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GIGYF1 Gene

protein-coding   GIFtS: 51
GCID: GC07M100277

GRB10 Interacting GYF Protein 1

(Previous names: PERQ amino acid rich, with GYF domain 1)
(Previous symbol: PERQ1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
GRB10 Interacting GYF Protein 11 2     GYF12
PERQ11 2 3     PERQ Amino Acid-Rich With GYF Domain-Containing Protein 12
PERQ Amino Acid Rich, With GYF Domain 11 2     Postmeiotic Segregation Increased 2-Like 122
GYF Domain Containing 11 2     CDS23
GRB10-Interacting GYF Protein 12 3     

External Ids:    HGNC: 91261   Entrez Gene: 645992   Ensembl: ENSG000001468307   OMIM: 6120645   UniProtKB: O754203   

Export aliases for GIGYF1 gene to outside databases

Previous GC identifers: GC07M100116 GC07M094907


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for GIGYF1 Gene:
GIGYF1 (GRB10 interacting GYF protein 1) is a protein-coding gene. Diseases associated with GIGYF1 include ataxia, and breast cancer. An important paralog of this gene is GIGYF2.

UniProtKB/Swiss-Prot: PERQ1_HUMAN, O75420
Function: May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling. May increase IGF1
receptor phosphorylation under IGF1 stimulation as well as phosphorylation of IRS1 and SHC1 (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000007.14  NT_007933.16  NC_018918.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the GIGYF1 gene promoter:
         ER-alpha   ISGF-3   AP-1   Brachyury   ATF-2   CREB   POU2F1   POU2F1a   deltaCREB   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): GIGYF1 promoter sequence
   Search Chromatin IP Primers for GIGYF1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat GIGYF1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q22   Ensembl cytogenetic band:  7q22.1   HGNC cytogenetic band: 7q22

GIGYF1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GIGYF1 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M100277:  view genomic region     (about GC identifiers)

Start:
100,277,130 bp from pter      End:
100,287,071 bp from pter
Size:
9,942 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 99,636,735-99,646,475     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: PERQ1_HUMAN, O75420 (See protein sequence)
Recommended Name: PERQ amino acid-rich with GYF domain-containing protein 1  
Size: 1035 amino acids; 114601 Da
Subunit: Interacts with GRB10. This transient binding is increased under IGF1 stimulation and leads to recruitment
of GIGYF1/GRB10 complex to IGF1 receptor (By similarity)
Sequence caution: Sequence=AAC78792.1; Type=Erroneous gene model prediction; Sequence=AAL55738.1; Type=Frameshift;
Positions=784, 856;
Secondary accessions: Q6Y7W7 Q8WZ38

Explore the universe of human proteins at neXtProt for GIGYF1: NX_O75420

Explore proteomics data for GIGYF1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See GIGYF1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_072096.2  
    ENSEMBL proteins: 
     ENSP00000275732  

    GIGYF1 Human Recombinant Protein Products:

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR003169 GYF

    Graphical View of Domain Structure for InterPro Entry O75420

    ProtoNet protein and cluster: O75420

    1 Blocks protein domain: IPB003169 CD2-binding protein

    UniProtKB/Swiss-Prot: PERQ1_HUMAN, O75420
    Domain: The GYF domain interacts with GRB10 (By similarity)
    Similarity: Belongs to the PERQ family
    Similarity: Contains 1 GYF domain


    GIGYF1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: PERQ1_HUMAN, O75420
    Function: May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling. May increase IGF1
    receptor phosphorylation under IGF1 stimulation as well as phosphorylation of IRS1 and SHC1 (By similarity)

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
         
    GIGYF1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for GIGYF1:
     Decreased homologous recombina  Proliferating cells 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for GIGYF1
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for GIGYF1
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    miRNA
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    miRTarBase miRNAs that target GIGYF1:
    hsa-mir-324-5p (MIRT043251), hsa-mir-615-3p (MIRT039789), hsa-mir-877-3p (MIRT036865), hsa-mir-181a-5p (MIRT025203), hsa-mir-204-5p (MIRT047013), hsa-mir-149-5p (MIRT045609), hsa-mir-18a-5p (MIRT031358), hsa-mir-193b-3p (MIRT041515), hsa-mir-484 (MIRT042243), hsa-mir-18b-5p (MIRT042411)

