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Aliases for GLMP Gene

Aliases for GLMP Gene

  • Glycosylated Lysosomal Membrane Protein 2 3
  • Kidney Lysosomal Membrane Protein 2 3
  • Lysosomal Protein NCU-G1 3 4
  • C1orf85 3 4
  • Chromosome 1 Open Reading Frame 85 2
  • Kidney Predominant Protein NCU-G1 3
  • NCU-G1 3

External Ids for GLMP Gene

Previous HGNC Symbols for GLMP Gene

  • C1orf85

Summaries for GLMP Gene

GeneCards Summary for GLMP Gene

GLMP (Glycosylated Lysosomal Membrane Protein) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GLMP Gene

Genomics for GLMP Gene

Genomic Location for GLMP Gene

156,290,089 bp from pter
156,295,689 bp from pter
5,601 bases
Minus strand

Genomic View for GLMP Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for GLMP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GLMP Gene

No data available for Regulatory Elements for GLMP Gene

Proteins for GLMP Gene

  • Protein details for GLMP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Glycosylated lysosomal membrane protein
    Protein Accession:
    Secondary Accessions:
    • A6NH16
    • B4DJN4
    • Q5SZX4
    • Q6UX96
    • Q8IV07
    • Q96F65

    Protein attributes for GLMP Gene

    406 amino acids
    Molecular mass:
    43864 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAH11575.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAI14165.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for GLMP Gene


neXtProt entry for GLMP Gene

Proteomics data for GLMP Gene at MOPED

Post-translational modifications for GLMP Gene

No data available for DME Specific Peptides for GLMP Gene

Domains for GLMP Gene

Protein Domains for GLMP Gene


Graphical View of Domain Structure for InterPro Entry



  • Belongs to the GLMP family.
  • Belongs to the GLMP family.
genes like me logo Genes that share domains with GLMP: view

No data available for Gene Families and Suggested Antigen Peptide Sequences for GLMP Gene

Function for GLMP Gene

Molecular function for GLMP Gene

UniProtKB/Swiss-Prot Induction:
Transcription is activated by TFEB.

Gene Ontology (GO) - Molecular Function for GLMP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003700 sequence-specific DNA binding transcription factor activity IMP 18021396
GO:0004879 ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity IMP 18021396
GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity IDA 18021396
GO:0044212 transcription regulatory region DNA binding IDA 18021396
genes like me logo Genes that share ontologies with GLMP: view

Phenotypes for GLMP Gene

GenomeRNAi human phenotypes for GLMP:
genes like me logo Genes that share phenotypes with GLMP: view

miRNA for GLMP Gene

miRTarBase miRNAs that target GLMP

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for GLMP

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for GLMP Gene

Localization for GLMP Gene

Subcellular locations from UniProtKB/Swiss-Prot for GLMP Gene

Lysosome membrane; Single-pass type I membrane protein.

Gene Ontology (GO) - Cellular Components for GLMP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA 18021396
GO:0005764 lysosome IDA 19556463
GO:0005765 lysosomal membrane IEA --
GO:0005829 cytosol IDA 18021396
GO:0016021 integral component of membrane ISS --
genes like me logo Genes that share ontologies with GLMP: view

No data available for Subcellular locations from COMPARTMENTS for GLMP Gene

Pathways for GLMP Gene

SuperPathways for GLMP Gene

No Data Available

Interacting Proteins for GLMP Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000354553 Q8WWB7-GLMP_HUMAN for GLMP Gene via STRING I2D

Gene Ontology (GO) - Biological Process for GLMP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0030522 intracellular receptor signaling pathway IMP 18021396
GO:0045944 positive regulation of transcription from RNA polymerase II promoter IMP 18021396
genes like me logo Genes that share ontologies with GLMP: view

No data available for Pathways by source for GLMP Gene

Transcripts for GLMP Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for GLMP

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for GLMP Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b · 3c · 3d ^ 4a · 4b ^ 5a · 5b · 5c · 5d ^ 6a · 6b · 6c
SP1: - -
SP2: - - -
SP3: - -
SP4: - - - - -
SP5: - - -

Relevant External Links for GLMP Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for GLMP Gene

mRNA expression in normal human tissues for GLMP Gene

Protein differential expression in normal tissues for GLMP Gene

This gene is overexpressed in Amniocyte (38.3) and Liver (20.7).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for GLMP Gene

genes like me logo Genes that share expressions with GLMP: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Expression partners for GLMP Gene

Orthologs for GLMP Gene

This gene was present in the common ancestor of animals.

