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Aliases for GINM1 Gene

Aliases for GINM1 Gene

  • Glycoprotein Integral Membrane 1 2 3 5
  • C6orf72 3 4
  • Chromosome 6 Open Reading Frame 72 2
  • DJ12G14.2 3

External Ids for GINM1 Gene

Previous HGNC Symbols for GINM1 Gene

  • C6orf72

Previous GeneCards Identifiers for GINM1 Gene

  • GC06P149888

Summaries for GINM1 Gene

GeneCards Summary for GINM1 Gene

GINM1 (Glycoprotein Integral Membrane 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GINM1 Gene

Genomics for GINM1 Gene

Regulatory Elements for GINM1 Gene

Enhancers for GINM1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around GINM1 on UCSC Golden Path with GeneCards custom track

Promoters for GINM1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around GINM1 on UCSC Golden Path with GeneCards custom track

Genomic Location for GINM1 Gene

Chromosome:
6
Start:
149,566,294 bp from pter
End:
149,591,748 bp from pter
Size:
25,455 bases
Orientation:
Plus strand

Genomic View for GINM1 Gene

Genes around GINM1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
GINM1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for GINM1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GINM1 Gene

Proteins for GINM1 Gene

  • Protein details for GINM1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NU53-GINM1_HUMAN
    Recommended name:
    Glycoprotein integral membrane protein 1
    Protein Accession:
    Q9NU53
    Secondary Accessions:
    • B2RDY7
    • E1P5A2

    Protein attributes for GINM1 Gene

    Size:
    330 amino acids
    Molecular mass:
    36840 Da
    Quaternary structure:
    No Data Available

neXtProt entry for GINM1 Gene

Proteomics data for GINM1 Gene at MOPED

Post-translational modifications for GINM1 Gene

  • Ubiquitination at Lys 294, Lys 301, Lys 319, and Lys 327
  • Modification sites at PhosphoSitePlus

Other Protein References for GINM1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for GINM1 Gene

Domains & Families for GINM1 Gene

Protein Domains for GINM1 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for GINM1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with GINM1: view

No data available for Gene Families and UniProtKB/Swiss-Prot for GINM1 Gene

Function for GINM1 Gene

genes like me logo Genes that share phenotypes with GINM1: view

Animal Model Products

miRNA for GINM1 Gene

miRTarBase miRNAs that target GINM1

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for GINM1 Gene

Localization for GINM1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for GINM1 Gene

Membrane; Single-pass type I membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for GINM1 Gene COMPARTMENTS Subcellular localization image for GINM1 gene
Compartment Confidence
extracellular 5
plasma membrane 4
nucleus 3
endoplasmic reticulum 1

Gene Ontology (GO) - Cellular Components for GINM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0070062 extracellular exosome IDA 23376485
genes like me logo Genes that share ontologies with GINM1: view

Pathways & Interactions for GINM1 Gene

SuperPathways for GINM1 Gene

No Data Available

Interacting Proteins for GINM1 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000356389%0d%0a9606.ENSP00000344818%0d%0a
Selected Interacting proteins: ENSP00000356389 for GINM1 Gene via STRING

Symbol External ID(s) Details
UBC

Gene Ontology (GO) - Biological Process for GINM1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for GINM1 Gene

Drugs & Compounds for GINM1 Gene

No Compound Related Data Available

Transcripts for GINM1 Gene

mRNA/cDNA for GINM1 Gene

Unigene Clusters for GINM1 Gene

Glycoprotein integral membrane 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for GINM1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8
SP1: -
SP2: -

Relevant External Links for GINM1 Gene

GeneLoc Exon Structure for
GINM1
ECgene alternative splicing isoforms for
GINM1

Expression for GINM1 Gene

mRNA expression in normal human tissues for GINM1 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for GINM1 Gene



SOURCE GeneReport for Unigene cluster for GINM1 Gene Hs.438872

genes like me logo Genes that share expression patterns with GINM1: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for GINM1 Gene

Orthologs for GINM1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for GINM1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia GINM1 35
  • 88.82 (n)
  • 87.2 (a)
MGC133692 36
  • 87 (a)
OneToOne
dog
(Canis familiaris)
Mammalia GINM1 35
  • 88.07 (n)
  • 85.28 (a)
GINM1 36
  • 80 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Ginm1 35
  • 80.94 (n)
  • 74.62 (a)
Ginm1 16
Ginm1 36
  • 74 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia GINM1 36
  • 64 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia GINM1 36
  • 54 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia GINM1 36
  • 99 (a)
OneToOne
GINM1 35
  • 99.29 (n)
  • 99.39 (a)
rat
(Rattus norvegicus)
Mammalia Ginm1 35
  • 81.81 (n)
  • 75 (a)
chicken
(Gallus gallus)
Aves C3H6ORF72 35
  • 68.05 (n)
  • 60.51 (a)
C3H6ORF72 36
  • 59 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 56 (a)
OneToMany
-- 36
  • 57 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii si:dkey-15j16.2 35
  • 49.75 (n)
  • 35.34 (a)
ginm1 36
  • 28 (a)
OneToOne
Species with no ortholog for GINM1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GINM1 Gene

ENSEMBL:
Gene Tree for GINM1 (if available)
TreeFam:
Gene Tree for GINM1 (if available)

Paralogs for GINM1 Gene

No data available for Paralogs for GINM1 Gene

Variants for GINM1 Gene

Sequence variations from dbSNP and Humsavar for GINM1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1065333 -- 149,591,408(+) CAAAA(A/G)AAAAA downstream-variant-500B
rs1137086 -- 149,582,461(+) TGGAA(A/G)AGTTT reference, missense
rs1137089 -- 149,591,088(+) AGATC(A/G)AGACC downstream-variant-500B
rs9498372 -- 149,567,128(+) CTGGG(A/G)ACTCA intron-variant
rs9498373 -- 149,568,851(+) gagac(A/G)gaata intron-variant

Variation tolerance for GINM1 Gene

Residual Variation Intolerance Score: 58.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.99; 49.79% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for GINM1 Gene

HapMap Linkage Disequilibrium report
GINM1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for GINM1 Gene

Disorders for GINM1 Gene

Relevant External Links for GINM1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
GINM1

No disorders were found for GINM1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for GINM1 Gene

Publications for GINM1 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Proteomic analysis of podocyte exosome-enriched fraction from normal human urine. (PMID: 23376485) Prunotto M. … Moll S. (J Proteomics 2013) 3
  4. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3
  5. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 3

Products for GINM1 Gene

Sources for GINM1 Gene

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