Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

GK5 Gene

protein-coding GIFtS: 50
GCID: GC03M141876

glycerol kinase 5 (putative)

Explore 1 disease affiliated with
GK5 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Glycerol Kinase 5 (Putative)¹ ²		EC 2.7.1.30³ ⁸
Glycerokinase 5² ³		MGC40579¹
ATP:Glycerol 3-Phosphotransferase 5² ³		Putative Glycerol Kinase 5²
GK 5² ³

External Ids:	HGNC: 28635¹	Entrez Gene: 256356²	Ensembl: ENSG00000175066⁷	UniProtKB: Q6ZS86³

ORGUL members:
	NONCODE:n409152

Export aliases for GK5 gene to outside databases

Previous GC identifers: GC03M143359 GC03M139249

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000003.11 NC_018914.1 NT_005612.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the GK5 gene promoter:
HOXA9 HOXA9B COUP MyoD Egr-4 Meis-1b COUP-TF Pax-4a Meis-1 ATF6
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for GK5

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GK5

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q23 Ensembl cytogenetic band: 3q23 HGNC cytogenetic band: 3q23

GK5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GK5 gene location

GeneLoc information about chromosome 3 GeneLoc Exon Structure

GeneLoc location for GC03M141876: view genomic region (about GC identifiers)

Start:	141,876,369 bp from pter	End:	141,944,449 bp from pter
Size:	68,081 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: GLPK5_HUMAN, Q6ZS86 (See protein sequence)

Recommended Name: Putative glycerol kinase 5

Size: 529 amino acids; 59156 Da

Secondary accessions: B2R9I2 D3DNG2 Q8N2A7 Q8N5E6

Alternative splicing: 3 isoforms: Q6ZS86-1 Q6ZS86-2 Q6ZS86-3

Explore the universe of human proteins at neXtProt for GK5: NX_Q6ZS86

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q6ZS86

4/9 DME Specific Peptides for GK5 (Q6ZS86) (see all 9)

GLAVGFW

AFRNKQL

IFGVPIP

IRCHVYD

GK5 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_001034636.1

ENSEMBL proteins:

ENSP00000420312 ENSP00000419031 ENSP00000418001 ENSP00000417153 ENSP00000420593

ENSP00000419651 ENSP00000418239 ENSP00000440860

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: GK5 OriGene Protein Over-expression Lysate: GK5 OriGene Custom Protein Services for GK5
	GenScript Custom Purified and Recombinant Proteins Services for GK5
	Novus Biologicals GK5 Proteins Novus Biologicals GK5 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for GK5

GK5 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	OriGene Antibodies: GK5 OriGene Custom Antibody Services for GK5
	GenScript Custom Superior Antibodies Services for GK5
	Novus Biologicals GK5 Antibodies
	Search for Antibodies for GK5 at Abcam
	Uscn Antibodies for GK5
	Search ThermoFisher Antibodies for GK5

Assay Products for GK5:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for GK5
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for GK5

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

GK5 for domains About GeneDecksing

3 InterPro domains/families:

IPR018485 Carb_kinase_FGGY_C

IPR018483 Carb_kinase_FGGY_CS

IPR018484 Carb_kinase_FGGY_N

Graphical View of Domain Structure for InterPro Entry Q6ZS86

ProtoNet protein and cluster: Q6ZS86

1 Blocks protein family: IPB000577 Carbohydrate kinase

UniProtKB/Swiss-Prot: GLPK5_HUMAN, Q6ZS86

Similarity: Belongs to the FGGY kinase family

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: GLPK5_HUMAN, Q6ZS86

Catalytic activity: ATP + glycerol = ADP + sn-glycerol 3-phosphate

Enzyme Number (IUBMB): EC 2.7.1.30¹ ²

miRNA Products:		OriGene 3'-UTR Clone: GK5 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GK5
		8/76 QIAGEN miScript miRNA Assays for microRNAs that regulate GK5 (see all 76):
		hsa-miR-607 hsa-miR-1304 hsa-miR-29a* hsa-miR-3148 hsa-miR-3622a-5p hsa-miR-34c-5p hsa-miR-186* hsa-miR-3065-5p

