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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

GLDN Gene

protein-coding GIFtS: 52
GCID: GC15P051633

gliomedin

(Previous name: collomin )
(Previous symbol: COLM)

Explore 3 diseases affiliated with
GLDN via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Gliomedin¹		UNC-112¹ ²
COLM¹ ² ³		Collomin¹
CLOM¹ ²		Colmedin¹
CRG-L2¹ ²		CRGL2² ⁵

External Ids:	HGNC: 29514¹	Entrez Gene: 342035²	Ensembl: ENSG00000186417⁷	OMIM: 608603⁵	UniProtKB: Q6ZMI3³

Export aliases for GLDN gene to outside databases

Previous GC identifers: GC15P049422 GC15P028463

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: GLDN_HUMAN, Q6ZMI3

Function: Plays a role in the formation of the nodes of Ranvier along myelinated axons. Probable NRCAM and

NFASC/neurofascin ligand which may provide a glial positional clue required for the proper molecular assembly of the

nodes of Ranvier (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000015.9 NC_018926.1 NT_010194.17

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the GLDN gene promoter:
AREB6 AhR PPAR-gamma1 AML1a COMP1 PPAR-gamma2 Evi-1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: GLDN promoter sequence

Search SABiosciences Chromatin IP Primers for GLDN

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GLDN

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q21.2 Ensembl cytogenetic band: 15q21.2 HGNC cytogenetic band: 15q15.3

GLDN Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GLDN gene location

GeneLoc information about chromosome 15 GeneLoc Exon Structure

GeneLoc location for GC15P051633: view genomic region (about GC identifiers)

Start:	51,633,713 bp from pter	End:	51,700,210 bp from pter
Size:	66,498 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: GLDN_HUMAN, Q6ZMI3 (See protein sequence)

Recommended Name: Gliomedin

Size: 551 amino acids; 58957 Da

Subunit: Interacts with NFASC/neurofascin and NRCAM (By similarity)

Subcellular location: Cell membrane; Single-pass type II membrane protein. Note=Localizes to the nodes of Ranvier (By

similarity)

Secondary accessions: Q6UXZ7 Q7Z359

Alternative splicing: 2 isoforms: Q6ZMI3-1 Q6ZMI3-2

Explore the universe of human proteins at neXtProt for GLDN: NX_Q6ZMI3

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q6ZMI3

GLDN Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_861454.2

ENSEMBL proteins:

ENSP00000335196 ENSP00000379681 ENSP00000453433

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
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	OriGene Purified Protein: GLDN Browse OriGene Protein Over-expression Lysates OriGene Custom Protein Services for GLDN
	GenScript Custom Purified and Recombinant Proteins Services for GLDN
	Novus Biologicals GLDN Protein
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for GLDN

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005581	collagen	IEA	--
GO:0005615	extracellular space	IEA	--
GO:0005886	plasma membrane	IEA	--
GO:0016021	integral to membrane	IEA	--

GLDN for ontologies About GeneDecksing

GLDN Antibody Products:

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	Novus Biologicals GLDN Antibodies
	Search for Antibodies for GLDN at Abcam
	Uscn Antibodies for GLDN
	ThermoFisher Antibodies for GLDN

Assay Products for GLDN:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for GLDN
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for GLDN

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

GLDN for domains About GeneDecksing

2 InterPro domains/families:

IPR003112 Olfac-like

IPR008160 Collagen

Graphical View of Domain Structure for InterPro Entry Q6ZMI3

ProtoNet protein and cluster: Q6ZMI3

3 Blocks protein families:

IPB003112 Olfactomedin-like

IPB008160 Collagen triple helix repeat

IPB008161 Collagen helix repeat

UniProtKB/Swiss-Prot: GLDN_HUMAN, Q6ZMI3

Domain: The olfactomedin-like domain mediates NFASC/neurofascin and NRCAM binding (By similarity)

Similarity: Contains 2 collagen-like domains

Similarity: Contains 1 olfactomedin-like domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: GLDN_HUMAN, Q6ZMI3

Function: Plays a role in the formation of the nodes of Ranvier along myelinated axons. Probable NRCAM and

NFASC/neurofascin ligand which may provide a glial positional clue required for the proper molecular assembly of the

nodes of Ranvier (By similarity)

miRNA Products:		OriGene 3'-UTR Clone: GLDN Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GLDN
		8/32 QIAGEN miScript miRNA Assays for microRNAs that regulate GLDN (see all 32):
		hsa-miR-3607-5p hsa-miR-607 hsa-miR-3660 hsa-miR-106a hsa-miR-2110 hsa-miR-764 hsa-miR-29b-1* hsa-miR-1304

