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Aliases for GJA1 Gene

Aliases for GJA1 Gene

  • Gap Junction Protein Alpha 1 2 3 5
  • Gap Junction Protein, Alpha 1, 43kDa 2 3
  • Gap Junction 43 KDa Heart Protein 3 4
  • Connexin 43 2 3
  • Connexin-43 3 4
  • CX43 3 4
  • GJAL 3 4
  • Gap Junction Protein, Alpha 1, 43kDa (Connexin 43) 2
  • Oculodentodigital Dysplasia (Syndactyly Type III) 2
  • Gap Junction Protein, Alpha-Like 2
  • AVSD3 3
  • HLHS1 3
  • PPKCA 3
  • CMDR 3
  • EKVP 3
  • ODDD 3
  • HSS 3

External Ids for GJA1 Gene

Previous HGNC Symbols for GJA1 Gene

  • ODDD
  • GJAL

Previous GeneCards Identifiers for GJA1 Gene

  • GC06P121527
  • GC06P121714
  • GC06P121737
  • GC06P121798
  • GC06P119340
  • GC06P121756

Summaries for GJA1 Gene

Entrez Gene Summary for GJA1 Gene

  • This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations. [provided by RefSeq, May 2014]

GeneCards Summary for GJA1 Gene

GJA1 (Gap Junction Protein Alpha 1) is a Protein Coding gene. Diseases associated with GJA1 include oculodentodigital dysplasia and syndactyly, type iii. Among its related pathways are Blood-Brain Barrier and Immune Cell Transmigration: Pathways Overview and Antiarrhythmic Pathway, Pharmacodynamics. GO annotations related to this gene include receptor binding and protein domain specific binding. An important paralog of this gene is GJC2.

UniProtKB/Swiss-Prot for GJA1 Gene

  • Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity). May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles (By similarity).

Tocris Summary for GJA1 Gene

  • Gap channels (gap junctions) are specialized cell-cell contacts that provide direct intracellular communication. They allow passive diffusion of molecules up to 1 kDa, including nutrients, metabolites (glucose), ions (K+, Ca2+) and second messengers (IP3, cAMP).

Gene Wiki entry for GJA1 Gene

No data available for PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GJA1 Gene

Genomics for GJA1 Gene

Regulatory Elements for GJA1 Gene

Promoters for GJA1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around GJA1 on UCSC Golden Path with GeneCards custom track

Genomic Location for GJA1 Gene

Chromosome:
6
Start:
121,435,577 bp from pter
End:
121,449,744 bp from pter
Size:
14,168 bases
Orientation:
Plus strand

Genomic View for GJA1 Gene

Genes around GJA1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GJA1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GJA1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GJA1 Gene

Proteins for GJA1 Gene

  • Protein details for GJA1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P17302-CXA1_HUMAN
    Recommended name:
    Gap junction alpha-1 protein
    Protein Accession:
    P17302
    Secondary Accessions:
    • B2R5U9
    • Q6FHU1
    • Q9Y5I8

    Protein attributes for GJA1 Gene

    Size:
    382 amino acids
    Molecular mass:
    43008 Da
    Quaternary structure:
    • A connexon is composed of a hexamer of connexins. Interacts (via C-terminus) with TJP1 (By similarity). Interacts (via C-terminus) with SRC (via SH3 domain) (By similarity). Interacts (not ubiquitinated) with UBQLN4 (via UBA domain) (By similarity). Interacts with SGSM3 and CNST (By similarity). Interacts with RIC1/CIP150. Interacts with CSNK1D. Interacts with NOV (PubMed:15181016, PubMed:15213231). Interacts with TMEM65 (By similarity).

    Three dimensional structures from OCA and Proteopedia for GJA1 Gene

neXtProt entry for GJA1 Gene

Proteomics data for GJA1 Gene at MOPED

Post-translational modifications for GJA1 Gene

  • Phosphorylated at Ser-368 by PRKCG; phosphorylation induces disassembly of gap junction plaques and inhibition of gap junction activity (By similarity). Phosphorylation at Ser-325, Ser-328 and Ser-330 by CK1 modulates gap junction assembly. Phosphorylation at Ser-368 by PRKCD triggers its internalization into small vesicles leading to proteasome-mediated degradation (By similarity).
  • S-nitrosylation at Cys-271 is enriched at the muscle endothelial gap junction in arteries, it augments channel permeability and may regulate of smooth muscle cell to endothelial cell communication.
  • Sumoylated with SUMO1, SUMO2 and SUMO3, which may regulate the level of functional Cx43 gap junctions at the plasma membrane. May be desumoylated by SENP1 or SENP2.
  • Ubiquitination at Lys 9 and Lys 303
  • Modification sites at PhosphoSitePlus