Orthologs for GLMP Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C3H1orf85 35
  • 86.14 (n)
  • 82.18 (a)
C1orf85 36
  • 82 (a)
(Canis familiaris)
Mammalia C7H1orf85 35
  • 84.51 (n)
  • 80.65 (a)
C1orf85 36
  • 79 (a)
(Mus musculus)
Mammalia 0610031J06Rik 35
  • 81.57 (n)
  • 80.3 (a)
0610031J06Rik 16
0610031J06Rik 36
  • 79 (a)
(Pan troglodytes)
Mammalia C1H1orf85 35
  • 99.26 (n)
  • 99.26 (a)
C1orf85 36
  • 99 (a)
(Rattus norvegicus)
Mammalia RGD1303130 35
  • 81.48 (n)
  • 80.3 (a)
(Monodelphis domestica)
Mammalia C1orf85 36
  • 53 (a)
(Ornithorhynchus anatinus)
Mammalia C1orf85 36
  • 45 (a)
(Gallus gallus)
Aves LOC777136 35
  • 56.58 (n)
  • 43.7 (a)
C1orf85 36
  • 43 (a)
(Anolis carolinensis)
Reptilia C1orf85 36
  • 41 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia c1orf85 35
  • 53.8 (n)
  • 45.56 (a)
(Danio rerio)
Actinopterygii zgc:92308 35
  • 47.67 (n)
  • 37.5 (a)
C19H1orf85 36
  • 33 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP004431 35
  • 42.11 (n)
  • 24.67 (a)
Species with no ortholog for GLMP:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GLMP Gene

Gene Tree for GLMP (if available)
Gene Tree for GLMP (if available)

Paralogs for GLMP Gene

No data available for Paralogs for GLMP Gene

Variants for GLMP Gene

Sequence variations from dbSNP and Humsavar for GLMP Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs1570805 -- 156,294,857(+) GTTGA(C/T)GCTCA missense, reference, intron-variant, nc-transcript-variant
rs1570806 -- 156,294,871(+) TGCTG(G/T)GGGGG reference, missense, intron-variant, nc-transcript-variant
rs3118199 -- 156,296,608(+) ATATA(G/T)AGAGA upstream-variant-2KB
rs3123025 -- 156,297,213(+) aaaaa(A/T)ttttt upstream-variant-2KB
rs10908494 -- 156,293,306(+) CCCAA(A/G)CCCTG intron-variant

Relevant External Links for GLMP Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for GLMP Gene

Disorders for GLMP Gene

No disorders were found for GLMP Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for GLMP Gene

Publications for GLMP Gene

  1. NCU-G1 is a highly glycosylated integral membrane protein of the lysosome. (PMID: 19489740) Schieweck O. … LA1bke T. (Biochem. J. 2009) 2 3 23
  2. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 4
  3. Human NCU-G1 can function as a transcription factor and as a nuclear receptor co-activator. (PMID: 18021396) Steffensen K.R. … Eskild W. (BMC Mol. Biol. 2007) 2 3 4
  4. A gene network regulating lysosomal biogenesis and function. (PMID: 19556463) Sardiello M. … Ballabio A. (Science 2009) 3 4
  5. Signal sequence and keyword trap in silico for selection of full- length human cDNAs encoding secretion or membrane proteins from oligo- capped cDNA libraries. (PMID: 16303743) Otsuki T. … Isogai T. (DNA Res. 2005) 3 4

Products for GLMP Gene

Sources for GLMP Gene

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