Gene

Aliases for GLTSCR1L Gene

  • GLTSCR1 Like 2 3 5
  • KIAA0240 2 3 4
  • Glioma Tumor Suppressor Candidate Region Gene 1 Protein-Like 3 4
  • GLTSCR1-Like Protein 3
  • GLTSCR1-Like 2

External Ids for GLTSCR1L Gene

Previous HGNC Symbols for GLTSCR1L Gene

  • KIAA0240

Previous GeneCards Identifiers for GLTSCR1L Gene

  • GC06P042715
  • GC06P042749
  • GC06P042747

Summaries for GLTSCR1L Gene

GeneCards Summary for GLTSCR1L Gene

GLTSCR1L (GLTSCR1 Like) is a Protein Coding gene. An important paralog of this gene is GLTSCR1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GLTSCR1L Gene

Genomics for GLTSCR1L Gene

Regulatory Elements for GLTSCR1L Gene

Enhancers for GLTSCR1L Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around GLTSCR1L on UCSC Golden Path with GeneCards custom track

Promoters for GLTSCR1L Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around GLTSCR1L on UCSC Golden Path with GeneCards custom track

Genomic Location for GLTSCR1L Gene

Chromosome:
6
Start:
42,746,958 bp from pter
End:
42,868,560 bp from pter
Size:
121,603 bases
Orientation:
Plus strand

Genomic View for GLTSCR1L Gene

Genes around GLTSCR1L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GLTSCR1L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GLTSCR1L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GLTSCR1L Gene

Proteins for GLTSCR1L Gene

  • Protein details for GLTSCR1L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6AI39-GSC1L_HUMAN
    Recommended name:
    GLTSCR1-like protein
    Protein Accession:
    Q6AI39
    Secondary Accessions:
    • A1L3W2
    • Q5TFZ3
    • Q92514

    Protein attributes for GLTSCR1L Gene

    Size:
    1079 amino acids
    Molecular mass:
    115084 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=BAA13246.2; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

neXtProt entry for GLTSCR1L Gene

Post-translational modifications for GLTSCR1L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GLTSCR1L Gene

No data available for DME Specific Peptides for GLTSCR1L Gene

Domains & Families for GLTSCR1L Gene

Protein Domains for GLTSCR1L Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with GLTSCR1L: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for GLTSCR1L Gene

Function for GLTSCR1L Gene

genes like me logo Genes that share phenotypes with GLTSCR1L: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GLTSCR1L Gene

Localization for GLTSCR1L Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for GLTSCR1L Gene

Pathways & Interactions for GLTSCR1L Gene

SuperPathways for GLTSCR1L Gene

No Data Available

Gene Ontology (GO) - Biological Process for GLTSCR1L Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GLTSCR1L Gene

Drugs & Compounds for GLTSCR1L Gene

No Compound Related Data Available

Transcripts for GLTSCR1L Gene

Unigene Clusters for GLTSCR1L Gene

GLTSCR1-like:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for GLTSCR1L Gene

No ASD Table

Relevant External Links for GLTSCR1L Gene

GeneLoc Exon Structure for
GLTSCR1L
ECgene alternative splicing isoforms for
GLTSCR1L

Expression for GLTSCR1L Gene

mRNA expression in normal human tissues for GLTSCR1L Gene

Protein differential expression in normal tissues from HIPED for GLTSCR1L Gene

This gene is overexpressed in Islet of Langerhans (55.1) and CD8 Tcells (7.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for GLTSCR1L Gene



Protein tissue co-expression partners for GLTSCR1L Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of GLTSCR1L Gene:

GLTSCR1L

SOURCE GeneReport for Unigene cluster for GLTSCR1L Gene:

Hs.658033
genes like me logo Genes that share expression patterns with GLTSCR1L: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for GLTSCR1L Gene

Orthologs for GLTSCR1L Gene

This gene was present in the common ancestor of chordates.

Orthologs for GLTSCR1L Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia GLTSCR1L 34
  • 90.93 (n)
  • 92.4 (a)
GLTSCR1L 35
  • 92 (a)
OneToOne
dog
(Canis familiaris)
Mammalia GLTSCR1L 34
  • 92.77 (n)
  • 94.74 (a)
GLTSCR1L 35
  • 92 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gltscr1l 34
  • 85.53 (n)
  • 87.57 (a)
Gltscr1l 16
Gltscr1l 35
  • 87 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia GLTSCR1L 34
  • 99.54 (n)
  • 99.63 (a)
GLTSCR1L 35
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Gltscr1l 34
  • 86.91 (n)
  • 88.61 (a)
oppossum
(Monodelphis domestica)
Mammalia GLTSCR1L 35
  • 83 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia GLTSCR1L 35
  • 77 (a)
OneToOne
chicken
(Gallus gallus)
Aves KIAA0240 34
  • 76.39 (n)
  • 76.68 (a)
GLTSCR1L 35
  • 72 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia GLTSCR1L 35
  • 71 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia gltscr1l 34
  • 61.43 (n)
  • 52.47 (a)
zebrafish
(Danio rerio)
Actinopterygii gltscr1l 34
  • 55.67 (n)
  • 50.09 (a)
gltscr1l 35
  • 37 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 26 (a)
OneToMany
Species where no ortholog for GLTSCR1L was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GLTSCR1L Gene

ENSEMBL:
Gene Tree for GLTSCR1L (if available)
TreeFam:
Gene Tree for GLTSCR1L (if available)

Paralogs for GLTSCR1L Gene

Paralogs for GLTSCR1L Gene

genes like me logo Genes that share paralogs with GLTSCR1L: view

Variants for GLTSCR1L Gene

Sequence variations from dbSNP and Humsavar for GLTSCR1L Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs4711727 -- 42,786,291(+) GGAAA(A/G)TTTTT intron-variant
rs4711728 -- 42,791,932(+) ctatt(C/G)ctcct intron-variant
rs4711730 -- 42,853,157(-) ATTCT(A/C/G/T)CACCC intron-variant
rs4714628 -- 42,804,774(+) ATACA(A/G)TCTAA intron-variant
rs4714629 -- 42,807,739(+) aggcg(A/G)aaaca intron-variant

Structural Variations from Database of Genomic Variants (DGV) for GLTSCR1L Gene

Variant ID Type Subtype PubMed ID
esv2668024 CNV deletion 23128226
esv3576145 CNV gain 25503493
esv3608805 CNV loss 21293372
nsv1017398 CNV gain 25217958
nsv433480 CNV loss 18776910
nsv830650 CNV loss 17160897
nsv830651 CNV loss 17160897
nsv958388 CNV deletion 24416366

Variation tolerance for GLTSCR1L Gene

Residual Variation Intolerance Score: 21% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.30; 53.28% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for GLTSCR1L Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
GLTSCR1L

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GLTSCR1L Gene

Disorders for GLTSCR1L Gene

Relevant External Links for GLTSCR1L

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
GLTSCR1L

No disorders were found for GLTSCR1L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GLTSCR1L Gene

Publications for GLTSCR1L Gene

  1. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3 4 65
  2. Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain. (PMID: 9039502) Nagase T. … Nomura N. (DNA Res. 1996) 3 4 65
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 65
  4. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 65
  5. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H. … Mohammed S. (J. Proteome Res. 2013) 4 65

Products for GLTSCR1L Gene

Sources for GLTSCR1L Gene

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