Aliases for GGT6 Gene
External Ids for GGT6 Gene
Previous GeneCards Identifiers for GGT6 Gene
GGT6 belongs to the gamma-glutamyltransferase (GGT; EC 18.104.22.168) gene family. GGT is a membrane-bound extracellular enzyme that cleaves gamma-glutamyl peptide bonds in glutathione and other peptides and transfers the gamma-glutamyl moiety to acceptors. GGT is also key to glutathione homeostasis because it provides substrates for glutathione synthesis (Heisterkamp et al., 2008 [PubMed 18357469]).[supplied by OMIM, Oct 2008]
GeneCards Summary for GGT6 Gene
GGT6 (Gamma-Glutamyltransferase 6) is a Protein Coding gene. Diseases associated with GGT6 include Glutathionuria. Among its related pathways are Aflatoxin activation and detoxification and Taurine and hypotaurine metabolism. GO annotations related to this gene include gamma-glutamyltransferase activity and glutathione hydrolase activity. An important paralog of this gene is GGT1.
UniProtKB/Swiss-Prot for GGT6 Gene
Cleaves glutathione conjugates.