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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

GJA10 Gene

protein-coding   GIFtS: 49
GCID: GC06P090604

Gap Junction Protein, Alpha 10, 62kDa

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Gap Junction Protein, Alpha 10, 62kDa1 2     connexin-622
CX622 3 5     Gap Junction Alpha-10 Protein2
Connexin 621 2     Connexin-623
RP11-63K6.62     Cx623

External Ids:    HGNC: 169951   Entrez Gene: 846942   Ensembl: ENSG000001353557   OMIM: 6119245   UniProtKB: Q969M23   

Export aliases for GJA10 gene to outside databases

Previous GC identifers: GC01M039264 GC01M038347 GC01M038803 GC01M038742 GC01M038743 GC01M038998 GC01M039009 GC01M039102 GC06P090661 GC06P087823


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GJA10 Gene:
Connexins, such as GJA10, are involved in the formation of gap junctions, intercellular conduits that directly
connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels,
each of which contains 6 connexin subunits (Sohl et al., 2003 (PubMed 12881038)).(supplied by OMIM, Mar 2008)

GeneCards Summary for GJA10 Gene: 
GJA10 (gap junction protein, alpha 10, 62kDa) is a protein-coding gene. Diseases associated with GJA10 include peripheral neuropathy, and neuropathy, and among its related super-pathways are Gap junction assembly and Transmission across Electrical Synapses . GO annotations related to this gene include gap junction channel activity. An important paralog of this gene is GJB3.

UniProtKB/Swiss-Prot: CXA10_HUMAN, Q969M2
Function: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons,
through which materials of low MW diffuse from one cell to a neighboring cell. Involved in tracer coupling
between horizontal cells of the retina. May play a role in the regulation of horizontal cell patterning (By
similarity)

summary for GJA10 Gene:
Gap channels (also known as gap junctions) are specalized cell-cell contacts between almost all eukaryotic
cells that provide direct intracellular communication. Generally, gap channels allow the passive diffusion
of molecules up to 1 kDa which includes nutrients, small metabolites (e.g. glucose), ions (K+, Ca2+) and
second messengers (IP3, cAMP and cGMP). Gap channels allow electrical and biochemical coupling between cells
and in excitable tissues, such as neurons and the heart, enables the generation of synchronized and rapid
responses. Structurally, gap channels are composed of two hemichannels called 'connexons', which themselves
are formed from six connexin molecules. Homo- and heteromeric combinations are seen, which exhibit distinct
permeability, selectivity and functional properties. Pannexins are related to connexins and can also form
gap junctions. However, their expression is limited to the brain. Furthermore, in nonchordate animals a
family of proteins called innexins form these channels. Gap channels are regulated through
post-translational modifications of the C'-terminal cytoplasmic tail and phosphorylation modulates assembly
and their physiological properties. They are continuously synthesized and degraded, allowing tissues to
rapidly adapt to changing environmental conditions. Connexins play a key role in many physiological
processes including cardiac and smooth muscle contraction, regulation of neuronal excitability, epithelial
electrolyte transport and keratinocyte differentiation. Mutations in connexin genes are associated with
human diseases including sensorineural deafness, a variety of skin disorders, peripheral neuropathy and
cardiovascular disease.

Gene Wiki entry for GJA10 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.2  NT_007299.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the GJA10 gene promoter:
         AP-1   Pbx1a   Nkx2-2   STAT5A   Egr-4   Egr-2   IRF-2   IRF-7A   ZID   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidGJA10 promoter sequence
   Search SABiosciences Chromatin IP Primers for GJA10

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GJA10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q15-q16   Ensembl cytogenetic band:  6q15   HGNC cytogenetic band: 6q15-q16

GJA10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GJA10 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P090604:  view genomic region     (about GC identifiers)

Start:
90,604,188 bp from pter      End:
90,605,839 bp from pter
Size:
1,652 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CXA10_HUMAN, Q969M2 (See protein sequence)
Recommended Name: Gap junction alpha-10 protein  
Size: 543 amino acids; 61872 Da
Subunit: A connexon is composed of a hexamer of connexins (By similarity)
Subcellular location: Cell membrane; Multi-pass membrane protein (By similarity). Cell junction, gap junction (By
similarity)

Explore the universe of human proteins at neXtProt for GJA10: NX_Q969M2

Explore proteomics data for GJA10 at MOPED 

GJA10 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

GJA10 Protein Expression

REFSEQ proteins: NP_115991.1  
ENSEMBL proteins: 
 ENSP00000358358  
Reactome Protein details: Q969M2
Human Recombinant Protein Products for GJA10: 
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Browse ProSpec Recombinant Proteins
Browse Proteins at Cloud-Clone Corp. 

