Free for academic non-profit institutions. Other users need a Commercial license

Aliases for GLT1D1 Gene

Aliases for GLT1D1 Gene

  • Glycosyltransferase 1 Domain Containing 1 2 3 5
  • EC 2.4.-.- 4

External Ids for GLT1D1 Gene

Previous GeneCards Identifiers for GLT1D1 Gene

  • GC12P127863
  • GC12P129337
  • GC12P126322

Summaries for GLT1D1 Gene

GeneCards Summary for GLT1D1 Gene

GLT1D1 (Glycosyltransferase 1 Domain Containing 1) is a Protein Coding gene. GO annotations related to this gene include transferase activity, transferring glycosyl groups.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GLT1D1 Gene

Genomics for GLT1D1 Gene

Regulatory Elements for GLT1D1 Gene

Enhancers for GLT1D1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around GLT1D1 on UCSC Golden Path with GeneCards custom track

Promoters for GLT1D1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Transcription factor binding sites by QIAGEN in the GLT1D1 gene promoter:

Genomic Location for GLT1D1 Gene

128,853,427 bp from pter
128,984,968 bp from pter
131,542 bases
Plus strand

Genomic View for GLT1D1 Gene

Genes around GLT1D1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GLT1D1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GLT1D1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GLT1D1 Gene

Proteins for GLT1D1 Gene

  • Protein details for GLT1D1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Glycosyltransferase 1 domain-containing protein 1
    Protein Accession:
    Secondary Accessions:
    • Q86XG8

    Protein attributes for GLT1D1 Gene

    346 amino acids
    Molecular mass:
    38507 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for GLT1D1 Gene


neXtProt entry for GLT1D1 Gene

Post-translational modifications for GLT1D1 Gene

No Post-translational modifications

Other Protein References for GLT1D1 Gene

No data available for DME Specific Peptides for GLT1D1 Gene

Domains & Families for GLT1D1 Gene

Gene Families for GLT1D1 Gene

Protein Domains for GLT1D1 Gene


Suggested Antigen Peptide Sequences for GLT1D1 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
  • Belongs to the glycosyltransferase group 1 family. Glycosyltransferase 4 subfamily.
genes like me logo Genes that share domains with GLT1D1: view

Function for GLT1D1 Gene

Enzyme Numbers (IUBMB) for GLT1D1 Gene

Gene Ontology (GO) - Molecular Function for GLT1D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016757 transferase activity, transferring glycosyl groups IEA --
genes like me logo Genes that share ontologies with GLT1D1: view
genes like me logo Genes that share phenotypes with GLT1D1: view

Animal Model Products

  • Taconic Biosciences Mouse Models for GLT1D1

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for GLT1D1 Gene

Localization for GLT1D1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GLT1D1 Gene


Subcellular locations from

Jensen Localization Image for GLT1D1 Gene COMPARTMENTS Subcellular localization image for GLT1D1 gene
Compartment Confidence
cytosol 3
extracellular 3
mitochondrion 3

Gene Ontology (GO) - Cellular Components for GLT1D1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
GO:0005737 cytoplasm IDA --
genes like me logo Genes that share ontologies with GLT1D1: view

Pathways & Interactions for GLT1D1 Gene

SuperPathways for GLT1D1 Gene

No Data Available

Interacting Proteins for GLT1D1 Gene

Selected Interacting proteins: Q96MS3-GL1D1_HUMAN for GLT1D1 Gene via IID

Symbol External ID(s) Details

Gene Ontology (GO) - Biological Process for GLT1D1 Gene


No data available for Pathways by source and SIGNOR curated interactions for GLT1D1 Gene

Drugs & Compounds for GLT1D1 Gene

No Compound Related Data Available

Transcripts for GLT1D1 Gene

Unigene Clusters for GLT1D1 Gene

Glycosyltransferase 1 domain containing 1:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for GLT1D1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13
SP1: - -
SP2: - - - - -

Relevant External Links for GLT1D1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for GLT1D1 Gene

mRNA expression in normal human tissues for GLT1D1 Gene

mRNA differential expression in normal tissues according to GTEx for GLT1D1 Gene

This gene is overexpressed in Whole Blood (x26.7).