Other Protein References for GJA1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GJA1 Gene

Domains & Families for GJA1 Gene

Gene Families for GJA1 Gene

Suggested Antigen Peptide Sequences for GJA1 Gene

Graphical View of Domain Structure for InterPro Entry

P17302

UniProtKB/Swiss-Prot:

CXA1_HUMAN :
  • Belongs to the connexin family. Alpha-type (group II) subfamily.
Family:
  • Belongs to the connexin family. Alpha-type (group II) subfamily.
genes like me logo Genes that share domains with GJA1: view

Function for GJA1 Gene

Molecular function for GJA1 Gene

GENATLAS Biochemistry:
gap junction protein,alpha 1,43kDa,connexin 43),expressed in the heart left ventricule,liver,peripheral nervous system,monomer of the connexon (six subunits),underexpressed in breast cancer cell (marker for detecting early oncogenesis in the breast)
UniProtKB/Swiss-Prot Function:
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract (By similarity). May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles (By similarity).
genes like me logo Genes that share phenotypes with GJA1: view

Human Phenotype Ontology for GJA1 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for GJA1 Gene

MGI Knock Outs for GJA1:

Animal Model Products

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for GJA1

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Transcription Factor Targets and HOMER Transcription for GJA1 Gene

Localization for GJA1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GJA1 Gene

Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Endoplasmic reticulum. Note=Localizes at the intercalated disk (ICD) in cardiomyocytes and the proper localization at ICD is dependent on TMEM65. {ECO:0000250 UniProtKB:P23242}.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for GJA1 Gene COMPARTMENTS Subcellular localization image for GJA1 gene
Compartment Confidence
endoplasmic reticulum 5
extracellular 5
golgi apparatus 5
mitochondrion 5
plasma membrane 5
cytoskeleton 4
cytosol 3
endosome 3
lysosome 3
vacuole 3
nucleus 2

Gene Ontology (GO) - Cellular Components for GJA1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion IDA 15919068
GO:0005768 endosome IEA --
GO:0005770 late endosome IEA --
GO:0005789 endoplasmic reticulum membrane TAS --
GO:0005916 fascia adherens IEA --
genes like me logo Genes that share ontologies with GJA1: view

Pathways & Interactions for GJA1 Gene

genes like me logo Genes that share pathways with GJA1: view

SIGNOR curated interactions for GJA1 Gene

Is activated by:
Is inactivated by:

Gene Ontology (GO) - Biological Process for GJA1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001649 osteoblast differentiation IEA --
GO:0001701 in utero embryonic development IEA --
GO:0001764 neuron migration IEA --
GO:0001937 negative regulation of endothelial cell proliferation IEA --
GO:0001947 heart looping IEA --
genes like me logo Genes that share ontologies with GJA1: view

Drugs & Compounds for GJA1 Gene

(73) Drugs for GJA1 Gene - From: Novoseek, IUPHAR, DGIdb, Tocris, and DrugBank

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Carvedilol Approved, Investigational Pharma Antagonist, Target, other 153
Carbenoxolone Experimental Pharma Inhibitor 0
Flufenamic acid Experimental Pharma Channel blocker Activates TRPC6; NSAID 0
Ca<sup>2+</sup> Pharma Activator 0
octanol Pharma Inhibitor 0

(53) Additional Compounds for GJA1 Gene - From: Novoseek and HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
8-Hydroxycarvedilol
genes like me logo Genes that share compounds with GJA1: view

Transcripts for GJA1 Gene

mRNA/cDNA for GJA1 Gene

(1) REFSEQ mRNAs :
(14) Additional mRNA sequences :
(391) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for GJA1 Gene

Gap junction protein, alpha 1, 43kDa:
Representative Sequences:

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for GJA1

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for GJA1 Gene

No ASD Table

Relevant External Links for GJA1 Gene

GeneLoc Exon Structure for
GJA1
ECgene alternative splicing isoforms for
GJA1

Expression for GJA1 Gene

mRNA expression in normal human tissues for GJA1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for GJA1 Gene

This gene is overexpressed in Frontal cortex (24.6), Spinal cord (19.8), and Testis (10.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for GJA1 Gene



SOURCE GeneReport for Unigene cluster for GJA1 Gene Hs.74471

mRNA Expression by UniProt/SwissProt for GJA1 Gene

P17302-CXA1_HUMAN
Tissue specificity: Expressed in the heart and fetal cochlea.
genes like me logo Genes that share expression patterns with GJA1: view

