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GLDN Gene

protein-coding   GIFtS: 54
GCID: GC15P051633

Gliomedin

(Previous name: collomin)
(Previous symbol: COLM)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
gliomedin1 2     CLOM2
COLM1 2 3     CRG-L22
collomin1 2     UNC-1122
CRGL22 5     colmedin2

External Ids:    HGNC: 295141   Entrez Gene: 3420352   Ensembl: ENSG000001864177   OMIM: 6086035   UniProtKB: Q6ZMI33   

Export aliases for GLDN gene to outside databases

Previous GC identifers: GC15P049422 GC15P028463


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for GLDN Gene:
GLDN (gliomedin) is a protein-coding gene. GO annotations related to this gene include protein binding involved in heterotypic cell-cell adhesion. An important paralog of this gene is OLFM3.

UniProtKB/Swiss-Prot: GLDN_HUMAN, Q6ZMI3
Function: Plays a role in the formation of the nodes of Ranvier along myelinated axons. Probable NRCAM and
NFASC/neurofascin ligand which may provide a glial positional clue required for the proper molecular assembly of
the nodes of Ranvier (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000015.9  NT_010194.18  NC_018926.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the GLDN gene promoter:
         AREB6   AhR   PPAR-gamma1   AML1a   COMP1   PPAR-gamma2   Evi-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGLDN promoter sequence
   Search Chromatin IP Primers for GLDN

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat GLDN


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q21.2   Ensembl cytogenetic band:  15q21.2   HGNC cytogenetic band: 15q15.3

GLDN Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GLDN gene location

GeneLoc information about chromosome 15         GeneLoc Exon Structure

GeneLoc location for GC15P051633:  view genomic region     (about GC identifiers)

Start:
51,633,713 bp from pter      End:
51,700,210 bp from pter
Size:
66,498 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: GLDN_HUMAN, Q6ZMI3 (See protein sequence)
Recommended Name: Gliomedin  
Size: 551 amino acids; 58957 Da
Subunit: Interacts with NFASC/neurofascin and NRCAM (By similarity)
Secondary accessions: Q6UXZ7 Q7Z359
Alternative splicing: 2 isoforms:  Q6ZMI3-1   Q6ZMI3-2   

Explore the universe of human proteins at neXtProt for GLDN: NX_Q6ZMI3

Explore proteomics data for GLDN at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn130, Asn329, Asn357, Asn378, Asn464
  • Modification sites at PhosphoSitePlus

  • See GLDN Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_861454.2  
    ENSEMBL proteins: 
     ENSP00000335196   ENSP00000379681   ENSP00000453433  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR003112 Olfac-like
     IPR008160 Collagen

    Graphical View of Domain Structure for InterPro Entry Q6ZMI3

    ProtoNet protein and cluster: Q6ZMI3

    3 Blocks protein domains:
    IPB003112 Olfactomedin-like
    IPB008160 Collagen triple helix repeat
    IPB008161 Collagen helix repeat


    UniProtKB/Swiss-Prot: GLDN_HUMAN, Q6ZMI3
    Domain: The olfactomedin-like domain mediates NFASC/neurofascin and NRCAM binding (By similarity)
    Similarity: Contains 2 collagen-like domains
    Similarity: Contains 1 olfactomedin-like domain


    Find genes that share domains with GLDN           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: GLDN_HUMAN, Q6ZMI3
    Function: Plays a role in the formation of the nodes of Ranvier along myelinated axons. Probable NRCAM and
    NFASC/neurofascin ligand which may provide a glial positional clue required for the proper molecular assembly of
    the nodes of Ranvier (By similarity)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0086080protein binding involved in heterotypic cell-cell adhesion IEA--
         
    Find genes that share ontologies with GLDN           About GenesLikeMe


    Phenotypes:
         2 GenomeRNAi human phenotypes for GLDN:
     G2 arrest  Increased S DNA content 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Gldn):
     behavior/neurological  mortality/aging  nervous system 

    Find genes that share phenotypes with GLDN           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Gldntm1Pele for GLDN

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for GLDN
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for GLDN
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for GLDN

    miRNA
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    miRTarBase miRNAs that target GLDN:
    hsa-mir-7-5p (MIRT025832)

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    Selected qRT-PCR Assays for microRNAs that regulate GLDN (see all 32):
    hsa-miR-3607-5p hsa-miR-607 hsa-miR-3660 hsa-miR-106a hsa-miR-2110 hsa-miR-764 hsa-miR-29b-1* hsa-miR-1304
    SwitchGear 3'UTR luciferase reporter plasmidGLDN 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat GLDN

