GLRX2 Gene
protein-coding GIFtS: 54
GCID: GC01M193065
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|
glutaredoxin 2
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Aliases for GLRX2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Glutaredoxin 21 2 | | GRX21 2 3 5 | | BA101E13.11 | | CGI-1332 | | BA101E13.1 (GRX2 Glutaredoxin (Thioltransferase) 2)2 |
Export aliases for GLRX2 gene to outside databasesPrevious GC identifers: GC01M190855 GC01M188579 GC01M189532 GC01M190353 GC01M189797 GC01M191332 GC01M164301 |
Summaries for GLRX2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for GLRX2: The protein encoded by this gene is a member of the glutaredoxin family of proteins, which maintain cellular thiolhomeostasis. These proteins are thiol-disulfide oxidoreductases that use a glutathione-binding site and one or twoactive cysteines in their active site. This gene undergoes alternative splicing to produce multiple isoforms, one ofwhich is ubiquitously expressed and localizes to mitochondria, where it functions in mitochondrial redox homeostasisand is important for the protection against and recovery from oxidative stress. Other isoforms, which have morerestrictive expression patterns, show cytosolic and nuclear localization, and are thought to function in cellulardifferentiation and transformation, possibly with a role in tumor progression. (provided by RefSeq, Aug 2011) UniProtKB/Swiss-Prot: GLRX2_HUMAN, Q9NS18Function: Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis uponinduction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosiscaused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity forprotein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxinreductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation anddeglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex.Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release Gene Wiki entry for GLRX2
|
Genomic Views for GLRX2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the GLRX2 gene promoter: MEF-2A aMEF-2 ITF-2 E47 GATA-1 Other transcription factors
Search SABiosciences Chromatin IP Primers for GLRX2
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GLRX2 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q31.2 Ensembl cytogenetic band: 1q31.2 HGNC cytogenetic band: 1q31.2GLRX2 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M193065: view genomic region
(about GC identifiers)
Start:
|
193,065,598 bp from pter |
End:
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193,075,244 bp from pter |
Size:
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9,647 bases |
Orientation:
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minus strand |
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Proteins for GLRX2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: GLRX2_HUMAN, Q9NS18 (See
protein sequence)Recommended Name: Glutaredoxin-2, mitochondrial precursor Size: 164 amino acids; 18052 Da
Subunit: Monomer; active form. Homodimer; inactive form. The homodimer is probably linked by 1 2Fe-2S cluster
Subcellular location: Isoform 1: Mitochondrion
Subcellular location: Isoform 2: Nucleus
Miscellaneous: The absence of GLRX2 dramatically sensitizes cells to cell death induced by doxorubicin/adriamycin andphenylarsine oxide
Sequence caution: Sequence=AAD34128.1; Type=Frameshift; Positions=Several; Sequence=AAH28113.1; Type=Erroneousinitiation;
3 PDB 3D structures from and Proteopedia for GLRX2:2CQ9 (3D)
  2FLS (3D)
  2HT9 (3D)
 
Secondary accessions: Q3LR69 Q7L1N7 Q96JC0 Q9Y3D4Alternative splicing: 2 isoforms: Q9NS18-1 Q9NS18-2 (Variant in position: 40:R->W)Explore the universe of human proteins at neXtProt for GLRX2: NX_Q9NS18
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NS18 GLRX2 Protein expression data from MOPED and PaxDb: About this image 
 REFSEQ proteins (3 alternative transcripts):
NP_001230328.1 NP_057150.2 NP_932066.1 ENSEMBL proteins: ENSP00000356409 ENSP00000356410 Human Recombinant Protein Products for GLRX2:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
GLRX2 for ontologies About GeneDecksing
GLRX2 Antibody Products: Assay Products for GLRX2: |
Protein
Domains / Families for GLRX2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
GLRX2 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9NS18ProtoNet protein and cluster: Q9NS18 1 Blocks protein family: IPB002109 Glutaredoxin
UniProtKB/Swiss-Prot: GLRX2_HUMAN, Q9NS18Similarity: Belongs to the glutaredoxin familySimilarity: Contains 1 glutaredoxin domain |
Function for GLRX2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: UniProtKB/Swiss-Prot Summary: GLRX2_HUMAN, Q9NS18Function: Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis uponinduction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosiscaused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity forprotein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxinreductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation anddeglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex.Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c releaseEnzyme regulation: The 2Fe-2S present in the homodimer leads to inactivation of the enzyme. The 2Fe-2S may serve as aredox sensor: the presence of one-electron oxidants or reductants leading to the loss of the 2Fe-2S cluster,subsequent monomerization and activation of the enzyme. Unlike other glutaredoxins, it is not inhibited by oxidationof structural Cys residuesBiophysicochemical properties: Kinetic parameters: KM=5.9 mM for GSH; KM=0.77 mM for glutathionylated ribonuclease A;KM=4.3 mM for glutathionylated BSA; KM=0.11 mM for glutathionylated beta-mercaptoethanol; Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7): About this table
GLRX2 for ontologies About GeneDecksing
Phenotypes: 2 GenomeRNAi human phenotypes for GLRX2: 2 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Glrx2):
GLRX2 for phenotypes About GeneDecksing
Animal Models: Mouse knock-out Glrx2tm1Ysh for GLRX2
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GLRX2 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GLRX2 (see all 3) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GLRX2 |
|
Pathways & Interactions for GLRX2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | PAK Pathway | |
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for GLRX2
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GLRX2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 7)
 5/7 Interacting proteins for GLRX2 (Q9NS183 ENSP000003564104) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