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005886plasma membrane TAS--
GO:0005921gap junction ----
GO:0005922connexon complex IEA--
GO:0016021integral to membrane IEA--

GJA10 for ontologies           About GeneDecksing



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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
HGNC Gene Families: 
GJ: Ion channels / Gap junction proteins (connexins)

IUPHAR Guide to PHARMACOLOGY protein family classification: Cx62 
Connexins and Pannexins

4 InterPro protein domains:
 IPR000500 Connexin
 IPR019570 Connexin_CCC
 IPR013092 Connexin_N
 IPR017990 Connexin_CS

Graphical View of Domain Structure for InterPro Entry Q969M2

ProtoNet protein and cluster: Q969M2

1 Blocks protein domain: IPB013092 Connexin

UniProtKB/Swiss-Prot: CXA10_HUMAN, Q969M2
Similarity: Belongs to the connexin family. Alpha-type (group II) subfamily


GJA10 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: CXA10_HUMAN, Q969M2
Function: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons,
through which materials of low MW diffuse from one cell to a neighboring cell. Involved in tracer coupling
between horizontal cells of the retina. May play a role in the regulation of horizontal cell patterning (By
similarity)

     Genatlas biochemistry entry for GJA10:
gap junction protein alpha 10,31.1kB,(connexin 31.1),expressed in epidermis,mouse Cx 31.1 homolog,monomer of the
connexon (six subunits)

     Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005243gap junction channel activity TAS--
     
GJA10 for ontologies           About GeneDecksing


Phenotypes:
     3 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Gja10):
 nervous system  no phenotypic analysis  vision/eye 

GJA10 for phenotypes           About GeneDecksing

Animal Models:
   inGenious Targeting Laboratory - Custom generated mouse model solutions for GJA10 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for GJA10

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for GJA10 
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for GJA10 

miRNA
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QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GJA10
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Inhib. RNA
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Gene Editing
Products:
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Sirion Biotech Customized adenovirus for overexpression of GJA10

Clone
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OriGene clones in human, mouse for GJA10 (see all 6)
OriGene ORF clones in mouse, rat for GJA10
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: GJA10 (NM_032602)
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Cell Line
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Search LifeMap BioReagents cell lines for GJA10
In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GJA10


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for GJA10 About                                                                                                See pathways by source

SuperPathContained pathways About
1Gap junction trafficking
Gap junction trafficking0.74
Gap junction trafficking and regulation0.70
Gap junction assembly0.74
2Electric Transmission Across Gap Junctions
Transmission across Electrical Synapses 1.00
Electric Transmission Across Gap Junctions1.00
3Transmission across Chemical Synapses
Neuronal System0.67
4Membrane Trafficking
Membrane Trafficking0.32

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways


5/7        Reactome Pathways for GJA10 (see all 7)
    Gap junction assembly
Gap junction trafficking
Membrane Trafficking
Transmission across Electrical Synapses
Electric Transmission Across Gap Junctions



GJA10 for pathways           About GeneDecksing

Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for GJA10

STRING Interaction Network Preview (showing 5 interactants - click image to see 19)

5/19 Interacting proteins for GJA10 (ENSP000003583584) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
InteractantInteraction Details
GeneCardExternal ID(s)
GJA1ENSP000002825614STRING: ENSP00000282561
GJA3ENSP000002411254STRING: ENSP00000241125
GJA4ENSP000003436764STRING: ENSP00000343676
GJA5ENSP000002713484STRING: ENSP00000271348
GJA8ENSP000002409864STRING: ENSP00000240986
About this table

Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0007268synaptic transmission TAS--
GO:0007276gamete generation IEA--
GO:0007416synapse assembly IEA--
GO:0009416response to light stimulus ----
GO:0050908detection of light stimulus involved in visual perception IEA--

GJA10 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Compounds for GJA10 available from Tocris Bioscience    About this table
CompoundAction CAS #
Gap 27Selective gap junction blocker[198284-64-9]
Scrambled 10Panx Scrambled version of 10Panx (Cat. No. 3348), Panx-1 mimetic inhibitory peptide [1315378-72-3]
Carbenoxolone disodiumGap junction blocker. Also inhibitor of 11 beta-hydroxysteroid dehydrogenase[7421-40-1]
10PanxPanx-1 mimetic inhibitory peptide; blocks pannexin-1 gap junctions[955091-53-9]

4 IUPHAR Ligands for GJA10 (Cx62)    About this table 
LigandTypeActionAffinityPubmed IDs
flufenamic acid
InhibitorNone--
octanol
InhibitorNone--
Ca2+
InhibitorNone--
carbenoxolone
InhibitorNone--

Search CenterWatch for drugs/clinical trials and news about GJA10 / CXA10

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for GJA10 gene: 
NM_032602.1  

Unigene Cluster for GJA10:

Gap junction protein, alpha 10, 62kDa
Hs.334499
Unigene Representative Sequence: AF296766
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000369352(uc011eaa.2)
miRNA
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Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for GJA10
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GJA10
Clone
Products:
     
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OriGene ORF clones in mouse, rat for GJA10
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GenScript: all cDNA clones in your preferred vector: GJA10 (NM_032602)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for GJA10
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GJA10
Sirion Biotech Customized lentivirus for stable overexpression of GJA10 
                     Customized lentivirus expression plasmids for stable overexpression of GJA10 
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for GJA10
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat GJA10
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GJA10
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GJA10