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    GenScript: all cDNA clones in your preferred vector: GLDN (NM_181789)
    Sino Biological Human cDNA Clone for GLDN
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GLDN

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GLDN


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    GLDN_HUMAN, Q6ZMI3: Cell membrane; Single-pass type II membrane protein. Note=Localizes to the nodes of Ranvier
    (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane5
    extracellular3
    cytosol1
    endoplasmic reticulum1
    mitochondrion1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005581collagen IEA--
    GO:0005615extracellular space IEA--
    GO:0005886plasma membrane IEA--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with GLDN           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for GLDN
    Interactions:

        Search GeneGlobe Interaction Network for GLDN

    1 Interacting protein for GLDN (Q6ZMI33) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NFASCO948563I2D: score=1 
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0032528microvillus organization IEA--
    GO:0034113heterotypic cell-cell adhesion ----
    GO:0045162clustering of voltage-gated sodium channels IEA--

    Find genes that share ontologies with GLDN           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for GLDN



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for GLDN gene: 
    NM_181789.2  

    Unigene Cluster for GLDN:

    Gliomedin
    Hs.526441  [show with all ESTs]
    Unigene Representative Sequence: NM_181789
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000335449(uc002aba.3) ENST00000560215 ENST00000558286 ENST00000560690
    ENST00000559317 ENST00000464150(uc010bez.1) ENST00000396399(uc002abb.3)
    ENST00000561194 ENST00000558426
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate GLDN (see all 32):
    hsa-miR-3607-5p hsa-miR-607 hsa-miR-3660 hsa-miR-106a hsa-miR-2110 hsa-miR-764 hsa-miR-29b-1* hsa-miR-1304
    SwitchGear 3'UTR luciferase reporter plasmidGLDN 3' UTR sequence
    Inhib. RNA
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    GenScript: all cDNA clones in your preferred vector: GLDN (NM_181789)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for GLDN
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GLDN
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for GLDN
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat GLDN
      QuantiTect SYBR Green Assays in human, mouse, rat GLDN
      QuantiFast Probe-based Assays in human, mouse, rat GLDN

    Additional mRNA sequence: 

    AK095128.1 AK172756.1 AK308933.1 AK310755.1 AY358144.1 BC113397.1 BC113399.1 BX538105.1 

    5 DOTS entries:

    DT.91974209  DT.406569  DT.101963424  DT.40112906  DT.121054945 

    Selected AceView cDNA sequences (see all 43):

    AI199825 BX387035 CR590325 AA969362 BX101284 BI756736 BX337184 BI755831 
    AU138192 AK172756 AK023623 F26898 BQ879885 F35834 BX324705 BG623119 
    BX538105 AW148870 AI186284 NM_181789 AK095128 BX324704 BI551391 AY358144 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for GLDN    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10
    SP1:                                                                                    
    SP2:                          -                                                         
    SP3:              -     -     -                                                         
    SP4:                    -     -                                                         
    SP5:                                                                                    


    ECgene alternative splicing isoforms for GLDN

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    GLDN expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CTCACCACTG
    GLDN Expression
    About this image


    GLDN expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Bone (Muscoskeletal System)    fully expand to see all 2 entries
             HyStem+TGFbeta3+GDF5-induced MEL2 cells
     
     Cartilage (Muscoskeletal System)
             HyStem+TGFbeta3+GDF5-induced MEL2 cells
     
     Placenta (Extraembryonic Tissues)
    GLDN Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    GLDN Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.526441

    UniProtKB/Swiss-Prot: GLDN_HUMAN, Q6ZMI3
    Tissue specificity: Specifically expressed in spinal cord, brain, placenta and sciatic nerve. More abundant in
    peripheral than central nervous system

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for GLDN gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gldn1 , 5 gliomedin1, 5 85.95(n)1
    86.86(a)1
      9 (29.52 cM)5
    2353791  NM_177350.51  NP_796324.11 
     542864865 
    chicken
    (Gallus gallus)
    Aves GLDN1 gliomedin 66.73(n)
    62.09(a)
      427523  XM_425097.4  XP_425097.4 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    53(a)
    43(a)
    1 ↔ many
    1 ↔ many
    GL343330.1(454567-455082)
    GL343330.1(464147-489802)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia gldn1 gliomedin 62.21(n)
    59.46(a)
      100493767  XM_002936337.2  XP_002936383.2 
    zebrafish
    (Danio rerio)
    Actinopterygii gldn1 gliomedin 53.18(n)
    44.11(a)
      572018  NM_001080165.2  NP_001073634.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG68676
    --
    17(a)
    1 → many
    X(17917903-17922294)
    worm
    (Caenorhabditis elegans)
    Secernentea unc-1226
    cof-26
    Protein COF-2 (cof-2) mRNA, complete cds
    21(a)
    20(a)
    many ↔ many
    many ↔ many
    I(14872162-14875378) WBGene00006845
    I(6250571-6252821) WBGene00000583