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GK5 (see all 4) OriGene shRNA RFP: GK5 OriGene siRNA: GK5
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GK5

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for GK5

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GK5 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GK5 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: GK5 (NM_001039547)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for GK5
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GK5

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for GK5
		Search LifeMap BioReagents cell lines for GK5

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GK5

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004370	glycerol kinase activity	IEA	--
GO:0005524	ATP binding	IEA	--
GO:0016773	phosphotransferase activity, alcohol group as acceptor	--	--

GK5 for ontologies About GeneDecksing

2 GenomeRNAi human phenotypes for GK5:

Decreased POU5F1-GFP protein e

Increased Salmonella enterica

Animal Models:
1 MGI phenotypic allele

for Gk5 (no phenotypes)

GK5 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

glycerol degradation I

glycerol degradation I

1.00

1 BioSystems Pathway for GK5

glycerol degradation I

UniProtKB/Swiss-Prot: GLPK5_HUMAN, Q6ZS86

Pathway: Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol:

step 1/1

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for GK5

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

2 Interacting proteins for GK5 (ENSP00000418001⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
UBC	ENSP00000344818⁴	STRING: ENSP00000344818
ELAVL1	ENSP00000385269⁴	STRING: ENSP00000385269

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005975	carbohydrate metabolic process	--	--
GO:0019563	glycerol catabolic process	IEA	--

GK5 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for GK5

2 HMDB Compounds for GK5 About this table

Compound	Synonyms	CAS #	PubMed Ids
Glycerol	1,2,3-Trihydroxypropane (see all 22)	56-81-5	--
Glycerol 3-phosphate	1-(dihydrogen phosphate) Glycerol (see all 37)	57-03-4	--

Search CenterWatch for drugs/clinical trials and news about GK5 / GLPK5

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for GK5 gene (2 alternative transcripts):

NM_152776.1 NM_001039547.2

Unigene Clusters for GK5:

Glycerol kinase 5 (putative)

Hs.135904 [show with all ESTs], Hs.744309 [show with all ESTs]

Unigene Representative Sequences: AK130469, NR_033289

13 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000492097(uc010hus.2) ENST00000480757 ENST00000460515(uc003eup.1)

ENST00000392993(uc003euq.2) ENST00000463349 ENST00000486459 ENST00000460630

ENST00000466685 ENST00000460544 ENST00000487672(uc010hut.2) ENST00000472759

ENST00000489085 ENST00000544571

miRNA Products:		OriGene 3'-UTR Clone: GK5 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GK5
		8/76 QIAGEN miScript miRNA Assays for microRNAs that regulate GK5 (see all 76):
		hsa-miR-607 hsa-miR-1304 hsa-miR-29a* hsa-miR-3148 hsa-miR-3622a-5p hsa-miR-34c-5p hsa-miR-186* hsa-miR-3065-5p

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GK5 (see all 4) OriGene shRNA RFP: GK5 OriGene siRNA: GK5
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GK5

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GK5 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GK5 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: GK5 (NM_001039547)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for GK5
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GK5

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GK5 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat GK5
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GK5
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GK5

Additional cDNA sequence:

AK090901.1 AK127641.1 AK310761.1 AK313792.1 BX648359.1 NR_033289.1

4 DOTS entries:

DT.75116731 DT.40233186 DT.75189915 DT.75165086

24/64 AceView cDNA sequences (see all 64):

AW769016 BM685050 AW299704 AI250691 AL567263 CR598125 AA648374 AX746669

BG697446 CA412196 BU170345 AK127641 AK090901 AA347327 AI866260 BM997156

BQ632763 BX505625 BE875664 BX648359 BM782446 BC032470 BX385143 BX509538

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for GK5 About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11	^	12	^	13	^	14	^	15	^	16	^	17	^	18	^	19
SP1:											-												-		-
SP2:													-		-		-		-		-		-
SP3:

ECgene alternative splicing isoforms for GK5

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

GK5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTTCACTTT

About this image

GK5 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Ovary

Antral Follicle

Mature Granulosa Cells

Ovary

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See GK5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for GK5

SOURCE GeneReport for Unigene clusters: Hs.135904 Hs.744309

SABiosciences Custom PCR Arrays for GK5

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GK5 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat GK5
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GK5
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GK5

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GK5

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the last universal common ancestor (LUCA).

