GLRX3 Gene
protein-coding GIFtS: 53
GCID: GC10P131934
|
|
glutaredoxin 3(Previous name: thioredoxin-like 2 ) (Previous symbol: TXNL2)
| |
Aliases for GLRX3 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Glutaredoxin 31 2 | | PKC-Theta-Interacting Protein2 3 | | PICOT1 2 3 5 | | PKCq-Interacting Protein2 3 | | TXNL21 2 3 | | BA500G10.41 | | GLRX41 2 | | Thioredoxin-Like 21 | | GRX31 2 | | TXNL32 | | GRX41 2 | | Glutaredoxin 42 | | Thioredoxin-Like Protein 22 3 | | Glutaredoxin-31 | | PKC-Interacting Cousin Of Thioredoxin2 3 | | |
Export aliases for GLRX3 gene to outside databasesPrevious GC identifers: GC10P131826 GC10P125514 |
Summaries for GLRX3 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for GLRX3: This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a varietyof substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of proteinkinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expressionof this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9.Alternatively spliced transcript variants have been observed for this gene. (provided by RefSeq, Dec 2010) UniProtKB/Swiss-Prot: GLRX3_HUMAN, O76003Function: Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). Mayplay a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since itlacks the conserved motif that is essential for catalytic activity Gene Wiki entry for GLRX3
|
Genomic Views for GLRX3 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000010.10 NC_018921.1 NT_008818.16
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the GLRX3 gene promoter: SRF AhR NRSF form 1 SRF (504 AA) POU6F1 (c2) Nkx2-5 NRSF form 2 Arnt ZIC2/Zic2 Other transcription factors
Search SABiosciences Chromatin IP Primers for GLRX3
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GLRX3 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 10q26 Ensembl cytogenetic band: 10q26.3 HGNC cytogenetic band: 10q26GLRX3 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 10 GeneLoc Exon Structure GeneLoc location for GC10P131934: view genomic region
(about GC identifiers)
Start:
|
131,934,663 bp from pter |
End:
|
131,982,785 bp from pter |
Size:
|
48,123 bases |
Orientation:
|
plus strand |
|
Proteins for GLRX3 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: GLRX3_HUMAN, O76003 (See
protein sequence)Recommended Name: Glutaredoxin-3 Size: 335 amino acids; 37432 Da
Subunit: Monomer and homodimer; the homodimer is probably linked by 2 2Fe-2S clusters that may serve as a redox sensor.The monomer interacts with other proteins. Interacts (via N-terminus) with PRKCQ/PKC-theta. Interacts (via C-terminus)with CSRP3 (By similarity). Interacts with CSRP2 (By similarity)
Subcellular location: Cytoplasm, cell cortex. Cytoplasm, myofibril, sarcomere, Z line (By similarity). Note=Under theplasma membrane. After PMA stimulation, GLRX3 and PRKCQ/PKC-theta translocate to a more extended submembrane area. Inthe Z line, found associated with CSRP3 (By similarity)
4 PDB 3D structures from and Proteopedia for GLRX3:2DIY (3D)
  2WZ9 (3D)
  2YAN (3D)
  3ZYW (3D)
 
Secondary accessions: B3KMP7 B3KMQ5 D3DRG2 Q5JV01 Q96CE0 Q9P1B0 Q9P1B1Explore the universe of human proteins at neXtProt for GLRX3: NX_O76003
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O76003 GLRX3 Protein expression data from MOPED and PaxDb: About this image 
 REFSEQ proteins (2 alternative transcripts):
NP_001186797.1 NP_006532.2 ENSEMBL proteins: ENSP00000330836 ENSP00000357633 ENSP00000435445 Human Recombinant Protein Products for GLRX3:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
GLRX3 for ontologies About GeneDecksing
GLRX3 Antibody Products: Assay Products for GLRX3: |
Protein
Domains / Families for GLRX3 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
GLRX3 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O76003ProtoNet protein and cluster: O76003 2 Blocks protein families: IPB002109 Glutaredoxin IPB006662 Thioredoxin type domain
UniProtKB/Swiss-Prot: GLRX3_HUMAN, O76003Domain: The thioredoxin domain lacks the two redox-active cysteines. This strongly suggests that it lacks thioredoxinactivitySimilarity: Contains 2 glutaredoxin domainsSimilarity: Contains 1 thioredoxin domain |
Function for GLRX3 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: UniProtKB/Swiss-Prot Summary: GLRX3_HUMAN, O76003Function: Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). Mayplay a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since itlacks the conserved motif that is essential for catalytic activity Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table
GLRX3 for ontologies About GeneDecksing
Phenotypes: 1 GenomeRNAi human phenotype for GLRX3: 8 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Glrx3):
GLRX3 for phenotypes About GeneDecksing
Animal Models:
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GLRX3 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GLRX3 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): GLRX3 (NM_006541) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for GLRX3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GLRX3  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GLRX3 |
|
Pathways & Interactions for GLRX3 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GLRX3
STRING Interaction
Network Preview (showing 5 interactants - click image to see 24)
 5/76 Interacting proteins for GLRX3 (O760031, 2, 3 ENSP000003308364) via UniProtKB, MINT, STRING, and/or I2D (see all 76)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| CIAPIN1 | Q6FI812, 3, ENSP000003779144 | MINT-67821 I2D:
score=6 STRING: ENSP00000377914 | | EFEMP2 | O959672, 3, ENSP000003099534 | MINT-67284 I2D:
score=4 STRING: ENSP00000309953 | | FRA10AC1 | Q70Z532, 3, ENSP000003604884 | MINT-64736 I2D:
score=4 STRING: ENSP00000360488 | | PRKCQ | Q047591, 3, ENSP000002631254 | EBI-374781,EBI-374762 I2D:
score=4 STRING: ENSP00000263125 | | HEXDC | Q8WVB32, 3 | MINT-65043 I2D:
score=5 | About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0002026 | regulation of the force of heart contraction |
ISS | 18258855 | | GO:0010614 | negative regulation of cardiac muscle hypertrophy |
ISS | -- | | GO:0045454 | cell redox homeostasis |
IEA | -- |
GLRX3 for ontologies About GeneDecksing
|
Drugs & Compounds for GLRX3 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
GLRX3 for compounds About GeneDecksing
Browse Tocris compounds for GLRX3 3 Novoseek chemical compound relationships for GLRX3 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| dithiol |
55.5 |
1 |
1778302 (1) |
| cyanogen bromide |
43.2 |
1 |
8119877 (1) |
| calcium |
0 |
1 |
15050380 (1) |
Search CenterWatch for drugs/clinical trials and news about GLRX3 
|
Transcripts for GLRX3 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for GLRX3 gene (2 alternative transcripts): NM_001199868.1 NM_006541.4 Unigene Cluster for GLRX3: Glutaredoxin 3 Hs.42644 [show with all ESTs]Unigene Representative Sequence: NM_0011998685 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000331244(uc001lkm.2 uc021qay.1) ENST00000368644(uc001lkn.2) ENST00000481034(uc001lko.3) ENST00000486974 ENST00000496195
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GLRX3 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GLRX3 (see all 2) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): GLRX3 (NM_006541) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for GLRX3 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GLRX3  |
Additional cDNA sequence: AF118649.1 AF118652.1 AK022131.1 AK225609.1 BC005289.1 BC014372.1 15 DOTS entries: DT.118290 DT.100788931 DT.100788929 DT.100764688 DT.65285361 DT.121267145 DT.100700023 DT.121332565 DT.95306744 DT.121267152 DT.40112243 DT.95238354 DT.100044571 DT.70101531 DT.95238366 24/371 AceView cDNA sequences (see all 371): W73191 BE220574 AF118652 BQ717738 AI628153 BU631069 AI339481 F09043 AI755205 CN483124 AI982692 CA432473 AW273006 BF435468 CR625572 CR602310 BX282433 AW769179 BU187566 BG251536 CA423693 BE896085 AA777016 CR625408 GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for GLRX3 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | |
| SP1: | |   | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | - |   | |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for GLRX3
|
Expression for GLRX3 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| GLRX3 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: --
 About this image See GLRX3 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for GLRX3
SOURCE GeneReport for Unigene cluster: Hs.42644
UniProtKB/Swiss-Prot: GLRX3_HUMAN, O76003Tissue specificity: Expressed in heart, spleen, testis and, to a lower extent, in thymus and peripheral bloodleukocytes. Weakly expressed in lung, placenta, colon and small intestine SABiosciences Custom PCR Arrays for GLRX3
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GLRX3 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat GLRX3 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GLRX3 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GLRX3 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GLRX3 |
Orthologs for GLRX3 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for GLRX3 gene from 11/40 species (see all 40) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
Glrx31 , 5 |
glutaredoxin 31, 5 |
90.15(n)1 92.84(a)1 |
  |
7 (82.32 cM)5 309261 NM_023140.41 NP_075629.21 1374376485 |
chicken (Gallus gallus) |
Aves |
GLRX31 |
glutaredoxin 3 |
78.49(n) 81.96(a) |
  |
423968 XM_421826.3 XP_421826.1 |
lizard (Anolis carolinensis) |
Reptilia |
GLRX36 |
-- |
79(a) |
1 ↔ 1 |
3(56059334-56087817) |
African clawed frog (Xenopus laevis) |
Amphibia |
Xl.92032 |
Xenopus laevis transcribed sequence with moderate similarity more |
73.37(n) |
  |
BU901136.1 |
zebrafish (Danio rerio) |
Actinopterygii |
wufb38e092 |
Transcribed sequence with weak similarity to protein more |
75.32(n) |
