Aliases for GIMAP5 Gene
External Ids for GIMAP5 Gene
Previous HGNC Symbols for GIMAP5 Gene
Previous GeneCards Identifiers for GIMAP5 Gene
This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene encodes an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between this gene and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene. [provided by RefSeq, Dec 2010]
GeneCards Summary for GIMAP5 Gene
GIMAP5 (GTPase, IMAP Family Member 5) is a Protein Coding gene. Among its related pathways are NF-kappaB Signaling and Apoptosis and Autophagy. GO annotations related to this gene include GTP binding. An important paralog of this gene is GIMAP4.
UniProtKB/Swiss-Prot for GIMAP5 Gene
Required for mitochondrial integrity and T-cell survival. May contribute to T-cell quiescence (By similarity).