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Aliases for GID4 Gene

Aliases for GID4 Gene

  • GID Complex Subunit 4 2 3
  • Vacuolar Import And Degradation Protein 24 Homolog 3 4
  • Vacuolar Import And Degradation 24 2 3
  • C17orf39 3 4
  • VID24 3 4
  • GID Complex Subunit 4, VID24 Homolog (S. Cerevisiae) 2
  • Glucose-Induced Degradation Protein 4 Homolog 3
  • GID Complex Subunit 4, VID24 Homolog 3
  • Chromosome 17 Open Reading Frame 39 2

External Ids for GID4 Gene

Previous Symbols for GID4 Gene

  • C17orf39

Summaries for GID4 Gene

Entrez Gene Summary for GID4 Gene

  • The multiprotein Mediator complex is a coactivator required for activation of RNA polymerase II transcription by DNA bound transcription factors. The protein encoded by this gene is thought to be a subunit of the Mediator complex. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]

GeneCards Summary for GID4 Gene

GID4 (GID Complex Subunit 4) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for GID4 Gene

Genomics for GID4 Gene

Genomic Location for GID4 Gene

Start:
18,039,292 bp from pter
End:
18,068,405 bp from pter
Size:
29,114 bases
Orientation:
Plus strand

Genomic View for GID4 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for GID4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for GID4 Gene

No data available for Regulatory Elements for GID4 Gene

Proteins for GID4 Gene

  • Protein details for GID4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IVV7-GID4_HUMAN
    Recommended name:
    Glucose-induced degradation protein 4 homolog
    Protein Accession:
    Q8IVV7
    Secondary Accessions:
    • Q8TEB5
    • Q9BW50

    Protein attributes for GID4 Gene

    Size:
    300 amino acids
    Molecular mass:
    33514 Da
    Quaternary structure:
    No Data Available

neXtProt entry for GID4 Gene

Proteomics data for GID4 Gene at MOPED

Post-translational modifications for GID4 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for GID4 Gene

No data available for DME Specific Peptides for GID4 Gene

Domains for GID4 Gene

Protein Domains for GID4 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

GID4_HUMAN
Family:
  • Belongs to the GID4/VID24 family.:
    • Q8IVV7
genes like me logo Genes that share domains with GID4: view

No data available for Gene Families for GID4 Gene

Function for GID4 Gene

miRNA for GID4 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for GID4 Gene

Localization for GID4 Gene

No data available for Gene Ontology (GO) - Cellular Components for GID4 Gene

Pathways for GID4 Gene

SuperPathways for GID4 Gene

No Data Available

Interacting Proteins for GID4 Gene

Gene Ontology (GO) - Biological Process for GID4 Gene

None

No data available for Pathways by source for GID4 Gene

Transcripts for GID4 Gene

Unigene Clusters for GID4 Gene

GID complex subunit 4, VID24 homolog (S. cerevisiae):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for GID4 Gene

No ASD Table

Relevant External Links for GID4 Gene

GeneLoc Exon Structure for
GID4
ECgene alternative splicing isoforms for
GID4

Expression for GID4 Gene

mRNA expression in normal human tissues for GID4 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for GID4 Gene

SOURCE GeneReport for Unigene cluster for GID4 Gene Hs.187422

genes like me logo Genes that share expressions with GID4: view

Orthologs for GID4 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for GID4 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia GID4 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C19H17ORF39 37
  • 99 (a)
OneToOne
GID4 36
  • 90.94 (n)
  • 99.08 (a)
dog
(Canis familiaris)
Mammalia GID4 36
  • 94.59 (n)
  • 100 (a)
GID4 37
  • 86 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gid4 36
  • 93.55 (n)
  • 99.08 (a)
Gid4 16
Gid4 37
  • 99 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia GID4 37
  • 97 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia GID4 37
  • 97 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Gid4 36
  • 94.16 (n)
  • 99.54 (a)
chicken
(Gallus gallus)
Aves C17ORF39 36
  • 82.8 (n)
  • 89.4 (a)
GID4 37
  • 79 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia GID4 37
  • 80 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia gid4 36
  • 81.85 (n)
  • 91.55 (a)
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.5699 36
zebrafish
(Danio rerio)
Actinopterygii GID4 37
  • 88 (a)
OneToOne
LOC100333066 36
  • 79.11 (n)
  • 88.94 (a)
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP000312 36
  • 69.46 (n)
  • 77.34 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 37
  • 24 (a)
OneToMany
-- 39
VID24 37
  • 22 (a)
OneToMany
thale cress
(Arabidopsis thaliana)
eudicotyledons AT2G37680 36
  • 48.04 (n)
  • 39.41 (a)
rice
(Oryza sativa)
Liliopsida Os03g0679000 36
  • 47.94 (n)
  • 37.64 (a)
bread mold
(Neurospora crassa)
Ascomycetes NCU04406 36
  • 54.99 (n)
  • 51.98 (a)
sea squirt
(Ciona intestinalis)
Ascidiacea Cin.7644 36
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 66 (a)
OneToOne
Species with no ortholog for GID4:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for GID4 Gene

ENSEMBL:
Gene Tree for GID4 (if available)
TreeFam:
Gene Tree for GID4 (if available)

Paralogs for GID4 Gene

No data available for Paralogs for GID4 Gene

Variants for GID4 Gene

Sequence variations from dbSNP and Humsavar for GID4 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs1133710 -- 18,068,068(+) TTTGC(C/T)TTCAG utr-variant-3-prime
rs2955350 -- 18,050,234(+) TGGGT(A/G)TATAC intron-variant
rs2955352 -- 18,058,075(+) TGATC(C/T)GCCTG intron-variant
rs2955353 -- 18,045,665(-) TGCAC(A/G)CCTCA intron-variant
rs2955354 -- 18,045,402(-) TAAAA(C/G)ATTTG intron-variant

Relevant External Links for GID4 Gene

HapMap Linkage Disequilibrium report
GID4

No data available for Structural Variations from Database of Genomic Variants (DGV) for GID4 Gene

Disorders for GID4 Gene

No disorders were found for GID4 Gene.

No data available for UniProtKB/Swiss-Prot for GID4 Gene

Publications for GID4 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Genes in a refined Smith-Magenis syndrome critical deletion interval on chromosome 17p11.2 and the syntenic region of the mouse. (PMID: 11997338) Bi W. … Lupski J.R. (Genome Res. 2002) 2 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Genomic organisation of the approximately 1.5 Mb Smith-Magenis syndrome critical interval: transcription map, genomic contig, and candidate gene analysis. (PMID: 11840190) Lucas R.E. … Elsea S.H. (Eur. J. Hum. Genet. 2001) 3

Products for GID4 Gene

Sources for GID4 Gene

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