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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GLIS1 Gene

protein-coding   GIFtS: 51
GCID: GC01M053971

GLIS Family Zinc Finger 1

Alzheimer's & Parkinson's Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
GLIS Family Zinc Finger 11 2
GLI-Similar 12 3
Zinc Finger Protein GLIS12

External Ids:    HGNC: 295251   Entrez Gene: 1489792   Ensembl: ENSG000001743327   OMIM: 6103785   UniProtKB: Q8NBF13   

Export aliases for GLIS1 gene to outside databases

Previous GC identifers: GC01M053683 GC01M052086


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GLIS1 Gene:
GLIS1 is a GLI (MIM 165220)-related Kruppel-like zinc finger protein that functions as an activator and repressor
of transcription (Kim et al., 2002 (PubMed 12042312)).(supplied by OMIM, Mar 2008)

GeneCards Summary for GLIS1 Gene: 
GLIS1 (GLIS family zinc finger 1) is a protein-coding gene. Diseases associated with GLIS1 include nephronophthisis, and parkinson's disease. GO annotations related to this gene include DNA binding and zinc ion binding. An important paralog of this gene is MTF1.

UniProtKB/Swiss-Prot: GLIS1_HUMAN, Q8NBF1
Function: Acts as both a repressor and activator of transcription. Binds to the consensus sequence
5'-GACCACCCAC-3' (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_032977.9  NC_018912.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for GLIS1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGLIS1 promoter sequence
   Search SABiosciences Chromatin IP Primers for GLIS1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GLIS1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p32.3   Ensembl cytogenetic band:  1p32.3   HGNC cytogenetic band: 1p32.3

GLIS1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GLIS1 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M053971:  view genomic region     (about GC identifiers)

Start:
53,971,906 bp from pter      End:
54,199,877 bp from pter
Size:
227,972 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: GLIS1_HUMAN, Q8NBF1 (See protein sequence)
Recommended Name: Zinc finger protein GLIS1  
Size: 620 amino acids; 65976 Da
Subcellular location: Nucleus (By similarity)
Sequence caution: Sequence=BAC04178.1; Type=Erroneous initiation;
Secondary accessions: Q2M3G9 Q8N9V9

Explore the universe of human proteins at neXtProt for GLIS1: NX_Q8NBF1

Explore proteomics data for GLIS1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8NBF1

  • GLIS1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    GLIS1 Protein Expression
    REFSEQ proteins: NP_671726.2  
    ENSEMBL proteins: 
     ENSP00000309653  

    Human Recombinant Protein Products for GLIS1: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Custom MassSpec 
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    Novus Biologicals GLIS1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for GLIS1 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS--

    GLIS1 for ontologies           About GeneDecksing



    GLIS1 Antibody Products: 
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    Cloud-Clone Corp. ELISAs for GLIS1 
    Cloud-Clone Corp. CLIAs for GLIS1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ZNF: Zinc fingers, C2H2-type

    3 InterPro protein domains:
     IPR015880 Znf_C2H2-like
     IPR013087 Znf_C2H2/integrase_DNA-bd
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q8NBF1

    ProtoNet protein and cluster: Q8NBF1

    UniProtKB/Swiss-Prot: GLIS1_HUMAN, Q8NBF1
    Similarity: Belongs to the GLI C2H2-type zinc-finger protein family
    Similarity: Contains 5 C2H2-type zinc fingers


    GLIS1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GLIS1_HUMAN, Q8NBF1
    Function: Acts as both a repressor and activator of transcription. Binds to the consensus sequence
    5'-GACCACCCAC-3' (By similarity)

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0008270zinc ion binding ----
    GO:0046872metal ion binding IEA--
         
    GLIS1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for GLIS1:
     Actin fiber cells  Increased cell number in S 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Glis1):
     limbs/digits/tail  nervous system  normal 

    GLIS1 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for GLIS1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for GLIS1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for GLIS1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for GLIS1 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GLIS1
    8/14 QIAGEN miScript miRNA Assays for microRNAs that regulate GLIS1 (see all 14):
    hsa-miR-3163 hsa-miR-4307 hsa-miR-4328 hsa-miR-409-3p hsa-miR-548e hsa-miR-578 hsa-miR-548o hsa-miR-548aa
    SwitchGear 3'UTR luciferase reporter plasmidGLIS1 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for GLIS1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GLIS1