Orthologs for GK5 gene from 8/31 species (see all 31) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	GK5¹	glycerol kinase 5 (putative)	69.78(n) 64.02(a)		424779 NM_001031306.1 NP_001026477.1
lizard (Anolis carolinensis)	Reptilia	GK5⁶ --	--	68(a) 29(a)	1 ↔ 1 possible ortholog	3(21955380-21978549) 3(129116465-129146022)
zebrafish (Danio rerio)	Actinopterygii	wufc06f04²	Transcribed sequence with weak similarity to protein more	74.11(n)		CK126414.1
fruit fly (Drosophila melanogaster)	Insecta	CG1271¹	CG1271	47.71(n) 41.18(a)		38364 NM_139506.2 NP_647763.1
worm (Caenorhabditis elegans)	Secernentea	C55B6.1¹	Protein C55B6.1	49.64(n) 37.82(a)		180984 NM_001029332.2 NP_001024503.1
thale cress (Arabidopsis thaliana)	eudicotyledons	NHO1⁶	glycerol kinase	29(a)	possible ortholog	1(30246745-30249305)
rice (Oryza sativa)	Liliopsida	--	FGGY family of carbohydrate kinases, putative, exp...	30(a)	possible ortholog	4(32770597-32774831)
E. coli (Escherichia coli)	Gamma proteobacteria	glpK⁶	glycerol kinase	32(a)	possible ortholog	Chromosome(4113737-4115245)

ENSEMBL Gene Tree for GK5 (if available)
TreeFam Gene Tree for GK5 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for GK5 gene

GK² GK2²

3 SIMAP similar genes for GK5 using alignment to 5 protein entries: GLPK5_HUMAN (see all proteins):

GK GK3P GK2

GK5 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 3 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs183096036^1,2		--	141875954(+)	`AAAAAA/GTACAC`	2	--	int¹		0	--	--	--	--
rs111582922^1,2		--	141875955(+)	`AAAAAT/CACACG`	2	--	int¹		2		CSA WA	120
rs188375731^1,2		--	141875957(+)	`AAATAA/CACGAA`	2	--	int¹		0	--	--	--	--
rs191747206^1,2		--	141875965(+)	`GAATAC/TTCAAT`	2	--	int¹		0	--	--	--	--
rs114737148^1,2	F,	--	141876015(+)	`AAAACC/TCATTC`	2	--	int¹		1		WA	118
rs138758737^1,2		--	141876063(+)	`AGCAAC/TGTCAG`	2	--	int¹		0	--	--	--	--
rs184710996^1,2		--	141876172(+)	`CCTCTC/TCCTTT`	2	--	int¹		0	--	--	--	--
rs76244822^1,2	C,F,	--	141876357(+)	`AGCAAA/GTAACA`	2	--	int¹		1		WA	118
rs187353736^1,2		--	141876755(+)	`ACAAGA/TGCTAT`	2	--	nc-transcript-variantut3¹		0	--	--	--	--
rs151313486^1,2		--	141876787(+)	`TTGTT-/GT TGTTGTTTTT`	2	--	nc-transcript-variantut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for GK5 (141876369 - 141944449 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 6 variations for GK5
6 CNVs: 8431 50949 8430 53086 2476 3451

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GK5

DNA2.0 Custom Variant and Variant Library Synthesis for GK5

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

GK5 for disorders About GeneDecksing

1 disease for GK5: About MalaCards

alcoholism

Export disorders for GK5 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for GK5 gene integrated from 9 sources:
(articles sorted by number of sources associating them with GK5)

Utopia: connect your pdf to the dynamic
world of online information

Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)^{1, 3} Strausberg R.L....Marra M.A. (2002)
Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)¹ Kim W....Gygi S.P. (2011)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)¹ Abdelmohsen K....Gorospe M. (2009)
The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)² Muzny D.M....Gibbs R.A. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 256356	HGNC: 28635	AceView: MGC40579	Ensembl:ENSG00000175066	euGenes: HUgn256356
ECgene: GK5	H-InvDB: GK5