    Block miRNA regulation of human, mouse, rat GIGYF1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate GIGYF1 (see all 118):
    hsa-miR-3607-3p hsa-miR-520e hsa-miR-15a hsa-miR-106a hsa-miR-200a hsa-miR-30d hsa-miR-30a hsa-miR-637
    SwitchGear 3'UTR luciferase reporter plasmidGIGYF1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat GIGYF1

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GIGYF1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytoskeleton2
    cytosol2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for GIGYF1
    Interactions:

        Search GeneGlobe Interaction Network for GIGYF1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for GIGYF1 (O754202, 3 ENSP000002757324) via UniProtKB, MINT, STRING, and/or I2D (see all 52)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ATN1P542592, 3, ENSP000003490764MINT-2875806 I2D: score=3 STRING: ENSP00000349076
    ESR2Q927313, ENSP000003439254I2D: score=1 STRING: ENSP00000343925
    IGF1P050193, ENSP000003026654I2D: score=1 STRING: ENSP00000302665
    GRB10Q133223, ENSP000003817934I2D: score=4 STRING: ENSP00000381793
    CCBL2Q6YP213I2D: score=5 
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0048009insulin-like growth factor receptor signaling pathway IEA--

    GIGYF1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for GIGYF1 (PERQ1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for GIGYF1 gene: 
    NM_022574.4  

    Unigene Cluster for GIGYF1:

    GRB10 interacting GYF protein 1
    Hs.414396  [show with all ESTs]
    Unigene Representative Sequence: NM_022574
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000275732(uc003uwg.1) ENST00000472105 ENST00000471340 ENST00000464111

    miRNA
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    Block miRNA regulation of human, mouse, rat GIGYF1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate GIGYF1 (see all 118):
    hsa-miR-3607-3p hsa-miR-520e hsa-miR-15a hsa-miR-106a hsa-miR-200a hsa-miR-30d hsa-miR-30a hsa-miR-637
    SwitchGear 3'UTR luciferase reporter plasmidGIGYF1 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for GIGYF1
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    GenScript: all cDNA clones in your preferred vector: GIGYF1 (NM_022574)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GIGYF1
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    OriGene qSTAR qPCR primer pairs in human, mouse for GIGYF1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat GIGYF1
      QuantiTect SYBR Green Assays in human, mouse, rat GIGYF1
      QuantiFast Probe-based Assays in human, mouse, rat GIGYF1

    Additional mRNA sequence: 

    AF086157.1 AF088067.1 AF289554.1 AY176044.1 BC018563.1 BC036595.2 BC129991.1 

    7 DOTS entries:

    DT.111293  DT.97798907  DT.100025480  DT.100813994  DT.100813995  DT.95226684  DT.95363738 

    Selected AceView cDNA sequences (see all 115):

    BU782755 AI027669 AI659228 BM789051 W81502 AA782185 AI553986 AY176044 
    AF088067 AW207128 NM_022574 BQ071375 AA928244 AA425733 BQ013359 BU608012 
    BF939359 BU626335 CB242810 CF135747 AI871969 AI962391 AA813073 AI810290 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for GIGYF1 (see all 8)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b ^ 16a · 16b ^ 17 ^ 18a · 18b ^ 19 ^ 20 ^ 21
    SP1:                                                                                                                                                            
    SP2:                                                                                                                                                            
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            


    ECgene alternative splicing isoforms for GIGYF1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    GIGYF1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGCCTGGAGA
    GIGYF1 Expression
    About this image


    GIGYF1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Heart (Cardiovascular System)    fully expand to see all 2 entries
             Atrioventricular Canal Cells Atrioventricular Canal
             Outflow Tract
    GIGYF1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    GIGYF1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.414396
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GIGYF1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for GIGYF1 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Gigyf11 , 5 GRB10 interacting GYF protein 11, 5 86.93(n)1
    90.44(a)1
      5 (76.53 cM)5
    573301  NM_031408.21  NP_113596.21 
     1375188805 
    lizard
    (Anolis carolinensis)
    Reptilia GIGYF16
    GRB10 interacting GYF protein 1
    52(a)
    1 ↔ 1
    GL343926.1(88200-115086)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia gigyf11 GRB10 interacting GYF protein 1 64.58(n)
    63.52(a)
      780058  NM_001079135.1  NP_001072603.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5685841 PERQ amino acid-rich with GYF domain-containing protein more 65.15(n)
    63.49(a)
      568584  XM_001919904.4  XP_001919939.4 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG111486
    --
    14(a)
    1 → many
    4(876026-887652)