		SwitchGear 3'UTR luciferase reporter plasmid: GLDN 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GLDN (see all 7) OriGene shRNA RFP: GLDN OriGene siRNA: GLDN
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GLDN

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for GLDN

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GLDN (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GLDN OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: GLDN (NM_181789)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for GLDN
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GLDN

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for GLDN
		Search LifeMap BioReagents cell lines for GLDN

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GLDN

2 GenomeRNAi human phenotypes for GLDN:

G2 arrest

Increased S DNA content

Animal Models:
Mouse knock-out Gldn^tm1Pele for GLDN
3 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Gldn):

behavior/neurological

mortality/aging

nervous system

GLDN for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for GLDN

1 Interacting protein for GLDN (Q6ZMI3³) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
NFASC	O94856³	I2D: score=1

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007399	nervous system development	IEA	--
GO:0030154	cell differentiation	IEA	--

GLDN for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for GLDN
Search CenterWatch for drugs/clinical trials and news about GLDN

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for GLDN gene:

NM_181789.2

Unigene Cluster for GLDN:

Gliomedin

Hs.526441 [show with all ESTs]

Unigene Representative Sequence: NM_181789

9 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000335449(uc002aba.3) ENST00000560215 ENST00000558286 ENST00000560690

ENST00000559317 ENST00000464150(uc010bez.1) ENST00000396399(uc002abb.3)

ENST00000561194 ENST00000558426

miRNA Products:		OriGene 3'-UTR Clone: GLDN Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GLDN
		8/32 QIAGEN miScript miRNA Assays for microRNAs that regulate GLDN (see all 32):
		hsa-miR-3607-5p hsa-miR-607 hsa-miR-3660 hsa-miR-106a hsa-miR-2110 hsa-miR-764 hsa-miR-29b-1* hsa-miR-1304

		SwitchGear 3'UTR luciferase reporter plasmid: GLDN 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GLDN (see all 7) OriGene shRNA RFP: GLDN OriGene siRNA: GLDN
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GLDN

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GLDN (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GLDN OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: GLDN (NM_181789)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for GLDN
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GLDN

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GLDN Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat GLDN
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GLDN
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GLDN

Additional cDNA sequence:

AK095128.1 AK172756.1 AK308933.1 AK310755.1 AY358144.1 BC113397.1 BC113399.1 BX538105.1

5 DOTS entries:

DT.91974209 DT.406569 DT.101963424 DT.40112906 DT.121054945

24/43 AceView cDNA sequences (see all 43):

BX337184 CR590325 BX101284 BI756736 BX387035 AI199825 AA969362 AW148870

BI755831 AI186284 BX324705 F35834 BQ879885 BI551391 BX324704 AK095128

F26898 AK023623 NM_181789 AK172756 AU138192 BG623119 BX538105 AY358144

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for GLDN About this scheme

ExUns:	1a	·	1b	·	1c	^	2	^	3a	·	3b	^	4a	·	4b	^	5	^	6	^	7	^	8	^	9	^	10
SP1:
SP2:									-
SP3:					-		-		-
SP4:							-		-
SP5:

ECgene alternative splicing isoforms for GLDN

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

GLDN expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTCACCACTG

About this image

GLDN expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Adipose

Thoracic Perivascular Adipose

Adipose

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

PureStem™ progenitor W8 (Embryonic Progenitor Cell)

HyStem+BMP4-induced MEL2 cells (HyStem+BMP4 inductio...)

Bone

See GLDN Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for GLDN

SOURCE GeneReport for Unigene cluster: Hs.526441

UniProtKB/Swiss-Prot: GLDN_HUMAN, Q6ZMI3

Tissue specificity: Specifically expressed in spinal cord, brain, placenta and sciatic nerve. More abundant in

peripheral than central nervous system

SABiosciences Custom PCR Arrays for GLDN

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GLDN Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat GLDN
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GLDN
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GLDN

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GLDN

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for GLDN gene from 5/15 species (see all 15) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	GLDN¹	gliomedin	67.13(n) 62.2(a)		427523 XM_425097.3 XP_425097.3
lizard (Anolis carolinensis)	Reptilia	-- --	--	53(a) 16(a)	1 ↔ 1 possible ortholog	GL343330.1(454567-455082) GL343330.1(464147-489707)
zebrafish (Danio rerio)	Actinopterygii	colm¹	collomin	55.51(n) 48.28(a)		572018 NM_001080165.2 NP_001073634.1
fruit fly (Drosophila melanogaster)	Insecta	CG6867¹	CG6867	47.9(n) 35.99(a)		32782 NM_133034.5 NP_573262.2
worm (Caenorhabditis elegans)	Secernentea	cof-2¹	Protein COF-2	43.81(n) 26.93(a)		183582 NM_059403.2 NP_491804.2