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues and Protein tissue co-expression partners for GJA1 Gene

Orthologs for GJA1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for GJA1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia GJA1 35
  • 99.48 (n)
  • 99.74 (a)
GJA1 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia GJA1 36
  • 97 (a)
OneToOne
GJA1 35
  • 92.32 (n)
  • 97.64 (a)
dog
(Canis familiaris)
Mammalia GJA1 35
  • 92.41 (n)
  • 98.17 (a)
GJA1 36
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gja1 16
Gja6 36
  • 63 (a)
OneToOne
Gja1 35
  • 88.22 (n)
  • 97.38 (a)
oppossum
(Monodelphis domestica)
Mammalia GJA1 36
  • 98 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia GJA1 36
  • 96 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Gja1 35
  • 87.96 (n)
  • 97.64 (a)
chicken
(Gallus gallus)
Aves GJA1 36
  • 94 (a)
OneToOne
GJA1 35
  • 82.15 (n)
  • 93.7 (a)
lizard
(Anolis carolinensis)
Reptilia GJA1 36
  • 86 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia gja1-A 35
tropical clawed frog
(Silurana tropicalis)
Amphibia gja1 35
  • 77.92 (n)
  • 87.07 (a)
zebrafish
(Danio rerio)
Actinopterygii cx40.8 36
  • 69 (a)
OneToOne
cx43 35
  • 72.89 (n)
  • 81.05 (a)
Species with no ortholog for GJA1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GJA1 Gene

ENSEMBL:
Gene Tree for GJA1 (if available)
TreeFam:
Gene Tree for GJA1 (if available)

Paralogs for GJA1 Gene

Paralogs for GJA1 Gene

(16) SIMAP similar genes for GJA1 Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for GJA1 Gene

genes like me logo Genes that share paralogs with GJA1: view

Variants for GJA1 Gene

Sequence variations from dbSNP and Humsavar for GJA1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
VAR_015760 Oculodentodigital dysplasia (ODDD)
VAR_015761 Oculodentodigital dysplasia (ODDD)
VAR_015762 Oculodentodigital dysplasia (ODDD)
VAR_015763 Oculodentodigital dysplasia (ODDD)
rs17653265 - 121,447,605(+) TGGTG(C/T)GCTGA reference, missense

Variation tolerance for GJA1 Gene

Residual Variation Intolerance Score: 16.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.95; 19.71% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for GJA1 Gene

HapMap Linkage Disequilibrium report
GJA1
Human Gene Mutation Database (HGMD)
GJA1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for GJA1 Gene

Disorders for GJA1 Gene

MalaCards: The human disease database

(37) MalaCards diseases for GJA1 Gene - From: OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
oculodentodigital dysplasia
  • odd syndrome
syndactyly, type iii
  • syndactyly type 3
atrioventricular septal defect 3
  • avsd3
craniometaphyseal dysplasia, autosomal recessive
  • craniometaphyseal dysplasia, autosomal recessive type
hypoplastic left heart syndrome 1
  • hypoplastic left heart syndrome
- elite association - COSMIC cancer census association via MalaCards
Search GJA1 in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