    ENSEMBL Gene Tree for GIGYF1 (if available)
    TreeFam Gene Tree for GIGYF1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for GIGYF1 gene
    GIGYF22  
    2 SIMAP similar genes for GIGYF1 using alignment to 2 protein entries:     PERQ1_HUMAN (see all proteins):
    PERQ1    GIGYF2

    GIGYF1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for GIGYF1 (see all 512)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1888584881,2
    --100277555(+) GGTGGA/GGGGGT 1 -- ut310--------
    rs751083961,2
    --100277863(+) GGAAAA/GAAACG 1 -- ut310--------
    rs561489281,2
    C,F--100277868(+) GAAACG/AGGCCA 1 -- ut311Minor allele frequency- A:0.06NA 120
    rs1425744291,2
    C--100277932(+) GGCGAA/GGCCTT 1 -- ut310--------
    rs1453240961,2
    C--100277995(+) AACCC-/AAAAGAC 1 -- ut310--------
    rs1819476881,2
    --100278026(+) AAATGA/GGCGGA 1 -- ut310--------
    rs1870433611,2
    --100278090(+) CAGCCG/TCCTCT 1 -- ut310--------
    rs1894914571,2
    --100278140(+) CCAACA/GGTAAA 1 -- ut310--------
    rs1166996781,2
    C,F--100278142(+) AACGGT/GAAAAA 1 -- ut311Minor allele frequency- G:0.03WA 118
    rs592680531,2
    C--100278165(+) AGACCC/TGGAAG 1 -- ut312Minor allele frequency- T:0.05WA 120

    HapMap Linkage Disequilibrium report for GIGYF1 (100277130 - 100287071 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for GIGYF1 (see all 11):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2734888CNV Deletion23290073
    nsv888792CNV Loss21882294
    nsv470381CNV Loss18288195
    nsv888791CNV Loss21882294
    nsv888779CNV Loss21882294
    nsv819414CNV Loss19587683
    dgv7401n71CNV Loss21882294
    dgv7399n71CNV Loss21882294
    nsv888795CNV Loss21882294
    nsv831072CNV Loss17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing GIGYF1
    DNA2.0 Custom Variant and Variant Library Synthesis for GIGYF1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612064    OMIM disorders: --

    2 diseases for GIGYF1:    
    About MalaCards
    ataxia    breast cancer


    GIGYF1 for disorders           About GeneDecksing


    Export disorders for GIGYF1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for GIGYF1 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with GIGYF1)
        Utopia: connect your pdf to the dynamic
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    1. Two novel proteins that are linked to insulin-like growth factor (IGF-I) receptors by the Grb10 adapter and modulate IGF-I signaling. (PubMed id 12771153)1, 2, 3 Giovannone B....Smith R.J. (J. Biol. Chem. 2003)
    2. Large-scale sequencing of two regions in human chromosome 7q22: analysis of 650 kb of genomic sequence around the EPO and CUTL1 loci reveals 17 genes. (PubMed id 9799793)1, 2, 3 Gloeckner G.... Rosenthal A. (Genome Res. 1998)
    3. Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PubMed id 24255178)1 Couzens A.L....Gingras A.C. (Sci Signal 2013)
    4. 14-3-3 proteins sequester a pool of soluble TRIM32 ubiquitin ligase to repress autoubiquitylation and cytoplasmic body formation. (PubMed id 23444366)1 Ichimura T....Hachiya N. (J. Cell. Sci. 2013)
    5. A novel 4EHP-GIGYF2 translational repressor complex is essential for mammalian development. (PubMed id 22751931)1 Morita M....Sonenberg N. (Mol. Cell. Biol. 2012)
    6. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    7. Critical involvement of RQCD1 in the EGFR-Akt pathway in mammary carcinogenesis. (PubMed id 20878056)1 Ajiro M....Nakamura Y. (Int. J. Oncol. 2010)
    8. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)
    9. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)
    10. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 64599 HGNC: 9126 AceView: PERQ1 Ensembl:ENSG00000146830 euGenes: HUgn64599
    ECgene: GIGYF1 H-InvDB: GIGYF1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for GIGYF1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for GIGYF1 gene:
    Search GeneIP for patents involving GIGYF1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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