Aliases for GK Gene
External Ids for GK Gene
Previous GeneCards Identifiers for GK Gene
The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]
GeneCards Summary for GK Gene
GK (Glycerol Kinase) is a Protein Coding gene. Diseases associated with GK include Glycerol Kinase Deficiency and Glycerol Kinase Deficiency, Adult Form. Among its related pathways are glycerol degradation and Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha). GO annotations related to this gene include kinase activity and glycerol kinase activity. An important paralog of this gene is GK2.
UniProtKB/Swiss-Prot for GK Gene
Key enzyme in the regulation of glycerol uptake and metabolism.