    ENSEMBL Gene Tree for GLDN (if available)
    TreeFam Gene Tree for GLDN (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for GLDN gene
    OLFM32  OLFML32  OLFML2A2  OLFM12  OLFM42  OLFM22  OLFML2B2  MYOC2  
    OLFML12  
    10 SIMAP similar genes for GLDN using alignment to 3 protein entries:     GLDN_HUMAN (see all proteins):
    OLFM1    COL5A1    COL4A3    MARCO    COL13A1    COLEC11
    COL24A1    COL25A1    COL3A1    DKFZp434L081

    Find genes that share paralogs with GLDN           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for GLDN (see all 1612)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 15 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs10719551,2
    C,F,H--51632812(-) TGGCTC/GTGCTT 1 -- us2k112Minor allele frequency- G:0.22NA WA CSA EA 553
    rs1118695101,2
    C,F--51632861(+) TCTCTG/AAGGAG 1 -- us2k11Minor allele frequency- A:0.50NA 2
    rs1495593701,2
    --51632866(+) GAGGAA/GACTCA 1 -- us2k10--------
    rs802265131,2
    C,F--51633010(+) CCCAGC/ATCTCC 1 -- us2k11Minor allele frequency- A:0.09WA 118
    rs116309191,2
    C,F,H--51633061(+) ATGCTC/GAAAGC 1 -- us2k112Minor allele frequency- G:0.22NA WA CSA EA 379
    rs1442371101,2
    --51633213(+) AAGGAC/TGAGTC 1 -- us2k10--------
    rs799345021,2
    F--51633262(+) GGGTGG/ACCTTT 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1449893351,2
    C--51633301(+) GCCCC-/TATCCA 1 -- us2k10--------
    rs1399522021,2
    --51633381(+) TGATGC/TGCAGC 1 -- us2k10--------
    rs116311181,2
    C,F,A,H--51633396(+) TGCTCG/AGGCCA 1 -- us2k113Minor allele frequency- A:0.25NS NA WA CSA EA 835

    HapMap Linkage Disequilibrium report for GLDN (51633713 - 51700210 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for GLDN:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv94788CNV Insertion16902084
    nsv904216CNV Loss21882294
    esv34532CNV Gain17911159
    nsv471243CNV Gain18288195
    nsv904215CNV Gain21882294
    nsv904217CNV Gain21882294
    dgv747e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing GLDN
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 608603    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for GLDN:
    Demyelinating polyneuropathy

    Find genes that share disorders with GLDN           About GenesLikeMe

    Genetic Association Database (GAD): GLDN

    Export disorders for GLDN gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for GLDN gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with GLDN)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Gliomedin mediates Schwann cell-axon interaction and the molecular assembly of the nodes of Ranvier. (PubMed id 16039564)1, 2, 3, 9 Eshed Y.... Peles E. (Neuron 2005)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Identification and characterization of CRG-L2, a new marker for liver tumor development. (PubMed id 12642876)1, 3 Graveel C.R....Farnham P.J. (Oncogene 2003)
    4. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    5. Nodal proteins are target antigens in Guillain-BarrAc syndrome. (PubMed id 22462667)1 Devaux J.J....Yuki N. (J. Peripher. Nerv. Syst. 2012)
    6. Fibronectin type III-like domains of neurofascin-186 protein mediate gliomedin binding and its clustering at the developing nodes of Ranvier. (PubMed id 22009740)1 Labasque M....Faivre-Sarrailh C. (J. Biol. Chem. 2011)
    7. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (BMC Med. Genet. 2007)
    8. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. Secreted gliomedin is a perinodal matrix component of peripheral nerves. (PubMed id 17485493)9 Eshed Y....Peles E. (J. Cell Biol. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 342035 HGNC: 29514 AceView: COLM Ensembl:ENSG00000186417 euGenes: HUgn342035
    ECgene: GLDN H-InvDB: GLDN

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for GLDN Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for GLDN Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for GLDN gene:
    Search GeneIP for patents involving GLDN

    Licensable Technologies for GLDN gene:
    Weizmann Institute:Modulation of Ion-Channel Clustering by Gliomedin
    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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