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GJB7 Gene

protein-coding   GIFtS: 47
GCID: GC06M087992

Gap Junction Protein, Beta 7, 25kDa

(Previous names: gap junction protein, beta 7)
  Search for GJB7
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Gap Junction Protein, Beta 7, 25kDa1 2     connexin-252
CX252 3 5     connexin252
Connexin 251 2     Gap Junction Beta-7 Protein2
Gap Junction Protein, Beta 71     Connexin-253
bA136M9.12     Cx253

External Ids:    HGNC: 166901   Entrez Gene: 3755192   Ensembl: ENSG000001644117   OMIM: 6119215   UniProtKB: Q6PEY03   

Export aliases for GJB7 gene to outside databases

Previous GC identifers: GC06M087989 GC06M087988 GC06M088049 GC06M085209


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for GJB7 Gene:
Connexins, such as GJB7, are involved in the formation of gap junctions, intercellular conduits that directly
connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels,
each of which contains 6 connexin subunits (Sohl et al., 2003 (PubMed 12881038)).(supplied by OMIM, Mar 2008)

GeneCards Summary for GJB7 Gene:
GJB7 (gap junction protein, beta 7, 25kDa) is a protein-coding gene. An important paralog of this gene is GJB3.

UniProtKB/Swiss-Prot: CXB7_HUMAN, Q6PEY0
Function: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons,
through which materials of low MW diffuse from one cell to a neighboring cell (By similarity)

summary for GJB7 Gene:
Gap channels (also known as gap junctions) are specalized cell-cell contacts between almost all eukaryotic
cells that provide direct intracellular communication. Generally, gap channels allow the passive diffusion
of molecules up to 1 kDa which includes nutrients, small metabolites (e.g. glucose), ions (K+, Ca2+) and
second messengers (IP3, cAMP and cGMP). Gap channels allow electrical and biochemical coupling between cells
and in excitable tissues, such as neurons and the heart, enables the generation of synchronized and rapid
responses. Structurally, gap channels are composed of two hemichannels called 'connexons', which themselves
are formed from six connexin molecules. Homo- and heteromeric combinations are seen, which exhibit distinct
permeability, selectivity and functional properties. Pannexins are related to connexins and can also form
gap junctions. However, their expression is limited to the brain. Furthermore, in nonchordate animals a
family of proteins called innexins form these channels. Gap channels are regulated through
post-translational modifications of the C'-terminal cytoplasmic tail and phosphorylation modulates assembly
and their physiological properties. They are continuously synthesized and degraded, allowing tissues to
rapidly adapt to changing environmental conditions. Connexins play a key role in many physiological
processes including cardiac and smooth muscle contraction, regulation of neuronal excitability, epithelial
electrolyte transport and keratinocyte differentiation. Mutations in connexin genes are associated with
human diseases including sensorineural deafness, a variety of skin disorders, peripheral neuropathy and
cardiovascular disease.

Gene Wiki entry for GJB7 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NT_025741.16  NC_018917.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the GJB7 gene promoter:
         Pbx1a   MyoD   MIF-1   FAC1   POU2F1   POU2F1b   FOXJ2 (long isoform)   POU2F1a   POU2F1c   FOXJ2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGJB7 promoter sequence
   Search Chromatin IP Primers for GJB7

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat GJB7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q15   Ensembl cytogenetic band:  6q15   HGNC cytogenetic band: 6q15

GJB7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GJB7 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M087992:  view genomic region     (about GC identifiers)

Start:
87,992,696 bp from pter      End:
88,038,996 bp from pter
Size:
46,301 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CXB7_HUMAN, Q6PEY0 (See protein sequence)
Recommended Name: Gap junction beta-7 protein  
Size: 223 amino acids; 25860 Da
Subunit: A connexon is composed of a hexamer of connexins (By similarity)
Secondary accessions: B3KXL0 Q96KP0

Explore the universe of human proteins at neXtProt for GJB7: NX_Q6PEY0

Explore proteomics data for GJB7 at MOPED


See GJB7 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_940970.1  
ENSEMBL proteins: 
 ENSP00000435355   ENSP00000358589   ENSP00000296882  
Reactome Protein details: Q6PEY0

GJB7 Human Recombinant Protein Products:

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Search eBioscience for ELISAs for GJB7 


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
GJ: Ion channels / Gap junction proteins (connexins)

IUPHAR Guide to PHARMACOLOGY protein family classification: Cx25
Connexins and Pannexins

4 InterPro protein domains:
 IPR000500 Connexin
 IPR019570 Connexin_CCC
 IPR013092 Connexin_N
 IPR017990 Connexin_CS

Graphical View of Domain Structure for InterPro Entry Q6PEY0

ProtoNet protein and cluster: Q6PEY0

1 Blocks protein domain: IPB013092 Connexin

UniProtKB/Swiss-Prot: CXB7_HUMAN, Q6PEY0
Similarity: Belongs to the connexin family. Beta-type (group I) subfamily