Additional mRNA sequence: AF296766.1 

1 DOTS entry:

DT.95232530 

2 AceView cDNA sequences:

NM_032602 AF296766 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

GJA10 expression in normal human tissues (normalized intensities)      GJA10 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GAACTATCAC
GJA10 Expression
About this image


GJA10 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database 
 5/1 selected tissues (see all 1) fully expand
 
 Eye (Sensory Organs)
         Mature Horizontal Cells Inner Nuclear Layer

See GJA10 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for GJA10

SOURCE GeneReport for Unigene cluster: Hs.334499

UniProtKB/Swiss-Prot: CXA10_HUMAN, Q969M2
Tissue specificity: Expressed in skeletal muscle and heart

    SABiosciences Custom PCR Arrays for GJA10
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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GJA10

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for GJA10 gene from 4/9 species (see all 9)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Gja101 , 5 gap junction protein, alpha 101, 5 83.85(n)1
81.44(a)1
  4 (14.25 cM)5
146101  NM_010289.21  NP_034419.21 
 326006445 
chicken
(Gallus gallus)
Aves GJA101 gap junction protein, alpha 10, 62kDa 60.53(n)
59.09(a)
  771878  XM_001235096.1  XP_001235097.1 
lizard
(Anolis carolinensis)
Reptilia GJA106
Gap junction protein
79(a)
1 ↔ 1
1(174622429-174623154)
zebrafish
(Danio rerio)
Actinopterygii cx52.71 connexin 52.7 56.19(n)
53.53(a)
  572278  NM_001113502.1  NP_001106974.1 


ENSEMBL Gene Tree for GJA10 (if available)
TreeFam Gene Tree for GJA10 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for GJA10 gene
GJB32  GJB62  GJB42  GJB22  GJB72  GJA42  GJB52  GJA12  
GJC12  GJC22  GJA52  GJD22  GJA32  GJA92  GJA82  GJB12  
11 SIMAP similar genes for GJA10 using alignment to 1 protein entry:     CXA10_HUMAN:
GJA3    GJA4    GJA1    GJA9    GJA5    GJB5
GJB4    GJC1    GJA8    GJB7    GJB3

GJA10 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/129 SNPs in GJA10 are shown (see all 129)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 6 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs177643081,2
C,F,H--90602268(+) TTTTAT/CAGGTT 1 -- us2k113Minor allele frequency- C:0.09NA NS EA CSA 1103
rs1149284431,2
C,F--90602455(+) GCATGA/TCCTTG 1 -- us2k12Minor allele frequency- T:0.10WA NA 238
rs77747231,2
C,F--90602535(+) ataggC/Tgcaca 1 -- us2k12Minor allele frequency- T:0.07WA 120
rs77746041,2
C,F--90602556(+) tggctA/Catttt 1 -- us2k12Minor allele frequency- C:0.23WA NA 122
rs2922431,2
C,F,A--90602625(-) gatgaC/Tgaggt 1 -- us2k14Minor allele frequency- T:0.29WA NA CSA 7
rs2922421,2
C,A--90602631(-) CGGGCA/GGATGA 1 -- us2k10--------
rs93626971,2
C--90602680(+) CACTGC/TGCCCA 1 -- us2k11Minor allele frequency- T:0.50CSA 2
rs177077381,2
C,F,H--90602735(+) TGGAAG/AGAGAG 1 -- us2k1 tfbs3 trp320Minor allele frequency- A:0.10NA NS EA WA 2368
rs1385104081,2
--90602739(+) AGGAGA/GGAATT 1 -- us2k10--------
rs803195011,2
F--90602766(+) TTTTTA/G/TGAAAC 1 -- us2k11NA 2

HapMap Linkage Disequilibrium report for GJA10 (90604188 - 90605839 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for GJA10: --
SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing GJA10
DNA2.0 Custom Variant and Variant Library Synthesis for GJA10

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 611924    OMIM disorders: --

3 diseases for GJA10:    About MalaCards
peripheral neuropathy    neuropathy    neuronitis


GJA10 for disorders           About GeneDecksing

Genetic Association Database (GAD): GJA10
Human Genome Epidemiology (HuGE) Navigator: GJA10 (3 documents)

Export disorders for GJA10 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for GJA10 gene integrated from 9 sources:
(articles sorted by number of sources associating them with GJA10)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Association between genetic variants in VEGF, ERCC3 a nd occupational benzene haematotoxicity. (PubMed id 19773279)1, 4 Hosgood H.D....Lan Q. (2009)
  2. Expression profiles of the novel human connexin genes hCx30.2, hCx40.1, and hCx62 differ from their putative mouse orthologues. (PubMed id 12881038)1, 2 Soehl G.... Willecke K. (2003)
  3. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)2 Mungall A.J.... Beck S. (2003)
  4. Structural and functional diversity of connexin genes in the mouse and human genome. (PubMed id 12108537)2 Willecke K.... Soehl G. (2002)
  5. Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)

(in PubMed, OMIM, and NCBI Bookshelf)
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 84694 HGNC: 16995 AceView: CX62 Ensembl:ENSG00000135355 euGenes: HUgn84694
ECgene: GJA10 H-InvDB: GJA10

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for GJA10 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
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Patent Information for GJA10 gene:
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