GLRA1 Gene protein-coding GIFtS : 67 GCID: GC05 M151182
Glycine Receptor, Alpha 1 glycine receptor, alpha 1 (startle disease/hyperekplexia) )STHE )
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Aliasesfor GLRA1 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
10 fRNAdb ,
12 H-InvDB ,
13 NCBI ,
14 NONCODE ,
and/or 15 RNAdb )About This Section Aliases Glycine Receptor, Alpha 1 1 2 Startle Disease/Hyperekplexia1 STHE1 2 5 Stiff Person Syndrome1 Glycine Receptor 48 KDa Subunit2 3 HKPX12 Glycine Receptor Strychnine-Binding Subunit2 3 Glycine Receptor Subunit Alpha-12 Glycine Receptor, Alpha 1 (Startle Disease/Hyperekplexia)1
Export aliases for GLRA1 gene to outside databases Previous GC identifers: GC05M151270 GC05M151799 GC05M151230 GC05M146347
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Summariesfor GLRA1 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for GLRA1 Gene: The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor. The receptor mediatespostsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease(STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Two transcript variantsencoding different isoforms have been found for this gene.(provided by RefSeq, Mar 2009) GeneCards Summary for GLRA1 Gene: GLRA1 (glycine receptor, alpha 1) is a protein-coding gene. Diseases associated with GLRA1 include hyperekplexia glra1-related hyperekplexia related super-pathways are SLC-mediated transmembrane transport and Stimuli-sensing channels . GO annotations related to this gene include transmitter-gated ion channel activity and glycine binding . An important paralog of this gene is GLRA2 . UniProtKB/Swiss-Prot: GLRA1_HUMAN, P23415 Function : The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptorincreases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing) summary
for GLRA1 Gene: Glycine receptors (GlyR) are members of the cys-loop family of ligand-gated ion channels, responsible formediating the inhibitory effects of glycine. They are widely distributed throughout the CNS, particularlywithin the hippocampus, spinal cord and brain stem. Glycine receptors exist as pentameric proteins,homo-oligomers of the alpha isoforms (alpha1, alpha2, alpha3 or alpha4) or hetero-oligomers which alsocontain the beta-subtype variant (beta1) which is essential for targeting the receptor to the synapse.Glycine receptors contain an integral chloride channel, and have modulatory sites for anesthetics,neurosteroids, cannabinoids and ethanol. Disruption in glycine receptor expression or ion channel functioncan result in hyperekplexia, a rare neurological disorder. Gene Wiki entry for GLRA1 (Glycine receptor, alpha 1) Gene
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Genomic Viewsfor GLRA1 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 73) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000005.9 NT_029289.11 NC_018916.2 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the GLRA1 gene promoter:NF-1 AP-4 Tal-1beta E47 RORalpha1 COMP1 Sox9 FOXO1a ITF-2 Other transcription factors Search SABiosciences Chromatin IP Primers for GLRA1 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 5q32 Ensembl cytogenetic band: 5q33.1 HGNC cytogenetic band: 5q33.1 GLRA1 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 5 GeneLoc Exon Structure
GeneLoc location for GC05M151182: view genomic region
(about GC identifiers )
Start: 151,202,074 bp from pter End:
151,304,403 bp from pter
Size: 102,330 bases Orientation:
minus strand
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Proteinsfor GLRA1 gene
(According to
UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE 1 MOPED ,
2 PaxDb , and 3 MAXQB
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Cloud-Clone Corp. ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Cloud-Clone Corp. ,
Ontologies according to Gene
Ontology Consortium 01 Oct 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
LSBio ,
Abcam , and/or
Cloud-Clone Corp. )
About This Section UniProtKB/Swiss-Prot: GLRA1_HUMAN, P23415 See
protein sequence )Recommended Name: Size : 457 amino acids; 52624 DaSubunit : Pentamer composed of three alpha and two beta subunits. Homopentamers of alpha subunits also formfunctional receptors
Subcellular location : Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cellmembrane; Multi-pass membrane protein
Miscellaneous : The alpha subunit binds strychnine2 PDB 3D structures from :1MOT (3D) 1VRY (3D) Secondary accessions : B2R6T3 Q14C77 Q6DJV9Alternative splicing : 2 isoforms : P23415-1 P23415-2 Explore the universe of human proteins at neXtProt for GLRA1: NX_P23415 Explore proteomics data for GLRA1 at MOPED Post-translational modifications:
