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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

GGA2 Gene

protein-coding GIFtS: 56
GCID: GC16M023474

golgi-associated, gamma adaptin ear containing, ARF binding...

Explore 1 disease affiliated with
GGA2 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Golgi-Associated, Gamma Adaptin Ear Containing, ARF Binding Protein 2¹ ²		VHS Domain And Ear Domain Of Gamma-Adaptin² ³
VEAR¹ ²		ADP-Ribosylation Factor-Binding Protein GGA2²
KIAA1080¹ ³		Golgi Associated, Gamma Adaptin Ear Containing, ARF Binding Protein 2²
Gamma-Adaptin-Related Protein 2² ³		VHS Domain And Ear Domain-Containing Protein²
Golgi-Localized, Gamma Ear-Containing, ARF-Binding Protein 2² ³		Vear³

External Ids:	HGNC: 16064¹	Entrez Gene: 23062²	Ensembl: ENSG00000103365⁷	OMIM: 606005⁵	UniProtKB: Q9UJY4³

Export aliases for GGA2 gene to outside databases

Previous GC identifers: GC16M022884 GC16M023563 GC16M023403 GC16M023442 GC16M023383 GC16M021565

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for GGA2:

This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family

includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the

lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate

receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of

gamma-adaptins. This family member may play a significant role in cargo molecules regulation and clathrin-coated

vesicle assembly. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: GGA2_HUMAN, Q9UJY4

Function: Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates

the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules

with a cytosolic acidic cluster-dileucine (AC-LL) motif

Gene Wiki entry for GGA2

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000016.9 NC_018927.1 NT_010393.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the GGA2 gene promoter:
GR Max1 TBP USF1 FOXF2 C/EBPalpha USF-1 GR-alpha MRF-2 c-Myc
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: GGA2 promoter sequence

Search SABiosciences Chromatin IP Primers for GGA2

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat GGA2

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16p12 Ensembl cytogenetic band: 16p12.2 HGNC cytogenetic band: 16p12

GGA2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
GGA2 gene location

GeneLoc information about chromosome 16 GeneLoc Exon Structure

GeneLoc location for GC16M023474: view genomic region (about GC identifiers)

Start:	23,474,863 bp from pter	End:	23,533,316 bp from pter
Size:	58,454 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: GGA2_HUMAN, Q9UJY4 (See protein sequence)

Recommended Name: ADP-ribosylation factor-binding protein GGA2

Size: 613 amino acids; 67150 Da

Subunit: Monomer. Interacts with NECAP1, TSG101, UBC and AFTPH/aftiphilin. Interacts with CNST (By similarity).

Interacts with GGA1 and GGA3. Binds to clathrin and activated ARFs. Binds RABEP1 and RABGEF1. Interacts with the

type-I membrane proteins SORT1, SORL1, LRP3, M6PR/CD-MPR, IGF2R/CI-MPR and BACE1. Binds the accessory proteins CCDC91,

P200, SYNRG, EPN4 and NECAP2

Subcellular location: Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Endosome membrane;

Peripheral membrane protein

Sequence caution: Sequence=AAK38634.1; Type=Frameshift; Positions=193;

1 PDB 3D structure from and Proteopedia for GGA2:

1MHQ (3D)

Secondary accessions: D3DWF0 O14564 Q9NYN2 Q9UPS2

Explore the universe of human proteins at neXtProt for GGA2: NX_Q9UJY4

Post-translational modifications:

Ubiquitinated (By similarity)¹

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9UJY4

GGA2 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_055859.1

ENSEMBL proteins:

ENSP00000311962 ENSP00000454455 ENSP00000454469 ENSP00000456247 ENSP00000455331

ENSP00000460975 ENSP00000455293 ENSP00000459560 ENSP00000459414

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	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Browse Proteins at Uscn

Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	--	--
GO:0005802	trans-Golgi network	IDA	10749927
GO:0010008	endosome membrane	IEA	--
GO:0030131	clathrin adaptor complex	IEA	--
GO:0030136	clathrin-coated vesicle	IDA	19478182