ENSEMBL Gene Tree for GLDN (if available)
TreeFam Gene Tree for GLDN (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for GLDN gene

OLFM3² OLFML3² OLFML2A² OLFM2² OLFM1² OLFM4² MYOC² OLFML2B²

OLFML1²

11 SIMAP similar genes for GLDN using alignment to 3 protein entries: GLDN_HUMAN (see all proteins):

OLFM1 COL5A1 SCARA5 COL4A3 MARCO COL13A1

COLEC11 COL24A1 COL25A1 DKFZp434L081 COL6A5

GLDN for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 15 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs1071955^1,2	C,F,H,	--	51632812(-)	`TGGCTC/GTGCTT`	1	--	us2k¹		12		NA WA CSA EA	553
rs111869510^1,2	C,	--	51632861(+)	`TCTCTG/AAGGAG`	1	--	us2k¹		1		NA	2
rs149559370^1,2		--	51632866(+)	`GAGGAA/GACTCA`	1	--	us2k¹		0	--	--	--	--
rs80226513^1,2	F,	--	51633010(+)	`CCCAGC/ATCTCC`	1	--	us2k¹		1		WA	118
rs11630919^1,2	C,F,H,	--	51633061(+)	`ATGCTC/GAAAGC`	1	--	us2k¹		12		NA WA CSA EA	379
rs144237110^1,2		--	51633213(+)	`AAGGAC/TGAGTC`	1	--	us2k¹		0	--	--	--	--
rs79934502^1,2	F,	--	51633262(+)	`GGGTGG/ACCTTT`	1	--	us2k¹		1		WA	118
rs144989335^1,2	C,	--	51633301(+)	`GCCCC-/TATCCA`	1	--	us2k¹		0	--	--	--	--
rs139952202^1,2		--	51633381(+)	`TGATGC/TGCAGC`	1	--	us2k¹		0	--	--	--	--
rs11631118^1,2	C,F,A,H,	--	51633396(+)	`TGCTCG/AGGCCA`	1	--	us2k¹		13		NS NA WA CSA EA	835

HapMap Linkage Disequilibrium report for GLDN (51633713 - 51700210 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for GLDN
3 CNVs: 3081 8798 3963

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GLDN

DNA2.0 Custom Variant and Variant Library Synthesis for GLDN

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

GLDN for disorders           About GeneDecksing

OMIM gene information: 608603    OMIM disorders: --

3 diseases for GLDN:    About MalaCards

demyelinating polyneuropathy neuritis polyneuropathy

1 disease from the University of Copenhagen DISEASES database for GLDN:

Demyelinating polyneuropathy

Export disorders for GLDN gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for GLDN gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with GLDN)

Utopia: connect your pdf to the dynamic
world of online information

Gliomedin mediates Schwann cell-axon interaction and the molecular assembly of the nodes of Ranvier. (PubMed id 16039564)^{1, 2, 3, 9} Eshed Y.... Peles E. (2005)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Identification and characterization of CRG-L2, a new marker for liver tumor development. (PubMed id 12642876)^{1, 3} Graveel C.R....Farnham P.J. (2003)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2} Clark H.F.... Gray A.M. (2003)
Nodal proteins are target antigens in Guillain-Barre s yndrome. (PubMed id 22462667)¹ Devaux J.J....Yuki N. (2012)
Fibronectin type III-like domains of neurofascin-186 p rotein mediate gliomedin binding and its clustering at the developing nodes of R anvier. (PubMed id 22009740)¹ Labasque M....Faivre-Sarrailh C. (2011)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Secreted gliomedin is a perinodal matrix component of peripheral nerves. (PubMed id 17485493)⁹ Eshed Y....Peles E. (2007)
Cleavage and oligomerization of gliomedin, a transmembrane collagen required for node of ranvier formation. (PubMed id 17293346)⁹ Maertens B....Koch M. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 342035	HGNC: 29514	AceView: COLM	Ensembl:ENSG00000186417	euGenes: HUgn342035
ECgene: GLDN	H-InvDB: GLDN

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for GLDN	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for GLDN	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for GLDN gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for GLDN gene:
Search GeneIP for patents involving GLDN

Licensable Technologies for GLDN gene:

Weizmann Institute:

Modulation of Ion-Channel Clustering by Gliomedin

GeneCards and IP:
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GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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