View modification sites using PhosphoSitePlus View neXtProt modification sites for NX_P23415 GLRA1 Protein expression data from MOPED1 2 3 : About this image REFSEQ proteins (2 alternative transcripts): NP_000162.2 NP_001139512.1 ENSEMBL proteins: ENSP00000274576 ENSP00000430595 ENSP00000411593 ENSP00000445913 Reactome Protein details: P23415 Human Recombinant Protein Products for GLRA1: Gene Ontology (GO): 5/11 cellular component terms (GO ID links to tree view) (see all 11 ): About this table
About GeneDecksing GLRA1 Antibody Products: Assay Products for GLRA1:
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Protein
Domains /for GLRA1 gene (According to HGNC , IUPHAR , InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section HGNC Gene Families: GLRA: Ligand-gated ion channels / Glycine receptors IUPHAR Guide to PHARMACOLOGY protein family classification: α1 Glycine receptors 5/7 InterPro protein domains (see all 7 ):
Graphical View of Domain Structure for InterPro Entry P23415 ProtoNet protein and cluster: P23415
3 Blocks protein domains : IPB006028 IPB006201 IPB008128 UniProtKB/Swiss-Prot: GLRA1_HUMAN, P23415 Similarity : Belongs to the ligand-gated ion channel (TC 1.A.9) family. Glycine receptor (TC 1.A.9.3) subfamily.GLRA1 sub-subfamily About GeneDecksing
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Functionfor GLRA1 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
genOway ,
SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
Vector BioLabs ,
and Sirion Biotech ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene .)
About This Section Molecular Function: UniProtKB/Swiss-Prot Summary: GLRA1_HUMAN, P23415 Function : The glycine receptor is a neurotransmitter-gated ion channel. Binding of glycine to its receptorincreases the chloride conductance and thus produces hyperpolarization (inhibition of neuronal firing)
Genatlas biochemistry entry for GLRA1 glycine receptor,alpha 1 subunit,inhibitory Gene Ontology (GO): 5/7 molecular function terms (GO ID links to tree view) (see all 7 ): About this table
About GeneDecksing Phenotypes: 11 MGI mutant phenotypes (inferred from 8 alleles(MGI details for Glra1) :About GeneDecksing Animal Models: Cell Line GenScript Custom overexpressing Cell Line Services for GLRA1 Search LifeMap BioReagents cell lines for GLRA1 In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GLRA1
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Pathways & Interactionsfor GLRA1 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Sino Biological ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Oct 2013 via
Entrez Gene) .
About This Section SuperPaths for GLRA1 About See pathways by source SuperPath Contained pathways About 1 SLC-mediated transmembrane transport 2 Ion channel transport 3 GABA A receptor activation 4 PKA activation in glucagon signalling 5 Class A/1 (Rhodopsin-like receptors)
Pathways by source See SuperPaths Show all pathways 1 1 3 1 (Kegg details for GLRA1) :About GeneDecksing Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GLRA1 STRING Interaction
Network Preview (showing 4 interactants - click image to see more details)4 Interacting proteins for GLRA1 (ENSP00000274576 4 via UniProtKB, MINT, STRING , and/or I2D About this table Gene Ontology (GO): 5/26 biological process terms (GO ID links to tree view) (see all 26 ): About this table
About GeneDecksing
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Drugs & Compoundsfor GLRA1 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek ,
Ligands according to IUPHAR ,
and Drugs according to DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section About GeneDecksing Compounds for GLRA1 available from Tocris Bioscience About this table Compound Action
CAS
# beta-Alanine Endogenous glycine agonist, more selective than taurine (Cat. No. 0209) [107-95-9] Hypotaurine Non-selective endogenous glycine receptor agonist [300-84-5] L-Serine Weak endogenous glycine receptor agonist [56-45-1] L-Alanine Glycine receptor agonist [56-41-7] Taurine Non-selective, endogenous glycine receptor partial agonist [107-35-7]
4 HMDB Compounds for GLRA1 About this table 10/11 DrugBank Compounds for GLRA1 (see all 11 )About this table 10/21 IUPHAR Ligands for GLRA1 (α1) (see all 21 )About this table 5 Novoseek inferred chemical compound relationships for GLRA1 gene About this table
Compound
-log (P-Val)
Hits
PubMed IDs for Articles with Shared Sentences (# sentences)
clonazepam
71.6
2