GGA2 for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

GGA2 for domains About GeneDecksing

5/7 InterPro domains/families (see all 7):

IPR002014 VHS

IPR004152 GAT

IPR018205 VHS_subgr

IPR013041 Coatomer/clathrin_app_Ig-like

IPR008152 Clathrin_a/b/g-adaptin_app_Ig

Graphical View of Domain Structure for InterPro Entry Q9UJY4

ProtoNet protein and cluster: Q9UJY4

4 Blocks protein families:

IPB002014 VHS

IPB004152 GAT domain

IPB008152 Alpha/gamma adaptin

IPB008153 Gamma-adaptin

UniProtKB/Swiss-Prot: GGA2_HUMAN, Q9UJY4

Domain: The VHS domain functions as a recognition module for sorting signals composed of an acidic cluster followed by

two leucines (AC-LL motif)

Domain: The GAT domain is responsible for interaction with ARF-GTP, UBC and RABEP1. Required for recruitment to the TGN

it prevents ARF-GTP hydrolysis

Domain: The unstructured hinge region contains clathrin-binding but no autoinhibitory (AC-LL) motifs

Domain: The GAE domain binds accessory proteins regulating GGAs function

Similarity: Belongs to the GGA protein family

Similarity: Contains 1 GAE domain

Similarity: Contains 1 GAT domain

Similarity: Contains 1 VHS domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: GGA2_HUMAN, Q9UJY4

Function: Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates

the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules

with a cytosolic acidic cluster-dileucine (AC-LL) motif

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		8/67 QIAGEN miScript miRNA Assays for microRNAs that regulate GGA2 (see all 67):
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Gene Editing
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GGA2

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	12429846
GO:0030306	ADP-ribosylation factor binding	IDA	10749927

GGA2 for ontologies About GeneDecksing

1 GenomeRNAi human phenotype for GGA2:

Decreased cilium length after

Animal Models:
3 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Gga2):

growth/size

homeostasis/metabolism

mortality/aging

GGA2 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Lysosome

Lysosome

1.00

Pathway sources
See GeneCards unified pathways
Show all pathways

1 Kegg Pathway (Kegg details for GGA2):

Lysosome

GGA2 for pathways About GeneDecksing

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for GGA2

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/73 Interacting proteins for GGA2 (Q9UJY4^{1, 2, 3} ENSP00000311962⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 73)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SPG21	Q9NZD8²^,³, ENSP00000204566⁴	MINT-66286 I2D: score=5 STRING: ENSP00000204566
SORT1	Q99523²^,³, ENSP00000256637⁴	MINT-15490 MINT-18373 MINT-15491 MINT-18374 I2D: score=3 STRING: ENSP00000256637
IGF2R	P11717²^,³, ENSP00000349437⁴	MINT-14276 MINT-18511 I2D: score=2 STRING: ENSP00000349437
RABEP1	Q15276¹^,²^,³, ENSP00000262477⁴	EBI-447646,EBI-447043 MINT-14026 I2D: score=5 STRING: ENSP00000262477
SORL1	Q92673²^,³, ENSP00000260197⁴	MINT-18468 MINT-18467 I2D: score=5 STRING: ENSP00000260197

About this table

Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006886	intracellular protein transport	NAS	10749927
GO:0016192	vesicle-mediated transport	IEA	--

GGA2 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for GGA2

1 HMDB Compound for GGA2 About this table

Compound	Synonyms	CAS #	PubMed Ids
Guanosine triphosphate	5'-GTP (see all 10)	86-01-1	--

Search CenterWatch for drugs/clinical trials and news about GGA2

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for GGA2 gene:

NM_015044.4

Unigene Cluster for GGA2:

Golgi-associated, gamma adaptin ear containing, ARF binding protein 2

Hs.460336 [show with all ESTs]

Unigene Representative Sequence: NM_015044

17 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000309859(uc002dlq.3 uc010bxo.2) ENST00000567468 ENST00000567339