CXA1_HUMAN
  • Oculodentodigital dysplasia (ODDD) [MIM:164200]: A disease characterized by a typical facial appearance and variable involvement of the eyes, dentition, and fingers. Characteristic facial features include a narrow, pinched nose with hypoplastic alae nasi, prominent columella and thin anteverted nares together with a narrow nasal bridge, and prominent epicanthic folds giving the impression of hypertelorism. The teeth are usually small and carious. Typical eye findings include microphthalmia and microcornea. The characteristic digital malformation is complete syndactyly of the fourth and fifth fingers (syndactyly type III) but the third finger may be involved and associated camptodactyly is a common finding. Cardiac abnormalities are observed in rare instances. {ECO:0000269 PubMed:12457340, ECO:0000269 PubMed:14729836, ECO:0000269 PubMed:15108203, ECO:0000269 PubMed:15637728, ECO:0000269 PubMed:16219735, ECO:0000269 PubMed:16222672, ECO:0000269 PubMed:16378922, ECO:0000269 PubMed:16709485, ECO:0000269 PubMed:16813608, ECO:0000269 PubMed:16816024, ECO:0000269 PubMed:17509830, ECO:0000269 PubMed:18161618, ECO:0000269 PubMed:19338053, ECO:0000269 PubMed:21670345, ECO:0000269 PubMed:23550541, ECO:0000269 PubMed:24508941}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Oculodentodigital dysplasia, autosomal recessive (ODDD-AR) [MIM:257850]: A disease characterized by a typical facial appearance and variable involvement of the eyes, dentition, and fingers. Characteristic facial features include a narrow, pinched nose with hypoplastic alae nasi, prominent columella and thin anteverted nares together with a narrow nasal bridge, and prominent epicanthic folds giving the impression of hypertelorism. The teeth are usually small and carious. Typical eye findings include microphthalmia and microcornea. The characteristic digital malformation is complete syndactyly of the fourth and fifth fingers (syndactyly type III) but the third finger may be involved and associated camptodactyly is a common finding. Cardiac abnormalities are observed in rare instances. {ECO:0000269 PubMed:16816024}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Syndactyly 3 (SDTY3) [MIM:186100]: A form of syndactyly, a congenital anomaly of the hand or foot marked by persistence of the webbing between adjacent digits that are more or less completely attached. In SDTY3, there is usually complete and bilateral syndactyly between the fourth and fifth fingers. Usually it is soft tissue syndactyly but occasionally the distal phalanges are fused. The fifth finger is short with absent or rudimentary middle phalanx. The feet are not affected. {ECO:0000269 PubMed:14729836}. Note=The disease may be caused by mutations affecting the gene represented in this entry.
  • Hypoplastic left heart syndrome 1 (HLHS1) [MIM:241550]: A syndrome due to defective development of the aorta proximal to the entrance of the ductus arteriosus, and hypoplasia of the left ventricle and mitral valve. As a result of the abnormal circulation, the ductus arteriosus and foramen ovale are patent and the right atrium, right ventricle, and pulmonary artery are enlarged. {ECO:0000269 PubMed:11470490}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Hallermann-Streiff syndrome (HSS) [MIM:234100]: A disorder characterized by a typical skull shape (brachycephaly with frontal bossing), hypotrichosis, microphthalmia, cataracts, beaked nose, micrognathia, skin atrophy, dental anomalies and proportionate short stature. Mental retardation is present in a minority of cases. {ECO:0000269 PubMed:14974090}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Atrioventricular septal defect 3 (AVSD3) [MIM:600309]: A congenital heart malformation characterized by a common atrioventricular junction coexisting with deficient atrioventricular septation. The complete form involves underdevelopment of the lower part of the atrial septum and the upper part of the ventricular septum; the valve itself is also shared. A less severe form, known as ostium primum atrial septal defect, is characterized by separate atrioventricular valvar orifices despite a common junction. {ECO:0000269 PubMed:11470490}. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • Craniometaphyseal dysplasia, autosomal recessive (CMDR) [MIM:218400]: An osteochondrodysplasia characterized by hyperostosis and sclerosis of the craniofacial bones associated with abnormal modeling of the metaphyses. Sclerosis of the skull may lead to asymmetry of the mandible, as well as to cranial nerve compression, that may finally result in hearing loss and facial palsy. {ECO:0000269 PubMed:23951358}. Note=The disease is caused by mutations affecting the gene represented in this entry.

Relevant External Links for GJA1

Genetic Association Database (GAD)
GJA1
Human Genome Epidemiology (HuGE) Navigator
GJA1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
GJA1
genes like me logo Genes that share disorders with GJA1: view

No data available for Genatlas for GJA1 Gene

Publications for GJA1 Gene

  1. The human connexin gene family of gap junction proteins: distinct chromosomal locations but similar structures. (PMID: 1646158) Fishman G.I. … Leinwand L.A. (Genomics 1991) 2 3 4 67
  2. Rac1-induced connective tissue growth factor regulates connexin 43 and N-cadherin expression in atrial fibrillation. (PMID: 20117462) Adam O. … Laufs U. (J. Am. Coll. Cardiol. 2010) 3 23
  3. Enhanced connexin 43 expression delays intra-mitotic duration and cell cycle traverse independently of gap junction channel function. (PMID: 20512937) Johnstone S.R. … Martin P.E. (J. Cell. Biochem. 2010) 3 23
  4. Oculo-dento-digital dysplasia: lack of genotype-phenotype correlation for GJA1 mutations and usefulness of neuro-imaging. (PMID: 19808103) Alao M.J. … Lacombe D. (Eur J Med Genet 2010) 3 23
  5. The tumor-suppressive function of Connexin43 in keratinocytes is mediated in part via interaction with caveolin-1. (PMID: 20406988) Langlois S. … Laird D.W. (Cancer Res. 2010) 3 23

Products for GJA1 Gene

Sources for GJA1 Gene

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