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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

GGN Gene

protein-coding GIFtS: 45
GCID: GC19M038874

Gametogenetin

4 related diseases
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
gametogenetin¹ ²

External Ids:	HGNC: 18869¹	Entrez Gene: 199720²	Ensembl: ENSG00000179168⁷	OMIM: 609966⁵	UniProtKB: Q86UU5³

Export aliases for GGN gene to outside databases

Previous GC identifers: GC19M043551 GC19M043566 GC19M035322

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GGN Gene:

This gene is a germ cell-specific gene that encodes proteins that interact with POG (proliferation of germ cells).

Alternatively spliced transcript variants of a similar mouse gene encode at least three different proteins,

namely gametogenetin protein 1a, gametogenetin protein 2, and gametogenetin protein 3, which show a perinuclear,

cytoplasmic, and nucleolar localization, respectively. These proteins regulate the localization of POG and may

play a role in spermatogenesis. (provided by RefSeq, Jul 2008)

GeneCards Summary for GGN Gene:

GGN (gametogenetin) is a protein-coding gene. Diseases associated with GGN include hypospadias, and male infertility. GO annotations related to this gene include protein dimerization activity.

UniProtKB/Swiss-Prot: GGN_HUMAN, Q86UU5

Function: May be involved in spermatogenesis (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000019.9 NT_011109.16 NC_018930.2

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the GGN gene promoter:
E2F-4 E2F-3a E2F-5 Nkx2-5 E2F-2 CREB E2F-1 E2F deltaCREB Zic3
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: GGN promoter sequence

Search SABiosciences Chromatin IP Primers for GGN

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GGN

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.2 Ensembl cytogenetic band: 19q13.2 HGNC cytogenetic band: 19q13.2

GGN Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GGN gene location

GeneLoc information about chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19M038874: view genomic region (about GC identifiers)

Start:	38,874,905 bp from pter	End:	38,878,722 bp from pter
Size:	3,818 bases	Orientation:	minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: GGN_HUMAN, Q86UU5 (See protein sequence)

Recommended Name: Gametogenetin

Size: 652 amino acids; 66699 Da

Subunit: Interacts with FANCL, GGNBP1 and ZNF403/GGNBP2 (By similarity)

Secondary accessions: Q7RTU6 Q86UU4 Q8NAA1

Alternative splicing: 3 isoforms: Q86UU5-1 Q86UU5-2 Q86UU5-3

Explore the universe of human proteins at neXtProt for GGN: NX_Q86UU5

Explore proteomics data for GGN at MOPED

Post-translational modifications:

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_Q86UU5

GGN Protein expression data from MOPED¹, PaxDb² and MAXQB³ : About this image

REFSEQ proteins: NP_689870.3

ENSEMBL proteins:

ENSP00000334940 ENSP00000467295 ENSP00000467084 ENSP00000465186

Human Recombinant Protein Products for GGN:

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Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005730	nucleolus	IEA	--
GO:0005737	cytoplasm	--	--
GO:0048471	perinuclear region of cytoplasm	IEA	--

GGN for ontologies About GeneDecksing

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ProtoNet protein and cluster: Q86UU5

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: GGN_HUMAN, Q86UU5

Function: May be involved in spermatogenesis (By similarity)

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	--	--
GO:0046983	protein dimerization activity	IEA	--

GGN for ontologies About GeneDecksing

Phenotypes:
1 GenomeRNAi human phenotype for GGN:

Increased gamma-H2AX phosphory

3 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Ggn):

cellular

homeostasis/metabolism

mortality/aging

GGN for phenotypes About GeneDecksing

Animal Models:
MGI mouse knock-out Ggn^tm1Dpj for GGN

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In Situ Assay
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(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for GGN

STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

5 Interacting proteins for GGN (Q86UU5³ ENSP00000334940⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
GGNBP2	Q9H3C7³, ENSP00000307617⁴	I2D: score=3 STRING: ENSP00000307617
OAZ3	Q9UMX2³, ENSP00000313922⁴	I2D: score=2 STRING: ENSP00000313922
FANCL	Q9NW38³, ENSP00000385021⁴	I2D: score=1 STRING: ENSP00000385021
GGNBP1	Q5YKI7³, ENSP00000363582⁴	I2D: score=1 STRING: ENSP00000363582
CCNB1IP1	ENSP00000337396⁴	STRING: ENSP00000337396

About this table

Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0007275	multicellular organismal development	IEA	--
GO:0007276	gamete generation	ISS	--
GO:0007283	spermatogenesis	IEA	--
GO:0008104	protein localization	IEA	--
GO:0030154	cell differentiation	IEA	--

GGN for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

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Search CenterWatch for drugs/clinical trials and news about GGN

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for GGN gene (2 alternative transcripts):

NM_152657.3 NM_182477.1

Unigene Cluster for GGN:

Gametogenetin

Hs.447948 [show with all ESTs]

Unigene Representative Sequence: AF538035

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000334928(uc002oij.1 uc002oik.1 uc010efy.1) ENST00000591809

ENST00000585737 ENST00000586599 ENST00000587676

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Additional mRNA sequence:

AF538035.1 AF538037.1 AK057356.2 AK093032.1 BC035008.2

4 DOTS entries:

DT.100018246 DT.121433500 DT.121433499 DT.92059597

24/34 AceView cDNA sequences (see all 34):

AK093032 AI656796 NM_152657 BX098794 AA609137 AW949856 AX747869 BC035008

AI201296 AA383127 AF538037 AI016248 AA400144 AA609724 BQ064582 BK000550

AF538035 AA971327 AA725026 AK057356 AA421507 AF538036 NM_182477 AI024165

GeneLoc Exon Structure

5/6 Alternative Splicing Database (ASD) splice patterns (SP) for GGN (see all 6) About this scheme

ExUns:	1a	·	1b	^	2a	·	2b	^	3	^	4a	·	4b	·	4c	^	5	^	6	^	7
SP1:					-				-		-
SP2:					-										-
SP3:					-
SP4:					-				-		-		-		-		-
SP5:

ECgene alternative splicing isoforms for GGN

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

GGN expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: CCAATAAAAT

About this image

See GGN Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for GGN

SOURCE GeneReport for Unigene cluster: Hs.447948

SABiosciences Custom PCR Arrays for GGN

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In Situ
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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for GGN gene from 3/7 species (see all 7) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Ggn^{1 , 5}	gametogenetin^{1, 5}	79.13(n)¹ 75.27(a)¹		7 (16.94 cM)⁵ 243897¹ NM_182694.2¹ NP_874353.2¹ 29170220⁵
chicken (Gallus gallus)	Aves	GGN⁶	gametogenetin	19(a)	1 ↔ 1	AADN03024083.1(21-1598)
fruit fly (Drosophila melanogaster)	Insecta	CG14218⁶	--	22(a)	1 ↔ 1	X(19474376-19475715)

ENSEMBL Gene Tree for GGN (if available)
TreeFam Gene Tree for GGN (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 19 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs112267921^1,2	C,F	--	38874994(+)	`GCATCT/GGGATT`	1	--	ut3¹		1		EU	1295
rs62123481^1,2	C,F	--	38875072(+)	`GGCCTA/C/GCAAGT`	3	Q E *	mis¹ stg¹		4		NA EU	5962
rs200653001^1,2		--	38875109(+)	`GAGCCA/GGACAG`	2	S	syn¹		0	--	--	--	--
rs145910727^1,2	C,F	--	38875159(+)	`GGTGGA/GTGTGC`	2	P S	mis¹		1		NA	4546
rs182734848^1,2		--	38875248(+)	`CCCCAA/TATGAA`	1	--	int¹		0	--	--	--	--
rs144086396^1,2		--	38875270(+)	`CTGAAA/GGCTAT`	1	--	int¹		0	--	--	--	--
rs11083454^1,2	C,F,H	--	38875482(+)	`TTGTCC/TCCCTG`	1	--	int¹		12		NS EA NA CSA	1664
rs188610914^1,2		--	38875599(+)	`GAGGGA/GTCAGG`	1	--	int¹		0	--	--	--	--
rs191786084^1,2		--	38875868(+)	`GTGTCC/TCCCTT`	1	--	int¹		0	--	--	--	--
rs78554911^1,2	C,F	--	38875871(+)	`TCCCCC/TTTTCC`	1	--	int¹		1		WA	118

HapMap Linkage Disequilibrium report for GGN (38874905 - 38878722 bp)

Structural Variations
Database of Genomic Variants (DGV) 7 variations for GGN: About this table

Variant ID	Type	Subtype	PubMed ID
dgv3857n71	CNV	Loss	21882294
nsv833823	CNV	Loss	17160897
nsv911658	CNV	Loss	21882294
nsv833822	CNV	Loss	17160897
nsv911659	CNV	Loss	21882294
nsv911660	CNV	Gain	21882294
nsv470140	CNV	Gain	18288195

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GGN

DNA2.0 Custom Variant and Variant Library Synthesis for GGN

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

OMIM gene information: 609966 OMIM disorders: --

4 diseases for GGN: About MalaCards

hypospadias male infertility wiskott-aldrich syndrome infertility

1 disease from the University of Copenhagen DISEASES database for GGN:

Male infertility

GGN for disorders About GeneDecksing

Human Genome Epidemiology (HuGE) Navigator: GGN (47 documents)

Export disorders for GGN gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for GGN gene integrated from 9 sources:
(articles sorted by number of sources associating them with GGN)