ENST00000568922 ENST00000566685 ENST00000569182 ENST00000567201 ENST00000570111

ENST00000568799 ENST00000563494 ENST00000569300 ENST00000569189 ENST00000563047

ENST00000562944 ENST00000562117 ENST00000566651 ENST00000566547

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		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat GGA2
		8/67 QIAGEN miScript miRNA Assays for microRNAs that regulate GGA2 (see all 67):
		hsa-miR-100* hsa-miR-607 hsa-miR-4272 hsa-miR-146a hsa-miR-128 hsa-miR-578 hsa-miR-759 hsa-miR-298

		Browse SwitchGear 3'UTR luciferase reporter plasmids

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Additional cDNA sequence:

AB029003.1 AF165531.1 AF190863.1 AF233522.1 AK024619.1 AK026350.1 AK130752.1 AK308425.1

BC000284.1 BC050620.1

21 DOTS entries:

DT.97802848 DT.75137542 DT.91703648 DT.100753863 DT.92449212 DT.97791884 DT.99980049 DT.100823002

DT.120690982 DT.87017539 DT.99963378 DT.100823000 DT.102832972 DT.92055093 DT.100842910 DT.120691026

DT.40222209 DT.75135518 DT.91850677 DT.92449221 DT.100823003

24/486 AceView cDNA sequences (see all 486):

F09622 CB132425 BM708346 CR624601 CB529520 CR593083 AA679417 AI418016

BG678098 CA748504 C00613 AL548428 AB029003 AW571895 AF165531 BQ708271

CB322058 AA033756 BU689580 AI811668 AW515819 AI969910 AA504463 BQ070628

GeneLoc Exon Structure

5/11 Alternative Splicing Database (ASD) splice patterns (SP) for GGA2 (see all 11) About this scheme

ExUns:	1a	·	1b	·	1c	^	2a	·	2b	·	2c	^	3a	·	3b	·	3c	·	3d	^	4a	·	4b	·	4c	^	5a	·	5b	^	6	^	7	^	8	^	9	^	10	^	11	^	12	^	13	^	14	^	15	^	16a	·
SP1:											-				-		-		-		-												-										-
SP2:											-				-		-		-		-																						-
SP3:
SP4:											-				-		-		-		-
SP5:											-				-		-		-

ExUns:	16b	·	16c	^	17a	·	17b	^	18a	·	18b	^	19a	·	19b
SP1:									-
SP2:	-		-		-				-
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for GGA2

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

GGA2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

GGA2 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Lung

Trachea

Basal Cells

Lung

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See GGA2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for GGA2

SOURCE GeneReport for Unigene cluster: Hs.460336

UniProtKB/Swiss-Prot: GGA2_HUMAN, Q9UJY4

Tissue specificity: Ubiquitously expressed

SABiosciences Custom PCR Arrays for GGA2

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for GGA2

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for GGA2 gene from 5/21 species (see all 21) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	GGA2¹	golgi-associated, gamma adaptin ear containing, ARF more	62.13(n) 55.94(a)		416577 XM_414878.2 XP_414878.2
lizard (Anolis carolinensis)	Reptilia	GGA2⁶	--	68(a)	1 ↔ 1	AAWZ02038145(561-4708)
fruit fly (Drosophila melanogaster)	Insecta	CG3002³	--	32(a)		8F1 --
thale cress (Arabidopsis thaliana)	eudicotyledons	AT2G38410⁶ AT1G06210⁶ (see all 9)	ENTH/VHS/GAT family protein (see all 9)	9(a) 13(a) (see all 9)	many ↔ many many ↔ many (see all 9)	2(16086630-16090208) 1(1897203-1899208)
rice (Oryza sativa)	Liliopsida	-- -- (see all 10)	VHS and GAT domain containing protein, expressed (see all 10)	9(a) 9(a) (see all 10)	many ↔ many many ↔ many (see all 10)	2(9972640-9978097) 6(13161902-13170018)

ENSEMBL Gene Tree for GGA2 (if available)
TreeFam Gene Tree for GGA2 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for GGA2 gene