NURSA nuclear receptor signaling pathways regulating expression of GLT1D1 Gene:


SOURCE GeneReport for Unigene cluster for GLT1D1 Gene:

genes like me logo Genes that share expression patterns with GLT1D1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for GLT1D1 Gene

Orthologs for GLT1D1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for GLT1D1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia GLT1D1 34
  • 83.96 (n)
  • 85.34 (a)
GLT1D1 35
  • 66 (a)
(Mus musculus)
Mammalia Glt1d1 34
  • 80.58 (n)
  • 85.34 (a)
Glt1d1 16
Glt1d1 35
  • 66 (a)
(Pan troglodytes)
Mammalia GLT1D1 34
  • 99.12 (n)
  • 99.25 (a)
GLT1D1 35
  • 99 (a)
(Rattus norvegicus)
Mammalia Glt1d1 34
  • 80.7 (n)
  • 84.21 (a)
(Canis familiaris)
Mammalia GLT1D1 35
  • 66 (a)
GLT1D1 34
  • 82.33 (n)
  • 86.09 (a)
(Monodelphis domestica)
Mammalia GLT1D1 35
  • 58 (a)
(Ornithorhynchus anatinus)
Mammalia GLT1D1 35
  • 52 (a)
(Gallus gallus)
Aves GLT1D1 35
  • 48 (a)
GLT1D1 34
  • 66.81 (n)
  • 65.69 (a)
(Anolis carolinensis)
Reptilia GLT1D1 35
  • 49 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia glt1d1 34
  • 64.36 (n)
  • 63.85 (a)
(Danio rerio)
Actinopterygii Dr.14935 34
LOC101884717 34
  • 60.32 (n)
  • 60.95 (a)
GLT1D1 35
  • 42 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 24 (a)
Species where no ortholog for GLT1D1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GLT1D1 Gene

Gene Tree for GLT1D1 (if available)
Gene Tree for GLT1D1 (if available)

Paralogs for GLT1D1 Gene

No data available for Paralogs for GLT1D1 Gene

Variants for GLT1D1 Gene

Sequence variations from dbSNP and Humsavar for GLT1D1 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs7301347 -- 128,895,498(+) gtcac(C/T)caggc intron-variant
rs1616468 -- 128,958,392(-) TGTGC(A/G)CCTCT intron-variant
rs1617183 -- 128,952,741(-) TCCCA(A/G)AACTT intron-variant
rs1618057 -- 128,882,645(-) TTTGA(C/G/T)GTTCA intron-variant
rs1682456 -- 128,855,584(+) GTTAA(C/T)GGAAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for GLT1D1 Gene

Variant ID Type Subtype PubMed ID
esv2204782 CNV deletion 18987734
esv23767 CNV loss 19812545
esv2667523 CNV deletion 23128226
esv2678080 CNV deletion 23128226
esv2746675 CNV deletion 23290073
esv2746676 CNV deletion 23290073
esv2759920 CNV loss 17122850
esv3549997 CNV deletion 23714750
esv3580535 CNV loss 25503493
esv3580536 CNV loss 25503493
esv3581993 CNV gain 25503493
esv3631151 CNV gain 21293372
esv3631153 CNV gain 21293372
esv3631154 CNV loss 21293372
esv3631155 CNV loss 21293372
esv3631156 CNV gain 21293372
esv3631157 CNV loss 21293372
nsv1040831 CNV gain 25217958
nsv1051433 CNV gain 25217958
nsv1069713 CNV deletion 25765185
nsv1070145 CNV deletion 25765185
nsv1118253 CNV deletion 24896259
nsv1134276 CNV deletion 24896259
nsv516077 CNV loss 19592680
nsv521048 CNV loss 19592680
nsv526688 CNV gain 19592680
nsv560689 CNV gain 21841781
nsv560690 CNV loss 21841781
nsv818936 CNV loss 17921354
nsv826543 CNV loss 20364138
nsv832549 CNV loss 17160897
nsv929 CNV insertion 18451855
nsv952505 CNV deletion 24416366
nsv973134 CNV duplication 23825009

Variation tolerance for GLT1D1 Gene

Residual Variation Intolerance Score: 60.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.86; 48.25% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for GLT1D1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for GLT1D1 Gene

Disorders for GLT1D1 Gene

Relevant External Links for GLT1D1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for GLT1D1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GLT1D1 Gene

Publications for GLT1D1 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 46 65
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  3. Heritability and genome-wide association analysis of renal sinus fat accumulation in the Framingham Heart Study. (PMID: 22044751) Foster M.C. … Fox C.S. (BMC Med. Genet. 2011) 3 65
  4. Toward a confocal subcellular atlas of the human proteome. (PMID: 18029348) Barbe L. … Andersson-Svahn H. (Mol. Cell Proteomics 2008) 3 65
  5. The finished DNA sequence of human chromosome 12. (PMID: 16541075) Scherer S.E. … Gibbs R.A. (Nature 2006) 4 65

Products for GLT1D1 Gene

Sources for GLT1D1 Gene

Loading form....