Gene Ontology (GO): 5/13 biological process terms (GO ID links to tree view) (see all 13): About this table
GLRX2 for ontologies About GeneDecksing
|
Drugs & Compounds for GLRX2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
GLRX2 for compounds About GeneDecksing
Browse Tocris compounds for GLRX2
1 DrugBank Compound for GLRX2 About this table
6 Novoseek chemical compound relationships for GLRX2 gene About this table
Search CenterWatch for drugs/clinical trials and news about GLRX2 
|
Transcripts for GLRX2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for GLRX2 gene (3 alternative transcripts): NM_001243399.1 NM_016066.4 NM_197962.2 Unigene Cluster for GLRX2: Glutaredoxin 2 Hs.458283 [show with all ESTs]Unigene Representative Sequence: BM9081283 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000367439(uc001gsz.2) ENST00000367440(uc021pgp.1 uc001gta.2) ENST00000472197
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GLRX2 (see all 5) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GLRX2 (see all 3) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): GLRX2 (NM_016066) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for GLRX2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GLRX2  |
Additional cDNA sequence: AF132495.2 AF151891.1 AF290514.1 AY038988.1 BC009669.1 BC028113.1 3 DOTS entries: DT.409088 DT.100658989 DT.92422256 24/50 AceView cDNA sequences (see all 50): AI929473 AY038988 NM_197962 BF968364 BC009669 AI929534 AI929492 AA887118 NM_016066 CD679257 AI929431 AW157841 AW161388 AF290514 BE788889 AL038711 BU155397 BM887926 AF132495 AA421273 BI858718 BC028113 AI929588 BQ432881 GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for GLRX2 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | |
| SP1: | |   | |   | |   | - |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | - |   | - |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for GLRX2
|
Expression for GLRX2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| GLRX2 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CATTGTCTTC
 About this image See GLRX2 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for GLRX2
SOURCE GeneReport for Unigene cluster: Hs.458283
UniProtKB/Swiss-Prot: GLRX2_HUMAN, Q9NS18Tissue specificity: Widely expressed. Expressed in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver,small intestine, placenta and lung. Not expressed in peripheral blood leukocytes SABiosciences Expression via Pathway-Focused PCR Array including GLRX2: | Nitric Oxide Signaling Pathway in human mouse rat |
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GLRX2 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat GLRX2 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GLRX2 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GLRX2 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GLRX2 |
Orthologs for GLRX2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for GLRX2 gene from 7/27 species (see all 27) About this table
ENSEMBL Gene Tree for GLRX2 (if available) TreeFam Gene Tree for GLRX2 (if available)  |
Paralogs for GLRX2 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for GLRX2 gene
- GLRX2
3 SIMAP similar genes for GLRX2 using alignment to 2 protein entries: GLRX2_HUMAN (see all proteins):GLRX TXNRD1 TXNRD3
GLRX2 for paralogs About GeneDecksing
|
Genomic Variants for GLRX2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 1 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for GLRX2 (193065598 - 193075244 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for GLRX2: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GLRX2 |
|
Disorders
/ Diseases for GLRX2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
GLRX2 for disorders About GeneDecksing
OMIM gene information: 606820
OMIM disorders: --
8 diseases for GLRX2: About MalaCardsinterstitial lung disease parkinson's disease lung cancer ischemia cervicitis melanoma malaria neuronitis Human Genome Epidemiology (HuGE) Navigator: GLRX2 (1 document) Export disorders for GLRX2 gene to outside databases
|
Publications for GLRX2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for GLRX2 gene, integrated from 9 sources (see all 58): (articles sorted by number of sources associating them with GLRX2) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Cloning and expression of a novel human glutaredoxin (Grx2) with mitochondrial and nuclear isoforms. (PubMed id 11297543)1, 2, 3, 9 Lundberg M.... Holmgren A. (2001)
- Identification and characterization of a new mammalian glutaredoxin (thioltransferase), Grx2. (PubMed id 11397793)1, 2, 9 Gladyshev V.N.... Lou M.F. (2001)
- Characterization of human glutaredoxin 2 as iron-sulfur protein: a possible role as redox sensor. (PubMed id 15917333)1, 2, 9 Lillig C.H.... Holmgren A. (2005)
- Human mitochondrial glutaredoxin reduces S-glutathionylated proteins with high affinity accepting electrons from either glutathione or thioredoxin reductase. (PubMed id 14676218)1, 2, 9 Johansson C.... Holmgren A. (2004)
- Overexpression of glutaredoxin 2 attenuates apoptosis by preventing cytochrome c release. (PubMed id 15649413)1, 2, 9 Enoksson M....Orrenius S. (2005)
- Short interfering RNA-mediated silencing of glutaredoxin 2 increases the sensitivity of HeLa cells toward doxorubicin and phenylarsine oxide. (PubMed id 15328416)1, 2, 9 Lillig C.H.... Holmgren A. (2004)
- Reversible sequestration of active site cysteines in a 2Fe-2S-bridged dimer provides a mechanism for glutaredoxin 2 regulation in human mitochondria. (PubMed id 17121859)1, 2, 9 Johansson C....Oppermann U. (2007)
- Oxidation and S-nitrosylation of cysteines in human cytosolic and mitochondrial glutaredoxins: effects on structure and activity. (PubMed id 17355958)1, 7 Hashemy S.I....Holmgren A. (2007)
- Redox properties and evolution of human glutaredoxins. (PubMed id 17546662)1, 7 Sagemark J....Berndt K.D. (2007)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
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External Searches for GLRX2 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing GLRX2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing GLRX2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing GLRX2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for GLRX2 | Pharmacogenomics, SNPs, Pathways | | NIEHS-SNPs | http://egp.gs.washington.edu/data/glrx2/ |
|
| | |
About This Section
| Patent Information for GLRX2 gene: Search GeneIP for patents involving GLRX2
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for GLRX2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
|
 | |
 | |
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