  |
CK240060.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
CG65236 |
-- |
45(a) |
1 ↔ 1 |
2L(13366466-13367410) |
worm (Caenorhabditis elegans) |
Secernentea |
glrx-31 |
Protein GLRX-3 |
57.27(n) 52.92(a) |
  |
178828 NM_001028585.2 NP_001023756.1 |
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes |
GRX4(YER174C)4 GRX31 |
Hydroperoxide and superoxide-radical responsive glutathione-dependent more4 Grx3p1 |
49.51(n)1 45.63(a)1 |
  |
5(539168-538434)4 8516721 NP_010383.31 8569214 NP_011101.14 |
thale cress (Arabidopsis thaliana) |
eudicotyledons |
AT4G049501 |
monothiol glutaredoxin-S17 |
58.15(n) 50.79(a) |
  |
825835 NM_116733.3 NP_192404.1 |
rice (Oryza sativa) |
Liliopsida |
Os.115762 |
Oryza sativa (japonica cultivar-group) cDNA clone0 more |
77.04(n) |
  |
AK059628.1 |
ENSEMBL Gene Tree for GLRX3 (if available) TreeFam Gene Tree for GLRX3 (if available)  |
Paralogs for GLRX3 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for GLRX3 gene
GLRX3 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for GLRX3 PGOHUM00000243473 PGOHUM00000235984
|
Genomic Variants for GLRX3 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 10 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for GLRX3 (131934663 - 131982785 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for GLRX3: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GLRX3 |
|
Disorders
/ Diseases for GLRX3 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
GLRX3 for disorders About GeneDecksing
OMIM gene information: 612754
OMIM disorders: --
8 diseases for GLRX3: About MalaCardslymphocytic choriomeningitis muscle hypertrophy hodgkin's lymphoma alzheimer's disease lung carcinoma colorectal cancer carcinoma malaria 1 disease from the University of Copenhagen DISEASES database for GLRX3:Lymphocytic choriomeningitis Human Genome Epidemiology (HuGE) Navigator: GLRX3 (2 documents) Export disorders for GLRX3 gene to outside databases
|
Publications for GLRX3 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for GLRX3 gene, integrated from 9 sources (see all 95): (articles sorted by number of sources associating them with GLRX3) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Characterization of 16 novel human genes showing high similarity to yeast sequences. (PubMed id 11124703)1, 2, 3 Stanchi F.... Valle G. (2001)
- Inhibition of the c-Jun N-terminal kinase/AP-1 and NF-kappaB pathways by PICOT, a novel protein kinase C-interacting protein with a thioredoxin homology domain. (PubMed id 10636891)1, 2, 3 Witte S.... Altman A. (2000)
- Characterization of the human monothiol glutaredoxin 3 (PICOT) as iron-sulfur protein. (PubMed id 20226171)1, 2 Haunhorst P....Lillig C.H. (2010)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Preferential overexpression of glutaredoxin3 in human colon and lung carcinoma. (PubMed id 19797004)1, 9 Cha M.K. and Kim I.H. (2009)
- A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
- Human glutaredoxin 3 forms [2Fe-2S]-bridged complexes with human BolA2. (PubMed id 22309771)1 Li H....Outten C.E. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
|
External Searches for GLRX3 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing GLRX3 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing GLRX3 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing GLRX3 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for GLRX3 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for GLRX3 gene: Search GeneIP for patents involving GLRX3
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products for GLRX3 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for GLRX3 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GLRX3 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GLRX3 | | OriGene Protein Over-expression Lysate for GLRX3 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for GLRX3 | | OriGene 3'-UTR Clone for GLRX3 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GLRX3 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GLRX3 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for GLRX3 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for GLRX3 | | OriGene Custom Protein Services for GLRX3 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat GLRX3 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GLRX3 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GLRX3 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GLRX3 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GLRX3 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GLRX3 |
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| | | Search Tocris compounds for GLRX3 |
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 | | GLRX3 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GLRX3 |
|  |  |  |  | | | ThermoFisher Antibodies for GLRX3 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GLRX3 |
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