Aliases for GIGYF1 Gene
External Ids for GIGYF1 Gene
Previous HGNC Symbols for GIGYF1 Gene
Previous GeneCards Identifiers for GIGYF1 Gene
This gene encodes a member of the gyf family of adaptor proteins. The encoded protein contains a gyf protein interaction domain. It binds growth factor receptor bound 10, another adaptor protein that binds activated insulin-like growth factor 1 and insulin receptors and regulates receptor signaling. [provided by RefSeq, Apr 2017]
GeneCards Summary for GIGYF1 Gene
GIGYF1 (GRB10 Interacting GYF Protein 1) is a Protein Coding gene. An important paralog of this gene is GIGYF2.
UniProtKB/Swiss-Prot for GIGYF1 Gene
May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling. May increase IGF1 receptor phosphorylation under IGF1 stimulation as well as phosphorylation of IRS1 and SHC1 (By similarity).