TOM1L2² TOM1L1² TOM1² GGA1² GGA3²

4 SIMAP similar genes for GGA2 using alignment to 7 protein entries: GGA2_HUMAN (see all proteins):

GGA1 TOM1L1 GGA3 TOM1

GGA2 for paralogs About GeneDecksing

1 Pseudogenes.org Pseudogene for GGA2
PGOHUM00000262283

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 16 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs141484348^1,2		--	23474474(+)	`GAGGGC/TTGCCA`	1	--	ds500¹		0	--	--	--	--
rs201289390^1,2		--	23474567(+)	`ACCCC-/AGAGTT`	1	--	ds500¹		0	--	--	--	--
rs147510056^1,2		--	23474596(+)	`AACACA/GTAAGT`	1	--	ds500¹		0	--	--	--	--
rs140040489^1,2		--	23474597(+)	`ACACAG/TAAGTG`	1	--	ds500¹		0	--	--	--	--
rs116538049^1,2	F,	--	23474634(+)	`GAAGAG/CAGCGG`	1	--	ds500¹		1		WA	118
rs185748907^1,2		--	23474641(+)	`GCGGGA/GTTATG`	1	--	ds500¹		0	--	--	--	--
rs369856^1,2	C,F,O,A,H,	--	23474664(+)	`TCATAC/TTGATA`	1	--	ds500¹		29		EA NA NS WA CSA	2983
rs191489282^1,2		--	23474734(+)	`ATACTA/GTATTT`	1	--	ds500¹		0	--	--	--	--
rs78606198^1,2		--	23474897(+)	`TTTTAG/TAAAGC`	1	--	ut3¹		0	--	--	--	--
rs115308394^1,2	F,	--	23474990(+)	`TGCATC/TGCTTG`	1	--	ut3¹		1		WA	118

HapMap Linkage Disequilibrium report for GGA2 (23474863 - 23533316 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for GGA2: --

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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GGA2 for disorders           About GeneDecksing

OMIM gene information: 606005    OMIM disorders: --

1 disease for GGA2:    About MalaCards

colon cancer

Export disorders for GGA2 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for GGA2 gene, integrated from 9 sources (see all 61):
(articles sorted by number of sources associating them with GGA2)

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A family of ADP-ribosylation factor effectors that can alter transport through the trans-Golgi. (PubMed id 10749927)^{1, 2, 3} Boman A.L.... Kahn R.A. (2000)
A family of proteins with gamma-adaptin and VHS domains that facilitate trafficking between the trans-Golgi network and the vacuole/lysosome. (PubMed id 10747088)^{1, 2, 3} Hirst J....Robinson M.S. (2000)
Crystal structure of GGA2 VHS domain and its implication in plasticity in the ligand binding pocket. (PubMed id 12606052)^{1, 2, 9} Zhu G.... Zhang X.C. (2003)
Biochemical and structural characterization of the interaction of memapsin 2 (beta-secretase) cytosolic domain with the VHS domain of GGA proteins. (PubMed id 14567678)^{1, 2, 9} He X.... Tang J. (2003)
Interactions of GGA3 with the ubiquitin sorting machinery. (PubMed id 15039775)^{1, 2} Puertollano R. and Bonifacino J.S. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Definition of the consensus motif recognized by gamma-adaptin ear domains. (PubMed id 14665628)^{1, 2} Mattera R.... Bonifacino J.S. (2004)
Binding partners for the COOH-terminal appendage domains of the GGAs and gamma-adaptin. (PubMed id 12808037)^{1, 2} Lui W.W.Y.... Robinson M.S. (2003)
Mammalian GGAs act together to sort mannose 6-phosphate receptors. (PubMed id 14638859)^{1, 2} Ghosh P.... Kornfeld S. (2003)
Divalent interaction of the GGAs with the Rabaptin-5-Rabex-5 complex. (PubMed id 12505986)^{1, 2} Mattera R.... Bonifacino J.S. (2003)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 23062	HGNC: 16064	AceView: GGA2	Ensembl:ENSG00000103365	euGenes: HUgn23062
ECgene: GGA2	Kegg: 23062	H-InvDB: GGA2

(According to HUGE)
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HUGE: KIAA1080

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for GGA2	Pharmacogenomics, SNPs, Pathways

Intellectual Property for GGA2 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for GGA2 gene:
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GeneCards and IP:
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