1355335 (1), 16429380 (1)
strychnine
68.2
1
9144769 (1)
picrotoxin
36.8
1
11744711 (1)
glutamate
7.99
1
20525074 (1)
arginine
7.81
1
11973623 (1)
GLRA1
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Transcriptsfor GLRA1 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , KenesGroup ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Sirion Biotech ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for GLRA1 gene (2 alternative transcripts): NM_000171.3 NM_001146040.1 Unigene Cluster for GLRA1:
Glycine receptor, alpha 1 Hs.121490 [show with all ESTs ] Unigene Representative Sequence: NM_001146040 5 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000274576 (uc003lur.3 uc003lut.3 uc003lus.3 ) ENST00000462581 ENST00000455880 ENST00000471351 ENST00000545569 Primer GLRA1 human mouse SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat
Additional mRNA sequence: AK308539.1 AK312702.1 BC074980.2 BC114947.1 X52009.1
2 DOTS entries : DT.92014914 DT.120823005
3 AceView cDNA sequences :
BC074980 NM_000171 X52009 GeneLoc Exon Structure 2 Alternative Splicing Database (ASD) splice patterns (SP) for GLRA1 About this scheme ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 SP1 : SP2 : -
ECgene alternative splicing isoforms for GLRA1
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Expression for GLRA1 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section GLRA1 expression in normal human tissues
(normalized intensities) GLRA1 embryonic expression: see See probesets specificity/sensitivity at GeneAnnot About this image BioGPS 2/3 CGAP TAG: -- About this image
GLRA1 expression in embryonic tissues and stem cells About this table LifeMap ,
the Embryonic Development and Stem Cells Database 5/3 selected tissues (see all 3 ) fully expand See GLRA1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for GLRA1 SOURCE GeneReport for Unigene cluster: Hs.121490 SABiosciences Custom PCR Arrays for GLRA1 Primer GLRA1 human mouse SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GLRA1
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Orthologsfor GLRA1 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section Orthologs for GLRA1 gene from 6/15 species (see all 15 ) About this table
Organism
Taxonomic
Gene
Description
Human
Orthology
Details
mouse Mammalia Glra11 5
glycine receptor, alpha 1 subunit1, 5
90.79(n) 1 98.89(a) 1
11 (33.12 cM) 5 14654 1 NM_020492.3 1 NP_065238.2 1 55514238 5
chicken Aves GLRA11
glycine receptor, alpha 1
84.26(n) 96.66(a)
427637 XM_425210.2 XP_425210.2
lizard Reptilia GLRA16
Uncharacterized protein
85(a)
1 ↔ 1
GL343248.1(114481-208717)
zebrafish Actinopterygii glra12
glycine receptor, alpha 1
79.54(n)
30676 AF488379.1
fruit fly Insecta Rdl3 1
response to cyclodiene GABA-A receptor3 1
44(a) 3 51.88(n) 1 43.22(a) 1
3 67A13 42350 1 NM_001014641.2 1 NP_001014641.1 1
worm Secernentea glc-31 3
ligand-gated ionic channel subunit3 1
47(a) 3 48.99(n) 1 43.72(a) 1
V(5449241-5453240)3 178930 1 NM_072040.4 1 NP_504441.1 1
ENSEMBL Gene Tree for GLRA1 (if available)TreeFam Gene Tree for GLRA1 (if available)
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Paralogsfor GLRA1 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for GLRA1 gene GLRA2 2 GABRR1 2 GLRB 2 GABRB1 2 GABRD 2 GABRP 2 GLRA4 2 GABRB3 2 GABRB2 2 GABRQ 2 GLRA3 2 GABRR2 2 18/24 SIMAP similar genes for GLRA1 using alignment to 3 protein entries: GLRA1_HUMAN (see all proteins )
(see all similar genes ):GLRA2 GLRA3 GLRA4 GABRP GABRA4 GABRQ GABRR3 GABRR2 GABRA2 GABRR1 GABRA5 GABRE GABRA1 GABRD GABRG3 GLRB GABRG2 GABRA6 About GeneDecksing
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Genomic Variantsfor GLRA1 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
4 UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical Chr 5 pos Sequence # AA Type More # Allele Pop Total More
HapMap Linkage Disequilibrium report for GLRA1 (151202074 - 151304403 bp)
Structural Variations Database of Genomic Variants (DGV) 3 variations for GLRA1 : About this table Human Gene Mutation Database (HGMD) : GLRA1 Locus Specific Mutation Databases (LSDB): GLRA1 SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human mouse rat
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Disorders
/ Diseasesfor GLRA1 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Conferences by KenesGroup ,