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for GLIS1
    Sirion Biotech Customized adenovirus for overexpression of GLIS1

    Clone
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    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
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    OriGene ORF clones in mouse, rat for GLIS1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: GLIS1 (NM_147193)
    Sino Biological Human cDNA Clone for GLIS1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for GLIS1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GLIS1
    Sirion Biotech Customized lentivirus for stable overexpression of GLIS1 
                         Customized lentivirus expression plasmids for stable overexpression of GLIS1 

    Cell Line
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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GLIS1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GLIS1

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter ISS--
    GO:0006357regulation of transcription from RNA polymerase II promoter ----
    GO:0006366transcription from RNA polymerase II promoter ISS--
    GO:0045893positive regulation of transcription, DNA-dependent ----
    GO:0045944positive regulation of transcription from RNA polymerase II promoter ISS--

    GLIS1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for GLIS1

    Search CenterWatch for drugs/clinical trials and news about GLIS1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for GLIS1 gene: 
    NM_147193.2  

    Unigene Cluster for GLIS1:

    GLIS family zinc finger 1
    Hs.306691  [show with all ESTs]
    Unigene Representative Sequence: NM_147193
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000312233(uc001cvr.1)

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GLIS1
    8/14 QIAGEN miScript miRNA Assays for microRNAs that regulate GLIS1 (see all 14):
    hsa-miR-3163 hsa-miR-4307 hsa-miR-4328 hsa-miR-409-3p hsa-miR-548e hsa-miR-578 hsa-miR-548o hsa-miR-548aa
    SwitchGear 3'UTR luciferase reporter plasmidGLIS1 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for GLIS1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GLIS1
    Clone
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    OriGene ORF clones in mouse, rat for GLIS1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: GLIS1 (NM_147193)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for GLIS1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GLIS1
    Sirion Biotech Customized lentivirus for stable overexpression of GLIS1 
                         Customized lentivirus expression plasmids for stable overexpression of GLIS1 
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for GLIS1
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat GLIS1
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GLIS1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GLIS1

    Additional mRNA sequence: 

    AK090634.1 AK093474.1 BC101799.1 BC104911.1 

    1 DOTS entry:

    DT.100012675 

    15 AceView cDNA sequences:

    AX748150 AK093474 AA872588 BX283392 BX354527 NM_147193 BX354528 AK090634 
    BQ005715 BG747839 BX116059 AX746550 AI762232 N47961 N49172 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    GLIS1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACCCAGGGGA
    GLIS1 Expression
    About this image


    See GLIS1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for GLIS1

    SOURCE GeneReport for Unigene cluster: Hs.306691
        SABiosciences Custom PCR Arrays for GLIS1
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for GLIS1
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GLIS1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GLIS1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for GLIS1 gene from 5/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Glis11 , 5 GLIS family zinc finger 11, 5 83.98(n)1
    83.5(a)1
      4 (50.18 cM)5
    2305871  NM_147221.21  NP_671754.21 
     1074345915 
    chicken
    (Gallus gallus)
    Aves GLIS11 GLIS family zinc finger 1 65.11(n)
    66.44(a)
      424652  XM_422485.3  XP_422485.3 
    lizard
    (Anolis carolinensis)
    Reptilia GLIS16
    GLIS family zinc finger 1
    58(a)
    1 ↔ 1
    4(115519993-115665673)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003334061 zinc finger protein GLIS1-like 62.5(n)
    59.15(a)
      100333406  XM_002663103.2  XP_002663149.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta lmd6
    lame duck
    20(a)
    1 → many
    3R(18846944-18852435)


    ENSEMBL Gene Tree for GLIS1 (if available)
    TreeFam Gene Tree for GLIS1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for GLIS1 gene
    MTF12  ZIC32  ZNF4102  ZNF762  GLI12  ZIC22  ZIC12  GLIS22  
    GLI22  ZIC42  ZNF1432  GLIS32  ZIC52  GLI32  
    18/22 SIMAP similar genes for GLIS1 using alignment to 1 protein entry:     GLIS1_HUMAN(see all similar genes):
    GLIS3    kr-znf3    DKFZp686N0199    HZF16    ZNF    ZNF78L1
    ZFS-5    ZNF808    DKFZp686O1631    ZNF323    ZSCAN21    DKFZp666C237
    PLZF    ZFS-2    ZNF600    ZNF22    ZNF72    A-328A3.4