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for GK5	Pharmacogenomics, SNPs, Pathways

Intellectual Property for GK5 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for GK5 gene:
Search GeneIP for patents involving GK5

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	OriGene Antibodies for GK5		OriGene shRNA RFP for GK5
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for GK5		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for GK5
	OriGene Protein Over-expression Lysate for GK5		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for GK5		OriGene 3'-UTR Clone for GK5
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for GK5		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for GK5
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	OriGene Purified Protein for GK5		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for GK5		OriGene Custom Protein Services for GK5
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat GK5
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GK5
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GK5
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GK5
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GK5
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GK5

	GenScript Custom Purified and Recombinant Proteins Services for GK5		GenScript cDNA clones with any tag delivered in your preferred vector for GK5
	GenScript Custom Assay Services for GK5		GenScript Custom Superior Antibodies Services for GK5
	GenScript Custom overexpressing Cell Line Services for GK5		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in GK5 promoter
	Search Chromatin IP Primers for GK5
	RT² qPCR Primer Assay in human, mouse, rat GK5
	Search GNC Networks for GK5
	SABiosciences Custom PCR Arrays for GK5

Search Tocris compounds for GK5

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	GK5 antibodies
	GK5 proteins
	GK5 lysates

	Search for Antibodies for GK5 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for GK5
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

GK5 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for GK5

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GK5

	Browse SwitchGear 3'UTR luciferase reporter plasmids for GK5
	Browse SwitchGear Promoter luciferase reporter plasmids for GK5

Search ThermoFisher Antibodies for GK5

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GK5

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes GK5 gene at Home site.

hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4

Advanced Search

Export list of displayed genes

GK5 Gene

glycerol kinase 5 (putative)

Aliases
for GK5 gene

Summaries
for GK5 gene

Genomic Views
for GK5 gene

Proteins
for GK5 gene

Protein Domains /
Families
for GK5 gene

Function
for GK5 gene

Pathways & Interactions
for GK5 gene

Drugs & Compounds
for GK5 gene

Transcripts
for GK5 gene

Expression
for GK5 gene

Orthologs
for GK5 gene

Paralogs
for GK5 gene

Genomic Variants
for GK5 gene

Disorders / Diseases
for GK5 gene

Publications
for GK5 gene

External Searches for GK5 gene

Genome Databases showing GK5 gene

Other Databases showing GK5 gene

Specialized Databases showing GK5 gene

Intellectual Property
for GK5 gene

Products
for GK5 gene

View Random Gene

Advanced Search

Export list of displayed genes

GK5 Gene

glycerol kinase 5 (putative)

Aliasesfor GK5 gene

Summariesfor GK5 gene

Genomic Viewsfor GK5 gene

Proteinsfor GK5 gene

Protein Domains /Familiesfor GK5 gene

Functionfor GK5 gene

Pathways & Interactionsfor GK5 gene

Drugs & Compoundsfor GK5 gene

Transcriptsfor GK5 gene

Expression for GK5 gene

Orthologsfor GK5 gene

Paralogsfor GK5 gene

Genomic Variantsfor GK5 gene

Disorders / Diseasesfor GK5 gene

Publicationsfor GK5 gene

External Searches for GK5 gene

Genome Databases showing GK5 gene

Other Databases showing GK5 gene

Specialized Databases showing GK5 gene

Intellectual Propertyfor GK5 gene

Productsfor GK5 gene

View Random Gene

Aliases
for GK5 gene

Summaries
for GK5 gene

Genomic Views
for GK5 gene

Proteins
for GK5 gene

Protein Domains /
Families
for GK5 gene

Function
for GK5 gene

Pathways & Interactions
for GK5 gene

Drugs & Compounds
for GK5 gene

Transcripts
for GK5 gene

Expression
for GK5 gene

Orthologs
for GK5 gene

Paralogs
for GK5 gene

Genomic Variants
for GK5 gene

Disorders / Diseases
for GK5 gene

Publications
for GK5 gene

Intellectual Property
for GK5 gene

Products
for GK5 gene