Novoseek , Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section OMIM gene information: 138491 OMIM disorders : 149400 UniProtKB/Swiss-Prot: GLRA1_HUMAN, P23415 Hyperekplexia 1 (HKPX1) [MIM:149400]: A neurologic disorder characterized by muscular rigidity of centralnervous system origin, particularly in the neonatal period, and by an exaggerated startle response to unexpectedacoustic or tactile stimuli. Note=The disease is caused by mutations affecting the gene represented in this entry 17 : About MalaCards hyperekplexia glra1-related hyperekplexia aspiration pneumonia startle disease/hyperekplexia, autosomal dominant stiff-person syndrome molybdenum cofactor deficiency spastic paraparesis spasticity pneumonia amyotrophic lateral sclerosis lateral sclerosis mental retardation alcoholism cerebritis alzheimer's disease lung cancer neuronitis 1 disease from the University of Copenhagen DISEASES database for GLRA1 :Aspiration pneumonia About GeneDecksing Congresses - knowledge worth sharing: Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015 2 Novoseek inferred disease relationships for GLRA1 gene About this table
GeneTests: GLRA1 GeneReviews: GLRA1 Genetic Association Database (GAD): GLRA1 Human Genome Epidemiology (HuGE) Navigator: GLRA1 (5 documents) Export disorders for GLRA1 gene to outside databases
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Publicationsfor GLRA1 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for GLRA1 gene, integrated from 9 sources (see all 162 ):(articles sorted by number of sources associating them with GLRA1) Utopia : connect your pdf to the dynamic
Mutations in the alpha 1 subunit of the inhibitory glycine receptor cause the dominant neurologic disorder, hyperekplexia. (PubMed id 8298642) 1 , 2 , 3, 9(1993) Mutational analysis of familial and sporadic hyperekplexia. (PubMed id 7611730) 1 , 2 , 9(1995) Hyperekplexia phenotype due to compound heterozygosity for GLRA1 gene mutations. (PubMed id 10514101) 1 , 2 , 9(1999) Novel GLRA1 missense mutation (P250T) in dominant hyperekplexia defines an intracellular determinant of glycine receptor channel gating. (PubMed id 9920650) 1 , 2 , 9(1999) Analysis of GLRA1 in hereditary and sporadic hyperekplexia: a novel mutation in a family cosegregating for hyperekplexia and spastic paraparesis. (PubMed id 8733061) 1 , 2 , 9(1996) Alanine-scanning mutagenesis in the signature disulfide loop of the glycine receptor alpha 1 subunit: critical residues for activation and modulation. (PubMed id 15287733) 1 , 7, 9(2004) A novel mutation (Gln266-->His) in the alpha 1 subunit of the inhibitory glycine-receptor gene (GLRA1) in hereditary hyperekplexia. (PubMed id 8571969) 1 , 2 , 9(1996) Startle disease, or hyperekplexia: response to clonazepam and assignment of the gene (STHE) to chromosome 5q by linkage analysis. (PubMed id 1355335) 1 , 3, 9(1992) Decreased agonist affinity and chloride conductance of mutant glycine receptors associated with human hereditary hyperekplexia. (PubMed id 7925268) 1 , 2 , 9(1994) Genetical genomic determinants of alcohol consumption in rats and humans. (PubMed id 19874574) 1 , 4(2009)
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External Searches for GLRA1 gene
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Genome Databases showing GLRA1 gene
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Other Databases showing GLRA1 gene
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Specialized Databases showing GLRA1 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description PharmGKB entry for GLRA1 Pharmacogenomics, SNPs, Pathways GeneReviews http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/GLRA1
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About This Section Patent Information for GLRA1 gene: GLRA1 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor GLRA1 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Cloud-Clone Corp. , Thermo Fisher Scientific , LSBio , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Sirion Biotech , Cell lines from GenScript , and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory ,
genOway )About This Section
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat GLRA1 QIAGEN SeqTarget long-range PCR primers in human mouse rat QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human mouse rat QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat
Tocris compounds for GLRA1
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GLRA1
ThermoFisher Antibodies for GLRA1
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat GLRA1
LSBio Antibodies in human mouse rat
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Last full update: 23 Oct 2013 -
Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014
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