Find genes that share domains with GJB7           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: CXB7_HUMAN, Q6PEY0
Function: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons,
through which materials of low MW diffuse from one cell to a neighboring cell (By similarity)

Phenotypes:
     1 GenomeRNAi human phenotype for GJB7:

 Increased circadian period len 

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for GJB7
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miRNA
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Selected qRT-PCR Assays for microRNAs that regulate GJB7 (see all 10):
hsa-miR-520d-5p hsa-miR-769-5p hsa-miR-516b hsa-miR-597 hsa-miR-581 hsa-miR-3920 hsa-miR-145 hsa-miR-524-5p
SwitchGear 3'UTR luciferase reporter plasmidGJB7 3' UTR sequence
Inhib. RNA
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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
CXB7_HUMAN, Q6PEY0: Cell membrane; Multi-pass membrane protein (By similarity). Cell junction, gap junction (By
similarity)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
plasma membrane5

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005922connexon complex IEA--
GO:0016021integral component of membrane IEA--

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(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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SuperPaths for GJB7 About    
See pathways by source

SuperPathContained pathways About
1Gap junction trafficking
Gap junction trafficking0.93
Gap junction assembly0.00
Gap junction trafficking and regulation0.93
2Clathrin derived vesicle budding
Membrane Trafficking0.32
3Signaling in Gap Junctions
Signaling in Gap Junctions0.31
4Hypothetical Network for Drug Addiction
Hypothetical Network for Drug Addiction


Find genes that share SuperPaths with GJB7           About GenesLikeMe

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways

1 Downloadable PowerPoint Slide of GeneGlobe Pathway Central Maps for GJB7
    Signaling in Gap Junctions

1 BioSystems Pathway for GJB7
    Hypothetical Network for Drug Addiction

1 Reactome Pathway for GJB7
    Gap junction assembly


    Pathway & Disease-focused RT2 Profiler PCR Array including GJB7: 
          Gap Junctions in human mouse rat

Interactions:

    Search GeneGlobe Interaction Network for GJB7

STRING Interaction Network Preview (showing 5 interactants - click image to see 19)

Selected Interacting proteins for GJB7 (ENSP000002968824) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
InteractantInteraction Details
GeneCardExternal ID(s)
GJA1ENSP000002825614STRING: ENSP00000282561
GJA10ENSP000003583584STRING: ENSP00000358358
GJA3ENSP000002411254STRING: ENSP00000241125
GJA4ENSP000003436764STRING: ENSP00000343676
GJA5ENSP000002713484STRING: ENSP00000271348
About this table

Gene Ontology (GO): 1 biological process term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0007154cell communication IEA--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Compounds for GJB7 available from Tocris Bioscience    About this table
CompoundAction CAS #
Gap 27Selective gap junction blocker[198284-64-9]
Scrambled 10Panx Scrambled version of 10Panx (Cat. No. 3348), Panx-1 mimetic inhibitory peptide [1315378-72-3]
Carbenoxolone disodiumGap junction blocker. Also inhibitor of 11 beta-hydroxysteroid dehydrogenase[7421-40-1]
10PanxPanx-1 mimetic inhibitory peptide; blocks pannexin-1 gap junctions[955091-53-9]

4 IUPHAR Ligands for GJB7 (Cx25)    About this table
LigandTypeActionAffinityPubmed IDs
flufenamic acid
InhibitorNone--
octanol
InhibitorNone--
Ca2+
InhibitorNone--
carbenoxolone
InhibitorNone--



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for GJB7 gene: 
NM_198568.2  

Unigene Cluster for GJB7:

Gap junction protein, beta 7, 25kDa
Hs.146727  [show with all ESTs]
Unigene Representative Sequence: NM_198568
4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000525899(uc003plo.2) ENST00000369576 ENST00000442973 ENST00000296882

miRNA
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Selected qRT-PCR Assays for microRNAs that regulate GJB7 (see all 10):
hsa-miR-520d-5p hsa-miR-769-5p hsa-miR-516b hsa-miR-597 hsa-miR-581 hsa-miR-3920 hsa-miR-145 hsa-miR-524-5p
SwitchGear 3'UTR luciferase reporter plasmidGJB7 3' UTR sequence
Inhib. RNA
Products:
     
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Predesigned siRNA for gene silencing in human, mouse, rat GJB7
Clone
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GenScript: all cDNA clones in your preferred vector: GJB7 (NM_198568)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for GJB7
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GJB7
Primer
Products:
    
OriGene qPCR primer pairs and template standards for GJB7
OriGene qSTAR qPCR primer pairs in human, mouse for GJB7
Pre-validated RT2 qPCR Primer Assay in human, mouse / rat GJB7
  QuantiTect SYBR Green Assays in human, mouse, rat GJB7
  QuantiFast Probe-based Assays in human, mouse, rat GJB7

Additional mRNA sequence: 