    GLIS1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/4600 SNPs in GLIS1 are shown (see all 4600)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1890013191,2
    --53971426(+) AGCCTA/TTGCCC 1 -- ds50010--------
    rs1817208981,2
    --53971492(+) GTTTTC/TTCTGT 1 -- ds50010--------
    rs1841524351,2
    --53971541(+) CCACCC/TGCTGA 1 -- ds50010--------
    rs1448174971,2
    --53971581(+) TCAGAC/TGGAGC 1 -- ds50010--------
    rs1164860571,2
    F--53971639(+) TCGCCG/ACACCC 1 -- ds50011Minor allele frequency- A:0.03WA 118
    rs1160963681,2
    F--53971697(+) CTGCAC/TAGTCC 1 -- ds50011Minor allele frequency- T:0.01WA 118
    rs115863601,2
    H--53971743(+) CATGGT/GGGGGG 1 -- ds50014Minor allele frequency- G:0.00NS EA 414
    rs171086421,2
    C,F,H--53971807(+) TTCTAC/TGCAGC 1 -- ds500114Minor allele frequency- T:0.08NA NS EA WA 1328
    rs120850161,2
    C,F,H--53971910(+) TCACAT/CCTCCT 1 -- ut31 trp313Minor allele frequency- C:0.05EA NS NA WA 1386
    rs728933081,2
    C--53971972(+) GGGAAC/TGGAAA 1 -- ut312Minor allele frequency- T:0.09WA 120

    HapMap Linkage Disequilibrium report for GLIS1 (53971906 - 54199877 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/22 variations for GLIS1 (see all 22):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2748286CNV Deletion23290073
    esv2748297CNV Deletion23290073
    esv2670230CNV Deletion23128226
    esv2313944CNV Deletion18987734
    esv1769487CNV Insertion17803354
    nsv899CNV Insertion18451855
    nsv509280CNV Insertion20534489
    nsv509269CNV Insertion20534489
    nsv512739CNV Insertion21212237
    nsv10162CNV Loss18304495

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing GLIS1
    DNA2.0 Custom Variant and Variant Library Synthesis for GLIS1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 610378    OMIM disorders: --

    2 diseases for GLIS1:    About MalaCards
    nephronophthisis    parkinson's disease

    1 disease from the University of Copenhagen DISEASES database for GLIS1:
    Nephronophthisis

    GLIS1 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015
    Genetic Association Database (GAD): GLIS1
    Human Genome Epidemiology (HuGE) Navigator: GLIS1 (1 document)

    Export disorders for GLIS1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for GLIS1 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with GLIS1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    2. Genome-wide association of lipid-lowering response to statins in combined study populations. (PubMed id 20339536)1, 4 Barber M.J....Krauss R.M. (2010)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. GLIS3, a novel member of the GLIS subfamily of Kruppel-like zinc finger proteins with repressor and activation functions. (PubMed id 14500813)1, 3 Kim Y.-S.... Jetten A.M. (2003)
    5. Identification of Glis1, a novel Gli-related, Kruppel-like zinc finger protein containing transactivation and repressor functions. (PubMed id 12042312)1, 3 Kim Y.S....Jetten A.M. (2002)
    6. Regulatory role for Kruppel-like zinc-finger protein Gli-similar 1 (Glis1) in PMA-treated and psoriatic epidermis. (PubMed id 16417217)1, 9 Nakanishi G....Jetten A.M. (2006)
    7. GLIS1 rs797906: an increased risk factor for late-onse t Parkinson's disease in the Han Chinese population. (PubMed id 22759478)1 Song W....Shang H.F. (2012)
    8. Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1. (PubMed id 21654807)1 Maekawa M....Yamanaka S. (2011)
    9. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    10. Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study. (PubMed id 17903301)4 Vasan R.S....Benjamin E.J. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Aliases
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    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 148979 HGNC: 29525 AceView: GLIS1 Ensembl:ENSG00000174332 euGenes: HUgn148979
    ECgene: GLIS1 H-InvDB: GLIS1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for GLIS1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for GLIS1 gene:
    Search GeneIP for patents involving GLIS1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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