Utopia: connect your pdf to the dynamic
world of online information

Mouse GGN1 and GGN3, two germ cell-specific proteins from the single gene Ggn, interact with mouse POG and play a role in spermatogenesis. (PubMed id 12574169)^{1, 2, 3} Lu B. and Bishop C.E. (2003)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)¹ Woods N.T....Monteiro A.N. (2012)
GGN1 in the testis and ovary and its variance within t he Australian fertile and infertile male population. (PubMed id 21114676)¹ Jamsai D....O'Bryan M.K. (2011)
Yeast two-hybrid screens imply that GGNBP1, GGNBP2 and OAZ3 are potential interaction partners of testicular germ cell-specific protein GGN1. (PubMed id 15642376)¹ Zhang J....Lu B. (2005)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 199720	HGNC: 18869	AceView: GGN	Ensembl:ENSG00000179168	euGenes: HUgn199720
ECgene: GGN	H-InvDB: GGN

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for GGN	Pharmacogenomics, SNPs, Pathways

Intellectual Property for GGN gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for GGN gene:
Search GeneIP for patents involving GGN

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section


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	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Protease Activity Assays and Reagents		Browse Recombinant/Natural Proteins
	Browse Stem Cell Products		Browse Tocris Biochemicals & Compounds
	Browse cDNA Clones		Browse Proteome Profiler Antibody Arrays

	Browse OriGene Antibodies		OriGene RNAi products in human, mouse, rat for GGN
	Browse OriGene qPCR primer pairs and template standards		Browse OriGene Protein Over-expression Lysates
	OriGene Custom Mass Spec		OriGene clones in human, mouse for GGN
	OriGene qSTAR qPCR primer pairs in human, mouse for GGN		Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
	OriGene ORF clones in mouse, rat for GGN		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for GGN		OriGene Custom Protein Services for GGN

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat GGN
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing GGN
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GGN
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat GGN
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat GGN
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat GGN

	GenScript Custom Purified and Recombinant Proteins Services for GGN		GenScript cDNA clones with any tag delivered in your preferred vector for GGN
	GenScript Custom Assay Services for GGN		GenScript Custom Superior Antibodies Services for GGN
	GenScript Custom overexpressing Cell Line Services for GGN		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in GGN promoter
	Search Chromatin IP Primers for GGN
	RT² qPCR Primer Assay in human, mouse, rat GGN
	GNC Network for GGN
	SABiosciences Custom PCR Arrays for GGN

Search Tocris compounds for GGN

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological Cell Lysates
	cDNA Clones for GGN
	4000+ Proteins
	Search Sino Biological for antibodies, proteins & pathways
	Protein Production Services
	Transfection Reagents
	Protein A/G/L resins
	Isotyping reagents

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	GGN antibodies
	GGN proteins
	GGN lysates

	Search for Antibodies for GGN at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for GGN
	Custom Antibody / Protein Production Service
	Bulk Purchasing
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	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

	Proteins for GGN
	Antibodies for GGN
	ELISAs for GGN
	CLIAs for GGN

Search LifeMap BioReagents cell lines for GGN

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GGN

	Browse SwitchGear 3'UTR luciferase reporter plasmids for GGN
	SwitchGear Promoter luciferase reporter plasmids for GGN

Search ThermoFisher Antibodies for GGN

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat GGN

	inGenious Targeting Laboratory - Custom generated mouse model solutions for GGN
	inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for GGN

Customized:

	lentivirus for stable overexpression of GGN
	lentivirus expression plasmids for stable overexpression of GGN
	adenovirus for overexpression of GGN

LSBio Antibodies in human, mouse, rat for GGN

Customized transgenic rodents for:

	Humanization
	Biomarker expression
	Off-target effect monitoring
	Translational medicine
	Tissue-specific gene expresssion
	Time-controlled gene expresssion

GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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Category			TGFB1 (GIFtS: 73) transforming growth factor, beta 1
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes GGN gene at Home site.

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Export list of displayed genes

GGN Gene

Gametogenetin

Aliasesfor GGN gene

Summariesfor GGN gene

Genomic Viewsfor GGN gene

Proteinsfor GGN gene

Protein Domains /Familiesfor GGN gene

Functionfor GGN gene

Pathways & Interactionsfor GGN gene

Drugs & Compoundsfor GGN gene

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Expression for GGN gene

Orthologsfor GGN gene

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Genome Databases showing GGN gene

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Specialized Databases showing GGN gene

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for GGN gene

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for GGN gene

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for GGN gene

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for GGN gene

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for GGN gene

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for GGN gene

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for GGN gene

Transcripts
for GGN gene

Expression
for GGN gene

Orthologs
for GGN gene

Paralogs
for GGN gene

Genomic Variants
for GGN gene

Disorders / Diseases
for GGN gene

Publications
for GGN gene

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for GGN gene

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for GGN gene