AK127554.1 BC057813.1 

1 DOTS entry:

DT.100686383 

14 AceView cDNA sequences:

AK127554 BU679354 AA749214 BM976147 CB991778 BQ028678 NM_198568 CB990421 
BC057813 CA311893 AW264672 AI014718 CB991210 AA702791 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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GJB7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: AGGGTAGAGA
GJB7 Expression
About this image

GJB7 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

GJB7 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.146727

UniProtKB/Swiss-Prot: CXB7_HUMAN, Q6PEY0
Tissue specificity: Weakly expressed in placenta

    Pathway & Disease-focused RT2 Profiler PCR Array including GJB7: 
          Gap Junctions in human mouse rat

Primer
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OriGene qPCR primer pairs and template standards for GJB7
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QuantiFast Probe-based Assays in human, mouse, rat GJB7
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GJB7

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for GJB7 gene from Selected species (see all 7)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
dog
(Canis familiaris)
Mammalia GJB71 gap junction protein, beta 7, 25kDa 89.8(n)
89.95(a)
  100687173  XM_005627602.1  XP_005627659.1 
African clawed frog
(Xenopus laevis)
Amphibia BC055269.12   -- 73.83(n)    BC055269.1 
zebrafish
(Danio rerio)
Actinopterygii cx28.81 connexin 28.8 61.11(n)
59.8(a)
  566668  NM_001045239.2  NP_001038704.2 


ENSEMBL Gene Tree for GJB7 (if available)
TreeFam Gene Tree for GJB7 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for GJB7 gene
GJB32  GJA102  GJD32  GJB62  GJB42  GJB22  GJA42  GJB52  
GJA12  GJC12  GJC22  GJA52  GJD22  GJA32  GJA92  GJA82  
GJB12  
17 SIMAP similar genes for GJB7 using alignment to 2 protein entries:     CXB7_HUMAN (see all proteins):
GJB5    GJB4    GJB2    GJB3    GJB1    GJC1
GJB6    GJA3    GJA8    GJA1    GJC3    GJA4
GJA10    GJA5    GJA9    GJD3    GJD4

Find genes that share paralogs with GJB7           About GenesLikeMe



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for GJB7 (see all 765)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 6 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs121969741,2
C,F--87992242(+) ATTACC/TTGCAT 1 -- int11Minor allele frequency- T:0.03NA 120
rs1494573751,2
--87992256(+) TGCAGA/GCTAGA 1 -- int10--------
rs1831253721,2
--87992376(+) TGTCTA/GGAACA 1 -- int10--------
rs22404591,2
C,F,A,H--87992408(+) TGACCA/GCTGCT 1 -- int118Minor allele frequency- G:0.35NS EA NA WA CSA 974
rs22404601,2
C,F,A,H--87992435(+) GACCAT/CGTAAT 1 -- int114Minor allele frequency- C:0.46NA WA CSA EA 602
rs168789071,2
C,F--87992462(+) ATTGCG/ACATGA 1 -- int16Minor allele frequency- A:0.02NA CSA WA 262
rs1430496211,2
--87992587(+) ATTTCA/TTAGCC 1 -- int10--------
rs1482163241,2
--87992726(+) ATTCTA/GAAGAA 1 -- ut310--------
rs1412192711,2
C--87992734(+) GAAATA/GTACAT 1 -- ut310--------
rs32142441,2
C--87992797(+) ATAGA-/AAAGT 
        
AAAGA
1 -- ut310--------

HapMap Linkage Disequilibrium report for GJB7 (87992696 - 88038996 bp)

Structural Variations
     Database of Genomic Variants (DGV) 6 variations for GJB7:    About this table    
Variant IDTypeSubtypePubMed ID
esv2667119CNV Deletion23128226
nsv507346CNV Insertion20534489
nsv349083CNV Loss16902084
nsv5386CNV Loss18451855
nsv823771CNV Loss20364138
dgv1991e1CNV Complex17122850

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing GJB7
DNA2.0 Custom Variant and Variant Library Synthesis for GJB7

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 611921    OMIM disorders: --


Find genes that share disorders with GJB7           About GenesLikeMe


Export disorders for GJB7 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for GJB7 gene integrated from 10 sources:
(articles sorted by number of sources associating them with GJB7)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  2. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
  3. Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues. (PubMed id 12881038)1, 2 Soehl G.... Willecke K. (Cell Commun. Adhes. 2003)
  4. Structural and functional diversity of connexin genes in the mouse and human genome. (PubMed id 12108537)1, 2 Willecke K.... Soehl G. (Biol. Chem. 2002)
  5. Cloning and functional expression of a novel human connexin-25 gene. (PubMed id 12064583)2, 9 Bondarev I.... Bertram J.S. (Cell Commun. Adhes. 2001)
  6. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
  7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (Nat. Genet. 2004)
  8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  9. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (Genome Res. 1996)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
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  Query String
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 375519 HGNC: 16690 AceView: GJB7 Ensembl:ENSG00000164411 euGenes: HUgn375519
ECgene: GJB7 H-InvDB: GJB7

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for GJB7 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for GJB7 gene:
Search GeneIP for patents involving GJB7

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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